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PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, pp. e39586 - e39586
Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson Disease, Alzheimer Disease... 
MITOCHONDRIAL APOPTOSIS | TRANSCRIPTION FACTOR CHOP | UNFOLDED PROTEIN RESPONSE | INDUCED APOPTOSIS | KINASE | BIOLOGY | GENE-EXPRESSION | SYMPATHETIC NEURONS | DEATH | ENDOPLASMIC-RETICULUM STRESS | BH3-ONLY PROTEINS | Transcription Factor CHOP - genetics | Apoptosis - drug effects | Neurons - cytology | Bcl-2-Like Protein 11 | Forkhead Transcription Factors - metabolism | Telencephalon - drug effects | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Neurons - metabolism | Neurons - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Cell Survival - physiology | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Tumor Suppressor Proteins - metabolism | Telencephalon - metabolism | Telencephalon - cytology | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Forkhead Transcription Factors - genetics | Apoptosis Regulatory Proteins - metabolism | Animals | Signal Transduction - drug effects | Tunicamycin - pharmacology | Signal Transduction - physiology | Mice | Apoptosis - physiology | Forkhead Box Protein O3 | Transcription Factor CHOP - metabolism | Endoplasmic Reticulum Stress - physiology | Nervous system diseases | Parkinson's disease | Huntington's chorea | Neurons | Tumor proteins | Protein kinases | Apoptosis | Phosphorylation | Transcription factors | Transcription | p53 Protein | Tunicamycin | Homology | AKT protein | CCAAT/enhancer-binding protein | Kinases | Proteins | Signal transduction | Mitochondria | Cell activation | Cell growth | Cascades | Rodents | Forkhead protein | Alzheimer's disease | Movement disorders | Deoxyribonucleic acid--DNA | FOXO3 protein | Stresses | Neurodegenerative diseases | Mortality | Gene expression | Stress | Neurological diseases | Pathology | Signaling | Cell death | Endoplasmic reticulum | CHOP protein | BIM protein | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e86338 - e86338
Journal Article
Oncotarget, 2015, Volume 6, Issue 20, pp. 17895 - 17910
Aberrations in the mTOR (mechanistic target of rapamycin) axis are frequently reported in cancer. Using publicly available tumor genome sequencing data, we... 
mTOR | Mutations | Rapamycin | Renal cancer | RHEB | Kidney Neoplasms - genetics | TOR Serine-Threonine Kinases - metabolism | Humans | Carcinoma, Renal Cell - genetics | Databases, Genetic | Multiprotein Complexes - genetics | Ras Homolog Enriched in Brain Protein | Intracellular Signaling Peptides and Proteins - metabolism | Kidney Neoplasms - metabolism | GTPase-Activating Proteins - metabolism | Mechanistic Target of Rapamycin Complex 2 | Mechanistic Target of Rapamycin Complex 1 | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | TOR Serine-Threonine Kinases - genetics | Transfection | DNA Mutational Analysis | Tumor Suppressor Proteins - genetics | HEK293 Cells | Biomarkers, Tumor - metabolism | Neuropeptides - genetics | Carcinoma, Renal Cell - drug therapy | Intracellular Signaling Peptides and Proteins - genetics | Protein Structure, Tertiary | Genetic Predisposition to Disease | Tumor Suppressor Proteins - metabolism | Carcinoma, Renal Cell - pathology | Monomeric GTP-Binding Proteins - genetics | Sirolimus - pharmacology | Carcinoma, Renal Cell - metabolism | Point Mutation | Drug Resistance, Neoplasm - genetics | Phenotype | Signal Transduction - drug effects | Adaptor Proteins, Signal Transducing - genetics | Kidney Neoplasms - pathology | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | GTPase-Activating Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Kidney Neoplasms - drug therapy | Index Medicus
Journal Article
The European journal of neuroscience, ISSN 0953-816X, 10/2017, Volume 46, Issue 7, pp. 2241 - 2252
A greater understanding of neural mechanisms that contribute to anxiety is needed in order to develop better therapeutic interventions. The current study... 
microRNA | Polycomb Repressive Complex 2 | Anxiety | Amygdala | miR-101a-3p | Ezh2
Journal Article
Journal Article
Mucosal Immunology, ISSN 1933-0219, 11/2018, Volume 11, Issue 6, pp. 1694 - 1704
Intestinal macrophages in healthy human mucosa are profoundly down-regulated for inflammatory responses (inflammation anergy) due to stromal TGF-β inactivation... 
Cytomegalovirus | Infections | Inflammation | Mucous membrane | Index Medicus
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 01/2013, Volume 266, Issue 2, pp. 233 - 244
Histone deacetylase (HDAC) inhibitors are potent anticancer agents and show efficacy against various human neoplasms. Vorinostat is a potent HDAC inhibitor and... 
mTOR | Histone deacetylase inhibitors | Vorinostat | Skin cancer | MTOR | APOPTOSIS | ACTIVATION | MANAGEMENT | MECHANISMS | DEATH | SKIN CANCERS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | EXPRESSION | EPIDEMIOLOGY | PROGRESSION | Skin Neoplasms - drug therapy | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Carcinoma, Squamous Cell - pathology | Humans | Cyclins - genetics | Histone Deacetylase Inhibitors - administration & dosage | Antineoplastic Agents - administration & dosage | Dose-Response Relationship, Drug | Hydroxamic Acids - administration & dosage | Female | Antineoplastic Agents - pharmacology | Hydroxamic Acids - pharmacology | Skin Neoplasms - pathology | Cell Survival - drug effects | Histone Deacetylases - genetics | Proliferating Cell Nuclear Antigen - analysis | Down-Regulation - drug effects | Xenograft Model Antitumor Assays | Animals | Carcinoma, Squamous Cell - drug therapy | Signal Transduction - drug effects | Mice, Nude | Histone Deacetylase Inhibitors - pharmacology | Cell Proliferation - drug effects | Mice | Immunocompromised Host | Transplantation of organs, tissues, etc | Squamous cell carcinoma | Skin | Tumor proteins | Growth | Cell proliferation | TOR protein | Histone deacetylase | Animal models | Cell survival | Therapeutic applications | Tumor cells | Extracellular signal-regulated kinase | AKT protein | Data processing | p53 protein | Signal transduction | Proliferating cell nuclear antigen | Xenografts | Histone H3 | Apoptosis | Tumors | squamous cell carcinoma | Index Medicus | SURGERY | PATIENTS | INHIBITION | ACETYLATION | CELL PROLIFERATION | MICE | TUMOR CELLS | EPITHELIOMAS | SKIN | PROTEINS | 60 APPLIED LIFE SCIENCES | skin cancer
Journal Article