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humans (104) 104
microbiology (97) 97
index medicus (85) 85
helicobacter pylori (82) 82
bacterial proteins - metabolism (61) 61
virulence (49) 49
animals (48) 48
phosphorylation (45) 45
biochemistry & molecular biology (44) 44
bacteria (39) 39
helicobacter pylori - pathogenicity (37) 37
proteins (37) 37
gastric epithelial-cells (36) 36
pathogenicity island (36) 36
bacterial proteins - genetics (35) 35
helicobacter pylori - metabolism (35) 35
signal transduction (35) 35
helicobacter pylori - genetics (34) 34
antigens, bacterial - metabolism (32) 32
cell biology (30) 30
molecular pathogenesis (30) 30
iv secretion (29) 29
e-cadherin (28) 28
epithelial cells - microbiology (28) 28
pathogens (28) 28
protein (27) 27
immunology (26) 26
infection (26) 26
secretion (26) 26
helicobacter infections - microbiology (25) 25
research (25) 25
helicobacter infections (24) 24
host-pathogen interactions (24) 24
tyrosine phosphorylation (24) 24
genetic aspects (23) 23
activation (22) 22
cell line (22) 22
infectious diseases (22) 22
inflammation (22) 22
molecular sequence data (22) 22
analysis (21) 21
bacterial infections and mycoses (21) 21
caga (21) 21
cancer (21) 21
gastroenterology & hepatology (21) 21
medicine (21) 21
type iv secretion (21) 21
health aspects (20) 20
infections (20) 20
kinases (20) 20
cell line, tumor (19) 19
signaling (19) 19
virulence factors (19) 19
bacterial proteins - chemistry (18) 18
epithelial cells (18) 18
epithelial-cells (18) 18
integrins (18) 18
amino acid sequence (17) 17
epithelial cells - metabolism (17) 17
expression (17) 17
gastric mucosa - microbiology (17) 17
helicobacter pylori - physiology (17) 17
htra (17) 17
virulence factors - metabolism (17) 17
campylobacter (16) 16
gastric cancer (16) 16
helicobacter infections - metabolism (16) 16
identification (16) 16
mice (16) 16
bacterial adhesion (15) 15
biochemistry (15) 15
chemistry (15) 15
translocation (15) 15
antigens, bacterial - genetics (14) 14
caga protein (14) 14
nf-kappa-b (14) 14
pathogenesis (14) 14
proteases (14) 14
stomach cancer (14) 14
biology (13) 13
cag pathogenicity island (13) 13
colonization (13) 13
digestive system diseases (13) 13
fibronectin (13) 13
gastritis (13) 13
molecular biology (13) 13
tyrosine (13) 13
apoptosis (12) 12
host-cell (12) 12
hygiene (12) 12
metallurgy (12) 12
protein binding (12) 12
antigens, bacterial (11) 11
article (11) 11
cell adhesion & migration (11) 11
cells, cultured (11) 11
escherichia-coli (11) 11
helicobacter-pylori (11) 11
human necessities (11) 11
induction (11) 11
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1. Inflammasome Signaling and Bacterial Infections
by Backert, Steffen and SpringerLink (Online service)
2016, Current Topics in Microbiology and Immunology, ISBN 9783319411712, Volume 397
This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and... 
Medicine | Parasitology | Infectious diseases | Respiratory organs | Medical microbiology | Diseases
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2. Inflammasome Signaling and Bacterial Infections
by Backert, Steffen and SpringerLink (Online service)
2016, Current Topics in Microbiology and Immunology, ISBN 9783319411712, Volume 397
This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and... 
Medicine | Parasitology | Infectious diseases | Respiratory organs | Medical microbiology | Diseases
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3. Molecular Pathogenesis and Signal Transduction by Helicobacter pylori
by Tegtmeyer, Nicole and Backert, Steffen and SpringerLink (Online service)
2017, Current Topics in Microbiology and Immunology, ISBN 331950519X, Volume 400
This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading... 
Medicine | Cancer research | Medical microbiology | Gastroenterology
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4. Type IV Secretion in Gram-Negative and Gram-Positive Bacteria
by Backert, Steffen and Grohmann, Elisabeth and SpringerLink (Online service)
2017, Current Topics in Microbiology and Immunology, ISBN 3319752405, Volume 413
Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver... 
