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1. Full Text Dr Patrick Baeuerle, MPMCapital, talks with young scientists
by Antonopoulos, Alexios and Psarros, Konstantinos and Abdesselem, Mouna and Szolc, Piotr and Baeuerle, Patrick
Cardiovascular research, ISSN 0008-6363, 10/2017, Volume 113, Issue 12, pp. E42 - E42
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology
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2. Full Text Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response
by Baeuerle, Patrick A and Ding, Jian and Patel, Ekta and Thorausch, Niko and Horton, Holly and Gierut, Jessica and Scarfo, Irene and Choudhary, Rashmi and Kiner, Olga and Krishnamurthy, Janani and Le, Bonnie and Morath, Anna and Baldeyiano, G. Christian and Quinn, Justin and Tayares, Patrick and Wei, Qi and Weiler, Solly and Maus, Marcela and Getts, Daniel and Schamel, Wolfgang W and Hofmeister, Robert
Nature communications, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2087 - 2087
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Recombinant Fusion Proteins - immunology | Immunotherapy, Adoptive - methods | Antigens, Neoplasm - immunology | Humans | Treatment Outcome | Receptors, Artificial - immunology | Receptors, Artificial - genetics | Xenograft Model Antitumor Assays | Neoplasms - therapy | Animals | Single-Chain Antibodies - genetics | Neoplasms - immunology | Cell Line, Tumor | Protein Domains | Recombinant Fusion Proteins - genetics | Female | Mice, Inbred NOD | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Primary Cell Culture | Single-Chain Antibodies - immunology | Antigens, CD19 - immunology | Antigens | CD19 antigen | Surface antigens | Tumor cells | Xenotransplantation | T cell receptors | Lymphocytes T | Cell fusion | Anticancer properties | T-cell receptor | Chimeric antigen receptors | Receptors | Antitumor agents | Lymphocytes B | Lymphocytes | Antigen (tumor-associated) | Xenografts | Histocompatibility antigen HLA | Solid tumors | Tumors | Index Medicus
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3. Full Text Immunomodulatory therapy of cancer with T cell-engaging BiTE antibody blinatumomab
by Nagorsen, Dirk and Baeuerle, Patrick A
Experimental cell research, ISSN 0014-4827, 2011, Volume 317, Issue 9, pp. 1255 - 1260
Antibody | Bispecific | BiTE | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Antibodies, Bispecific - therapeutic use | Immunomodulation | Leukemia, Lymphoid - therapy | Humans | Lymphoma, B-Cell - therapy | Lymphoma, B-Cell - immunology | T-Lymphocytes - immunology | Clinical Trials as Topic | Antibodies, Bispecific - immunology | Leukemia, Lymphoid - immunology | Viral antibodies | Care and treatment | Leukemia | Antibodies | Non-Hodgkin's lymphomas | T cells | Health aspects | Cancer | Immunotherapy | Cells | CD19 antigen | Tumor cells | Bites | Clinical trials | Cytotoxicity | CD3 antigen | Lymphocytes T | Lymphatic leukemia | Non-Hodgkin's lymphoma | Side effects | Lymphocytes B | Remission | Bispecific antibodies | Index Medicus
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4. Full Text Antioxidant and redox regulation of genes
by Baeuerle, P. A. 1957- (Patrick Alexander) and Sen, Chandan K and Sies, H. 1942- (Helmut)
2000, ISBN 0126366705, 591
Antioxidants | Oxygen | Oxidation-Reduction | Gene Expression Regulation | physiology | Oxidation-reduction reaction | Genetic regulation | xygen | Physiological effect | Active oxygen | Pathophysiology | Cellular signal transduction | Active oxygen in the body
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5. Full Text Bispecific T-cell engaging antibodies for cancer therapy
by Baeuerle, Patrick A and Reinhardt, Carsten
Cancer research (Chicago, Ill.), ISSN 0008-5472, 06/2009, Volume 69, Issue 12, pp. 4941 - 4944
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Antibodies, Bispecific - therapeutic use | T-Lymphocytes - immunology | Neoplasms - therapy | Antibodies, Bispecific - immunology | Humans | Index Medicus
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6. Full Text Targeting T cells to tumor cells using bispecific antibodies
by Frankel, Stanley R and Baeuerle, Patrick A
