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by Roncaglioni, Maria Carla and Avanzini, Fausto and Barlera, Simona and Marzona, Irene and Milani, Valentina and Tombesi, Massimo and Caimi, Vittorio and Longoni, Paolo and Silletta, Maria Giuseppina and Tognoni, Gianni and Marchioli, Roberto and Nicolis, E.B and Casola, C and Massa, E and Marrocco, W and Micalella, M and Franzosi, M.G and Geraci, E and Giansiracusa, N and Rocchetti, L and Decarli, A and Satolli, R and Alli, C and Beghi, E and Bertele', V and Volpi, A and Baviera, M and Monesi, L and Pangrazzi, I and Nicolis, E and Clerici, F and Palumbo, A and Sgaroni, G and Pioggiarella, R and Scarano, M and Marfisi, R.M and Flamminio, A and Macino, L and Ferri, B and Pera, C and Polidoro, A and Abbatino, D and Acquati, M and Addorisio, G and Adinolfi, D and Adreani, L and Agistri, M.R and Agneta, A and Agnolio, M.L and Agostini, N and Agostino, G and Airò, A and Alaimo, N and Albano, M and Albano, N and Alecci, G and Alemanno, S and Alexanian, A and Alfarano, M and Alfè, L and Alonzo, N and Alvino, S and Ancora, A and Andiloro, S and Andreatta, E and Angeli, S and Angiari, F and Angilletti, V and Annicchiarico, C and Anzivino, M and Aprea, R and Aprile, A and Aprile, E and Aprile, I and Aprile, L and Armellani, V and Arnetoli, M and Aronica, A and Autiero, V and Bacca, G and Baccalaro, A.M and Bacci, M and Baglio, G and Bagnani, M and Baiano, A and Baldari, A and Ballarini, L and Banchi, G and Bandera, R and Bandini, F and Baratella, M and Barbieri, A and Barbieri Vita, A and Bardi, M and Barlocchi, M and Baron, P and Bartoli, M and Basile, A and Basile, F and Basile, S and ... and The Risk and Prevention Study Collaborative Group and Risk Prevention Study Collaborativ and Risk and Prevention Study Collaborative Group
The New England Journal of Medicine, ISSN 0028-4793, 05/2013, Volume 368, Issue 19, pp. 1800 - 1808
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 2014, Volume 20, Issue 8, pp. 904 - 910
Individuals with neurofibromatosis type-1 (NF1) can manifest focal skeletal dysplasias that remain extremely difficult to treat. NF1 is caused by mutations in... 
Biochemistry, Genetics and Molecular Biology(all) | MEDICINE, RESEARCH & EXPERIMENTAL | ENZYME-REPLACEMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | TIBIAL PSEUDOARTHROSIS | DISTINCT ROLES | CONGENITAL PSEUDOARTHROSIS | ALKALINE-PHOSPHATASE ACTIVITY | CELL BIOLOGY | SUPPRESSES OSTEOBLAST DIFFERENTIATION | MATRIX MINERALIZATION | INORGANIC PYROPHOSPHATE | NF1 | MORPHOGENETIC PROTEIN-7 | Diphosphates - metabolism | Phosphoric Diester Hydrolases - biosynthesis | Pyrophosphatases - biosynthesis | Humans | Recombinant Fusion Proteins - therapeutic use | Pyrophosphatases - genetics | Child, Preschool | Infant | Bone Diseases, Developmental - genetics | Durapatite - metabolism | Bone Morphogenetic Protein 2 - metabolism | Phosphate Transport Proteins - genetics | Child | Osteogenesis - genetics | Disease Models, Animal | Bone Morphogenetic Protein 2 - genetics | Bone Development - drug effects | Calcification, Physiologic - drug effects | Osteoblasts - enzymology | Mice, Inbred C57BL | Cells, Cultured | Immunoglobulin G - therapeutic use | Phosphate Transport Proteins - biosynthesis | Phosphoric Diester Hydrolases - genetics | Transcription Factors - genetics | Alkaline Phosphatase - therapeutic use | Collagen Type II - genetics | Mice, Knockout | Collagen Type I - biosynthesis | Animals | Alkaline Phosphatase - biosynthesis | Neurofibromatosis 1 - drug therapy | Adolescent | Sp7 Transcription Factor | Mice | Neurofibromin 1 - genetics | Mitogen-Activated Protein Kinases - metabolism | mesenchymal stem cell | Neurofibromatosis type I | neurofibromin | pyrophosphate | Enpp1 | osteoblast | bone mineralization | Ank | PC1
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 03/2018, Volume 217, Issue 3, pp. 1129 - 1142
Exosomes are small endosome-derived extracellular vesicles implicated in cell-cell communication and are secreted by living cells when multivesicular bodies... 
Cell Biology | CD63 | LYSOSOMES | EXTRACELLULAR VESICLES | PERMEABILITY | PHOSPHORYLATION | MULTIVESICULAR ENDOSOMES | MEMBRANES | RECEPTOR | RELEASE | PROTEINS | CELL BIOLOGY | Life Sciences | Cellular Biology | Cell Behavior
Journal Article
Journal Article