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1. Full Text The effect of foetal growth restriction on the development of migraine and tension-type headache in adulthood. The HUNT Study
by Børte, Sigrid and Winsvold, Bendik S and Stensland, Synne Øien and Småstuen, Milada Cvancarova and Zwart, John-Anker
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0175908
Background There is little knowledge about how factors early in life affect the development of migraine and tension-type headache. We aimed to examine whether... 
GESTATIONAL-AGE | BORN SMALL | MULTIDISCIPLINARY SCIENCES | BIRTH-WEIGHT | POTENTIAL MECHANISMS | SYMPTOMS | SEX-DIFFERENCES | INTRAUTERINE GROWTH | CHILDHOOD | EPIDEMIOLOGY | CHILDREN | Tension-Type Headache - epidemiology | Humans | Risk Factors | Fetal Growth Retardation - epidemiology | Migraine Disorders - diagnosis | Logistic Models | Male | Gestational Age | Pregnancy | Young Adult | Birth Weight | Tension-Type Headache - diagnosis | Health Surveys | Fetal Growth Retardation - etiology | Norway - epidemiology | Migraine Disorders - complications | Adult | Female | Registries | Tension-Type Headache - complications | Odds Ratio | Infant, Newborn | Migraine Disorders - epidemiology | Tension headache | Demographic aspects | Growth | Migraine | Physiological aspects | Fetus | Research | Risk factors | Brain | Neonates | Inventories | Physical activity | Pathogenesis | Disorders | Cognitive ability | Body measurements | Infants | Hormones | Gender | Classification | Inhibition | Health promotion | Violence | Abnormalities | Fetuses | Rats | Metabolism | Catecholamine | Studies | Sex hormones | Neurology | Hospitals | Placenta | Nursing | Clinical medicine | Cardiovascular diseases | Health risk assessment | Developed countries | Rubella | Multiple births | Headache | Congenital defects | Epilepsy | Headaches | Prenatal development | Population studies | Infections | Developing countries--LDCs | Vascular diseases | Cerebral blood flow | Questionnaires | Children | Excitation | Malnutrition | Age | Congenital diseases | Health | Complications | Aggression | Diabetes mellitus | Blood flow | Medicine | Neurotransmitters | Brain research | Birth weight | Inhabitants | LDCs | Developing countries
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2. Full Text Parental migraine in relation to migraine in offspring: Family linkage analyses from the HUNT Study
by Børte, Sigrid and Zwart, John-Anker and Stensland, Synne Øien and Hagen, Knut and Winsvold, Bendik S
Cephalalgia, ISSN 0333-1024, 6/2019, Volume 39, Issue 7, pp. 854 - 862
Background Migraine is known to run in families. While some clinical studies have indicated that migraine is disproportionally transmitted through the maternal... 
epidemiology | Migraine | all headache
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3. Full Text Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families
by Gormley, Padhraig and Kurki, Mitja and Kurki, Mitja I and Hiekkala, Marjo and Hiekkala, Marjo Eveliina and Veerapen, Kumar and Häppölä, Paavo and Mitchell, Adele A and Lal, Dennis and Palta, Priit and Surakka, Ida and Kaunisto, Mari Anneli and Kaunisto, Mari and Hämäläinen, Eija and Vepsäläinen, Salli and Havanka, Hannele and Harno, Hanna and Ilmavirta, Matti and Nissilä, Markku and Säkö, Erkki and Sumelahti, Marja-Liisa and Liukkonen, Jarmo and Sillanpää, Matti and Metsähonkala, Liisa and Koskinen, Seppo and Lehtimäki, Terho and Raitakari, Olli and Männikkö, Minna and Ran, Caroline and Belin, Andrea Carmine and Jousilahti, Pekka and Anttila, Verneri and Salomaa, Veikko and Artto, Ville and Färkkilä, Markus and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and Furlotte, Nick and Huber, Karen E and Kleinman, Aaron and Litterman, Nadia K and Litterman, Nadia and McCreight, Jennifer C and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie and Northover, Carrie A.M and Pitts, Steven J and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Boomsma, Dorret