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The Journal of Cell Biology, ISSN 0021-9525, 4/2010, Volume 189, Issue 2, pp. 223 - 232
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 04/2019, Volume 49, Issue 1, pp. 1 - 3
How organ morphogenesis specifies cell fate and whether organ progenitors are predetermined or specified via niche signals are critical developmental biology... 
DEVELOPMENTAL BIOLOGY | CELL BIOLOGY | Stem cell research | Developmental biology | Stem cells
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 535, Issue 7612, pp. 430 - 434
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7612, p. 430
Insulin-dependent diabetes is a complex multifactorial disorder characterized by loss or dysfunction of β-cells. Pancreatic β-cells differ in size, glucose... 
Islands of Langerhans | Physiological aspects | Identification and classification | Cells | Studies | Rodents | Insulin resistance | Glucose | Diabetes | Metabolism | Gene expression | Insulin
Journal Article
DEVELOPMENT, ISSN 0950-1991, 06/2019, Volume 146, Issue 12, p. dev173849
Deciphering mechanisms of endocrine cell induction, specification and lineage allocation in vivo will provide valuable insights into how the islets of... 
NEUROGENIN3 | Neurog3 | PHOSPHORYLATION | Endocrine progenitor-precursor | DEVELOPMENTAL BIOLOGY | ORGANOGENESIS | Single cell RNA sequencing | MAINTENANCE | ENDOCRINE PROGENITORS | Mouse | Endocrinogenesis | Endocrine cell allocation | DIFFERENTIATION | EXPRESSION | LINEAGE | PLEXUS
Journal Article
Molecular Metabolism, ISSN 2212-8778, 06/2019, Volume 24, pp. 80 - 97
Hundreds of missense mutations in the coding region of exist; however, if these mutations predispose to diabetes mellitus is unknown. In this study, we... 
Transactivation domain | PDX1 | PDX1-Bound genes | β-Cell differentiation | Insulin secretion | PROGENITORS | PANCREAS | beta-Cell differentiation | PLURIPOTENT STEM-CELLS | EPITHELIUM | GENES | ENDOCRINOLOGY & METABOLISM | TRANSCRIPTION FACTOR | EXPRESSION | ASSOCIATION | REVEALS
Journal Article
Molecular Metabolism, ISSN 2212-8778, 03/2018, Volume 9, pp. 57 - 68
Homozygous loss-of-function mutations in the gene coding for the homeobox transcription factor (TF) PDX1 leads to pancreatic agenesis, whereas heterozygous... 
ChIP-seq | PDX1 | SNPs | T2DM | GWAS | iPSC | VARIANTS | BETA-CELLS | PLURIPOTENT STEM-CELLS | MORPHOGENESIS | MUTATION | ENDOCRINOLOGY & METABOLISM | GENERATION | DIFFERENTIATION | TRANSCRIPTION FACTOR | EXPRESSION | IPSC LINE | Myeloid Ecotropic Viral Integration Site 1 Protein - metabolism | Diabetes Mellitus, Type 2 - genetics | Homeodomain Proteins - metabolism | Humans | Diabetes Mellitus, Type 2 - metabolism | Transcription Factor 7-Like 2 Protein - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Insulin-Secreting Cells - metabolism | Trans-Activators - genetics | Myeloid Ecotropic Viral Integration Site 1 Protein - genetics | Cell Differentiation | Insulin-Secreting Cells - cytology | Membrane Proteins - metabolism | Regulatory Factor X Transcription Factors - metabolism | Induced Pluripotent Stem Cells - cytology | Hepatocyte Nuclear Factor 1-beta - genetics | Hepatocyte Nuclear Factor 1-beta - metabolism | Induced Pluripotent Stem Cells - metabolism | Genome-Wide Association Study | Transcription Factor 7-Like 2 Protein - genetics | Membrane Proteins - genetics | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Chromatin Assembly and Disassembly | Homeodomain Proteins - genetics | Enhancer Elements, Genetic | Regulatory Factor X Transcription Factors - genetics | Protein Binding | Trans-Activators - metabolism | Polymorphism, Single Nucleotide | Index Medicus
Journal Article