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by Okbay, Aysu and Beauchamp, Jonathan and Fontana, M.A and Lee, James J and Pers, Tune and Rietveld, C.A and Turley, Patrick and Chen, G.-B and Emilsson, Valur and Meddens, S.F.W and Oskarsson, S and Pickrell, J.K and Thom, K and Timshel, P and Vlaming, Ronald and Abdellaoui, Abdel and Ahluwalia, Tarunveer Singh and Bacelis, Jonas and Baumbach, Clemens and Bjornsdottir, G and Brandsma, Johan and Pina Concas, M and Derringer, J and Furlotte, N.A and Galesloot, Tessel and Girotto, S and Gupta, R and Hall, Leanne M and Harris, Sarah and Hofer, E and Horikoshi, M and Huffman, Jennifer E and Kaasik, K and Kalafati, Ioanna-Panagiota and Karlsson, Robert and Kong, Augustine and Lahti, Jari and Lee, Sven and Deleeuw, C and Lind, Penelope and Lindgren, K.-O and Liu, T and Mangino, Massimo and Marten, Jonathan and Mihailov, Evelin and Miller, Mike and Most, Peter and Oldmeadow, Christopher and Payton, Antony and Pervjakova, Natalia and Peyrot, Wouter and Qian, Y and Raitakari, Olli and Rueedi, R and Salvi, E and Schmidt, B and Schraut, K.E and Shi, J and Smith, Albert Vernon and Poot, Raymond and St Pourcain, Beate and Teumer, Alexander and Thorleifsson, Gudmar and Verweij, Niek and Vuckovic, gana and Wellmann, J and Westra, Harm-Jan and Yang, J and Zhao, W and Zhu, Z and Alizadeh, Behrooz and Amin, Najaf and Bakshi, A and Baumeister, Sebastian and Biino, G and Bønnelykke, Klaus and Boyle, Patricia and Campbell, Harry and Cappuccio, F.P and Davies, Gail and Neve, Jan-Emmanuel and Deloukas, Panagiotis and Demuth, Ilja and Ding, J and Eibich, P and Eisele, L and Eklund, Niina and Evans, David and Faul, Jessica D and Feitosa, Mary Furlan and Forstner, Aneas and Gandin, Ilaria and Gunnarsson, B and Halldorsson, Bjarni and Harris, Tamara and Holliday, Elizabeth and Heath, Anew C and Hocking, L.J and Homuth, Georg and Horan, Mike and ... and LifeLines Cohort Study and Humanistisk-samhällsvetenskapliga vetenskapsområdet and Uppsala universitet and Statsvetenskapliga institutionen and Samhällsvetenskapliga fakulteten
Nature: international weekly journal of science, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 539 - 542
Journal Article
Circulation, ISSN 0009-7322, 02/2006, Volume 113, Issue 6, pp. 834 - 841
Journal Article
by Okbay, Aysu and Baselmans, B.M.L and Neve, Jan-Emmanuel and Turley, Patrick and Nivard, Michel and Fontana, M.A and Meddens, S.F.W and Linnér, R.K and Rietveld, C.A and Derringer, J and Gratten, Jacob and Lee, James J and Liu, J.Z and Vlaming, Ronald and SAhluwalia, T and Buchwald, J and Cavadino, Alana and Frazier-Wood, Alexis C and Furlotte, N.A and Garfield, V and Geisel, M.H and Gonzalez, Juan R and Haitjema, S and Karlsson, Robert and Der Laan, S.W and Ladwig, Karl-Heinz and Lahti, Jari and Lee, Sven and Lind, Penelope and Liu, T and Matteson, L and Mihailov, Evelin and Miller, Mike and CMinica, C and MNolte, I and Mook-Kanamori, Dennis and Most, Peter and Oldmeadow, Christopher and Qian, Yong and Raitakari, Olli and Rawal, R and Realo, A and Rueedi, R and Schmidt, B and Smith, Albert Vernon and Stergiakouli, Evangelia and Tanaka, Toshiko and Taylor, Kent and Wedenoja, J and Wellmann, J and Westra, Harm-Jan and MWillems, S and Zhao, W and Study, LifeLines Cohort and Amin, Najaf and Bakshi, A and Boyle, Patricia and Cherney, S and Cox, S.R and Davies, Gail and Davis, Oliver S and Ding, Jun and Direk, Nese and Eibich, P and Emeny, Rebecca and Fatemifar, G and Faul, J.D and Ferrucci, Luigi and Forstner, Aneas and Gieger, Christian and Gupta, R and Harris, Tamara B and Harris, Juliette and Holliday, Elizabeth and Hottenga, Jouke Jan and Jager, Philip and Kaakinen, Marika and Kajantie, Eero and Karhunen, V and Kolcic, Ivana and Kumari, Meena and Launer, Lenore and Franke, Lude and Li-Gao, R and Koini, M and Loukola, Anu and Marques-Vidal, P and Montgomery, Grant and Mosing, Miriam and Paternoster, Lavinia and Pattie, Alison and Petrovic, Katja and Pulkki-R'back, L and Quaye, Lydia and R'ikkönen, K and Rudan, Igor and Scott, Rodney and Smith, Jennifer A and Sutin, A.R and Trzaskowski, M and ... and LifeLines Cohort Study
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 624 - 633
Journal Article
Circulation, ISSN 0009-7322, 05/2011, Volume 123, Issue 17, pp. 1891 - 1899
Background-Blocking of glycoprotein VI-dependent pathways by interfering in vascular collagen sites is commonly seen as an attractive target for an... 
