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Nature Medicine, ISSN 1078-8956, 11/2015, Volume 21, Issue 11, pp. 1326 - 1331
Mechanical allodynia, induced by normally innocuous low-threshold mechanical stimulation, represents a cardinal feature of neuropathic pain. Blockade or... 
MEDICINE, RESEARCH & EXPERIMENTAL | FLAGELLIN | NOCICEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TACTILE ALLODYNIA | INNATE | RATS | SPINAL-CORD | NERVE INJURY | CELL BIOLOGY | TOLL-LIKE RECEPTOR-5 | ITCH | PRIMARY SENSORY NEURONS | Lidocaine - pharmacology | Neuralgia - genetics | Capsaicin - pharmacology | Toll-Like Receptor 5 - genetics | Humans | Middle Aged | Neuralgia - metabolism | Male | Neurons - cytology | Ganglia, Spinal - cytology | Anesthetics, Local - pharmacology | Antineoplastic Agents - toxicity | Sensory System Agents - pharmacology | Flagellin - pharmacology | Paclitaxel - toxicity | Neuralgia - etiology | Nerve Fibers, Unmyelinated - drug effects | Adult | Female | Neurons - metabolism | Neurons - drug effects | Nerve Fibers, Myelinated - metabolism | Peripheral Nerve Injuries - complications | Hyperalgesia - metabolism | Nerve Fibers, Myelinated - drug effects | Mice, Knockout | Lidocaine - analogs & derivatives | Animals | Hyperalgesia - genetics | Hyperalgesia - etiology | Aged | Mice | Ganglia, Spinal - drug effects | Neurofilament Proteins - metabolism | Diabetic Neuropathies - complications | Ganglia, Spinal - metabolism | Genetically modified mice | Care and treatment | Pain | Dorsal root ganglia | Management | Research | TLR5 | Chronic pain | Pharmacology | Neurological disorders | Pain management | Immune system
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4939 - 8
Molecular cloning is an essential technique in molecular biology and biochemistry, but it is frequently laborious when adequate restriction enzyme recognition... 
CAS9 | RNA | GUIDE | MULTIDISCIPLINARY SCIENCES | CRISPR | Enzymes | Adenosine | Plasmids | Cloning | DNA damage | Adenine | Endonuclease | Deoxyribonucleic acid--DNA | Guanine
Journal Article
Bioinformatics, ISSN 1367-4803, 03/2018, Volume 34, Issue 6, pp. 1077 - 1079
Journal Article
Bioinformatics, ISSN 1367-4803, 07/2015, Volume 31, Issue 24, pp. 4014 - 4016
Journal Article
Nature Communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, p. 13350
The type II CRISPR-associated protein Cas9 recognizes and cleaves target DNA with the help of two guide RNAs (gRNAs; tracrRNA and crRNA). However, the detailed... 
SINGLE-MOLECULE FRET | IMMUNITY | COMPLEX | SPECIFICITY | MULTIDISCIPLINARY SCIENCES | RESISTANCE | CRISPR-CAS9 | CLEAVAGE | REPEATS | TARGET DNA RECOGNITION | PROKARYOTES
Journal Article
BMB Reports, ISSN 1976-6696, 2016, Volume 49, Issue 4, p. 201
The CRISPR-Cas system has emerged as a fascinating and important genome editing tool. It is now widely used in biology, biotechnology, and biomedical research... 
Type 1 CRISPR | Type 2 CRISPR | CRISPR-Cas system | Crystal structure | Single molecule
Journal Article
by Kim, HS and Jeong, YK and Hur, JK and Kim, JS and Bae, S
NATURE BIOTECHNOLOGY, ISSN 1087-0156, 10/2019, Volume 37, Issue 10, pp. 1145 - 1145
Adenine base editors comprise an adenosine deaminase, evolved in vitro, and a Cas9 nickase. Here, we show that in addition to converting adenine to guanine,... 
TARGET | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENOMIC DNA | Adenosine | Editors | Thymine | Editing | Adenine | Cytosine | Adenosine deaminase | Guanine
Journal Article
Bioinformatics, ISSN 1367-4803, 01/2017, Volume 33, Issue 2, pp. 286 - 288
Journal Article
Analytical Chemistry, ISSN 0003-2700, 12/2016, Volume 88, Issue 23, pp. 11288 - 11292
Surface enhanced Raman scattering (SERS) is highly useful for sensitive analytical sensing; however, its practical availability for detecting a point mutation... 
NANOPARTICLES | CHEMISTRY, ANALYTICAL | CHIP | GENE | DNA | APTAMER | HYBRIDIZATION | EXACERBATION | LASIK | PROBES | Point Mutation | Transforming Growth Factor beta - genetics | Extracellular Matrix Proteins - genetics | Humans | Surface Properties | Corneal Dystrophies, Hereditary - genetics | Spectrum Analysis, Raman | Usage | Care and treatment | Raman effect | Corneal diseases | Research | Gene expression
Journal Article