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Head & Neck, ISSN 1043-3074, 04/2019, Volume 41, Issue 4, pp. E48 - E54
For locally recurrent head and neck cancer, re-irradiation with modern techniques like stereotactic body radiotherapy is a promising, possibly curative... 
Head and neck cancer | Care and treatment | Squamous cell carcinoma | Relapse | Radiosurgery | Diseases | Nasopharyngeal carcinoma | Remission | Radiation therapy | Head & neck cancer | Patients | Cancer therapies
Journal Article
International Journal of Cancer, ISSN 0020-7136, 01/2016, Volume 138, Issue 1, pp. 171 - 181
We examined the prognostic value of tumour‐infiltrating lymphocytes (TILs) in patients with squamous cell carcinoma of the head and neck (SCCHN) after surgery... 
prognostic | SCCHN | postoperative chemoradiotherapy | CD8 | DKTK‐ROG | HPV | DKTK-ROG | SURVIVAL | PERIPHERAL-CIRCULATION | CHEMOTHERAPY | TUMOR-INFILTRATING LYMPHOCYTES | ONCOLOGY | ANTITUMOR IMMUNE-RESPONSES | OROPHARYNGEAL CANCER | SQUAMOUS-CELL CARCINOMA | HUMAN-PAPILLOMAVIRUS STATUS | RADIOTHERAPY | T-CELLS | Prognosis | Tumor Virus Infections - virology | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Papillomaviridae - genetics | Squamous Cell Carcinoma of Head and Neck | Carcinoma, Squamous Cell - mortality | Neoplasm Grading | Postoperative Care | Biomarkers, Tumor - metabolism | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Papillomavirus Infections - virology | Papillomavirus Infections - complications | Head and Neck Neoplasms - therapy | Carcinoma, Squamous Cell - therapy | Immunophenotyping | Treatment Outcome | Head and Neck Neoplasms - pathology | Tumor Virus Infections - complications | Carcinoma, Squamous Cell - etiology | Phenotype | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Head and Neck Neoplasms - etiology | Aged | Biomarkers, Tumor - genetics | Head and Neck Neoplasms - mortality | CD8-Positive T-Lymphocytes - immunology | Neoplasm Staging | DNA, Viral | Lymphocytes, Tumor-Infiltrating - immunology | Consortia | Cancer patients | Care and treatment | Squamous cell carcinoma | Lymphocytes | Patient outcomes | Oncology, Experimental | Radiation | Research | Papillomavirus infections | Cancer | Surgery | Medical prognosis | Deoxyribonucleic acid--DNA | Tumors
Journal Article
International Journal of Cancer, ISSN 0020-7136, 01/2015, Volume 136, Issue 2, pp. 278 - 288
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 11/2019, Volume 9
Background: Definitive chemoradiotherapy (CRT) is the primary treatment for non-metastatic anal squamous cell carcinoma (ASCC). Despite favorable treatment... 
Albumin | Squamous cell carcinoma | Care and treatment | Prognosis | C-reactive protein | Cancer | disease-free survival | anal cancer | biomarker | albumin
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, pp. e0198692 - e0198692
Purpose Stereotactic radiosurgery (SRS) is an established primary treatment for newly diagnosed brain metastases with high local control rates. However, data... 
GAMMA-KNIFE RADIOSURGERY | BREAST-CANCER | SOLID TUMORS | POSTOPERATIVE STEREOTACTIC RADIOSURGERY | MULTIDISCIPLINARY SCIENCES | SALVAGE THERAPY | SINGLE-CENTER | SURGICAL RESECTION | RADIOTHERAPY | CEREBRAL METASTASES | RADIATION-THERAPY | Carcinoma, Non-Small-Cell Lung - radiotherapy | Neoplasm Recurrence, Local - radiotherapy | Brain - diagnostic imaging | Follow-Up Studies | Humans | Middle Aged | Brain Neoplasms - pathology | Lung Neoplasms - pathology | Male | Neoplasm Recurrence, Local - mortality | Radiosurgery - adverse effects | Feasibility Studies | Patient Selection | Neoplasm Recurrence, Local - pathology | Brain Neoplasms - secondary | Carcinoma, Non-Small-Cell Lung - secondary | Aged, 80 and over | Adult | Female | Retrospective Studies | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Radiosurgery - methods | Neoplasm Recurrence, Local - secondary | Carcinoma, Non-Small-Cell Lung - pathology | Robotic Surgical Procedures - methods | Robotic Surgical Procedures - instrumentation | Melanoma - radiotherapy | Treatment Outcome | Brain - radiation effects | Radiosurgery - instrumentation | Melanoma - pathology | Carcinoma, Non-Small-Cell Lung - mortality | Melanoma - secondary | Radiation Injuries - etiology | Magnetic Resonance Imaging | Radiation Injuries - epidemiology | Breast Neoplasms - pathology | Survival Analysis | Brain - pathology | Aged | Retreatment - methods | Retreatment - adverse effects | Robotic Surgical Procedures - adverse effects | Melanoma - mortality | Treatment outcome | Usage | Care and treatment | Analysis | Brain cancer | Radiosurgery | Diagnosis | Brain | Toxicity | Lung cancer | Radiation | Oncology | Metastasis | Neurosurgery | Cancer therapies | Metastases | Consortia | Salvage | Surgery | Medical research | Melanoma | Feasibility studies | Non-small cell lung carcinoma | Breast cancer | Histology | Radiation therapy | Patients | Survival | Brain research | Irradiation | Radiology | Cancer | Tumors | Index Medicus
Journal Article
International Journal of Cancer, ISSN 0020-7136, 08/2017, Volume 141, Issue 3, pp. 594 - 603
We examined the prognostic role of PD‐1+ and CD8+ tumor infiltrating lymphocytes (TILs), and PD‐L1+ cells in patients with squamous cell carcinoma of the head... 