Current opinion in chemical biology, ISSN 1367-5931, 06/2013, Volume 17, Issue 3, pp. 385 - 392
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Antibodies, Bispecific - therapeutic use | Animals | Neoplasms - immunology | Humans | T-Lymphocytes - immunology | Antibodies, Bispecific - immunology | Neoplasms - drug therapy | Viral antibodies | Antibodies | T cells | Immunotherapy | Tumors | Index Medicus
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7. Full Text Blinatumomab: A historical perspective
by Nagorsen, Dirk and Kufer, Peter and Baeuerle, Patrick A and Bargou, Ralf
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 12/2012, Volume 136, Issue 3, pp. 334 - 342
Bispecific antibody | Lymphoma | Leukemia | BiTE | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Antibodies, Bispecific - therapeutic use | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Animals | Lymphoma, Large B-Cell, Diffuse - drug therapy | Antibodies, Bispecific - administration & dosage | Humans | Lymphoma, Mantle-Cell - drug therapy | Antibodies, Bispecific - chemistry | Clinical Trials as Topic | MHC antibodies | Immunoglobulin G | Monoclonal antibodies | Transplantation | Non-Hodgkin's lymphomas | Hematopoietic stem cells | Index Medicus
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8. Clinical experience with gene therapy and bispecific antibodies for T cell-based therapy of cancer
by Baeuerle, Patrick A and Itin, Christian
Current pharmaceutical biotechnology, ISSN 1389-2010, 06/2012, Volume 13, Issue 8, pp. 1399 - 1408
Single-chain antibody | Catumaxomab | CD3 | T cell receptor | Chimeric antigen receptor | T-body | Tumor-associated antigen | Blinatumomab | Cancer therapy | T cell | Bispecific antibody | Zeta chain | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Antibodies, Bispecific - therapeutic use | Neoplasms - therapy | Animals | Recombinant Proteins - immunology | Neoplasms - immunology | Humans | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Recombinant Proteins - genetics | Tumor cells | Adjuvants | Cytotoxicity | Data processing | Lymphocytes T | Vaccines | T-cell receptor | Reviews | Fusion protein | Gene therapy | Bispecific antibodies | Cancer | Pharmaceuticals
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9. Full Text The emerging role of EpCAM in cancer and stem cell signaling
by Munz, Markus and Baeuerle, Patrick A and Gires, Olivier
Cancer research (Chicago, Ill.), ISSN 0008-5472, 07/2009, Volume 69, Issue 14, pp. 5627 - 5629
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Neoplasms - metabolism | Cell Adhesion Molecules - physiology | Signal Transduction | Humans | Stem Cells - metabolism | Cell Adhesion Molecules - metabolism | beta Catenin - metabolism | Epithelial Cell Adhesion Molecule | Animals | Models, Biological | Antigens, Neoplasm - physiology | Antigens, Neoplasm - metabolism | Protein Binding | Stem Cells - physiology | Neoplasms - physiopathology | Index Medicus
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10. Full Text On the abundance of EpCAM on cancer stem cells
by Klein, Christoph A and Gires, Olivier and Baeuerle, Patrick A
Nature reviews. Cancer, ISSN 1474-175X, 02/2009, Volume 9, Issue 2, pp. 143 - 143
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms - metabolism | Epithelial Cells - metabolism | Neoplastic Stem Cells - metabolism | Cell Adhesion Molecules - metabolism | Humans | Control | Research | Health aspects | Stem cells | Cell adhesion molecules | Tumors | Index Medicus
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11. Full Text Nuclear signalling by tumour-associated antigen EpCAM
by Maetzel, Dorothea and Denzel, Sabine and Mack, Brigitte and Canis, Martin and Went, Philip and Benk, Michael and Kieu, Cuong and Papior, Peer and Baeuerle, Patrick A and Munz, Markus and Gires, Olivier
Nature cell biology, ISSN 1465-7392, 2009, Volume 11, Issue 2, pp. 162 - 171
