Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (83) 83
Publication (20) 20
Book Review (9) 9
Newspaper Article (5) 5
Book Chapter (3) 3
Book / eBook (2) 2
Dissertation (2) 2
Patent (2) 2
Conference Proceeding (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (41) 41
humans (38) 38
apoptosis (21) 21
cancer (19) 19
cell biology (18) 18
article (13) 13
expression (13) 13
proteins (13) 13
lung cancer (12) 12
animals (11) 11
apoptosis - drug effects (11) 11
biochemistry & molecular biology (11) 11
cell line (11) 11
cell line, tumor (11) 11
lung neoplasms - pathology (11) 11
proto-oncogene proteins c-bcl-2 - metabolism (10) 10
reactive oxygen species - metabolism (10) 10
lung neoplasms - metabolism (9) 9
cell proliferation - drug effects (8) 8
lung (8) 8
oncology (8) 8
s-nitrosylation (8) 8
activation (7) 7
bcl-2 (7) 7
female (7) 7
kinases (7) 7
nitric oxide (7) 7
physiology (7) 7
stem cells (7) 7
bleomycin (6) 6
breast cancer (6) 6
cancer therapies (6) 6
cell culture (6) 6
lung neoplasms - drug therapy (6) 6
nf-kappa-b (6) 6
nitric oxide - metabolism (6) 6
oxidative stress (6) 6
angiogenesis (5) 5
blotting, western (5) 5
caspases - metabolism (5) 5
death (5) 5
digitoxin (5) 5
drugs (5) 5
hydrogen-peroxide (5) 5
lung neoplasms - genetics (5) 5
male (5) 5
mice (5) 5
pharmacology & pharmacy (5) 5
pharmacy (5) 5
proto-oncogene proteins c-akt - metabolism (5) 5
respiratory tract diseases (5) 5
signal transduction - drug effects (5) 5
tumors (5) 5
vascular endothelial growth factor (5) 5
antineoplastic agents - pharmacology (4) 4
apoptosis - physiology (4) 4
c-flip (4) 4
cardiac glycosides (4) 4
casp8 and fadd-like apoptosis regulating protein - metabolism (4) 4
cell cycle (4) 4
cell death (4) 4
cell movement - drug effects (4) 4
cell survival - drug effects (4) 4
chemoresistance (4) 4
degradation (4) 4
glycosides (4) 4
hydroxyurea (4) 4
inhibition (4) 4
macroautophagy (4) 4
mediated apoptosis (4) 4
metastasis (4) 4
nitric-oxide (4) 4
pathway (4) 4
pathways (4) 4
phosphatidylinositol 3-kinases - metabolism (4) 4
proteasomal degradation (4) 4
proto-oncogene proteins c-bcl-2 - genetics (4) 4
pulmonary fibrosis (4) 4
pulmonary fibrosis - chemically induced (4) 4
signal transduction (4) 4
superoxide (4) 4
superoxides - metabolism (4) 4
therapy (4) 4
toxicology (4) 4
transfection (4) 4
viability (4) 4
akt (3) 3
analysis (3) 3
anticancer properties (3) 3
apoptosis regulatory proteins - metabolism (3) 3
articles (3) 3
autolysosome (3) 3
breast neoplasms - drug therapy (3) 3
cancer cells (3) 3
casp8 and fadd-like apoptosis regulating protein - genetics (3) 3
caspase-8 activation (3) 3
cell transformation, neoplastic - metabolism (3) 3
cell transformation, neoplastic - pathology (3) 3
cell-death (3) 3
chemotherapy (3) 3
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Anti‐Tumorigenic Potential of a Novel Orlistat‐AICAR Combination in Prostate Cancer Cells
by Wright, Clayton and Iyer, Anand Krishnan V and Kaushik, Vivek and Azad, Neelam
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2017, Volume 118, Issue 11, pp. 3834 - 3845
The potentiation of Orlistat cytotoxicity using AICAR in PCa cells is proposed. Apoptosis is enhanced, and cell viability and proliferation is decreased. The... 