prognostic | SCCHN | chemoradiotherapy | PD‐1/PD‐L1 | CD8 | HPV | PD-1/PD-L1 | SURVIVAL | PD-L1 EXPRESSION | P16(INK4A) | TUMOR-INFILTRATING LYMPHOCYTES | HPV STATUS | MICROENVIRONMENT | ONCOLOGY | IMMUNE CHECKPOINT BLOCKADE | PD-L1 | SQUAMOUS-CELL CARCINOMA | PD-1 | ASSOCIATION | T-CELLS | Papillomavirus Infections - complications | Head and Neck Neoplasms - virology | Prognosis | Follow-Up Studies | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Head and Neck Neoplasms - therapy | Carcinoma, Squamous Cell - therapy | Programmed Cell Death 1 Receptor - metabolism | Male | Survival Rate | Chemoradiotherapy, Adjuvant | Head and Neck Neoplasms - metabolism | Head and Neck Neoplasms - pathology | B7-H1 Antigen - metabolism | Neoplasm Grading | Biomarkers, Tumor - metabolism | Female | Neoplasm Staging | Papillomaviridae - physiology | Cancer patients | Care and treatment | Squamous cell carcinoma | Analysis | Oncology, Experimental | Radiation | Metastasis | Research | Papillomavirus infections | Cancer | PD-1 protein | CD8 antigen | Viruses | Genomes | Metastases | Consortia | Human papillomavirus | Lymphocytes | Surgery | Neck | Deoxyribonucleic acid--DNA | Head | Markers | Radiation therapy | Gene expression | Patients | Survival | Inhibitors | Immune checkpoint | PD-L1 protein | Head and neck cancer | Infiltration | Tumors
Journal Article
PHYSICS IN MEDICINE AND BIOLOGY, ISSN 0031-9155, 08/2019, Volume 64, Issue 16, p. 165003
Many tumors including head and neck squamous cell carcinoma (HNSCC) spread along the lymphatic network. Current imaging modalities can only detect sufficiently... 
SQUAMOUS-CELL-CARCINOMA | OROPHARYNGEAL | CTV | head and neck cancer | ENGINEERING, BIOMEDICAL | TARGET VOLUMES | NCIC CTG | DELINEATION | lymph nodes | elective nodal irradiation | NORMATIVE EXPERT-SYSTEMS | NODE METASTASES | RADIOTHERAPY | Bayesian network | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | HKNPCSG | DAHANCA
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2485
Vismodegib, an inhibitor of the Hedgehog signaling pathway, is an approved drug for monotherapy in locally advanced or metastatic basal cell carcinoma (BCC).... 
Head and neck squamous cell carcinoma | Hedgehog signaling pathway | Basal cell carcinoma | Radiotherapy resistance | Vismodegib (GDC-0449) | SURVIVIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | radiotherapy resistance | TUMOR-CELLS | CULTURE | CHEMISTRY, MULTIDISCIPLINARY | vismodegib (GDC-0449) | hedgehog signaling pathway | BREAST-CANCER | REPAIR | NONMELANOMA SKIN-CANCER | MESSENGER-RNA | basal cell carcinoma | GLI GENES | head and neck squamous cell carcinoma | Carcinoma, Basal Cell - therapy | Carcinoma, Basal Cell - genetics | Zinc Finger Protein GLI1 - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Gamma Rays - therapeutic use | Gene Expression Regulation, Neoplastic | Hedgehog Proteins - metabolism | Head and Neck Neoplasms - metabolism | Tumor Suppressor Protein p53 - genetics | G2 Phase Cell Cycle Checkpoints - radiation effects | G2 Phase Cell Cycle Checkpoints - drug effects | Hedgehog Proteins - genetics | Survivin - genetics | Antineoplastic Agents - pharmacology | G1 Phase Cell Cycle Checkpoints - radiation effects | Skin Neoplasms - pathology | Survivin - metabolism | Signal Transduction | Skin Neoplasms - therapy | Zinc Finger Protein GLI1 - genetics | Radiation-Sensitizing Agents - pharmacology | Head and Neck Neoplasms - therapy | Tumor Suppressor Protein p53 - metabolism | Carcinoma, Squamous Cell - therapy | Carcinoma, Basal Cell - pathology | Hedgehog Proteins - antagonists & inhibitors | Organ Specificity | Carcinoma, Basal Cell - metabolism | Head and Neck Neoplasms - pathology | Skin Neoplasms - metabolism | Histones - genetics | Skin Neoplasms - genetics | Anilides - pharmacology | Cell Line, Tumor | Head and Neck Neoplasms - genetics | Combined Modality Therapy - methods | Pyridines - pharmacology | Histones - metabolism | G1 Phase Cell Cycle Checkpoints - drug effects | Cell proliferation | Biotechnology | p53 Protein | DNA damage | Homology | Kinases | DNA repair | Metastases | Proteins | Signal transduction | Radiosensitization | Cell cycle | Deoxyribonucleic acid--DNA | Sensitizing | IAP protein | Squamous cell carcinoma | Cell survival | Radiation therapy | Survivin | Gene expression | Signaling | Inhibitors | Glioma | Cell death | Hedgehog protein | Cell lines | Irradiation | Head and neck cancer | Viability | Apoptosis | Transcription factors | Genes | Skin cancer | Cell growth | Surgery | Growth factors | Metabolism | Mutation | Esophageal cancer | Tumors
Journal Article