Medicine | Immunology | Infectious diseases | Medical microbiology | Gastroenterology
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5. Helicobacter pylori research
: from bench to bedside
by Backert, Steffen and Yamaoka, Yoshio
2016, ISBN 9784431559344
Helicobacter pylori | Helicobacter Infections
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6. Helicobacter pylori research
: from bench to bedside
by Backert, Steffen and Yamaoka, Yoshio
2016, ISBN 9784431559344
Helicobacter pylori infections | Helicobacter pylori | Helicobacter Infections
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7. Full Text Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter Pylori
by Backert, Steffen
06/2019, ISBN 9783030151379, 378
Inflammation
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8. Microbial food safety
: an introduction
by Oyarzabal, Omar A and Backert, Steffen
2012, Food science text series, ISBN 9781461411765
Prevention | Microbiology | Food contamination | Food Safety | Safety measures | Food Microbiology | Food
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9. Full Text Inflammasome Signaling and Bacterial Infections
by Backert, Steffen
08/2016, Current Topics in Microbiology and Immunology, ISBN 3319411705, Volume 397, 288
This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and... 
Pneumology | Medical Microbiology | Infectious Diseases | Parasitology | Biomedicine | Pneumology/Respiratory System | Bacterial diseases | Inflammation
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10. Full Text How many protein molecules are secreted by single Helicobacter pylori cells: Quantification of serine protease HtrA
by Neddermann, Matthias and Backert, Steffen
Cellular Microbiology, ISSN 1462-5814, 07/2019, Volume 21, Issue 7, pp. e13022 - n/a
Infection with Helicobacter pylori represents a major risk for developing peptic ulcer disease, gastric adenocarcinoma, and various other gastric and... 
VacA | secretion | Helicobacter pylori | serine protease HtrA | signalling | Proteins | Thrombin | Virulence (Microbiology) | Serine | Temperature requirements | Adenocarcinoma | Cell culture | Protein purification | Epithelial cells | Secretion | Virulence | Health risks | Sicknesses | Secretome | Western blotting | Virulence factors | Protease | Liquid culture | Bacteria | Serine proteinase | Tumors
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11. Microbial food safety
: an introduction
by Oyarzabal, Omar A and Backert, Steffen
2012, Food science text series., ISBN 9781461411765, x, 262
Prevention | Microbiology | Food contamination | Safety measures | Food
Book
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12. Full Text Role of type IV secretion in Helicobacter pylori pathogenesis
by Backert, Steffen and Selbach, Matthias
Cellular Microbiology, ISSN 1462-5814, 08/2008, Volume 10, Issue 8, pp. 1573 - 1581
Summary Helicobacter pylori is a highly successful human-specific gastric pathogen that colonizes more than half the world's population. Infection with this... 
GROWTH-FACTOR RECEPTOR | ACTIVATION | PROTEIN | TYROSINE PHOSPHORYLATION | VIRULENCE FACTORS | HOST-CELL | MICROBIOLOGY | GASTRIC EPITHELIAL-CELLS | KAPPA-B | BETA-CATENIN | CAG PATHOGENICITY ISLAND | CELL BIOLOGY | Animals | Virulence Factors - genetics | Helicobacter pylori - metabolism | Humans | Bacterial Proteins - genetics | Helicobacter pylori - pathogenicity | Bacterial Proteins - metabolism | Virulence Factors - metabolism | Antigens, Bacterial - genetics | Antigens, Bacterial - metabolism | Fimbriae, Bacterial - metabolism | Helicobacter Infections - microbiology | Helicobacter pylori
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13. Full Text DNA transfer in the gastric pathogen Helicobacter pylori
by Fernandez-Gonzalez, Esther and Backert, Steffen
Journal of Gastroenterology, ISSN 0944-1174, 4/2014, Volume 49, Issue 4, pp. 594 - 604
The gastric pathogen Helicobacter pylori is one of the most genetically diverse bacteria. Recombination and DNA transfer contribute to its genetic variability... 
