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Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 4454 - 4454
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2009, Volume 119, Issue 12, pp. 3626 - 3636
The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is dysregulated in various cancers, and its upregulation strongly correlates... 
MEDICINE, RESEARCH & EXPERIMENTAL | BREAST-CANCER CELLS | DEVELOPMENTAL REGULATORS | CELLULAR MEMORY | E-CADHERIN EXPRESSION | HEMATOPOIETIC STEM-CELLS | PROSTATE-CANCER | MYC TRANSGENIC MICE | SELF-RENEWAL | NF-KAPPA-B | TRANSCRIPTION FACTOR | Nasopharyngeal Neoplasms - genetics | Neoplasm Transplantation | Nasopharyngeal Neoplasms - metabolism | Epithelial Cells - metabolism | Cadherins - metabolism | Humans | Glycogen Synthase Kinase 3 beta | Transplantation, Heterologous | Phosphatidylinositol 3-Kinases - metabolism | Mesoderm - cytology | Repressor Proteins - antagonists & inhibitors | Nasopharyngeal Neoplasms - pathology | Cadherins - genetics | Epithelial Cells - cytology | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Nasopharyngeal Neoplasms - etiology | Snail Family Transcription Factors | Nasopharynx - metabolism | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | PTEN Phosphohydrolase - genetics | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Neoplasm Invasiveness | Down-Regulation | Gene Silencing | PTEN Phosphohydrolase - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Glycogen Synthase Kinase 3 - metabolism | Transcription Factors - metabolism | Animals | Polycomb Repressive Complex 1 | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mesoderm - metabolism | Mice | Nasopharynx - cytology | Chromatin | Care and treatment | Lymphomas | Research | Analysis | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 448 - 448
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, pp. e75907 - e75907
Based on gene expression patterns, breast cancers can be divided into subtypes that closely resemble various developmental stages of normal mammary epithelial... 
ADULT HUMAN BREAST | STEM-CELLS | HUMAN-BREAST-CANCER | BASAL-LIKE SUBTYPE | MULTIDISCIPLINARY SCIENCES | EPIDERMAL-GROWTH-FACTOR | GENE-EXPRESSION | SUSTAINED ACTIVATION | FACTOR RECEPTOR | GLAND DEVELOPMENT | FACTOR-ALPHA | Cell Line | Mammary Glands, Human - cytology | Receptor, Epidermal Growth Factor - agonists | Humans | Immunoblotting | Epithelial Cells | Amphiregulin | Glycoproteins - pharmacology | Cell Differentiation - genetics | Microscopy, Confocal | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | EGF Family of Proteins | Intercellular Signaling Peptides and Proteins - pharmacology | Fluorescent Antibody Technique | Epidermal Growth Factor - pharmacology | Cell Differentiation - physiology | Transforming Growth Factor alpha - pharmacology | Keratin | Epidermal growth factor | Genetic aspects | Transforming growth factors | Cell differentiation | Gene expression | Telomerase | Cytokeratin | Cell culture | Telomerase reverse transcriptase | RNA-directed DNA polymerase | Breastfeeding & lactation | Epithelial cells | Genes | Differentiation (biology) | Transforming growth factor-a | AKT protein | Biology | Kinases | Proteins | Developmental stages | Rodents | Genetics | Mammary gland | Epidermal growth factor receptors | Extracellular signal-regulated kinase | Breast cancer | Molecular chains | 1-Phosphatidylinositol 3-kinase | Molecular modelling | Stem cells | Breast | Ligands | Cancer | Index Medicus
Journal Article
Development (Cambridge), ISSN 0021-9533, 03/2017, Volume 144, Issue 6, pp. 1072 - 1086
The ubiquitin ligases CBL and CBL-B are negative regulators of tyrosine kinase signaling with established roles in the immune system. However, their... 
