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by Hakim, James G and Thompson, Jennifer and Kityo, Cissy and Hoppe, Anne and Kambugu, Andrew and van Oosterhout, Joep J and Lugemwa, Abbas and Siika, Abraham and Mwebaze, Raymond and Mweemba, Aggrey and Abongomera, George and Thomason, Margaret J and Easterbrook, Philippa and Mugyenyi, Peter and Walker, A Sarah and Paton, Nicholas I and Agweng, E and Awio, P and Bakeinyaga, G and Isabirye, C and Kabuga, U and Kasuswa, S and Katuramu, M and Kiweewa, F and Kyomugisha, H and Lutalo, E and Mulima, D and Musana, H and Musitwa, G and Musiime, V and Ndigendawan, M and Namata, H and Nkalubo, J and Labejja, P Ocitti and Okello, P and Olal, P and Pimundu, G and Segonga, P and Ssali, F and Tamale, Z and Tumukunde, D and Namala, W and Byaruhanga, R and Kayiwa, J and Tukamushaba, J and Abunyang, S and Eram, D and Denis, O and Lwalanda, R and Mugarura, L and Namusanje, J and Nankya, I and Ndashimye, E and Nabulime, E and Senfuma, O and Bihabwa, G and Buluma, E and Elbireer, A and Kamya, D and Katwere, M and Kiggundu, R and Komujuni, C and Laker, E and Lubwama, E and Mambule, I and Matovu, J and Nakajubi, A and Nakku, J and Nalumenya, R and Namuyimbwa, L and Semitala, F and Wandera, B and Wanyama, J and Mugerwa, H and Ninsiima, E and Ssenkindu, T and Mwebe, S and Atwine, L and William, H and Katemba, C and Acaku, M and Ssebutinde, P and Kitizo, H and Kukundakwe, J and Naluguza, M and Ssegawa, K and Namayanja and Nsibuka, F and Tuhirirwe, P and Fortunate, M and Acen, J and Achidri, J and Amone, A and Chamai, M and Ditai, J and Kemigisa, M and Kiconco, M and Matama, C and Mbanza, D and Nambaziira, F and ... and Europe Africa Research Network for Evaluation of Second-line Therapy (EARNEST) Trial Team and Europe Africa Res Network
The Lancet Infectious Diseases, ISSN 1473-3099, 01/2018, Volume 18, Issue 1, pp. 47 - 57
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2014, Volume 371, Issue 3, pp. 234 - 247
Journal Article
Lancet HIV, The, ISSN 2352-3018, 2017, Volume 4, Issue 8, pp. e341 - e348
Journal Article
by Shi, Yuan and Thompson, Jennifer and Walker, A. Sarah and Paton, Nicholas I and Cheung, Yin Bun and Agweng, E and Awio, P and Bakeinyaga, G and Isabirye, C and Kabuga, U and Kasuswa, S and Katuramu, M and Kityo, C and Kiweewa, F and Kyomugisha, H and Lutalo, E and Mugyenyi, P and Mulima, D and Musana, H and Musitwa, G and Musiime, V and Ndigendawan, M and Namata, H and Nkalubo, J and Labejja, P. Ocitti and Okello, P and Olal, P and Pimundu, G and Segonga, P and Ssali, F and Tamale, Z and Tumukunde, D and Namala, W and Byaruhanga, R and Kayiwa, J and Tukamushaba, J and Abunyang, S and Eram, D and Denis, O and Lwalanda, R and Mugarura, L and Namusanje, J and Nankya, I and Ndashimye, E and Nabulime, E and Mulima, D and Senfuma, O and Bihabwa, G and Buluma, E and Easterbrook, P and Elbireer, A and Kambugu, A and Kamya, D and Katwere, M and Kiggundu, R and Komujuni, C and Laker, E and Lubwama, E and Mambule, I and Matovu, J and Nakajubi, A and Nakku, J and Nalumenya, R and Namuyimbwa, L and Semitala, F and Wandera, B and Wanyama, J and Mugerwa, H and Lugemwa, A and Ninsiima, E and Ssenkindu, T and Mwebe, S and Atwine, L and William, H and Katemba, C and Abunyang, S and Acaku, M and Ssebutinde, P and Kitizo, H and Kukundakwe, J and Naluguza, M and Ssegawa, K and Nsibuka, F and Tuhirirwe, P and Fortunate, M and Acen, J and Achidri, J and Amone, A and Chamai, M and Ditai, J and Kemigisa, M and Kiconco, M and Matama, C and Mbanza, D and Nambaziira, F and Odoi, M. Owor and Rweyora, A and Tumwebaze, G and Kalanzi, H and Katabaazi, J and ... and EARNEST Trial Team and for the EARNEST Trial Team
Health and Quality of Life Outcomes, ISSN 1477-7525, 05/2019, Volume 17, Issue 1, pp. 83 - 9
Journal Article
PLoS medicine, ISSN 1549-1676, 12/2018, Volume 15, Issue 12, p. e1002706
Background In sub-Saharan Africa, individuals infected with HIV who are severely immunocompromised have high mortality (about 10%) shortly after starting... 