Recombination | Competence | Genetic variability | VirB/D | Virulence | Host adaptation | Cag | Phage transduction | Pilus | Tyrosine recombinase | Plasmid mobilization | Origin of transfer | Pathogenicity island | ADR | Relaxase | Medicine & Public Health | Colorectal Surgery | Hepatology | Gastroenterology | Abdominal Surgery | Conjugation | Surgical Oncology | DNA transfer | Type IV secretion system | HUMAN-CELLS | COMPLETE GENOME SEQUENCE | IV SECRETION SYSTEMS | NATURAL TRANSFORMATION COMPETENCE | CAMPYLOBACTER-JEJUNI | ANTIBIOTIC-RESISTANCE | CONJUGATIVE PLASMIDS | GENETIC DIVERSITY | GRAM-POSITIVE BACTERIA | SMALL CRYPTIC PLASMID | GASTROENTEROLOGY & HEPATOLOGY | Conjugation, Genetic | Bacterial Secretion Systems - genetics | Transformation, Bacterial | Recombination, Genetic | Humans | Bacterial Proteins - genetics | Helicobacter pylori - genetics | Helicobacter pylori - pathogenicity | Plasmids - genetics | Gene Transfer, Horizontal | Helicobacter Infections - genetics | Helicobacter infections | Helicobacter pylori | Genes | DNA
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14. Erratum to: Type IV Secretion in Gram-Negative and Gram-Positive Bacteria
by Backert, Steffen and Grohmann, Elisabeth
Current topics in microbiology and immunology, ISSN 0070-217X, 01/2017, Volume 413, p. E1
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15. Full Text Type IV secretion in Gram‐negative and Gram‐positive bacteria
by Grohmann, Elisabeth and Christie, Peter J and Waksman, Gabriel and Backert, Steffen
Molecular Microbiology, ISSN 0950-382X, 02/2018, Volume 107, Issue 4, pp. 455 - 471
Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the entire cell envelope in Gram‐negative and Gram‐positive bacteria. They... 
LEGIONELLA-PNEUMOPHILA | NATURAL TRANSFORMATION | CONJUGATIVE ELEMENT ICEBS1 | DNA TRANSFER | BRUCELLA-ABORTUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROBIOLOGY | PEPTIDOGLYCAN HYDROLASE | HELICOBACTER-PYLORI | CORE COMPLEX | COXIELLA-BURNETII | CAG PATHOGENICITY ISLAND | Gram-Positive Bacteria - genetics | Gram-Positive Bacteria - metabolism | Host-Pathogen Interactions | Animals | DNA, Bacterial - metabolism | Plasmids | DNA, Single-Stranded - metabolism | Humans | Gram-Negative Bacteria - genetics | Gram-Negative Bacteria - metabolism | Type IV Secretion Systems - chemistry | Type IV Secretion Systems - metabolism | Physiological aspects | Bacteria | Bacterial infections | Pilin | Stoichiometry | Secretion | Gram-positive bacteria | Legionella pneumophila | Phospholipids | Molecular modelling | Helicobacter pylori | E coli | Deoxyribonucleic acid--DNA | Structure-function relationships | anti-apoptosis | VirD4 | signaling | core structure | transfer genes | apoptosis | VirB | T-DNA | conjugation | CEACAM | relaxosome | relaxase | oriT | killer toxin | integrin | vacuole | signal transduction | T4SS | ATPase | transfer DNA | CagA | Dot | intracellular trafficking | pilus | type IV secretion | T4CP | mating pair formation | coupling protein | Icm | NTPase | 3D-structure
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16. Full Text Type IV Secretion in Gram-Negative and Gram-Positive Bacteria
by Backert, Steffen and Grohmann, Elisabeth
03/2018, Current Topics in Microbiology and Immunology, ISBN 3319752405, Volume 413, 364
Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver... 
Gram-negative bacteria | Medical Microbiology | Infectious Diseases | Biomedicine | Immunology | Gastroenterology
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17. Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system
by Backert, Steffen and Tegtmeyer, Nicole and Fischer, Wolfgang
Future Microbiology, ISSN 1746-0913, 06/2015, Volume 10, Issue 6, pp. 955 - 965
Many Gram-negative pathogens harbor type IV secretion systems (T4SS) that translocate bacterial virulence factors into host cells to hijack cellular processes.... 
signaling | T4SS | CagA | type IV secretion | tyrosine kinases | CagY | β-catenin | gastric disease | Helicobacter pylori | VirB proteins | MARK2/PAR1b kinase | cagPAI | EGF receptor | c-Met | CagL | integrin | GTPase | cortactin | TRANSLOCATION | ONCOPROTEIN | ACTIVATION | PROTEIN | CELL SCATTERING | PHOSPHORYLATION | KINASE | MICROBIOLOGY | beta-catenin | COMPLEX | CRYSTAL-STRUCTURE | ADHESION | Helicobacter pylori - chemistry | Humans | Protein Multimerization | Helicobacter pylori - genetics | Type IV Secretion Systems - genetics | Genomic Islands | Type IV Secretion Systems - chemistry | Protein Transport | Bacterial Adhesion | Epithelial Cells - physiology | Helicobacter pylori - metabolism | Models, Biological | Epithelial Cells - microbiology | Bacterial Proteins - metabolism | Protein Conformation | Virulence Factors - metabolism | Antigens, Bacterial - metabolism | Type IV Secretion Systems - metabolism
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18. Full Text Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori
by Backert, Steffen and Clyne, Marguerite and Tegtmeyer, Nicole
Cell Communication and Signaling, ISSN 1478-811X, 2011, Volume 9, Issue 1, pp. 28 - 28
Helicobacter pylori is a highly successful pathogen uniquely adapted to colonize humans. Gastric infections with this bacterium can induce pathology ranging... 
