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Science, ISSN 0036-8075, 02/2015, Volume 347, Issue 6224, pp. 842 - 847
Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts that are typically created picoseconds after an... 
REPAIR | PATHWAY | MULTIDISCIPLINARY SCIENCES | DEGRADATION | RISK | ULTRAVIOLET | INDUCTION | DAMAGE | ACTS | DNA | Ultraviolet radiation | Physiological aspects | Genetic research | Research | Nucleotide sequencing | Health aspects | Melanin | DNA sequencing | Sun | Deoxyribonucleic acid--DNA | Mutations | Compounding | Deoxyribonucleic acid | Exposure | Damage | Ultraviolet | Compounds | Physics
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2012, Volume 44, Issue 9, pp. 1006 - 1014
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2015, Volume 47, Issue 9, pp. 996 - 1002
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2018, Volume 128, Issue 2, pp. 715 - 720
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 08/2016, Volume 99, Issue 2, pp. 443 - 450
Journal Article
Pigment Cell and Melanoma Research, ISSN 1755-1471, 04/2010, Volume 23, Issue 2, pp. 190 - 200
P>BRAFV600E/K is a frequent mutationally active tumor-specific kinase in melanomas that is currently targeted for therapy by the specific inhibitor PLX4032.... 
Drug response | Melanoma | ERK pathway | Serum markers | BRAF | RAF1 | Cell migration | drug response | melanoma | HETERODIMERIZATION | CANCER | CELL BIOLOGY | DERMATOLOGY | TARGETED THERAPIES | KIT | cell migration | serum markers | RAF-1 | ONCOGENE ADDICTION | MELANOCYTES | REVEALS | Original
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 03/2014, Volume 27, Issue 2, pp. 253 - 262
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2009, Volume 4, Issue 2, pp. e4563 - e4563
Journal Article
Oncotarget, ISSN 1949-2553, 03/2019, Volume 10, Issue 23, pp. 2237 - 2251
The major drawback of melanoma therapy with BRAF and MAPK inhibitors is the innate and acquired drug resistance. We therefore explored alternative targets and... 
Journal Article