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Journal of Clinical Investigation, ISSN 0021-9738, 08/2014, Volume 124, Issue 8, pp. 3514 - 3528
Development of the vascular disease pulmonary hypertension (PH) involves disparate molecular pathways that span multiple cell types. MicroRNAs (miRNAs) may... 
SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | HUMAN-DISEASE | ARTERIAL-HYPERTENSION | PPAR-GAMMA | TARGETS | RECEPTOR | SMOOTH-MUSCLE-CELLS | PROLIFERATION | MEDICINE | HYPOXIA | Up-Regulation | Cell Proliferation | Humans | Myocytes, Smooth Muscle - pathology | MicroRNAs - metabolism | Gene Regulatory Networks | PPAR gamma - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Pulmonary Artery - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Computer Simulation | Fibroblast Growth Factor 2 - metabolism | Myocytes, Smooth Muscle - metabolism | STAT3 Transcription Factor - metabolism | Apelin | Disease Models, Animal | Signal Transduction | Endothelial Cells - metabolism | Mice, Inbred C57BL | Hypertension, Pulmonary - genetics | Hypoxia - complications | Systems Theory | Animals | Models, Biological | Octamer Transcription Factor-3 - metabolism | Mice | MicroRNAs - genetics | Endothelial Cells - pathology | Hypertension, Pulmonary - etiology | Hypertension, Pulmonary - pathology | Pulmonary Artery - pathology | MicroRNA | Physiological aspects | Development and progression | Genetic aspects | Fibroblast growth factors | Research | Pulmonary hypertension | Plasma | Disease | Pulmonary arteries | Pathogenesis | Smooth muscle | Regulation | Intubation | Kinases | Experiments
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 04/2007, Volume 7, Issue 7, pp. 641 - 649
Chemically modified antisense oligonucleotides are currently progressing in multiple clinical trials. Among several chemical modifications made, modification... 
Antisense oligonucleotides | RNA affinity | DNA decamer duplex | Arabino nucleic acids | RNase H enzyme | SMALL INTERFERING RNA | BIOPHYSICAL PROPERTIES | CHEMISTRY, MEDICINAL | LOCKED NUCLEIC-ACID | CRYSTAL-STRUCTURE | STABILITY | DNA | EXONUCLEASE RESISTANCE | DUPLEXES | CHEMICAL-MODIFICATIONS | MAMMALIAN-CELLS
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 1/2009, Volume 37, Issue 1, pp. 70 - 77
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2014, Volume 124, Issue 1, pp. 222 - 236
Acute myelogenous leukemia (AML) subtypes that result from oncogenic activation of homeobox (HOX) transcription factors are associated with poor prognosis. The... 
HEMATOPOIETIC-CELLS | PROGENITOR CELLS | HOX | MEDICINE, RESEARCH & EXPERIMENTAL | ACUTE MYELOGENOUS LEUKEMIA | IN-VIVO | NPM1 MUTATIONS | ACUTE MYELOID-LEUKEMIA | GENE-EXPRESSION PROFILE | MLL | STEM | Phosphorothioate Oligonucleotides - genetics | Homeodomain Proteins - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Regulatory Sequences, Nucleic Acid | Transcriptome | Induction Chemotherapy | MicroRNAs - metabolism | Neoplasm Proteins - metabolism | DNA-Binding Proteins - metabolism | Cell Transformation, Neoplastic - genetics | Base Sequence | Pre-B-Cell Leukemia Transcription Factor 1 | Binding Sites | Leukemia, Myeloid, Acute - therapy | Neoplastic Stem Cells - physiology | Doxorubicin - administration & dosage | Proto-Oncogene Proteins - metabolism | Leukemia, Myeloid, Acute - pathology | Mice, Inbred C57BL | Combined Modality Therapy | Gene Expression Regulation, Leukemic | Mice, SCID | Cell Transformation, Neoplastic - metabolism | Cytarabine - administration & dosage | Transcription Factors - metabolism | Xenograft Model Antitumor Assays | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Binding | Mice, Inbred NOD | Mice | MicroRNAs - genetics | Myeloid Ecotropic Viral Integration Site 1 Protein | MicroRNA | Genetic transcription | Research | Flow cytometry | Insects | Leukemia | Cloning | MicroRNAs | Cell cycle | Software | Signatures | Gene expression | Deoxyribonucleic acid--DNA | Children & youth | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2015, Volume 5, Issue 1, p. 18277
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2017, Volume 114, Issue 8, pp. E1509 - E1518
Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by progressive motor neuron loss and caused by mutations in SMN1 (Survival Motor... 
LncRNA | PRC2 | SMN | Spinal muscular atrophy | CELLS | lncRNA | PROTEIN | CHROMATIN | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | SINGLE NUCLEOTIDE | MOTOR-NEURON GENE | NONCODING RNAS | MOUSE MODEL | spinal muscular atrophy | EXPRESSION | SEVERITY | Biological Sciences | PNAS Plus
Journal Article