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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2416 - 18
Controlled macrophage differentiation and activation in the initiation and resolution of inflammation is crucial for averting progression to chronic... 
VISUALIZATION | NEUTROPHIL EXTRACELLULAR TRAPS | ACTIVATION | LUPUS NEPHRITIS | GELATINASE-A | CRYSTAL-STRUCTURE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | HUMAN INTERFERON-GAMMA | METALLOELASTASE | ANTAGONISTS | Kidney - pathology | Humans | Male | Matrix Metalloproteinase 12 - genetics | Thioglycolates - toxicity | Interferon-gamma - metabolism | Peritonitis - pathology | Signal Transduction - immunology | Proteolysis | Arthritis - immunology | Female | Macrophages - immunology | Disease Models, Animal | Lupus Nephritis - pathology | Cell Line | Arthritis - pathology | Macrophage Activation - immunology | Collagen - immunology | Mice, Inbred C57BL | THP-1 Cells | Lupus Nephritis - immunology | Peritonitis - chemically induced | Matrix Metalloproteinase 12 - metabolism | Peritonitis - immunology | Mice, Knockout | Matrix Metalloproteinase Inhibitors - pharmacology | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Biopsy | RAW 264.7 Cells | Mice | Primary Cell Culture | Macrophage Activation - drug effects | Lupus | Glomerulonephritis | Synovitis | Activation | Matrix metalloproteinase | Macrophages | Disease control | Nitric-oxide synthase | Lymphadenopathy | Chronic conditions | Cell activation | Negative feedback | Major histocompatibility complex | Systemic lupus erythematosus | γ-Interferon | Metalloproteinase | Autoimmune diseases | Stat1 protein | Peritonitis | Binding sites | Life Sciences
Journal Article
by Vennin, C and Melenec, P and Rouet, R and Nobis, M and Cazet, AS and Murphy, KJ and Herrmann, D and Reed, DA and Lucas, MC and Warren, SC and Elgundi, Z and Pinese, M and Kalna, G and Roden, D and Samuel, M and Zaratzian, A and Grey, ST and Da Silva, A and Leung, W and Mathivanan, S and Wang, YX and Braithwaite, AW and Christ, D and Benda, A and Parkin, A and Phillips, PA and Whitelock, JM and Gill, AJ and Sansom, OJ and Croucher, DR and Parker, BL and Pajic, M and Morton, JP and Cox, TR and Timpson, P and Johns, AL and Chantrill, LA and Chou, A and Steinmann, A and Arshi, M and Dwarte, T and Froio, D and Pereira, B and Ritchie, S and Chambers, CR and Metcalf, X and Waddell, N and Pearson, JV and Patch, AM and Nones, K and Newell, F and Mukhopadhyay, P and Addala, V and Kazakoff, S and Holmes, O and Leonard, C and Wood, S and Grimmond, SM and Hofmann, O and Christ, A and Bruxner, T and Samra, JS and Pavlakis, N and High, HA and Asghari, R and Merrett, ND and Pavey, D and Das, A and Cosman, PH and Ismail, K and O'Connnor, C and Stoita, A and Williams, D and Spigellman, A and Lam, VW and McLeod, D and Kirk, J and Kench, JG and Grimison, P and Cooper, CL and Sandroussi, C and Goodwin, A and Mead, RS and Tucker, K and Andrews, L and Texler, M and Forest, C and Epari, KP and Ballal, M and Fletcher, DR and Mukhedkar, S and Zeps, N and Beilin, M and Feeney, K and Nguyen, NQ and Ruszkiewicz, AR and Worthley, C and Chen, J and Brooke-Smith, ME and Papangelis, V and ... and APGI and Australian Pancreatic Genome Initiative (APGI)
NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3637 - 22
Journal Article
by Scarpa, Aldo and Chang, David K and Nones, Katia and Corbo, Vincenzo and Patch, Ann-Marie and Bailey, Peter and Lawlor, Rita T and Johns, Amber L and Miller, David K and Mafficini, Andrea and Rusev, Borislav and Scardoni, Maria and Antonello, Davide and Barbi, Stefano and Sikora, Katarzyna O and Cingarlini, Sara and Vicentini, Caterina and McKay, Skye and Quinn, Michael C.J and Bruxner, Timothy J.C and Christ, Angelika N and Harliwong, Ivon and Idrisoglu, Senel and McLean, Suzanne and Nourse, Craig and Nourbakhsh, Ehsan and Wilson, Peter J and Anderson, Matthew J and Fink, J. Lynn and Newell, Felicity and Waddell, Nick and Holmes, Oliver and Kazakoff, Stephen H and Leonard, Conrad and Wood, Scott and