PROSTATE CANCER (PCa) | AMPK | AICAR | ORLISTAT | FATTY ACID SYNTHASE | TARGET | APOPTOSIS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | COENZYME-A | DNA-REPLICATION | CELL BIOLOGY | INHIBITION | GROWTH | FATTY-ACID SYNTHASE | ANDROGEN RECEPTOR GENE | EXPRESSION | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Ribonucleotides - metabolism | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Male | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Lactones - pharmacology | Cell Movement - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Cell Line, Tumor | Resting Phase, Cell Cycle - drug effects | Aminoimidazole Carboxamide - metabolism | G1 Phase Cell Cycle Checkpoints - drug effects | Prostatic Neoplasms - drug therapy | Proteins | Synthesis | Orlistat | Hypoglycemic agents | Fatty acids | Prostate cancer | Vascular endothelial growth factor | Protein binding | AMP | Pharmacology | Kinases | AMP-activated protein kinase | Cancer therapies | Fatty-acid synthase | Anticancer properties | Cell activation | Cell cycle | Sterol regulatory element-binding protein | Prostate | Viability | Regulatory proteins | Cancer | Apoptosis | Index Medicus | Fatty Acid Synthase | Prostate cancer (PCa)
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text S‐Nitrosylation of Bcl‐2 Negatively Affects Autophagy in Lung Epithelial Cells
by Wright, Clayton and Iyer, Anand Krishnan V and Kulkarni, Yogesh and Azad, Neelam
Journal of Cellular Biochemistry, ISSN 0730-2312, 02/2016, Volume 117, Issue 2, pp. 521 - 532
Autophagy is a catabolic cellular mechanism involving lysosomal degradation of unwanted cellular components. Interaction between Beclin-1 and Bcl-2 proteins is... 
BCL‐2 | AUTOPHAGY | NITRIC OXIDE | BECLIN‐1 | NITROSYLATION | BCL-2 | S-NITROSYLATION | BECLIN-1 | PATHWAYS | APOPTOSIS | PROTEASOMAL DEGRADATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHROMIUM | CANCER | CELL BIOLOGY | CARCINOGENESIS | THERAPY | MALIGNANT-TRANSFORMATION | NITRIC-OXIDE | PROTEINS | Cell Line | Cysteine - analogs & derivatives | Proto-Oncogene Proteins c-bcl-2 - metabolism | Humans | Alveolar Epithelial Cells - metabolism | Cysteine - metabolism | Protein Processing, Post-Translational | p38 Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide - metabolism | S-Nitrosothiols - metabolism | Autophagy | Proteins | Cysteine | Nitric oxide | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Chemoresistance of Lung and Breast Cancer Cells Growing Under Prolonged Periods of Serum Starvation
by Yakisich, Juan Sebastian and Venkatadri, Rajkumar and Azad, Neelam and Iyer, Anand Krishnan V
Journal of Cellular Physiology, ISSN 0021-9541, 08/2017, Volume 232, Issue 8, pp. 2033 - 2043
Cancer cells growing under prolonged periods of serum starvation (PPSS) become multidrug resistant. Under PPSS cancer cells respond aberrantly and... 
ED AMERICAN-COLLEGE | BCL-2 | STEM-CELLS | SIDE POPULATION | PHYSIOLOGY | OBATOCLAX MESYLATE | MULTIDRUG-RESISTANCE | PACLITAXEL-RESISTANCE | LINES | P-GLYCOPROTEIN | MDR1 EXPRESSION | CELL BIOLOGY | Lung Neoplasms - drug therapy | Paclitaxel - pharmacology | Drug Resistance, Multiple - drug effects | Humans | Lung Neoplasms - metabolism | Digitoxin - pharmacology | Lung Neoplasms - pathology | Neoplasm Proteins - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Breast Neoplasms - metabolism | Culture Media, Serum-Free - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | MCF-7 Cells | Time Factors | Female | Antineoplastic Agents - pharmacology | Cell Culture Techniques | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Lung Neoplasms - genetics | Cell Survival - drug effects | Drug Resistance, Multiple - genetics | Breast Neoplasms - drug therapy | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - genetics | Drug Resistance, Neoplasm - genetics | Breast Neoplasms - genetics | Energy Metabolism | Signal Transduction - drug effects | Breast Neoplasms - pathology | Models, Biological | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Cell Proliferation - drug effects | ATP Binding Cassette Transporter, Sub-Family B - genetics | Proto-Oncogene Proteins c-bcl-2 - genetics | Drug Resistance, Neoplasm - drug effects | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Cancer Cell Plasticity: Rapid Reversal of Chemosensitivity and Expression of Stemness Markers in Lung and Breast Cancer Tumorspheres
by Yakisich, Juan Sebastian and Azad, Neelam and Kaushik, Vivek and Iyer, Anand Krishnan V
Journal of Cellular Physiology, ISSN 0021-9541, 09/2017, Volume 232, Issue 9, pp. 2280 - 2286
In this report, we have developed a protocol to grow lung and breast cancer cells as floating tumorspheres (FTs) in the absence of any external mitogenic... 
