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NeuroMolecular Medicine, ISSN 1535-1084, 3/2019, Volume 21, Issue 1, pp. 1 - 11
The nuclear factor erythroid-derived 2-related factor 2 (NFE2L2/NRF2) is a master transcription factor that regulates oxidative stress-related genes containing... 
Neurology | Oxidative stress | Neurosciences | Biomedicine | NRF2 activator | NRF2 | Alzheimer’s disease | ROS | Internal Medicine | Neurodegenerative disease | Amyloid-β | Animal models | Parkinson's disease | Disease | Neurodegenerative diseases | Therapeutic applications | Homeostasis | Amyotrophic lateral sclerosis | Risk factors | Antioxidants | Localization | Alzheimer's disease | Movement disorders
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2019, Volume 116, Issue 25, pp. 12516 - 12523
BACE1 is the rate-limiting enzyme for amyloid-β peptides (Aβ) generation, a key event in the pathogenesis of Alzheimer’s disease (AD). By an unknown mechanism,... 
BACE1 | Alzheimer’s disease | NRF2 | 3xTg-AD mice | 5xFAD mice | Antioxidants | Animal models | b-Site APP cleaving enzyme 1 | Depletion | Peptides | Pathogenesis | Cognitive ability | Antisense RNA | Activation | Amyloid | Regulatory sequences | Alzheimer's disease | Biological Sciences | PNAS Plus
Journal Article
Annals of Neurology, ISSN 0364-5134, 03/2015, Volume 77, Issue 3, pp. 504 - 516
Journal Article
by Bahn, G and Jo, DG
NEUROMOLECULAR MEDICINE, ISSN 1535-1084, 03/2019, Volume 21, Issue 1, pp. 1 - 11
Journal Article
Scientific Reports, ISSN 2045-2322, 01/2016, Volume 6, Issue 1, p. 19377
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2018, Volume 504, Issue 4, pp. 903 - 908
Activating transcription factor 3 ( ) has been previously demonstrated to impact obesity and metabolism. However, a metabolic role of Atf3 in mice remains... 
Obesity | Adipocyte | Metabolic diseases | Sulfuretin | Atf3 | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CELL APOPTOSIS | ACTIVATING TRANSCRIPTION FACTOR-3 | BIOPHYSICS | GENE | INSULIN-RESISTANCE | INFLAMMATION | ADIPOCYTE DIFFERENTIATION | PPAR-GAMMA | EXPRESSION | ADIPOSE-TISSUE | Prevention | Glucose metabolism | Body weight | Physiological aspects | Glucose | Health aspects | Dextrose | Protein binding
Journal Article
Biomolecules & Therapeutics(구 응용약물학회지), ISSN 1976-9148, 2019, Volume 27, Issue 1, pp. 107 - 116
The global obesity epidemic and associated metabolic diseases require alternative biological targets for new therapeutic strategies. In this study, we show... 
Obesity | Adipocyte | Metabolic diseases | Sulfuretin | Diabetes | Atf3
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P1024 - P1024
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P831 - P831
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P833 - P833
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P464 - P464
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P833 - P834
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P661 - P661
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P1042 - P1042
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P434 - P435
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2019, Volume 116, Issue 25, pp. 12516 - 12523
BACE1 is the rate-limiting enzyme for amyloid-p peptides (An) generation, a key event in the pathogenesis of Alzheimer's disease (AD). By an unknown mechanism,... 
BETA-SECRETASE | APP | 5xFAD | 3xTg-AD mice | SEQUENCE-SPECIFIC CONTROL | MULTIDISCIPLINARY SCIENCES | PARTIAL REDUCTION | BACE1 | NONCODING RNA | NRF2 | ANTIOXIDANT | DISEASE | MICE | ENZYMATIC-ACTIVITY | INHIBITOR | Alzheimer's disease | Enzymes | Advertising executives | Antisense RNA | Analysis
Journal Article
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