I and Børte, Sigrid and Chasman, Daniel I and Cherkas, Lynn and Christensen, Anne Francke and Cormand, Bru and Cuenca-Leon, Ester and Davey-Smith, George and Dichgans, Martin and van Duijn, Cornelia and Esko, Tonu and Esserlind, Ann-Louise and Ferrari, Michel D and Frants, Rune R and Freilinger, Tobias and Griffiths, Lyn and Hamalainen, Eija and Hansen, Thomas Folkmann and Ikram, M Arfan and Ingason, Andres and Järvelin, Marjo-Riitta and Kajanne, Risto and Kallela, Mikko and Kaprio, Jaakko and Kubisch, Christian and Kurth, Tobias and Launer, Lenore and Lehtimaki, Terho and Lessel, Davor and Ligthart, Lannie and van den Maagdenberg, Arn and Macaya, Alfons and Malik, Rainer and Mangino, Massimo and McMahon, George and Muller-Myhsok, Bertram and Neale, Benjamin M and Nyholt, Dale R and ... and Int Headache Genetics Consortium and 23me Res Team and 23andMe Research Team and International Headache Genetics Consortium (IHGC)
Neuron, ISSN 0896-6273, 05/2018, Volume 98, Issue 4, pp. 743 - 753.e4
Complex traits, including migraine, often aggregate in families, but the underlying genetic architecture behind this is not well understood. The aggregation... 
PRS | migraine | GWAS | genome-wide association study | familial aggregation | migraine with aura | hemiplegic migraine | disease aggregation | families | polygenic risk score | Neuroscience(all) | HEMIPLEGIC MIGRAINE | POPULATION | METAANALYSIS | DISEASE | 38 SUSCEPTIBILITY LOCI | GENETIC ARCHITECTURE | ANALYSES IDENTIFY | TYPE-2 | NEUROSCIENCES | CARDIOVASCULAR RISK | GENOME-WIDE ASSOCIATION | Migraine | Genetic aspects | Studies | Headache | Disease | Headaches | Population | Genomes | Heredity | Mutation | Polygenic inheritance
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4. Full Text Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
by Gormley, A.M and Stefansson, Hreinn and Winsvold, Bendik and Palta, Priit and Esko, Tõnu and Pers, Tune and Farh, Kai-How and Cuenca-Leon, E and Muona, M and Furlotte, N.A and Kurth, Karl and Ingason, Anes and Mcmahon, George and Ligthart, Lannie and Terwindt, Gisela and Todt, Unda and Müller-Myhsok, Bertram and Ran, C and Gordon, S.G and Stam, Anine and Steinberg, Stacy and Göbel, Hartmut and Koiranen, Markku and Quaye, Lydia and Adams, H.H.H and Lehtimäki, Terho and Sarin, A.-P and Wedenoja, J and Hinds, David A and Buring, J.E and Schürks, Markus and Ridker, Paul and Hrafnsdottir, M.G and Ring, Susan and Hottenga, Jouke Jan and Penninx, Brenda and Färkkilä, Markus and Artto, Ville and Hämäläinen, Eija and Lucae, Susanne and Malik, Rainer and Heath, Anew C and Madden, Pamela and Martin, Nicholas and Montgomery, Grant and Kurki, M.I and Kals, Mart and Mägi, Reedik and Pärn, K and Huang, H and Byrnes, A.E and Franke, Lude and Huang, Jian and Stergiakouli, Evangelia and Lee, Phil and Sandor, C and Webber, C and Cader, Z and Müller-Myhsok, B and Schreiber, Stefan and Meitinger, Thomas and Hagen, Knut and Salomaa, Veikko and Heikkilä, Kauko and Loehrer, Elizabeth and Uitterlinden, Ané and Hofman, A and Duijn, Cornelia and Cherkas, Lynn and Pedersen, L.M and Stubhaug, A and Nielsen, C.S and Männikkö, M and Mihailov, Evelin and Milani, Lili and Esserlind, A.-L and Christensen, A.F and Hansen, T.F and Werge, Thomas and Kaprio, Jaakko and Aromaa, Arpo and Raitakari, Olli and Ikram, Arfan and Ikram, Kamran and Jarvelin, Marjo-Riitta and Metspalu, Anes and Kubisch, Christian and Strachan, David and Ferrari, Michel and Belin, A.C and Wessman, Maija and Maagdenberg, Arn and Zwart, John-Anker and Boomsma, Dorret and Smith, G.D and Stefansson, K and Eriksson, Nicholas and Daly, Mark and Neale, Benjamin and Olesen, Jes and ... and Int Headache Genetics Consortium and International Headache Genetics Consortium
Nature Genetics, ISSN 1061-4036, 08/2016, Volume 48, Issue 8, pp. 856 - 866
textabstractMigraine is a debilitating neurological disorder affecting around one in seven people worldwide, but its molecular mechanisms remain poorly... 