SOX2 | BCL-2 | NETWORK | PHYSIOLOGY | ASSAY | RESISTANCE | SELF-RENEWAL | PROLIFERATION | TUMORIGENICITY | CELL BIOLOGY | Lung Neoplasms - drug therapy | Cell Plasticity - drug effects | Cell Proliferation | Drug Resistance, Multiple | Neoplastic Stem Cells - drug effects | Humans | Lung Neoplasms - metabolism | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Breast Neoplasms - metabolism | Culture Media, Serum-Free - metabolism | Dose-Response Relationship, Drug | MCF-7 Cells | Neoplastic Stem Cells - metabolism | Time Factors | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Female | Antineoplastic Agents - pharmacology | Spheroids, Cellular | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Down-Regulation | Breast Neoplasms - drug therapy | Cell Adhesion | Phenotype | Signal Transduction - drug effects | Breast Neoplasms - pathology | Protein Kinase Inhibitors - pharmacology | Epidermal Growth Factor - pharmacology | Proteins | Drug resistance in microorganisms | Breast cancer | Analysis | Cell culture | Media (culture) | Computer simulation | Lung cancer | Chemoresistance | Media | Stimulation | Environmental factors | Drug resistance | Environmental conditions | Breast | Plastic properties | Cancer | Index Medicus | plasticity | chemoresistance | cancer | stemness | tumorspheres
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Anti-Tumorigenic Potential of a Novel Orlistat-AICAR Combination in Prostate Cancer Cells
: ORLISTAT -AICAR INDUCES PCa CELL DEATH
by Wright, Clayton and Iyer, Anand Krishnan V and Kaushik, Vivek and Azad, Neelam
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2017, Volume 118, Issue 11, pp. 3834 - 3845
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Chemoresistance of cancer floating cells is independent of their ability to form 3D structures: Implications for anticancer drug screening
by Kaushik, Vivek and Yakisich, Juan S and Way, Lillian Frances and Azad, Neelam and Iyer, Anand K. V
Journal of Cellular Physiology, ISSN 0021-9541, 04/2019, Volume 234, Issue 4, pp. 4445 - 4453
Three‐dimensional (3D) culture systems such as floating spheroids (FSs) and floating tumorspheres (FTs) are widely used as tumor models of chemoresistance. FTs... 
two‐dimensional (2D) culture | chemoresistance | three‐dimensional (3D) culture | spheroids | drug screening | three-dimensional (3D) culture | two-dimensional (2D) culture | SIDE POPULATION | PHYSIOLOGY | IDENTIFICATION | CELL BIOLOGY | TUMOR SPHEROIDS | STEM-LIKE CELLS | MODELS | RESISTANCE | EXPRESSION | Cell culture | Biotechnology | Tumor cells | Lung | Lung cancer | Chemoresistance | Hydroxyurea | Tumor cell lines | Drug screening | Floating | Floating structures | E-cadherin | Spheroids | Cell lines | Colchicine | Prostate | Cancer | Tumors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Abstract 1300: Fatty acid synthase (FASN) inhibition negatively affects cell proliferation and the metastatic capability of prostate cancer cells
by Wright, Clayton and Iyer, Anand Krishnan V and Azad, Neelam
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 1300 - 1300
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Abstract 277: Broad-spectrum anticancer activities of the biguanides metformin and buformin in combination with 2-deoxy-glucose or WZB-117 in human lung cancer cells
by Yakisich, Juan Sebastian and Azad, Neelam and Iyer, Anand V
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 277 - 277
Purpose: The biguanides Metformin (MET) and to a lesser extent Buformin (BUF) have recently been shown to exert anticancer effects. In particular MET targets... 