stroke | platelet aggregation inhibitors | platelet adhesion | glycoprotein VI | platelet aggregation | CARDIAC & CARDIOVASCULAR SYSTEMS | FAB FRAGMENT | THROMBUS FORMATION | ACUTE CORONARY SYNDROME | ADHESION | CLOPIDOGREL | IN-VIVO | PERIPHERAL VASCULAR DISEASE | SOLUBLE GPVI | MICE | HEMATOLOGY | ANTITHROMBOTIC PROTECTION | EXPRESSION | Injections, Intravenous | Cricetulus | Recombinant Fusion Proteins - adverse effects | Humans | Male | Immunoglobulin Fc Fragments - administration & dosage | Dose-Response Relationship, Drug | Young Adult | Platelet Aggregation Inhibitors - administration & dosage | Platelet Membrane Glycoproteins - administration & dosage | Adult | Platelet Membrane Glycoproteins - adverse effects | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - pharmacokinetics | Immunoglobulin Fc Fragments - adverse effects | Recombinant Fusion Proteins - administration & dosage | CHO Cells | Platelet Aggregation Inhibitors - adverse effects | Hemostasis - drug effects | Platelet Membrane Glycoproteins - pharmacokinetics | Cricetinae | Glycoproteins - administration & dosage | Collagen - administration & dosage | Animals | Platelet Count | Recombinant Fusion Proteins - pharmacokinetics | Aggregation | Safety and security measures | Blood platelets | Hemostasis | Patient outcomes | Atherosclerosis | Dosage and administration | Research | Drug therapy | Index Medicus | Abridged Index Medicus
Journal Article
by Cornelius A. Rietveld and Sarah E. Medland and Jaime Derringer and Jian Yang and Tõnu Esko and Nicolas W. Martin and Harm-Jan Westra and Konstantin Shakhbazov and Abdel Abdellaoui and Arpana Agrawal and Eva Albrecht and Behrooz Z. Alizadeh and Najaf Amin and John Barnard and Sebastian E. Baumeister and Kelly S. Benke and Lawrence F. Bielak and Jeffrey A. Boatman and Patricia A. Boyle and Gail Davies and Christiaan de Leeuw and Niina Eklund and Daniel S. Evans and Rudolf Ferhmann and Krista Fischer and Christian Gieger and Håkon K. Gjessing and Sara Hägg and Jennifer R. Harris and Caroline Hayward and Christina Holzapfel and Carla A. Ibrahim-Verbaas and Erik Ingelsson and Bo Jacobsson and Peter K. Joshi and Astanand Jugessur and Marika Kaakinen and Stavroula Kanoni and Juha Karjalainen and Ivana Kolcic and Kati Kristiansson and Zoltán Kutalik and Jari Lahti and Sang H. Lee and Peng Lin and Penelope A. Lind and Yongmei Liu and Kurt Lohman and Marisa Loitfelder and George McMahon and Pedro Marques Vidal and Osorio Meirelles and Lili Milani and Ronny Myhre and Marja-Liisa Nuotio and Christopher J. Oldmeadow and Katja E. Petrovic and Wouter J. Peyrot and Ozren Polašek and Lydia Quaye and Eva Reinmaa and John P. Rice and Thais S. Rizzi and Helena Schmidt and Reinhold Schmidt and Albert V. Smith and Jennifer A. Smith and Toshiko Tanaka and Antonio Terracciano and Matthijs J. H. M. van der Loos and Veronique Vitart and Henry Völzke and Jürgen Wellmann and Lei Yu and Wei Zhao and Jüri Allik and John R. Attia and Stefania Bandinelli and François Bastardot and Jonathan Beauchamp and David A. Bennett and Klaus Berger and Laura J. Bierut and Dorret I. Boomsma and Ute Bültmann and Harry Campbell and Christopher F. Chabris and Lynn Cherkas and Mina K. Chung and Francesco Cueca and Mariza de Andrade and Philip L. De Jager and Jan-Emmanuel De Neve and Ian J. Deary and George V. Dedoussis and Panos Deloukas and Maria Dimitriou and Guðný Eiríksdóttir and Martin F. Elderson and Johan G. Eriksson and ... and LifeLines Cohort Study and The LifeLines Cohort Study and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper
Science, ISSN 0036-8075, 6/2013, Volume 340, Issue 6139, pp. 1467 - 1471
Journal Article
by Lee, James J and Wedow, Robbee and Okbay, Aysu and Kong, Edward and Maghzian, Omeed and Zacher, Meghan and Nguyen-Viet, Tuan Anh and Bowers, Peter and Sidorenko, Julia and Karlsson Linnér, Richard and Fontana, Mark Alan and Kundu, Tushar and Lee, Chanwook and Li, Hui and Li, Ruoxi and Royer, Rebecca and Timshel, Pascal N and Walters, Raymond K and Willoughby, Emily A and Yengo, Loïc and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Hinds, David A and McCreight, Jennifer C and Huber, Karen E and Litterman, Nadia K and McIntyre, Matthew H and Mountain, Joanna L and Noblin, Elizabeth S and Northover, Carrie A. M and Pitts, Steven J and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Vacic, Vladimir and Wilson, Catherine H and Okbay, Aysu and Beauchamp, Jonathan P and Fontana, Mark Alan and Lee, James J and Pers, Tune H and Rietveld, Cornelius A and Turley, Patrick and Chen, Guo-Bo and Emilsson, Valur and Meddens, S. Fleur W and Oskarsson, Sven and Pickrell, Joseph K and Thom, Kevin and Timshel, Pascal and Vlaming, Ronald de and Abdellaoui, Abdel and Ahluwalia, Tarunveer S and Bacelis, Jonas and Baumbach, Clemens and Bjornsdottir, Gyda and Brandsma, Johannes H and Concas, Maria Pina and Derringer, Jaime and Furlotte, Nicholas A and Galesloot, Tessel E and Girotto, Giorgia and Gupta, Richa and Hall, Leanne M and Harris, Sarah E and Hofer, Edith and Horikoshi, Momoko and Huffman, Jennifer E and Kaasik, Kadri and Kalafati, Ioanna P and Karlsson, Robert and Kong, Augustine and Lahti, Jari and van der Lee, Sven J and Leeuw, Christiaan de and Lind, Penelope A and Lindgren, Karl-Oskar and Liu, Tian and Mangino, Massimo and Marten, Jonathan and Mihailov, Evelin and Miller, Michael B and van der Most, Peter J and Oldmeadow, Christopher and Payton, Antony and Pervjakova, Natalia and Peyrot, Wouter J and Qian, Yong and Raitakari, Olli and Rueedi, Rico and Salvi, Erika and Schmidt, Börge and Schraut, Katharina E and ... and 23Me Res Team and Social Sci Genetic Assoc Consortiu and COGENT Cognitive Genomics Consorti and 23andMe Research Team and COGENT (Cognitive Genomics Consortium) and Social Science Genetic Association Consortium and Humanistisk-samhällsvetenskapliga vetenskapsområdet and Uppsala universitet and Statsvetenskapliga institutionen and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 08/2018, Volume 50, Issue 8, pp. 1112 - 1121
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2005, Volume 94, Issue 3, pp. 555 - 561
Summary Cell adhesion and proteolytic matrix degradation are central processes in atherosclerosis. Being a member of the family of ADAMs (“ a disintegrin a nd... 
Platelets and Blood Cells | Integrin | ADAM15 | Platelets | Atherosclerosis | Endothelium | atherosclerosis | endothelium | METARGIDIN | DOMAIN | PROTEIN | CD40 LIGAND | platelets | SPERM-EGG FUSION | ADAM-15 | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | integrin | HEMATOLOGY | EXPRESSION | GLYCOPROTEIN-IIB-IIIA
Journal Article