SYSTEMATIC ANALYSIS | MYOCARDIAL-INFARCTION | GENOTYPE IMPUTATION | GENETICS & HEREDITY | GENE-EXPRESSION | SMOOTH-MUSCLE-CELLS | FAMILIAL HEMIPLEGIC MIGRAINE | RECEPTOR-RELATED PROTEIN-1 | SINGLE-NUCLEOTIDE POLYMORPHISMS | SPREADING DEPRESSION | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Genome-Wide Association Study | Migraine Disorders - genetics | Genetic Markers - genetics | Genomics | Humans | Genetic Loci - genetics | Polymorphism, Single Nucleotide - genetics | Vascular Diseases - genetics | Muscle, Smooth - metabolism | Case-Control Studies | Quantitative trait loci | Genome-wide association studies | Migraine | Genetic aspects | Gene expression | Identification and classification | Health aspects | Risk factors | Methods | Studies | Confidence intervals | Consortia | Headaches | Gene loci | Genomes | Meta-analysis
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5. Full Text Parental migraine in relation to migraine in offspring: Family linkage analyses from the HUNT Study
by Børte, Sigrid and Zwart, John-Anker and Stensland, Synne Øien and Hagen, Knut and Winsvold, Bendik S
Cephalalgia : an international journal of headache, 02/2019, p. 333102419828989
Migraine is known to run in families. While some clinical studies have indicated that migraine is disproportionally transmitted through the maternal line, this... 
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6. Full Text The causal role of smoking on the risk of headache. A Mendelian randomization analysis in the HUNT Study
by Johnsen, Marianne Bakke and Winsvold, Bendik K S and Børte, Sigrid and Vie, Gunnhild Åberge and Pedersen, Linda Margareth and Storheim, Kjersti and Skorpen, Frank and Hagen, Knut and Bjørngaard, Johan Håkon and Åsvold, Bjørn Olav and Zwart, John-Anker
ISSN 1351-5101, 2018
Background and purpose: Headache has been associated with various lifestyle and psychosocial factors, one of which is smoking. The aim of the present study was... 