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Anti-tumorigenic effects of resveratrol in lung cancer cells through modulation of c-FLIP
by Wright, Clayton and Iyer, Anand Krishnan V and Yakisich, Juan S and Azad, Neelam
Current Cancer Drug Targets, ISSN 1568-0096, 2017, Volume 17, Issue 7, pp. 669 - 680
Background: Resveratrol has been shown to have antioxidant and anti-proliferative properties in multiple cancer types. Here we demonstrate that H460 lung... 
C-FLIP | Hydrogen peroxide | Akt | Lung cancer | Resveratrol | Apoptosis | SIGNALING PATHWAYS | INHIBITORY PROTEIN | 3-KINASE | hydrogen peroxide | apoptosis | DEATH | FAS-MEDIATED APOPTOSIS | CASPASE-8 ACTIVATION | ONCOLOGY | TRAIL-INDUCED APOPTOSIS | resveratrol | c-FLIP | NF-KAPPA-B | TUMOR-GROWTH | EXPRESSION | Lung Neoplasms - drug therapy | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Stilbenes - pharmacology | Apoptosis Regulatory Proteins - metabolism | Hydrogen Peroxide - metabolism | Cell Line, Tumor | Antineoplastic Agents, Phytogenic - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Cell proliferation | Lung | AKT protein | Activation | Kinases | Antioxidants | Transfection | Epidermal growth factor | Catalase | FLIP protein | Inhibition | Vascular endothelial growth factor | NF-κB protein | Epidermal growth factor receptors | Caspase | Poly(ADP-ribose) polymerase | c-FLIP protein | Caspase-8 | Proteasomes | Viability | Cancer
Journal Article
Details down arrow
10. Full Text Anti‐Tumor Effects of Cardiac Glycosides on Human Lung Cancer Cells and Lung Tumorspheres
by Kaushik, Vivek and Yakisich, Juan Sebastian and Azad, Neelam and Kulkarni, Yogesh and Venkatadri, Rajkumar and Wright, Clayton and Rojanasakul, Yon and Iyer, Anand Krishnan V
Journal of Cellular Physiology, ISSN 0021-9541, 09/2017, Volume 232, Issue 9, pp. 2497 - 2507
The cardiac glycosides convallatoxin and peruvoside exert potent anti‐cancer effects in lung cancer cells. A significant inhibition of cell migration,... 
BREAST-CANCER | APOPTOSIS | ACTIVATION | PHYSIOLOGY | CONVALLATOXIN | 3-KINASE | PATHWAY | GROWTH | NA+/K+-ATPASE | RAPID DETECTION | DIGITOXIN | CELL BIOLOGY | Lung Neoplasms - genetics | Cell Survival - drug effects | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Neoplasm Invasiveness | Humans | Lung Neoplasms - metabolism | Tumor Suppressor Protein p53 - metabolism | Epithelial-Mesenchymal Transition - drug effects | Lung Neoplasms - pathology | Autophagy - drug effects | Tumor Suppressor Protein p53 - genetics | Dose-Response Relationship, Drug | Cell Movement - drug effects | Strophanthins - pharmacology | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Spheroids, Cellular | Cardenolides - pharmacology | Cardiotonic agents | Lung cancer | Analysis | Cancer cells | Development and progression | Respiratory agents | Tumor proteins | Cardiac glycosides | Tumors | Drugs | Cell survival | Leukocyte migration | p53 Protein | Lung | Floating | Anticancer properties | Proteins | Pathways | Cell cycle | Glycosides | Biomarkers | Tumor suppressor genes | Bioindicators | Heart diseases | Viability | Cell migration | Phagocytosis | Cancer | G1 phase | Glucosides | Apoptosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Reactive Oxygen Species Mediate Caspase Activation and Apoptosis Induced by Lipoic Acid in Human Lung Epithelial Cancer Cells through Bcl-2 Down-Regulation
by Jirapan Moungjaroen and Ubonthip Nimmannit and Patrick S. Callery and Liying Wang and Neelam Azad and Vimolmas Lipipun and Pithi Chanvorachote and Yon Rojanasakul
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2006, Volume 319, Issue 3, pp. 1062 - 1069
The antioxidant α-lipoic acid (LA) is a naturally occurring compound that has been shown to possess promising anticancer activity because of its ability to... 
