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Annual Review of Genomics and Human Genetics, ISSN 1527-8204, 01/2018, Volume 19, p. 177
Primary microcephaly (MCPH, for “microcephaly primary hereditary”) is a disorder of brain development that results in a head circumference more than 3 standard... 
Wnt protein | Cortex | Intracellular signalling | Evolutionary genetics | Cytokinesis | Microcephaly | Neurodevelopmental disorders | Autophagy | DNA repair | Progenitor cells | DNA biosynthesis | Microencephaly | Molecular modelling | Neural stem cells | Polarity | Phagocytosis
Journal Article
Developmental Cell, ISSN 1534-5807, 02/2015, Volume 32, Issue 4, pp. 423 - 434
Journal Article
Cell, ISSN 0092-8674, 10/2016, Volume 167, Issue 2, pp. 341 - 354.e12
Journal Article
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 05/2016, p. ddw115
Journal Article
Science, ISSN 0036-8075, 2014, Volume 343, Issue 6172, pp. 764 - 768
Journal Article
Neuron, ISSN 0896-6273, 11/2016, Volume 92, Issue 4, pp. 813 - 828
Journal Article
Neuron, ISSN 0896-6273, 07/2005, Volume 47, Issue 1, pp. 29 - 41
We present evidence for a specific role of p53 in the mitochondria- associated cellular dysfunction and behavioral abnormalities of Huntington's disease (HD).... 
NUCLEAR-LOCALIZATION | N-TERMINAL FRAGMENTS | PREPULSE INHIBITION | MUTANT HUNTINGTIN | TRANSCRIPTIONAL ACTIVATOR | STRIATAL CELLS | AMYOTROPHIC-LATERAL-SCLEROSIS | INTRANUCLEAR INCLUSIONS | TRANSGENIC MOUSE MODEL | POLYGLUTAMINE PATHOGENESIS | NEUROSCIENCES | Neurons - pathology | Apoptosis - drug effects | Electron Transport - genetics | Humans | Huntington Disease - pathology | Huntington Disease - psychology | Tumor Suppressor Protein p53 - physiology | Nerve Tissue Proteins - toxicity | Gene Deletion | Plasmids - genetics | Densitometry | Electron Transport - physiology | Cell Survival - physiology | Nerve Tissue Proteins - physiology | Retinal Degeneration - genetics | Drosophila | Mice, Inbred C57BL | Behavior, Animal - physiology | Genes, Reporter - genetics | Mice, Transgenic | Behavior - physiology | Escape Reaction - physiology | Nuclear Proteins - toxicity | Huntingtin Protein | Blotting, Northern | Transcription, Genetic - physiology | Animals | Mice | Nuclear Proteins - physiology | Mitochondria - physiology | Retinal Degeneration - pathology | Medical colleges | Neurosciences | RNA | Huntington's chorea | Neurons | Oncology, Experimental | Analysis | Research | Tumor proteins | Cancer | Huntingtons disease | Genes | Amino acids | Cytotoxicity | Variance analysis | Patients | Proteins | Pathology | Mitochondria | Neurotoxicity | Plasmids | Rodents | Monitoring systems
Journal Article
NATURE, ISSN 0028-0836, 04/2018, Volume 556, Issue 7701, pp. 370 - 370
The human cerebral cortex is distinguished by its large size and abundant gyrification, or folding. However, the evolutionary mechanisms that drive cortical... 
NEURAL PROGENITORS | CELL-DIVISION | NEOCORTEX | CORTEX | OUTER SUBVENTRICULAR ZONE | MULTIDISCIPLINARY SCIENCES | NEUROGENESIS | MUSTELA-PUTORIUS | MUTATIONS | RADIAL GLIA | BRAIN | Microcephaly - genetics | Ferrets - anatomy & histology | Humans | Nerve Tissue Proteins - deficiency | Cerebral Cortex - pathology | Male | Cerebral Cortex - metabolism | Nerve Tissue Proteins - chemistry | Gene Expression Regulation, Developmental | Gene Deletion | Microcephaly - pathology | Germ-Line Mutation | Female | Transcription, Genetic | Calmodulin-Binding Proteins - deficiency | Cerebral Cortex - anatomy & histology | Ferrets - genetics | Disease Models, Animal | Amino Acid Sequence | Organ Size | Calmodulin-Binding Proteins - metabolism | Gene Knockout Techniques | Nerve Tissue Proteins - genetics | Neural Stem Cells - pathology | Gene Editing | Centrosome - metabolism | Biological Evolution | Nerve Tissue Proteins - metabolism | Animals | Mice | Neural Stem Cells - metabolism | Genetically modified animals | Physiological aspects | Cerebral cortex | Genetic aspects | Ferrets | Brain | Genes | Biological evolution | Radial glial cells | Homology | Genomes | Glial cells | Microcephaly | Biodiversity | Subventricular zone | Neurogenesis | Neuronal-glial interactions | Proteins | Species diversity | Rodents | Primates | Evolution | Genetics | Expansion | Fetuses | Cortex | Amino acid sequence | Gene expression | Progenitor cells | Microencephaly | Cells (biology) | Weight reduction | Neural stem cells | Mutation | Ventricle | Surface area
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2006, Volume 103, Issue 10, pp. 3887 - 3889
Journal Article
Science, ISSN 0036-8075, 10/2013, Volume 342, Issue 6155, pp. 200 - 201
  The human cerebral cortex defines us as who we are. Its development and function underlie complex human cognitive behavior, while its malfunction or... 
Brain | Nervous system diseases | Organoids | Disease models | Neurons | Totipotent stem cells | Humans | Stem cells | PERSPECTIVES | Pluripotent stem cells | Cells | MULTIDISCIPLINARY SCIENCES | Developmental biology | Neurosciences | Human | Cerebral cortex | Animals | Mathematical models | Human behavior | Diseases
Journal Article
Journal of Ocean Engineering and Technology, ISSN 1225-0767, 10/2012, Volume 26, Issue 5, pp. 87 - 93
Journal Article