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7. Full Text Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
by Liu, Mengzhen and Jiang, Yu and Wedow, Robbee and Li, Yue and Brazel, David M and Chen, Fang and Datta, Gargi and Davila-Velderrain, Jose and McGuire, Daniel and Tian, Chao and Zhan, Xiaowei and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and Hinds, David A and Hromatka, Bethann S and Huber, Karen E and Kleinman, Aaron and Litterman, Nadia K and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie A.M and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Pitts, Steven J and Mitchell, Amy and Skogholt, Anne Heidi and Winsvold, Bendik Slagsvold and Sivertsen, Børge and Stordal, Eystein and Morken, Gunnar and Kallestad, Håvard and Heuch, Ingrid and Zwart, John Anker and Fjukstad, Katrine Kveli and Pedersen, Linda M and Gabrielsen, Maiken Elvestad and Johnsen, Marianne Bakke and Skrove, Marit and Inedavik, Marit Sæbø and nge, Ole Kristian and Bjerkeset, Ottar and Børte, Sigrid and Stensland, Synne Øien and Choquet, Hélène and Docherty, Anna R and Faul, Jessica D and Foerster, Johanna R and Fritsche, Lars G and Gordon, Scott D and Haessler, Jeffrey and Hottenga, Jouke Jan and Huang, Hongyan and Jang, Seon Kyeong and Jansen, Philip R and Ling, Yueh and Mägi, Reedik and Matoba, Nana and McMahon, George and Mulas, Antonella and Orrù, Valeria and Palviainen, Teemu and Pandit, Anita and Reginsson, Gunnar W and Smith, Jennifer A and Taylor, Amy E and Turman, Constance and Willemsen, Gonneke and Young, Hannah and Young, Kena A and Zajac, Gregory J.M and Zhao, Wei and Zhou, Wei and Bjornsdottir, Gyda and Boardman, Jason D and Boehnke, Michael and Boomsma, Dorret I and Chen, Chu and Cucca, Francesco and Davies, Gareth E and Eaton, Charles B and Ehringer, Marissa A and Esko, Tõnu and Fiorillo, Edoardo and Gillespie, Nathan A and Gudbjartsson, Daniel F and Haller, Toomas and Harris, Kathleen Mullan and Heath, Anew C and Hewitt, John K and ... and HUNT All In Psychiat and 23 Me Res Team and 23andMe Research Team and HUNT All-In Psychiatry
Nature Genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 237 - 244
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex diseases and disorders 1 . They are heritable 2,3 and... 
Genetics | RISK-FACTORS | GENOTYPE IMPUTATION | GLUTAMATE | DRUG-ADDICTION | GENETICS & HEREDITY | SMOKING | LD SCORE REGRESSION | HERITABILITY | CONSUMPTION | GENOME-WIDE ASSOCIATION | DEPENDENCE | Phenotype | Humans | Middle Aged | Female | Male | Risk | Smoking - genetics | Tobacco Use Disorder - genetics | Genetic Variation - genetics | Tobacco - adverse effects | Genome-Wide Association Study - methods | Alcohol Drinking - genetics | Usage | Analysis | Influence | Drinking of alcoholic beverages | Research | Health aspects | Causes and theories of causation | Risk factors | Diseases | Tobacco habit | Phenotypes | Dopamine | Genes | Health risks | Principal components analysis | Nervous system | Genomes | Loci | Alcohol use | Datasets | Substance use | Studies | Genetic variance | Signal transduction | Tobacco | Etiology | Alcoholic beverages | Glutamatergic transmission | Health risk assessment | Neurotransmission | Drug use | Dopamine receptors | Smoking
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8. Full Text The causal role of smoking on the risk of headache. A Mendelian randomization analysis in the HUNT study
by Johnsen, M. B and Winsvold, B. S and Børte, S and Vie, G. Å and Pedersen, L. M and Storheim, K and Skorpen, F and Hagen, K and Bjørngaard, J. H and Åsvold, B. O and Zwart, J. A
European Journal of Neurology, ISSN 1351-5101, 09/2018, Volume 25, Issue 9, pp. 1148 - e102
Background and purpose Headache has been associated with various lifestyle and psychosocial factors, one of which is smoking. The aim of the present study was... 
genetic variants | epidemiology | migraine | headache | smoking | NORD-TRONDELAG HEALTH | PREVALENCE | NEUROSCIENCES | CLINICAL NEUROLOGY | LIFE-STYLE | 15Q25 | QUESTIONNAIRE | ASSOCIATION | VALIDITY | Genetics | Single nucleotide polymorphisms | Epidemiology | Migraine | Confidence intervals | Headache | Randomization | Alleles | Headaches | Single-nucleotide polymorphism | Polymorphism | Smoking
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9. Full Text Double-blind, placebo-controlled randomized trial with adalimumab for treatment of juvenile onset ankylosing spondylitis (JoAS): Significant short term improvement
by Horneff, Gerd and Fitter, Sigrid and Foeldvari, Ivan and Minden, Kirsten and Kuemmerle-Deschner, Jasmin and Tzaribacev, Nicolay and Thon, Angelika and Borte, Michael and Ganser, Gerd and Trauzeddel, Rolf and Huppertz, Hans-Iko
Arthritis Research and Therapy, ISSN 1478-6354, 10/2012, Volume 14, Issue 5, pp. R230 - R230
Introduction: While adalimumab is licensed for ankylosing spondylitis (AS), open uncontrolled studies suggest therapeutic efficacy of TNF-inhibitors in... 
