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Molecular Systems Biology, ISSN 1744-4292, 12/2019, Volume 15, Issue 12, pp. e9376 - n/a
Molecular Systems Biology warmly welcomes its new academic Chief Editor, M. Madan Babu. Madan shared his thoughts on the evolution of the field and the... 
Journal Article
SCIENCE, ISSN 0036-8075, 03/2018, Volume 359, Issue 6380, pp. 1105 - 1106
Protein-protein interactions form the molecular basis for organismal development and function (1, 2). In cells, protein interactions are dynamic and subject to... 
DRUG | CELLS | THERMAL SHIFT ASSAY | NETWORK | STABILITY | MULTIDISCIPLINARY SCIENCES | Protein Binding | Biophysical Phenomena | Proteins | Denaturation | Proteomics | Dynamic stability | Cell cycle | Mutation | Protein interaction | Disease control | Thermal stability | Binding sites
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 12/2018, Volume 14, Issue 12, pp. e8741 - n/a
The widespread application of sequencing technologies, used for example to obtain data from healthy individuals or patient cohorts, has led to the... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | Nucleotides | Proteins | Data processing | Mutation | Protein structure | Predictions
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 04/2019, Volume 15, Issue 4, p. n/a
Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane‐less... 
phase separation | natural selection | phenotypic diversity | cell fitness | protein deposit | SEQUENCE DETERMINANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEX COACERVATION | YEAST | GREEN FLUORESCENT PROTEIN | NUCLEAR-BODIES | GENE-EXPRESSION | MISFOLDED PROTEINS | INHERITANCE | STRESS GRANULES | AGGREGATION | Genètica | Fitnes | Selecció natural | Fenotip | Proteïnes
Journal Article
Journal Article
Cell, ISSN 0092-8674, 09/2018, Volume 175, Issue 1, pp. 40 - 42
Although there is much focus on the impact of mutations on structured protein domains, less is known about their impact on unstructured regions. In this issue,... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY
Journal Article
Molecular systems biology, 04/2019, Volume 15, Issue 4, p. e8075
Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane-less... 
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 06/2017, Volume 42, Issue 6, p. 410
Intrinsically disordered proteins (IDPs) can protect cells from diverse stresses by forming higher order assemblies such as reversible aggregates or granules.... 
Proteins | Stresses | Microorganisms | Aggregates | Granular materials | Desiccation | Granules | Forming | Amorphous materials | Stress | Cells | Drying
Journal Article
Seminars in Cell and Developmental Biology, ISSN 1084-9521, 2018
Genes and gene products interact with each other to form signal transduction networks in the cell. The interactome networks are under intricate regulation in... 
Signaling pathways | Interactome and regulome | Genetic mutations | Protein interactions | Network perturbations
Journal Article
Cell Reports, ISSN 2211-1247, 07/2018, Volume 24, Issue 3, pp. 557 - 568.e5
Despite the wealth of genetic information available, mechanisms underlying pathological effects of disease-associated mutations in components of G... 
ACTIVATION | PATHOGENICITY | ADENYLYL-CYCLASE | G-PROTEINS | GENETIC-VARIANTS | MUTATIONS | DYSTONIA | RECEPTORS | MULTIPLE SEQUENCE ALIGNMENT | DRUG TARGETS | CELL BIOLOGY
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7654, p. 317
Journal Article
Journal Article
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, p. 667
Journal Article