X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (18) 18
ophthalmology (16) 16
microscopy, confocal (9) 9
cattle (8) 8
index medicus (7) 7
in vitro techniques (6) 6
mitochondria (6) 6
confocal laser scanning microscopy (5) 5
drug development (5) 5
rabbits (5) 5
biochemistry & molecular biology (4) 4
eye (4) 4
humans (4) 4
in-vitro (4) 4
injection (4) 4
intravitreal injection (4) 4
intravitreal injections (4) 4
lens, crystalline - drug effects (4) 4
macular degeneration (4) 4
oxidative stress (4) 4
rat lens (4) 4
cataract (3) 3
confocal microscopy (3) 3
crystalline lens (3) 3
disease models, animal (3) 3
fiber cells (3) 3
fluorescent dyes (3) 3
lens optics (3) 3
lens, crystalline - metabolism (3) 3
lens, crystalline - physiopathology (3) 3
male (3) 3
mitochondria - metabolism (3) 3
ocular toxicity (3) 3
ocular toxicology (3) 3
optical-quality (3) 3
pharmacokinetics (3) 3
pharmacology & pharmacy (3) 3
rats (3) 3
toxicology (3) 3
acridine orange (2) 2
analysis (2) 2
anterior segment syndrome (2) 2
apoptosis (2) 2
bovine lens (2) 2
bovine lens optical properties (2) 2
calcium (2) 2
cell survival (2) 2
cells, cultured (2) 2
contact lens (2) 2
contact lenses, hydrophilic (2) 2
cornea - drug effects (2) 2
dose-response relationship, drug (2) 2
endotoxin (2) 2
eye diseases (2) 2
fluoresceins (2) 2
in vitro toxicology (2) 2
inflammation (2) 2
lens (2) 2
lens, crystalline - physiology (2) 2
lens, crystalline - radiation effects (2) 2
membrane (2) 2
microscopy, confocal - methods (2) 2
mitochondria - drug effects (2) 2
mitochondria - ultrastructure (2) 2
modeling cortical cataractogenesis (2) 2
morphology (2) 2
multidisciplinary sciences (2) 2
ocular inflammatory response (2) 2
optics and photonics (2) 2
organ culture techniques (2) 2
original articles (2) 2
outbreak (2) 2
physiological aspects (2) 2
pigment epithelium of eye - radiation effects (2) 2
protein (2) 2
proteins (2) 2
refraction, ocular (2) 2
retina - pathology (2) 2
rhodamine 123 (2) 2
surfactants (2) 2
sutures (2) 2
time factors (2) 2
tissue reaction (2) 2
toxicity (2) 2
uv irradiation (2) 2
vitamin-e (2) 2
vitreous body - drug effects (2) 2
8-methoxypsoralen (1) 1
accommodation, ocular - physiology (1) 1
accommodation, ocular - radiation effects (1) 1
acid microspheres (1) 1
acridine orange - chemistry (1) 1
acridine-orange (1) 1
adenosine triphosphate - chemistry (1) 1
adjuvants, immunologic - toxicity (1) 1
adsorption (1) 1
aflibercept (1) 1
age (1) 1
age-related macular degeneration (1) 1
age-related-changes (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Drug Discovery Today, ISSN 1359-6446, 08/2019, Volume 24, Issue 8, pp. 1539 - 1550
The safety evaluation of ocular long-acting delivery (LAD) technologies is a nascent field. Here, we detail the challenges in assessing the safety of novel LAD... 
IN-VITRO | FLUOCINOLONE ACETONIDE IMPLANT | LATANOPROST CATIONIC EMULSION | DRUG-DELIVERY | RHESUS-MONKEYS | MACULAR EDEMA | INTRAOCULAR PHARMACOKINETICS | SINGLE INTRAVITREAL INJECTION | PLGA MICROSPHERES | PHARMACOLOGY & PHARMACY | TISSUE REACTION
Journal Article
Ophthalmology, ISSN 0161-6420, 2019, Volume 126, Issue 8, pp. 1141 - 1154
Purpose: To evaluate the safety and efficacy of the Port Delivery System with ranibizumab (PDS)for neovascular age-related macular degeneration... 
OPHTHALMOLOGY | VISUAL-ACUITY | AFLIBERCEPT | OUTCOMES | Macular degeneration | Clinical trials | Physiological aspects
Journal Article
Ophthalmology, ISSN 0161-6420, 08/2019, Volume 126, Issue 8, pp. 1141 - 1154
To evaluate the safety and efficacy of the Port Delivery System with ranibizumab (PDS) for neovascular age-related macular degeneration (nAMD) treatment. Phase... 
Journal Article
Journal Article
Retina (Philadelphia, Pa.), ISSN 0275-004X, 08/2019, p. 1
To develop an animal model of vitreous hemorrhage (VH) to explore the impact of surgical parameters on VH associated with insertion of the Port Delivery System... 
Journal Article
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 10/2019, Volume 60, Issue 13, pp. 4097 - 4108
PURPOSE. Investigate a significant, dose-related increase in IOP, leading to glaucomatous damage to the neuroretina and optic nerve following intravitreal... 
intraocular pressure | ANGIOGENESIS | TIE2 | drug development | RECEPTOR | ocular pharmacology | intravitreal injection | ANGIOPOIETIN-2 | SCHLEMMS CANAL INTEGRITY | MODELS | aqueous humor outflow homeostasis | OPHTHALMOLOGY | MUTATIONS | TEK | ocular toxicology
Journal Article
Journal of Ocular Pharmacology and Therapeutics, ISSN 1080-7683, 01/2018, Volume 34, Issue 1-2, pp. 204 - 213
Journal Article
Journal of Ocular Pharmacology and Therapeutics, ISSN 1080-7683, 05/2019, Volume 35, Issue 4, pp. 245 - 253
To characterize the inflammatory response and determine the no-observable-effect level (NOEL) in cynomolgus monkey eyes after intravitreal (ITV) injection of... 
drug development | intravitreal injection | ocular toxicology | endotoxin | INJECTION | UVEITIS | REACTIVITY | OPHTHALMOLOGY | PHARMACOLOGY & PHARMACY | ANTERIOR SEGMENT SYNDROME | OUTBREAK | OCULAR INFLAMMATORY RESPONSE
Journal Article
Current Eye Research, ISSN 0271-3683, 07/2013, Volume 38, Issue 7, pp. 751 - 760
Journal Article
Molecular Vision, ISSN 1090-0535, 2011, Volume 17, Issue 33, pp. 270 - 278
Journal Article
Journal Article
Journal Article