SUPPLEMENTATION | OXIDATIVE STRESS | NECROSIS | PROTEIN | ANTIOXIDANT | MITOCHONDRIA | INJURY | PHARMACOLOGY & PHARMACY | HYDROGEN-PEROXIDE | HYPERTENSION | DAMAGE | Lung Neoplasms - drug therapy | Oxidants - pharmacology | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Caspases - metabolism | Transfection | Superoxide Dismutase - physiology | Genes, bcl-2 - physiology | Plasmids - genetics | Thioctic Acid - pharmacology | Mitochondria - metabolism | Mitochondria - drug effects | Down-Regulation - drug effects | Enzyme Activation - drug effects | Blotting, Western | Glutathione Peroxidase - genetics | Hydrogen Peroxide - metabolism | Glutathione Peroxidase - physiology | Cell Line, Tumor | Genes, bcl-2 - drug effects | Superoxide Dismutase-1 | Enzyme Activation - physiology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Chemoresistance of cancer floating cells is independent of their ability to form 3D structures: Implications for anticancer drug screening
: KAUSHIK et al
by Kaushik, Vivek and Yakisich, Juan S and Way, Lillian Frances and Azad, Neelam and Iyer, Anand K. V
Journal of Cellular Physiology, ISSN 0021-9541, 04/2019, Volume 234, Issue 4, pp. 4445 - 4453
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Autophagy‐Induced Apoptosis in Lung Cancer Cells by a Novel Digitoxin Analog
by Kulkarni, Yogesh M and Kaushik, Vivek and Azad, Neelam and Wright, Clayton and Rojanasakul, Yon and O'Doherty, George and Iyer, Anand Krishnan V
Journal of Cellular Physiology, ISSN 0021-9541, 04/2016, Volume 231, Issue 4, pp. 817 - 828
We have synthesized a novel derivative of Digitoxin, termed "MonoD", which demonstrates cytotoxic effects in lung cancer cells with much higher potency as... 
SUPEROXIDE | PHYSIOLOGY | THERAPY | PROTEASOMAL DEGRADATION | BAD | PHOSPHORYLATION | CYTOSOLIC LC3 RATIO | DEATH | MACROAUTOPHAGY | BCL-2 FAMILY | TUMORIGENESIS | CELL BIOLOGY | Biomarkers - metabolism | Cell Survival - drug effects | Digoxigenin - analogs & derivatives | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Digitoxin - pharmacology | Lung Neoplasms - pathology | Vacuoles - drug effects | Autophagy - drug effects | Digoxigenin - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Digitoxin - analogs & derivatives | Models, Biological | Superoxides - metabolism | Cell Line, Tumor | Vacuoles - metabolism | Cell Proliferation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Proteins | Superoxide | Lung cancer | Cancer cells | Apoptosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Abstract 4164: Resveratrol-induced apoptosis in breast cancer cells is mediated by tumor suppressor microRNA
by Muni, Tanvi and Iyer, Anand and Azad, Neelam
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 4164 - 4164
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text S-Nitrosylation of Bcl-2 Negatively Affects Autophagy in Lung Epithelial Cells
: S-NITROSYLATIONOFBCL-2 NEGATIVELYAFFECTSAUTOPHAGY
by Wright, Clayton and Iyer, Anand Krishnan V and Kulkarni, Yogesh and Azad, Neelam
Journal of Cellular Biochemistry, ISSN 0730-2312, 02/2016, Volume 117, Issue 2, pp. 521 - 532
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Nitric Oxide Mediates Bleomycin‐induced Angiogenesis and Pulmonary Fibrosis via Regulation of VEGF
by Iyer, Anand Krishnan V and Ramesh, Vani and Castro, Carlos A and Kaushik, Vivek and Kulkarni, Yogesh M and Wright, Clayton A and Venkatadri, Rajkumar and Rojanasakul, Yon and Azad, Neelam
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2015, Volume 116, Issue 11, pp. 2484 - 2493
Pulmonary fibrosis is a progressive lung disease hallmarked by increased fibroblast proliferation, amplified levels of extracellular matrix deposition and... 
