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The New England Journal of Medicine, ISSN 0028-4793, 08/2015, Volume 373, Issue 9, pp. 834 - 844
Patients with previously untreated pulmonary arterial hypertension who were randomly assigned to combination therapy with ambrisentan and tadalafil had a... 
INHALED ILOPROST | SURVIVAL | TRIAL | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | EPOPROSTENOL | COMBINATION THERAPY | HEART-FAILURE | DOUBLE-BLIND | BOSENTAN | Hypertension, Pulmonary - mortality | Double-Blind Method | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Hypertension, Pulmonary - physiopathology | Male | Hospitalization | Disease Progression | Tadalafil | Phenylpropionates - therapeutic use | Peptide Fragments - blood | Adult | Female | Phenylpropionates - adverse effects | Aged | Hypertension, Pulmonary - drug therapy | Drug Therapy, Combination | Carbolines - therapeutic use | Carbolines - adverse effects | Natriuretic Peptide, Brain - blood | Pyridazines - adverse effects | Pyridazines - therapeutic use | Symptomatology | Care and treatment | Usage | Analysis | Clinical trials | Dosage and administration | Pulmonary hypertension | Ambrisentan | Hypertension | Edema | Brain natriuretic peptide | Headache | Functional morphology | Pulmonary arteries | Lung diseases | Drug therapy | Patients | Clinical outcomes | Drug side effects | Assaigs clínics de medicaments | Efectes secundaris dels medicaments | Hipertensió pulmonar | Drug testing | Life Sciences | Human health and pathology | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Drugs, ISSN 0012-6667, 06/2009, Volume 69, Issue 9, pp. 1153 - 1171
Journal Article
Thorax, ISSN 0040-6376, 05/2011, Volume 66, Issue 5, pp. 430 - 437
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 08/2010, Volume 182, Issue 4, pp. 477 - 488
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2009, Volume 54, Issue 1, pp. S10 - S19
Inflammatory processes are prominent in various types of human and experimental pulmonary hypertension (PH) and are increasingly recognized as major pathogenic... 
Cardiovascular | Internal Medicine | growth factors | inflammation | pulmonary vascular remodeling | CARDIAC & CARDIOVASCULAR SYSTEMS | IMMUNODEFICIENCY-VIRUS-INFECTION | SARCOMA-ASSOCIATED HERPESVIRUS | ENDOTHELIAL-CELL APOPTOSIS | SYSTEMIC-SCLEROSIS | HEPATITIS-C VIRUS | ACTIVE ANTIRETROVIRAL THERAPY | ARTERIAL-HYPERTENSION | PLEXIFORM LESIONS | 5-HYDROXYTRYPTAMINE TRANSPORTER GENE | CONNECTIVE-TISSUE DISEASES | Chemokine CCL5 | Inflammation - pathology | Humans | Scleroderma, Systemic - pathology | Hypertension, Pulmonary - physiopathology | NFATC Transcription Factors - physiology | Chemokines, CX3C - physiology | Cytokines - physiology | Vascular Resistance - physiology | Animals | Scleroderma, Systemic - physiopathology | Antineoplastic Agents - pharmacology | Hypertension, Pulmonary - virology | Hypertension, Pulmonary - etiology | Hypertension, Pulmonary - pathology | Inflammation - physiopathology | Hypertension | Tyrosine | Medical colleges | Lung diseases, Obstructive | Pharmacogenetics | Micropollutants | Dendritic cells | Antibodies | Development and progression | Inflammation | HIV (Viruses) | T cells | Macrophages | Endothelium | Polymerase chain reaction | Viral antibodies | Messenger RNA | Viral proteins | Hepatitis C | Vascular endothelial growth factor | Growth factors | Tumors | Platelet-derived growth factor | Endothelial growth factors | B cells | Pulmonary hypertension | Biomedical research | Cytokines | Pulmonary arteries | Migration | Recruitment | Proteins | Angiogenesis | Lymphocytes | Human immunodeficiency virus--HIV | Medical prognosis | Cell cycle | Chemokines
Journal Article
Circulation, ISSN 0009-7322, 03/2016, Volume 133, Issue 9, pp. 859 - 871
Journal Article
Journal of Clinical Pathology, ISSN 0022-2593, 07/2003, Volume 56, Issue 7, p. 481
BackgroundMapping the genetic component of molecular mechanisms responsible for the reduced penetrance (RP) of rare disorders constitutes one of the most... 
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 2019, Volume 56, Issue 7, pp. 481 - 490
Background Mapping the genetic component of molecular mechanisms responsible for the reduced penetrance (RP) of rare disorders constitutes one of the most... 
heritable pulmonary arterial hypertension | linkage | reduced penetrance | genetic modifier | clinical genetics | BMPR2 | GENOTYPE | RECEPTOR | LOCUS | BLOOD-PRESSURE | FIDGETIN | SETS | GENETICS & HEREDITY | MUTATIONS | EXPRESSION | GENOME-WIDE ASSOCIATION
Journal Article