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Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 10/2019, Volume 71, Issue 4, pp. 1361 - 1373
Research on intranasal delivery of drugs, peptides, and proteins has grown over the past decade as an alternate way to deliver substrates to the brain. Recent... 
Brain | Animal models | Drug delivery systems | Peptides | Genes | Memory | Cognition | Drug delivery | Hypothalamus | Gene expression | Insulin | Substrates | Proteins | Signal transduction | Molecular modelling | Pathways | Olfactory bulb | Alzheimer's disease | Hippocampus
Journal Article
Toxicological Sciences, ISSN 1096-6080, 09/2019
Abstract The airway epithelium is critical for maintaining innate and adaptive immune responses, and occupational exposures that disrupt its immune homeostasis... 
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 07/2017, Volume 45, Issue 7, pp. 867 - 882
Journal Article
Global Change Biology, ISSN 1354-1013, 03/2019, Volume 25, Issue 3, pp. 963 - 977
Elevated concentrations of CO in seawater can disrupt numerous sensory systems in marine fish. This is of particular concern for Pacific salmon because they... 
ocean acidification | GABA | salmon | olfactory bulb | olfactory rosette
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2017, Volume 112, pp. 191 - 192
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.freeradbiomed.2017.10.301 
Physiological aspects | Cysteine | Thiols | DNA binding proteins | Analysis | Cystine
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2017, Volume 112, pp. 191 - 192
Journal Article
Autophagy, ISSN 1554-8627, 09/2019, Volume 15, Issue 9, pp. 1592 - 1605
The destruction of mitochondria through macroautophagy (autophagy) has been recognised as a major route of mitochondrial protein degradation since its... 
mitophagy | protein turnover | stable isotope labelling | proteomics | Drosophila | mitochondria | Autophagy | turnover rate | protein degradation | OXIDATIVE STRESS | HOMEOSTASIS | RESTRICTION | CELL BIOLOGY | HETEROGENEITY | DATABASE | PROTEASOME | DYSFUNCTION | TISSUES | FLYATLAS | Index Medicus
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 07/2017, Volume 45, Issue 7, p. 867
The constitutive androstane receptor (CAR/Nr1i3) is an important xenobiotic-sensing nuclear receptor that is highly expressed in the liver and is well known to... 
Neonates | Enzyme activity | Liver | Genes | Gene regulation | Activation | Risk factors | Western blotting | Gene sequencing | Proteins | Enzymatic activity | Biotransformation | Children | Species | Age | Genotypes | Efflux | Transgenic mice | Pharmacology | Gene expression | Ribonucleic acid--RNA | Age factors | Side effects | Mice | Adults | Pharmacokinetics | Nuclear reactions
Journal Article
eLife, ISSN 2050-084X, 05/2019, Volume 8
Mechanisms driving the initiation of brain folding are incompletely understood. We have previously characterized mouse models recapitulating human -related... 
Brain | Verteporfin | Hydrocephalus | Tetracyclines | Analysis | Tetracycline | Animal models | Epilepsy | Cortex | Kinases | Embryos | Cell adhesion & migration | 1-Phosphatidylinositol 3-kinase | Yes-associated protein | Genotype & phenotype | Brain research | Cell adhesion | Software | Mutation | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A19654 - A19654
IntroductionWe have previously shown, in a mouse model, that gestational exposure to diesel exhaust causes placental inflammation, as well as increased cardiac... 
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 10/2016, Volume 153, Issue 2, pp. 282 - 302
Safety concerns have emerged regarding the potential long-lasting effects due to developmental exposure to xenobiotics. The pregnane X receptor (PXR) and... 
Drug-processing genes | PXR | Neonatal exposure | PPARα | CAR | PPAR alpha | drug-processing genes | DRUG-METABOLIZING-ENZYMES | RNA-SEQUENCING QUANTIFICATION | PREGNANE-X-RECEPTOR | CROSS-TALK | neonatal exposure | CONSTITUTIVE ANDROSTANE RECEPTOR | TISSUE DISTRIBUTION | GENE-EXPRESSION | HEPATIC ONTOGENY | TOXICOLOGY | ELIMINATION PATHWAYS | PHASE-I
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 11/2017, Volume 45, Issue 11, p. 1197
The gut microbiome is a novel frontier in xenobiotic metabolism. Polybrominated diphenyl ethers (PBDEs), especially BDE-47 (2, 2′, 4, 4′-tetrabromodiphenyl... 
Metabolomics | Gnotobiotics | Enzyme activity | Toxicity | Liver | Genes | Gene regulation | Cytochrome P450 | Microbiomes | CYP1A2 protein | Metabolism | Gene expression | Ribonucleic acid--RNA | Gene sequencing | Polybrominated diphenyl ethers | Enzymatic activity | Metabolites | Contaminants | Biotransformation | Rodents | Mice | In vivo methods and tests | Ethers
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 02/2013, Volume 41, Issue 2, pp. 332 - 342
Journal Article
Environmental Science & Technology, ISSN 0013-936X, 02/2016, Volume 50, Issue 4, pp. 1990 - 1990
The use of sentinel species for population and ecosystem health assessments has been advocated as part of a One Health perspective. The Arctic is experiencing... 
Journal Article
Redox Biology, ISSN 2213-2317, 07/2018, Volume 17, Issue C
Protein S-glutathionylation is an important reversible post-translational modification implicated in redox signaling. Oxidative modifications to protein thiols... 
muscle contraction, Post-translational modification (PTM), S-glutathionylation, redox signaling, skeletal muscle, excitation-contraction coupling, redox proteomics
Journal Article
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