Mouse | Casitas B-lineage lymphoma | Mammary gland development | Mammary stem cells | Basal cells | CBLB | Lgr5 | MTOR signaling | Luminal cells | C-CBL | BRANCHING MORPHOGENESIS | SELF-RENEWAL | DEVELOPMENTAL BIOLOGY | mTOR signaling | GLAND DEVELOPMENT | BREAST-CANCER | AKT INHIBITOR MK-2206 | SIGNALING PATHWAY | NEGATIVE REGULATION | SUSTAINED ACTIVATION | EPITHELIAL DEVELOPMENT | Proto-Oncogene Proteins c-cbl - metabolism | Epithelial Cells - metabolism | Receptors, G-Protein-Coupled - metabolism | Signal Transduction | TOR Serine-Threonine Kinases - metabolism | Cell Separation | Organoids - cytology | Mammary Tumor Virus, Mouse - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Cell Self Renewal - drug effects | Mammary Glands, Animal - cytology | Mice, Knockout | Mammary Glands, Animal - growth & development | Animals | Gene Deletion | Tamoxifen - pharmacology | Female | Integrases - metabolism | Mice | Adaptor Proteins, Signal Transducing - metabolism | Epithelial Cells - cytology | Proto-Oncogene Proteins c-akt - metabolism | Tyrosine | TOR protein | Ubiquitin | Epithelial cells | Stem cell transplantation | AKT protein | Tamoxifen | Gene deletion | Clonal deletion | Lymphocytes B | Organoids | Rodents | Stem cells | Cbl-b protein | Mammary gland | Protein-tyrosine kinase | Immune system | Index Medicus | 203 | Stem Cells and Regeneration
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167064 - e0167064
Journal Article
Journal of Cell Science, ISSN 0021-9533, 04/2017, Volume 130, Issue 7, pp. e1.2 - e1.2
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2010, Volume 107, Issue 37, pp. 16274 - 16279
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 5300 - 5300
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 01/2003, Volume 23, Issue 1, pp. 389 - 401
Journal Article
Oncotarget, ISSN 1949-2553, 08/2018, Volume 9, Issue 63, pp. 32191 - 32203
Solid tumors are 3D assemblies of cancer cells, together with multiple stromal cell types within an extracellular matrix. Yet, the vast majority of cell-based... 
Epithelial-mesenchymal transition | Hypoxia | Hydrogel | Lysyl oxidase
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e61757 - e61757
Journal Article
BMC CELL BIOLOGY, ISSN 1471-2121, 11/2009, Volume 10, Issue 1, pp. 84 - 84
Background: Epidermal growth factor receptor (EGFR) controls a wide range of cellular processes, and altered EGFR signaling contributes to human cancer. EGFR... 
CELL LUNG-CANCER | SIGNAL-TRANSDUCTION | GROWTH-FACTOR RECEPTOR | GEFITINIB | ACTIVATION | CBL-MEDIATED UBIQUITINYLATION | TYROSINE KINASE | C-CBL | DOWN-REGULATION | MUTATIONS | CELL BIOLOGY | Studies | Medical research | Phosphorylation | Ligands | Standard deviation | Mutation | Kinases | Manuscripts
Journal Article
Breast Cancer Research, ISSN 1465-5411, 11/2016, Volume 18, Issue 1, pp. 113 - 113
Journal Article
Cancer Research, ISSN 0008-5472, 05/2018, Volume 78, Issue 10, pp. 2524 - 2535
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2018, Volume 200, Issue 2, pp. 483 - 499
T cells use the endocytic pathway for key cell biological functions, including receptor turnover and maintenance of the immunological synapse. Some of the... 
EARLY ENDOSOMAL TRANSPORT | PROTEIN EHD1 | IMMUNE SYNAPSE | SURFACE EXPRESSION | DOWN-REGULATION | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | IMMUNOLOGICAL SYNAPSE | PLASMA-MEMBRANE | INTRAFLAGELLAR TRANSPORT | AUTOIMMUNE ENCEPHALOMYELITIS | Multigene Family | Encephalomyelitis, Autoimmune, Experimental - metabolism | Vesicular Transport Proteins - metabolism | Encephalomyelitis, Autoimmune, Experimental - immunology | Lymphoid Tissue - immunology | CD4-Positive T-Lymphocytes - immunology | Multiprotein Complexes - metabolism | Endocytosis | Lysosomes - metabolism | T-Lymphocytes - metabolism | Proteolysis | Female | Encephalomyelitis, Autoimmune, Experimental - genetics | Nuclear Proteins - genetics | Gene Expression | Receptors, Antigen, T-Cell - metabolism | Lymphocyte Activation | Vesicular Transport Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Lymphoid Tissue - metabolism | DNA-Binding Proteins - genetics | Gene Knockout Techniques | CD3 Complex - metabolism | Mice, Knockout | Protein Transport | Carrier Proteins - genetics | Animals | Protein Binding | T-Lymphocytes - immunology | Mice | Cell proliferation | Regulators | Oligodendrocyte-myelin glycoprotein | Encephalomyelitis | Myelin | Secretion | Glycoprotein | SNAP receptors | Homology | Immunological synapses | Lymphocytes T | CD3 antigen | Experimental allergic encephalomyelitis | CD4 antigen | Proteins | T-cell receptor | Immunology | Interleukin 2 | Lymphocytes | Rodents | Recycling | Regulatory proteins | Index Medicus | Abridged Index Medicus
Journal Article