MORTALITY | BIOMARKERS | SOUTH-AFRICA | MEDICINE, GENERAL & INTERNAL | IMMUNE RECONSTITUTION | EFAVIRENZ | ADULTS | INFECTION | RESTORATION | IMMUNODEFICIENCY | CHILDREN | HIV Infections - diagnostic imaging | Africa - epidemiology | Zimbabwe - epidemiology | Drug Administration Schedule | Follow-Up Studies | Kenya - epidemiology | HIV Infections - epidemiology | Humans | Raltegravir Potassium - administration & dosage | Child, Preschool | Malawi - epidemiology | Uganda - epidemiology | Male | Disease Progression | Anti-HIV Agents - administration & dosage | Young Adult | Anti-Retroviral Agents - administration & dosage | Adolescent | Adult | Female | HIV Infections - drug therapy | Child | Health Services Accessibility - trends | Drug therapy | HIV infection | Raltegravir | Testing | Therapy | RNA-directed DNA polymerase | Viremia | Funding | Clinical trials | Risk | Viruses | Infections | Tenofovir | Randomization | Motivation | Antiretroviral agents | Nucleoside reverse transcriptase inhibitors | Human immunodeficiency virus--HIV | Children | Adolescents | Genotypes | Supervision | University colleges | Integrase | Antiretroviral drugs | Medical research | Mortality | Immune reconstitution | Inflammation | Disease control | Antiretroviral therapy | Morbidity | CD4 antigen | Medicine | Amplification | Non-nucleoside reverse transcriptase inhibitors | Inhibitors | Councils | Abacavir | Nucleosides | Biomarkers | Mutation | HIV | Human immunodeficiency virus
Journal Article
by Post, Frank A and Szubert, Alexander J and Prendergast, Andrew J and Johnston, Victoria and Lyall, Hermione and Fitzgerald, Felicity and Musiime, Victor and Musoro, Godfrey and Chepkorir, Priscilla and Agutu, Clara and Mallewa, Jane and Rajapakse, Chathurika and Wilkes, Helen and Hakim, James and Mugyenyi, Peter and Sarah Walker, A and Gibb, Diana M and Pett, Sarah L and Kityo, C and Wavamunno, P and Nambi, E and Ocitti, P and Ndigendawani, M and Portal, F and Kabahenda, S and Kemigisa, M and Acen, J and Olebo, D and Mpamize, G and Amone, A and Okweny, D and Mbonye, A and Nambaziira, F and Rweyora, A and Kangah, M and Kabaswahili, V and Abach, J and Abongomera, G and Omongin, J and Aciro, I and Philliam, A and Arach, B and Ocung, E and Amone, G and Miles, P and Adong, C and Tumsuiime, C and Kidega, P and Otto, B and Apio, F and Baleeta, K and Mukuye, A and Abwola, M and Ssennono, F and Baliruno, D and Tuhirwe, S and Namisi, R and Kigongo, F and Kikyonkyo, D and Mushahara, F and Tusiime, J and Musiime, A and Nankya, A and Atwongyeire, D and Sirikye, S and Mula, S and Noowe, N and Lugemwa, A and Kasozi, M and Mwebe, S and Atwine, L and Senkindu, T and Natuhurira, T and Katemba, C and Ninsiima, E and Acaku, M and Kyomuhangi, J and Ankunda, R and Tukwasibwe, D and Ayesiga, L and Nathoo, K and Bwakura-Dangarembizi, M and Reid, A and Chidziva, E and Mhute, T and Tinago, G.C and Bhiri, J and Mudzingwa, S and Phiri, M and Steamer, J and Nhema, R and Warambwa, C and Mutsai, S and Nemasango, B and Moyo, C and Chitongo, S and Rashirai, K and Vhembo, S and Mlambo, B and Nkomani, S and ... and Reduction EArly MortaLITY and Reduction of EArly mortaLITY in HIV-infected adults and children starting antiretroviral therapy (REALITY) Trial Team
Clinical Infectious Diseases, ISSN 1058-4838, 03/2018, Volume 66, Issue suppl_2, pp. S132 - S139
Background. In sub-Saharan Africa, 20%-25% of people starting antiretroviral therapy (ART) have severe immunosuppression; approximately 10% die within 3... 
mortality | HIV | morbidity | antiretroviral therapy | Africa | INFECTIOUS DISEASES | HIV-INFECTION | RECONSTITUTION INFLAMMATORY SYNDROME | DISEASE | MICROBIOLOGY | IMMUNOLOGY | CHILDREN | Advanced HIV Disease
Journal Article
Clinical infectious diseases, ISSN 1058-4838, 2018, Volume 66, Issue suppl_2, pp. S140 - S146
Background. Severely immunocompromised human immunodefciency virus (HIV)-infected individuals have high mortality shortly afer starting antiretroviral therapy... 
mortality | immunosuppression | HIV | Africa | BIOMARKERS | INFECTIOUS DISEASES | INITIATION | MICROBIOLOGY | ANTIRETROVIRAL THERAPY | IMMUNOLOGY | INFECTED ADULTS | CHILDREN | Advanced HIV Disease
Journal Article