BLEOMYCIN | ANGIOGENESIS | NITRIC OXIDE | PULMONARY FIBROSIS | VEGF | APOPTOSIS | MATRIX | COLLAGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | RAT LUNG FIBROSIS | CELL BIOLOGY | DISEASE | DEGRADATION | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Human Umbilical Vein Endothelial Cells | Cell Line | Humans | Peptides, Cyclic - pharmacology | Endothelial Growth Factors - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Liver Cirrhosis, Experimental - genetics | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Peptides, Cyclic - administration & dosage | Endothelial Growth Factors - administration & dosage | Neovascularization, Pathologic - pathology | Liver Cirrhosis, Experimental - prevention & control | Animals | Signal Transduction - drug effects | Liver Cirrhosis, Experimental - pathology | Neovascularization, Pathologic - genetics | Neovascularization, Pathologic - prevention & control | Mice | Neovascularization, Pathologic - metabolism | Nitric Oxide - metabolism | Liver Cirrhosis, Experimental - metabolism | Bleomycin - toxicity | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text MnTBAP Inhibits Bleomycin‐Induced Pulmonary Fibrosis by Regulating VEGF and Wnt Signaling
by Venkatadri, Rajkumar and Iyer, Anand Krishnan V and Ramesh, Vani and Wright, Clayton and Castro, Carlos A and Yakisich, Juan S and Azad, Neelam
Journal of Cellular Physiology, ISSN 0021-9541, 03/2017, Volume 232, Issue 3, pp. 506 - 516
In this study, we investigated the anti‐fibrotic effects of MnTBAP, a MnSOD mimetic on bleomycin‐induced pulmonary fibrosis. We demonstrate that MnTBAP... 
OXIDATIVE STRESS | ACTIVATION | PHYSIOLOGY | ANGIOGENESIS | INFLAMMATION | ATTENUATION | DISEASE | ANTIOXIDANT ENZYMES | LUNG-FUNCTION | MECHANISMS | EXPRESSION | CELL BIOLOGY | Biomarkers - metabolism | Cell Line | Neovascularization, Physiologic - drug effects | Humans | Mice, Inbred C57BL | Pulmonary Fibrosis - pathology | Vascular Endothelial Growth Factor A - metabolism | Metalloporphyrins - pharmacology | Up-Regulation - drug effects | Metalloporphyrins - therapeutic use | Animals | Bleomycin | Wnt Signaling Pathway - drug effects | Calcium Signaling - drug effects | Pulmonary Fibrosis - chemically induced | Pulmonary Fibrosis - metabolism | Pulmonary Fibrosis - drug therapy | Benzoic acid | Pulmonary fibrosis | Endothelial growth factors | Respiratory tract diseases | Superoxide | Organic acids | Oxidative stress | Peroxynitrite | Wnt protein | Lung | Crosstalk | Lung diseases | Upstream | Superoxide dismutase | In vitro testing | Calcium signalling | Signal transduction | Chloride | Pathways | Fibrosis | In vivo methods and tests | Interferon | Vascular endothelial growth factor | Manganese | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
18. Full Text Phosphatidylinositol-3-kinase/Akt regulates bleomycin-induced fibroblast proliferation and collagen production
by Lu, Yongju and Azad, Neelam and Wang, Liying and Iyer, Anand K. V and Castranova, Vincent and Jiang, Bing-Hua and Rojanasakul, Yon
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 04/2010, Volume 42, Issue 4, pp. 432 - 441
Abnormal repair and dysregulated angiogenesis have been implicated in the pathogenesis of pulmonary fibrosis, but the underlying mechanisms of regulation are... 
Bleomycin | Akt | PI3K | Collagen | ROS | bleomycin | HYPOXIA-INDUCIBLE FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | collagen | ANTIOXIDANT ENZYMES | TUMOR ANGIOGENESIS | PROTEIN-KINASE B | CELL BIOLOGY | FACTOR 1-ALPHA | RESPIRATORY SYSTEM | CELL-MIGRATION | IDIOPATHIC PULMONARY-FIBROSIS | NF-KAPPA-B | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Transcription, Genetic - drug effects | Fibroblasts - enzymology | Reactive Oxygen Species - metabolism | Antibiotics, Antineoplastic - pharmacology | Antioxidants - metabolism | Humans | Antibiotics, Antineoplastic - adverse effects | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Lung - enzymology | Neovascularization, Pathologic - pathology | Neovascularization, Pathologic - enzymology | Collagen - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - biosynthesis | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Oxidoreductases - metabolism | Enzyme Inhibitors - pharmacology | Bleomycin - adverse effects | Neovascularization, Pathologic - chemically induced | Enzyme Activation - drug effects | Fibroblasts - pathology | Pulmonary Fibrosis - enzymology | Pulmonary Fibrosis - chemically induced | Bleomycin - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights