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1. Full Text ID: 249
by Bang, Bo Ram and Saito, Takeshi
Cytokine, ISSN 1043-4666, 11/2015, Volume 76, Issue 1, p. 111
Currently, over 200 million people are chronically infected with Hepatitis C virus (HCV), which is the leading cause of end stage liver diseases. In order to... 
Hepatitis C virus | Liver diseases
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2. Full Text ID: 249: Hepatic macrophage regulation of Hepatitis C virus infection
by Bang, Bo Ram and Saito, Takeshi
Cytokine, ISSN 1043-4666, 11/2015, Volume 76, Issue 1, pp. 111 - 111
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3. Full Text Organ system view of the hepatic innate immunity in HCV infection
: Innate Defense Program Against HCV
by Bang, Bo-Ram and Elmasry, Sandra and Saito, Takeshi
Journal of Medical Virology, ISSN 0146-6615, 12/2016, Volume 88, Issue 12, pp. 2025 - 2037
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4. Full Text Tissue-specific regulation of p38α-mediated inflammation in ConA-induced acute liver damage
by Kang, Young Jun and Bang, Bo-Ram and Otsuka, Motoyuki and Otsu, Kinya
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 5/2015, Volume 194, Issue 10, pp. 4759 - 4766
Because p38α plays a critical role in inflammation, it has been an attractive target for the development of anti-inflammation therapeutics. However, p38α... 
p38α inhibitor | liver | inflammation | hepatotoxicity | p38α MAPK
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5. Full Text 315 – The Role of Peritoneal Macrophages in Spontaneous Bacterial Peritonitis (SBP)
by Zhao, Diana and Bang, Bo-Ram and Hagopian, Garo and Huizar, Giselle and Mehrotra, Sagarika and Kim, Ki-Yoon and Deurdulian, Corinne and Grant, Edward and Saito, Takeshi
Gastroenterology, ISSN 0016-5085, 05/2019, Volume 156, Issue 6, pp. S-1190 - S-1190
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6. Full Text The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation
by Bang, Bo-Ram and Han, Kyung Ho and Seo, Goo-Young and Croft, Michael and Kang, Young Jun
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 12
Abstract Two distinct p38 signaling pathways, classical and alternative, have been identified to regulate inflammatory responses in host defense and disease... 
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7. Full Text Detection of Occult Hepatitis C Virus Infection in Patients Who Achieved a Sustained Virologic Response to Direct-Acting Antiviral Agents for Recurrent Infection After Liver Transplantation
by Elmasry, Sandra and Wadhwa, Sanya and Bang, Bo-Ram and Cook, Linda and Chopra, Shefali and Kanel, Gary and Kim, Brian and Harper, Tammy and Feng, Zongdi and Jerome, Keith R and Kahn, Jeffrey A and Saito, Takeshi
Gastroenterology, ISSN 0016-5085, 2016, Volume 152, Issue 3, pp. 550 - 553.e8
Occult infection with hepatitis C virus (HCV) is defined as the presence of the HCV genome in either liver tissue or peripheral blood monocytes, despite... 
Gastroenterology and Hepatology | Persistence | Treatment Outcome | Limit of Detection | Viral Hibernation | REAL-TIME PCR | REPLICATION | DNA | RECIPIENTS | GASTROENTEROLOGY & HEPATOLOGY | Recurrence | Liver Transplantation | Prospective Studies | Virus Replication - genetics | Humans | Middle Aged | Fluorenes - therapeutic use | Hepacivirus - genetics | Male | RNA, Viral - blood | Alanine Transaminase - blood | Simeprevir - therapeutic use | Viral Load | Female | Imidazoles - therapeutic use | Drug Therapy, Combination | Benzimidazoles - therapeutic use | Sofosbuvir - therapeutic use | Antiviral Agents - therapeutic use | Ribavirin - therapeutic use | Hepatitis C, Chronic - drug therapy | Reverse Transcriptase Polymerase Chain Reaction | Hepatitis C, Chronic - blood | Aspartate Aminotransferases - blood | Sustained Virologic Response | Antiviral agents | Medical colleges | Relapse | RNA | Genomics | Liver | Biological products industry | Transplantation | Diseases | Virus diseases | Analysis | Research institutes | Drug therapy | Hepatitis C virus | Health aspects | Medical research | Medicine, Experimental | persistence | viral hibernation | limit of detection | treatment outcome
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8. Full Text Metformin reduces airway inflammation and remodeling via activation of AMP-activated protein kinase
by Park, Chan Sun and Bang, Bo-Ram and Kwon, Hyouk-Soo and Moon, Hee-Bom and Moon, Keun-Ai and Kim, Tae-Bum and Lee, Ki-Young and Cho, You Sook
Biochemical Pharmacology, ISSN 0006-2952, 12/2012, Volume 84, Issue 12, pp. 1660 - 1670
Recent reports have suggested that metformin has anti-inflammatory and anti-tissue remodeling properties. We investigated the potential effect of metformin on... 
Oxidative stress | Airway remodeling | Metformin | AMP-activated protein kinase (AMPK) | 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) | 5-Aminoimidazole-4- carboxamide-1-β-4-ribofuranoside (AICAR) | FIBROSIS | PROLIFERATION | 5-Aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) | PATHOGENESIS | MURINE MODEL | DIISOCYANATE-INDUCED ASTHMA | HEPATIC STELLATE CELLS | PATHWAY | PHARMACOLOGY & PHARMACY | EXPRESSION | PROGRESSION | AMP-Activated Protein Kinases - metabolism | Asthma - prevention & control | Metformin - pharmacology | Mice, Inbred C57BL | Transforming Growth Factor beta1 - metabolism | DNA Primers | Blotting, Western | Fibronectins - metabolism | Lung - enzymology | Animals | Base Sequence | Lung - drug effects | Female | Lung - metabolism | Mice | Mice, Inbred BALB C | Enzyme Activation | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Medical colleges | Protein kinases
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9. Full Text 624 - Clinical Outcomes of Occult Hepatitis C Infection in a Post-Liver Transplant Population
by Kahn, Jeffrey and Bang, Bo-Ram and Cook, Linda and Lee, Brian T and Harper, Tammy and Kim, Brian and Emamaullee, Juliet and Genyk, Yuri and Chopra, Shefali and Kanel, Gary and Jerome, Keith and Saito, Takeshi
Gastroenterology, ISSN 0016-5085, 05/2018, Volume 154, Issue 6, pp. S-1103 - S-1103
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10. Full Text Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling
by Kang, Young Jun and Bang, Bo-Ram and Han, Kyung Ho and Hong, Lixin and Shim, Eun-Jin and Ma, Jianhui and Lerner, Richard A and Otsuka, Motoyuki
Nature Communications, ISSN 2041-1723, 09/2015, Volume 6, Issue 1, p. 8371
The receptor-interacting protein kinase 3 (RIPK3) plays crucial roles in programmed necrosis and innate inflammatory responses. However, a little is known... 
NATURAL-KILLER-CELLS | ALPHA-GALACTOSYLCERAMIDE | MULTIDISCIPLINARY SCIENCES | PROGRAMMED NECROSIS | INNATE IMMUNE | NLRP3 INFLAMMASOME | MOLECULAR SWITCH | TNF-ALPHA | CYTOKINE EXPRESSION | T-CELLS | EXPERIMENTAL DISEASE-MODELS | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Neoplasm Transplantation | Dynamins - metabolism | Humans | Liver - immunology | Phosphoric Monoester Hydrolases - immunology | Melanoma, Experimental | HEK293 Cells | Tumor Necrosis Factor-alpha - immunology | Active Transport, Cell Nucleus | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Cytokines - immunology | Phosphoprotein Phosphatases | Signal Transduction | Jurkat Cells | NFATC Transcription Factors - metabolism | Inflammation | Mitochondria - metabolism | Blotting, Western | Mice, Knockout | Immunity, Cellular - immunology | Interleukin-4 - immunology | Dynamins - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Hepatocytes | Interferon-gamma - immunology | Mice | Phosphoric Monoester Hydrolases - metabolism | Natural Killer T-Cells - immunology | Liver | Crosstalk | Activation | Dephosphorylation | NF-AT protein | Kinases | Necrosis | Metastases | Proteins | Mitochondria | Cell activation | Clonal deletion | Phosphoglycerate mutase | Deletion | Translocation | Cytokines | Immune response (cell-mediated) | Pharmacology | Nuclear transport | Signaling | Damage detection | Protein kinase | Dynamin | Tumors | Guanosinetriphosphatase
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11. Full Text Inhibition of 4-1BBL-regulated TLR response in macrophages ameliorates endotoxin-induced sepsis in mice
: Innate immunity
by Bang, Bo Ram and Kim, Sang Jick and Yagita, Hideo and Croft, Michael and Kang, Young Jun
European Journal of Immunology, ISSN 0014-2980, 03/2015, Volume 45, Issue 3, pp. 886 - 892
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12. Full Text Organ system view of the hepatic innate immunity in HCV infection
by Bang, Bo‐Ram and Elmasry, Sandra and Saito, Takeshi
Journal of Medical Virology, ISSN 0146-6615, 12/2016, Volume 88, Issue 12, pp. 2025 - 2037
An orchestration of innate and adaptive immunity determines the infection outcome and whether the host achieves clearance or allows the pathogen to establish... 
viral hepatitis | Kupffer cell | hepatocyte | innate immunity | LSEC | HCV | dendritic cell | Dendritic cell | Viral hepatitis | Hepatocyte | Innate immunity | NATURAL-KILLER-CELLS | DOUBLE-STRANDED-RNA | LIVER ENDOTHELIAL-CELLS | NONSTRUCTURAL PROTEIN 5A | INTERFERON-LAMBDA | RIG-I | PLASMACYTOID DENDRITIC CELLS | GENETIC-VARIATION | VIROLOGY | C VIRUS-INFECTION | TOLL-LIKE RECEPTORS | Adaptive Immunity | Liver - virology | Signal Transduction | Hepacivirus - immunology | Dendritic Cells - immunology | Humans | Immunity, Innate | Interferons - immunology | Kupffer Cells - virology | Host-Pathogen Interactions | Hepatitis C - immunology | Liver - immunology | Immune Evasion | Virus Replication | Hepatocytes - virology | Hepacivirus - physiology | Dendritic Cells - virology | Hepatitis C virus | Health aspects | Hepatitis | Epidemiology | Immunology | Kupffer Cell | Innate Immunity | Dendritic Cell | Viral Hepatitis
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13. Full Text Tissue-specific regulation of p38α-mediated inflammation in Con A-induced acute liver damage
by Kang, Young Jun and Bang, Bo-Ram and Otsuka, Motoyuki and Otsu, Kinya
Journal of Immunology, ISSN 0022-1767, 05/2015, Volume 194, Issue 10, pp. 4759 - 4766
Because p38 alpha plays a critical role in inflammation, it has been an attractive target for the development of anti-inflammation therapeutics. However, p38... 
INDUCED HEPATITIS | CONCANAVALIN-A | IMMUNE-RESPONSE | ACTIVATED PROTEIN-KINASE | P38 | INJURY | KUPFFER CELLS | MICE | TNF-ALPHA | IMMUNOLOGY | T-CELLS | Immunohistochemistry | Liver Diseases - immunology | Concanavalin A - toxicity | Mitogen-Activated Protein Kinase 14 - immunology | Enzyme-Linked Immunosorbent Assay | Liver - metabolism | Mice, Inbred C57BL | Immunoblotting | Inflammation - immunology | Gene Knockout Techniques | Reverse Transcriptase Polymerase Chain Reaction | Inflammation - metabolism | Liver - immunology | Animals | Flow Cytometry | Mitogen-Activated Protein Kinase 14 - metabolism | T-Lymphocytes - metabolism | Natural Killer T-Cells - metabolism | Inflammation Mediators - metabolism | T-Lymphocytes - immunology | Mice | Liver Diseases - metabolism | Disease Models, Animal | Natural Killer T-Cells - immunology | Index Medicus | Abridged Index Medicus
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14. Full Text Retinoid regulation of antiviral innate immunity in hepatocytes
: Hepatology, Vol. XX, No. X, 2015
by Cho, Noell E and Bang, Bo-Ram and Gurung, Purnima and Li, Meng and Clemens, Dahn L and Underhill, T. Michael and James, Laura P and Chase, Jenifer R and Saito, Takeshi
Hepatology, ISSN 0270-9139, 06/2016, Volume 63, Issue 6, pp. 1783 - 1795
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15. Full Text IL-32[gamma] attenuates airway fibrosis by modulating the integrin-FAK signaling pathway in fibroblasts
by Hong, Gyong Hwa and Park, So-Young and Kwon, Hyouk-Soo and Bang, Bo-Ram and Lee, Jaechun and Kim, Sang-Yeob and Pack, Chan-Gi and Kim, Soohyun and Moon, Keun-Ai and Kim, Tae-Bum and Moon, Hee-Bom and Cho, You Sook
Respiratory Research, ISSN 1465-9921, 09/2018, Volume 19, Issue 1
Fibrosis in severe asthma often leads to irreversible organ dysfunction. However, the mechanism that regulates fibrosis remains poorly understood. Interleukin... 
Care and treatment | Pulmonary fibrosis | Interleukins | Fibroblasts | Physiological aspects | Development and progression | Genetic aspects | Research
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16. Full Text Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance
by Bang, BR and Li, M and Tsai, KN and Aoyagi, H and Lee, SA and Machida, K and Aizaki, H and Jung, JU and Ou, JHJ and Saito, T
JOURNAL OF VIROLOGY, ISSN 0022-538X, 04/2019, Volume 93, Issue 8
Retinoid (vitamin A) is an essential diet constituent that governs a broad range of biological processes. Its biologically active metabolite, all-trans... 
lipid droplet | all-trans retinoic acid | vitamin A | DENDRITIC CELLS | SREBP-1A MESSENGER-RNA | TRANSCRIPTION | ALPHA | LIVER X RECEPTOR | VITAMIN-A | cellular retinoic acid binding protein | INTERFERON | REPLICATION | VIROLOGY | hepatitis C virus | GENE-EXPRESSION | INNATE IMMUNITY
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17. Full Text Changes in Salmon (Oncorhynchus keta) Flesh Quality Following Ultra-High Pressure Treatment and 30 d of Chilled Storage
: Useful food preservation
by Park, Dae-Hun and Jung, Jong-Gi and Jung, Bo-Ram and Kim, Gyeyeop and Lee, Honggyun and Kim, Hyeon-A and Bang, Mi-Ae
Journal of Food Science, ISSN 0022-1147, 01/2015, Volume 80, Issue 1, pp. M142 - M146
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18. Inhibitory effects on melanin production in B16 melanoma cells of fallen pear
by Shin, Bo Yeon and Jung, Bo Ram and Jung, Jong Gi and Cho, Seung Sik and Bang, Mi Ae
Journal of the Korean Society of Food Science and Nutrition, ISSN 1226-3311, 03/2017, Volume 46, Issue 3, pp. 320 - 326
B16F10 melanoma cell | Mushroom tyrosinase | Fallen pear | Melanin | Tyrosinase
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19. Hepatic IFN-induced protein with tetratricopeptide repeats regulation of HCV infection
by Ishida, Yuji and Kakuni, Masakazu and Bang, Bo-Ram and Sugahara, Go and Lau, Daryl T.-Y and Tateno-Mukaidani, Chise and Li, Meng and Gale, Michael and Saito, Takeshi
Journal of Interferon and Cytokine Research, ISSN 1079-9907, 03/2019, Volume 39, Issue 3, pp. 133 - 146
Interferons (IFNs) suppress viral infection through the induction of >400 interferon-stimulated genes (ISGs). Among ISGs, IFN-induced protein with... 
hepatitis C virus | humanized liver chimeric mice | interferon stimulated genes | IFN-induced protein with tetratricopeptide repeats | ANTIVIRAL DEFENSES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERFERON-STIMULATED GENES | RIG-I | ALPHA | IMMUNOLOGY | CELL BIOLOGY | IL28B | REPLICATION | C VIRUS-INFECTION | CELL-CULTURE | SPONTANEOUS CLEARANCE | INNATE IMMUNITY | Initiation complex | Internal ribosome entry site | Liver | Genes | Translation initiation | Viruses | Infections | Genomes | Proteins | Hepatitis | Antiviral activity | Interferon | In vivo methods and tests | Hepatitis C virus | Hepatitis C | Viral infections
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20. Full Text Retinoid regulation of antiviral innate immunity in hepatocytes
by Cho, Noell E and Bang, Bo‐Ram and Gurung, Purnima and Li, Meng and Clemens, Dahn L and Underhill, T. Michael and James, Laura P and Chase, Jenifer R and Saito, Takeshi
Hepatology, ISSN 0270-9139, 06/2016, Volume 63, Issue 6, pp. 1783 - 1795
Persistent infection of hepatitis C virus (HCV) is one of the leading causes of end‐stage liver disease (ESLD), such as decompensated cirrhosis and liver... 
ACID | PROMYELOCYTIC LEUKEMIA | METABOLISM | ALDEHYDE DEHYDROGENASE | ALCOHOL-DEHYDROGENASE | LIVER | HEPATITIS-C-VIRUS | INTERFERON-STIMULATED GENES | ACETAMINOPHEN-PROTEIN ADDUCTS | GASTROENTEROLOGY & HEPATOLOGY | VITAMIN-A | Liver Failure - etiology | Cell Line | Ethanol - metabolism | Humans | Mice, Inbred C57BL | Gene Expression Regulation | Hepatitis C, Chronic - complications | Hepatocytes - metabolism | Hepatocytes - immunology | Immunity, Innate | Vitamin A - metabolism | Animals | Ethanol - adverse effects | Liver Diseases, Alcoholic - complications | Alcohol | Liver diseases | Dehydrogenases | Liver | Rodents
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