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Nature Medicine, ISSN 1078-8956, 11/2015, Volume 21, Issue 11, pp. 1326 - 1331
Mechanical allodynia, induced by normally innocuous low-threshold mechanical stimulation, represents a cardinal feature of neuropathic pain. Blockade or... 
MEDICINE, RESEARCH & EXPERIMENTAL | FLAGELLIN | NOCICEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TACTILE ALLODYNIA | INNATE | RATS | SPINAL-CORD | NERVE INJURY | CELL BIOLOGY | TOLL-LIKE RECEPTOR-5 | ITCH | PRIMARY SENSORY NEURONS | Lidocaine - pharmacology | Neuralgia - genetics | Capsaicin - pharmacology | Toll-Like Receptor 5 - genetics | Humans | Middle Aged | Neuralgia - metabolism | Male | Neurons - cytology | Ganglia, Spinal - cytology | Anesthetics, Local - pharmacology | Antineoplastic Agents - toxicity | Sensory System Agents - pharmacology | Flagellin - pharmacology | Paclitaxel - toxicity | Neuralgia - etiology | Nerve Fibers, Unmyelinated - drug effects | Adult | Female | Neurons - metabolism | Neurons - drug effects | Nerve Fibers, Myelinated - metabolism | Peripheral Nerve Injuries - complications | Hyperalgesia - metabolism | Nerve Fibers, Myelinated - drug effects | Mice, Knockout | Lidocaine - analogs & derivatives | Animals | Hyperalgesia - genetics | Hyperalgesia - etiology | Aged | Mice | Ganglia, Spinal - drug effects | Neurofilament Proteins - metabolism | Diabetic Neuropathies - complications | Ganglia, Spinal - metabolism | Genetically modified mice | Care and treatment | Pain | Dorsal root ganglia | Management | Research | TLR5 | Chronic pain | Pharmacology | Neurological disorders | Pain management | Immune system
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2018, Volume 128, Issue 8, pp. 3568 - 3582
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 12/2017, Volume 63, Issue 3, pp. 422 - 430
Journal Article
Pain, ISSN 0304-3959, 2011, Volume 152, Issue 5, pp. 1156 - 1164
Transient receptor potential ion channels (TRPs) expressed in the periphery sense and electrically transduce noxious stimuli to transmit the signals to the... 
Pain | TRPA1 | TRPV3 | Sensory neuron | Keratinocyte | Antinociception | Isopentenyl pyrophosphate | ACTIVATION | SENSITIVITY | NEUROSCIENCES | CLINICAL NEUROLOGY | BISPHOSPHONATES | RECEPTOR POTENTIAL CHANNELS | BIOSYNTHESIS | ANESTHESIOLOGY | SKIN | FARNESYL PYROPHOSPHATE | Inflammation - chemically induced | Acrolein - analogs & derivatives | Analgesics - pharmacology | Transient Receptor Potential Channels - antagonists & inhibitors | Calcium Channels - metabolism | Calcium - metabolism | Humans | Nerve Tissue Proteins - deficiency | Ganglia, Spinal - cytology | RNA, Messenger - metabolism | Transient Receptor Potential Channels - deficiency | Patch-Clamp Techniques - methods | Inflammation - complications | TRPV Cation Channels - metabolism | Transfection - methods | Pain - drug therapy | TRPV Cation Channels - antagonists & inhibitors | Freund's Adjuvant - adverse effects | Organophosphorus Compounds - pharmacology | Pain - etiology | Transient Receptor Potential Channels - metabolism | Calcium Channels - genetics | Disease Models, Animal | Hemiterpenes - pharmacology | Membrane Potentials - drug effects | Acrolein - pharmacology | Nerve Tissue Proteins - antagonists & inhibitors | RNA, Small Interfering - pharmacology | Cells, Cultured | Nerve Tissue Proteins - genetics | Mice, Inbred ICR | TRPV Cation Channels - genetics | Mice, Knockout | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Animals | Sensory Receptor Cells - drug effects | Transient Receptor Potential Channels - genetics | TRPA1 Cation Channel | Acrolein - therapeutic use | Mice | Calcium Channels - deficiency
Journal Article
The Journal of General Physiology, ISSN 0022-1295, 03/2009, Volume 133, Issue 3, pp. 257 - 262
Journal Article
The Journal of General Physiology, ISSN 0022-1295, 03/2009, Volume 133, Issue 3, p. 257
  Understanding the mechanism of peripheral pain sensation has progressed remarkably in recent years, in part thanks to the discovery of transient receptor... 
Proteins | Pain | Neurons | Ions | Pharmacology
Journal Article
Nature Communications, ISSN 2041-1723, 08/2016, Volume 7, Issue 1, p. 12531
Mechanisms of acute pain transition to chronic pain are not fully understood. Here we demonstrate an active role of beta-arrestin 2 (Arrb2) in regulating... 
NEUROPATHIC PAIN | MECHANICAL ALLODYNIA | CENTRAL SENSITIZATION | NOCICEPTIVE NEURONS | MORPHINE-TOLERANCE | MULTIDISCIPLINARY SCIENCES | PERIPHERAL NEUROPATHY | INFLAMMATORY PAIN | PRIMARY SENSORY NEURONS | SYNAPTIC PLASTICITY | DORSAL-HORN
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 11/2007, Volume 26, Issue 9, pp. 2516 - 2523
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 2013, Volume 33, Issue 33, pp. 13425 - 13430
It is well established that activation of NMDARs plays an essential role in spinal cord synaptic plasticity (i.e., central sensitization) and pain... 
CENTRAL SENSITIZATION | AMPA | GLUTAMATE RELEASE | RAT | PERIPHERY | NOCICEPTORS | MECHANISMS | RECEPTORS | NEUROSCIENCES | Brief Communications
Journal Article
Frontiers in pharmacology, ISSN 1663-9812, 2018, Volume 9, p. 412
Mechanisms of pain resolution are largely unclear. Increasing evidence suggests that specialized pro-resolving mediators (SPMs), derived from fish oil... 
Journal Article
Journal Article