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Molecular Systems Biology, ISSN 1744-4292, 2013, Volume 9, Issue 1, pp. 700 - n/a
The evolution of resistance to a single antibiotic is frequently accompanied by increased resistance to multiple other antimicrobial agents. In sharp contrast,... 
collateral sensitivity network | trade off | evolutionary experiment | antibiotic resistance | Antibiotic resistance | PERMEABILITY | ENTERICA SEROVAR TYPHIMURIUM | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | SUSCEPTIBILITY | SALMONELLA | AMINOGLYCOSIDE | RESISTANCE | MULTIDRUG EFFLUX | STAPHYLOCOCCUS-AUREUS | Genome, Bacterial | Escherichia coli - drug effects | Selection, Genetic | Anti-Bacterial Agents - metabolism | Escherichia coli Proteins - metabolism | Drug Resistance, Microbial - genetics | Biological Evolution | Microbial Sensitivity Tests | Aminoglycosides - metabolism | Biological Transport | Metabolic Networks and Pathways | Escherichia coli - genetics | Membrane Transport Proteins - genetics | Escherichia coli - metabolism | Escherichia coli Proteins - genetics | Membrane Transport Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Cell Membrane - metabolism | High-Throughput Nucleotide Sequencing | Mutation | Aminoglycosides - pharmacology | Cell Membrane - drug effects | Laboratories | Genes | Aminoglycosides | Genomes | Biosynthesis | Drug resistance | Experiments | Gene sequencing | Proteins | E coli | Evolution | Aminoglycoside antibiotics | Adaptation | Efflux | Integrated approach | Hypersensitivity | Antimicrobial agents | Acids | Antibiotics | Plasmids | Protein synthesis | Sensitivity enhancement | Transporter | Life Sciences | Medication | Pharmaceutical sciences
Journal Article
Journal Article
Magyar Zene, ISSN 0025-0384, 11/2006, Volume 44, Issue 4, pp. 417 - 437
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 4/2012, Volume 132, Issue 3, pp. 1025 - 1034
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0165244
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 11607
A central challenge in evolutionary biology concerns the mechanisms by which complex metabolic innovations requiring multiple mutations arise. Here, we propose... 
Biological Evolution | Metabolic Networks and Pathways - genetics | Models, Genetic | Escherichia coli - genetics | Adaptation, Biological - genetics | Escherichia coli - metabolism
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2018, Volume 115, Issue 25, pp. E5726 - E5735
Journal Article