RHEUMATOID-ARTHRITIS | MULTICENTER | SULFASALAZINE | PRELIMINARY DEFINITION | PROLONGED EFFICACY | IDIOPATHIC ARTHRITIS | OPEN-LABEL | RHEUMATOLOGY | ETANERCEPT | ANTITUMOR NECROSIS FACTOR | FUNCTIONAL INDEX | Disability Evaluation | Severity of Illness Index | Blood Sedimentation | Antibodies, Monoclonal, Humanized - therapeutic use | Double-Blind Method | Humans | Spondylitis, Ankylosing - blood | Spondylitis, Ankylosing - drug therapy | Male | Treatment Outcome | Dose-Response Relationship, Drug | Magnetic Resonance Imaging | Adolescent | Female | Adalimumab | Child | Spondylitis, Ankylosing - pathology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Antirheumatic Agents - therapeutic use | Care and treatment | Medical examination | Clinical trials | Research | Backache | Blood | Tumor necrosis factor | Analysis | Pharmaceutical industry | Health aspects | Biotechnology industry | Ankylosing spondylitis
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10. Full Text Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families
by Gormley, Padhraig and Kurki, Mitja and Kurki, Mitja I and Hiekkala, Marjo and Hiekkala, Marjo Eveliina and Veerapen, Kumar and Häppölä, Paavo and Mitchell, Adele A and Lal, Dennis and Palta, Priit and Surakka, Ida and Kaunisto, Mari Anneli and Kaunisto, Mari and Hämäläinen, Eija and Vepsäläinen, Salli and Havanka, Hannele and Harno, Hanna and Ilmavirta, Matti and Nissilä, Markku and Säkö, Erkki and Sumelahti, Marja-Liisa and Liukkonen, Jarmo and Sillanpää, Matti and Metsähonkala, Liisa and Koskinen, Seppo and Lehtimäki, Terho and Raitakari, Olli and Männikkö, Minna and Ran, Caroline and Belin, Andrea Carmine and Jousilahti, Pekka and Anttila, Verneri and Salomaa, Veikko and Artto, Ville and Färkkilä, Markus and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and Furlotte, Nick and Huber, Karen E and Kleinman, Aaron and Litterman, Nadia K and Litterman, Nadia and McCreight, Jennifer C and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie and Northover, Carrie A.M and Pitts, Steven J and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Boomsma, Dorret I and Børte, Sigrid and Chasman, Daniel I and Cherkas, Lynn and Christensen, Anne Francke and Cormand, Bru and Cuenca-Leon, Ester and Davey-Smith, George and Dichgans, Martin and van Duijn, Cornelia and Esko, Tonu and Esserlind, Ann-Louise and Ferrari, Michel D and Frants, Rune R and Freilinger, Tobias and Griffiths, Lyn and Hamalainen, Eija and Hansen, Thomas Folkmann and Ikram, M Arfan and Ingason, Andres and Järvelin, Marjo-Riitta and Kajanne, Risto and Kallela, Mikko and Kaprio, Jaakko and Kubisch, Christian and Kurth, Tobias and Launer, Lenore and Lehtimaki, Terho and Lessel, Davor and Ligthart, Lannie and van den Maagdenberg, Arn and Macaya, Alfons and Malik, Rainer and Mangino, Massimo and McMahon, George and Muller-Myhsok, Bertram and Neale, Benjamin M and Nyholt, Dale R and ... and IHGC and 23 Me Res Team and 23andMe Research Team and International Headache Genetics Consortium (IHGC)
Neuron, ISSN 0896-6273, 09/2018, Volume 99, Issue 5, pp. 1098 - 1098
Complex traits, including migraine, often aggregate in families, but the underlying genetic architecture behind this is not well understood. The aggregation... 
NEUROSCIENCES | Headache | Migraine
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