Life Sciences & Biomedicine | Science & Technology | Cell Biology | ADAM17 Protein | NIH 3T3 Cells | Cell Adhesion Molecules - genetics | Colonic Neoplasms - genetics | Cell Proliferation | Active Transport, Cell Nucleus - physiology | Homeodomain Proteins - metabolism | Humans | Lymphoid Enhancer-Binding Factor 1 - genetics | Male | Presenilin-2 - metabolism | Cell Membrane - genetics | Colonic Neoplasms - metabolism | Epithelial Cell Adhesion Molecule | Cell Nucleus - metabolism | Cell Transformation, Neoplastic - genetics | Muscle Proteins - metabolism | Antigens, Neoplasm - metabolism | Cell Membrane - metabolism | Protein Structure, Tertiary | Antigens, Neoplasm - genetics | Transcription Factors - genetics | Cell Adhesion Molecules - metabolism | Cell Transformation, Neoplastic - metabolism | Lymphoid Enhancer-Binding Factor 1 - metabolism | beta Catenin - metabolism | Homeodomain Proteins - genetics | beta Catenin - genetics | Muscle Proteins - genetics | Transcription Factors - metabolism | ADAM Proteins - metabolism | Animals | Cell Nucleus - genetics | Mitosis - physiology | Carcinoma - genetics | LIM-Homeodomain Proteins | Signal Transduction - physiology | Mice | Carcinoma - metabolism | Tumor antigens | Physiological aspects | Genetic aspects | Research | Health aspects | Cell adhesion molecules | Membrane proteins | Index Medicus
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12. Full Text Targeted Therapy With the T-Cell–Engaging Antibody Blinatumomab of Chemotherapy-Refractory Minimal Residual Disease in B-Lineage Acute Lymphoblastic Leukemia Patients Results in High Response Rate and Prolonged Leukemia-Free Survival
by Max S. Topp and Peter Kufer and Nicola Gökbuget and Mariele Goebeler and Matthias Klinger and Svenja Neumann and Heinz-A. Horst and Thorsten Raff and Andreas Viardot and Mathias Schmid and Matthias Stelljes and Markus Schaich and Evelyn Degenhard and Rudolf Köhne-Volland and Monika Brüggemann and Oliver Ottmann and Heike Pfeifer and Thomas Burmeister and Dirk Nagorsen and Margit Schmidt and Ralf Lutterbuese and Carsten Reinhardt and Patrick A. Baeuerle and Michael Kneba and Hermann Einsele and Gert Riethmüller and Dieter Hoelzer and Gerhard Zugmaier and Ralf C. Bargou
Journal of clinical oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 18, pp. 2493 - 2498
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Tumors | Antibody Specificity | Immunotherapy - methods | Humans | Middle Aged | Antibodies, Bispecific - pharmacokinetics | Drug Resistance, Neoplasm | Male | Molecular Targeted Therapy | Drug Delivery Systems | Neoplasm, Residual | Young Adult | T-Lymphocytes, Cytotoxic - drug effects | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Agammaglobulinemia - chemically induced | T-Cell Antigen Receptor Specificity - immunology | Aged, 80 and over | T-Cell Antigen Receptor Specificity - drug effects | Adult | Female | B-Lymphocytes - pathology | Antigens, CD19 - immunology | T-Lymphocytes, Cytotoxic - immunology | Antigens, Neoplasm - immunology | Lymphocyte Activation | Kaplan-Meier Estimate | Combined Modality Therapy | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - therapy | Remission Induction | Antibodies, Bispecific - therapeutic use | Cell Lineage | Disease-Free Survival | Antibodies, Bispecific - adverse effects | B-Lymphocytes - immunology | Bone Marrow - pathology | CD3 Complex - immunology | Aged | Lymphopenia - chemically induced | Index Medicus
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13. Full Text Expression and function of epithelial cell adhesion molecule EpCAM: where are we after 40 years?
by Gires, Olivier and Pan, Min and Schinke, Henrik and Canis, Martin and Baeuerle, Patrick A
Cancer and metastasis reviews, ISSN 0167-7659, 09/2020, Volume 39, Issue 3, pp. 969 - 987
Life Sciences & Biomedicine | Oncology | Science & Technology | Medical colleges | Antigens | Epidermal growth factor | Proteolysis | Colorectal cancer | Stem cells | Metastasis | Cell proliferation | Wnt protein | Epidermal growth factor receptors | Mesenchyme | Tumor cells | Epithelial cells | Colorectal carcinoma | Intracellular signalling | Raf protein | E-cadherin | Cell adhesion molecules | Cell adhesion & migration | Metastases | CD44 antigen | Intracellular | Cell migration | Index Medicus | Carcinoma | EpCAM | Regulated intramembrane proteolysis | Non-Thematic Review | Epithelial-to-mesenchymal transition | Liquid biopsy
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