adhesin | receptor | Helicobacter pylori | adherence | type IV secretion | integrin | signalling | MEMBRANE PROTEIN EXPRESSION | TYROSINE PHOSPHORYLATION | CRYSTAL-STRUCTURE | VIRULENCE FACTOR | FUNCTIONAL-CHARACTERIZATION | PATHOGENICITY ISLAND | CELL BIOLOGY | HOST-CELL | IV SECRETION SYSTEM | BABA ADHESIN | EXPERIMENTAL-INFECTION | Epithelial cells | Cell adhesion | Physiological aspects | Development and progression | Genetic aspects | Research | Stomach cancer | Proteins | Studies | Science | Bacteria | Pathogens | Adhesins | 3-Aminobutyric acid | Secretion | Chronic infection | Cell membranes | Cell interactions | Gastritis | phosphatidylserine | Molecular modelling | Reviews | peptic ulcers | pathogenicity islands | Blood groups | Gastric cancer | Colonization | Integrins
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19. Full Text Helicobacter pyloriinfection of AZ-521 cells reveals a type IV secretion defect and VacA-independent CagA phosphorylation
by Tegtmeyer, Nicole and Backert, Steffen
Disease Models & Mechanisms, ISSN 1754-8403, 12/2017, Volume 10, Issue 12, pp. 1539 - 1540
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20. Full Text How Helicobacter pylori infection controls gastric acid secretion
by Smolka, Adam J and Backert, Steffen
Journal of Gastroenterology, ISSN 0944-1174, 6/2012, Volume 47, Issue 6, pp. 609 - 618
Infection of the human stomach mucosa by Helicobacter pylori induces strong inflammatory responses and a transitory hypochlorhydria which can progress in ~2 %... 
Transcription factor NF-κB | HB-EGF | HKα-ATPase | cag pathogenicity island | Oncology | Internal Medicine | Gastric adenocarcinoma | EGFR | ADAM17 | ERK1/2 | Hypochlorhydria | Medicine & Public Health | Helicobacter pylori | Colorectal Surgery | Hepatology | Gastroenterology | Parietal cells | Surgical Oncology | Integrin α 5 β 1 | Type IV secretion system | Integrin α | Transcription factor NF-jB | Cag pathogenicity island | Transcription factor NF-kappa B | ALPHA-SUBUNIT | HK alpha-ATPase | IV SECRETION | SERUM RESPONSE ELEMENT | BINDING-PROTEINS | CAGA PROTEIN | Integrin a5b1 | HUMAN PARIETAL-CELLS | EPITHELIAL-CELLS | MESSENGER-RNA | GASTROENTEROLOGY & HEPATOLOGY | NF-KAPPA-B | SUBUNIT GENE-EXPRESSION | Evidence-Based Medicine - methods | Achlorhydria - microbiology | Humans | Helicobacter Infections - complications | H(+)-K(+)-Exchanging ATPase - genetics | Helicobacter Infections - genetics | Gastric Acid - secretion | Animals | Proton Pumps - physiology | Helicobacter Infections - metabolism | Transcription, Genetic | Disease Models, Animal | Enzymes | Epidermal growth factor | Gene mutations | Helicobacter infections | Universities and colleges | Gene expression | Health aspects | Adenosine triphosphatase | Infection control | Integrins | Adenocarcinoma | Transcription factors | Epithelial cells | Mucosa | Signal transduction | Triphosphatase | Metalloproteinase | Translocation | Stomach | Dysplasia | Epidermal growth factor receptors | Secretion | Extracellular signal-regulated kinase | Inflammation | Promoters | virulence factors | Gastritis | Infection | NF- Kappa B protein | Reviews | Biopsy | pathogenicity islands | Point mutation
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