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The New England Journal of Medicine, ISSN 0028-4793, 10/2012, Volume 367, Issue 14, pp. 1297 - 1309
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2006, Volume 355, Issue 21, pp. 2203 - 2216
In this trial, patients with acute coronary syndromes undergoing an early invasive approach were randomly assigned to treatment with heparin or enoxaparin plus... 
MEDICINE, GENERAL & INTERNAL | INHIBITION | MYOCARDIAL-INFARCTION | REPLACE-2 RANDOMIZED-TRIAL | STRATEGY | PLATELET GLYCOPROTEIN-IIB/IIIA | UNSTABLE ANGINA | ST-SEGMENT ELEVATION | BLOCKADE | INTERVENTION | UNFRACTIONATED HEPARIN | Recombinant Proteins - therapeutic use | Humans | Middle Aged | Heparin - therapeutic use | Male | Enoxaparin - therapeutic use | Recombinant Proteins - adverse effects | Angioplasty, Balloon, Coronary | Angina, Unstable - drug therapy | Aged, 80 and over | Adult | Female | Drug Therapy, Combination | Myocardial Ischemia - epidemiology | Kaplan-Meier Estimate | Anticoagulants - therapeutic use | Anticoagulants - adverse effects | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Hirudins - adverse effects | Angina, Unstable - therapy | Coronary Artery Bypass | Aged | Peptide Fragments - adverse effects | Peptide Fragments - therapeutic use | Hemorrhage - chemically induced | Aggregation | Evaluation | Blood platelets | Drug therapy | Coronary heart disease | Heart attacks | Medical imaging | Mortality | Informed consent | Clinical medicine | Angina pectoris | Acute coronary syndromes | Health education | Patients | Bypass cardiopulmonar | Bypass cardiopulmonary | Malalties coronàries | Anticoagulants (Medicine) | Heparin | Heparina | Anticoagulants (Medicina) | Coronary diseases
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2012, Volume 366, Issue 1, pp. 20 - 33
In this trial, vorapaxar, a protease-activated–receptor 1 antagonist that inhibits thrombin-induced platelet activation, was not effective in reducing the... 
MEDICINE, GENERAL & INTERNAL | PLACEBO | GLYCOPROTEIN IIB/IIIA INHIBITORS | CLOPIDOGREL | TASK-FORCE | SAFETY | DOUBLE-BLIND | ANTIPLATELET THERAPY | Follow-Up Studies | Angioplasty | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | Pyridines - adverse effects | Cardiovascular Diseases - mortality | Female | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Pyridines - therapeutic use | Double-Blind Method | Receptor, PAR-1 - antagonists & inhibitors | Kaplan-Meier Estimate | Combined Modality Therapy | Lactones - adverse effects | Lactones - therapeutic use | Acute Coronary Syndrome - drug therapy | Intracranial Hemorrhages - chemically induced | Coronary Artery Bypass | Acute Coronary Syndrome - therapy | Aged | Hemorrhage - chemically induced | Antagonists (Biochemistry) | Drugs | Dose-response relationship (Biochemistry) | Dosage and administration | Product/Service Evaluations | Drug therapy | Coronary heart disease | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | Proteinase-activated receptor 1 | Thrombin | Cardiovascular disease | Hemorrhage | Bleeding | Investigations | Manuscripts | Ischemia | Blood platelets | Acute coronary syndromes | Research centers | Malalties cardiovasculars | Bypass cardiopulmonar | Medicaments | Bypass cardiopulmonary | Plaquetes sanguínies | Cardiovascular diseases | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 07/2016, Volume 134, Issue 4, pp. 304 - 313
Journal Article