Xu, Qinying and Nagaraj, Shivashankar Hiriyur and Amato, Eliana and Dalai, Irene and Bersani, Samantha and Cataldo, Ivana and Dei Tos, Angelo P and Capelli, Paola and Davì, Maria Vittoria and Landoni, Luca and Malpaga, Anna and Miotto, Marco and Whitehall, Vicki L.J and Leggett, Barbara A and Harris, Janelle L and Harris, Jonathan and Jones, Marc D and Humphris, Jeremy and Chantrill, Lorraine A and Chin, Venessa and Nagrial, Adnan M and Pajic, Marina and Scarlett, Christopher J and Pinho, Andreia and Rooman, Ilse and Toon, Christopher and Wu, Jianmin and Pinese, Mark and Cowley, Mark and Barbour, Andrew and Mawson, Amanda and Humphrey, Emily S and Colvin, Emily K and Chou, Angela and Lovell, Jessica A and Jamieson, Nigel B and Duthie, Fraser and Gingras, Marie-Claude and Fisher, William E and Dagg, Rebecca A and Lau, Loretta M.S and Lee, Michael and Pickett, Hilda A and Reddel, Roger R and Samra, Jaswinder S and Kench, James G and Merrett, Neil D and Epari, Krishna and Nguyen, Nam Q and Zeps, Nikolajs and Falconi, Massimo and Simbolo, Michele and Butturini, Giovanni and Van Buren, George and Partelli, Stefano and Fassan, Matteo and Khanna, Kum Kum and Gill, Anthony J and Wheeler, David A and Gibbs, Richard A and Musgrove, Elizabeth A and Bassi, Claudio and Tortora, Giampaolo and Pederzoli, Paolo and Pearson, John V and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 03/2017, Volume 543, Issue 7643, pp. 65 - 71
The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to more sensitive detection methods, and this increase is creating challenges... 
MOLECULAR SUBTYPES | MUTATIONAL PROCESSES | TRANSLOCATION | SUPPRESSOR | PROTEIN | PATHWAY GENES | MULTIDISCIPLINARY SCIENCES | MTOR PATHWAY | TP53 MUTATIONS | CANCER | EWING SARCOMA | Genetic aspects | Nucleotide sequencing | Pancreatic cancer | Methods | DNA sequencing | Genes | Biomarkers | Genomes | Mutation | Signatures | Patients | Tumors | Index Medicus
Journal Article
by Waddell, Nicola and Pajic, Marina and Patch, Ann-Marie and Chang, David K and Kassahn, Karin S and Bailey, Peter and Johns, Amber L and Miller, David and Nones, Katia and Quek, Kelly and Quinn, Michael C. J and Robertson, Alan J and Fadlullah, Muhammad Z. H and Bruxner, Tim J. C and Christ, Angelika N and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourse, Craig and Nourbakhsh, Ehsan and Wani, Shivangi and Wilson, Peter J and Markham, Emma and Cloonan, Nicole and Anderson, Matthew J and Fink, J. Lynn and Holmes, Oliver and Kazakoff, Stephen H and Leonard, Conrad and Newell, Felicity and Poudel, Barsha and Song, Sarah and Taylor, Darrin and Waddell, Nick and Wood, Scott and Xu, Qinying and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Lee, Hong C and Jones, Marc D and Nagrial, Adnan M and Humphris, Jeremy and Chantrill, Lorraine A and Chin, Venessa and Steinmann, Angela M and Mawson, Amanda and Humphrey, Emily S and Colvin, Emily K and Chou, Angela and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Pettitt, Jessica A and Merrett, Neil D and Toon, Christopher and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Jamieson, Nigel B and Graham, Janet S and Niclou, Simone P and Bjerkvig, Rolf and Grützmann, Robert and Aust, Daniela and Hruban, Ralph H and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Falconi, Massimo and Zamboni, Giuseppe and Tortora, Giampaolo and Tempero, Margaret A and Gill, Anthony J and Eshleman, James R and Pilarsky, Christian and Scarpa, Aldo and Musgrove, Elizabeth A and Pearson, John V and Biankin, Andrew V and Grimmond, Sean M and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7540, pp. 495 - 501
Journal Article
by Bailey, Peter and Chang, David K and Nones, Katia and Johns, Amber L and Patch, Ann-Marie and Gingras, Marie-Claude and Miller, David K and Christ, Angelika N and Bruxner, Tim J. C and Quinn, Michael C and Nourse, Craig and Murtaugh, L. Charles and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourbakhsh, Ehsan and Wani, Shivangi and Fink, Lynn and Holmes, Oliver and Chin, Venessa and Anderson, Matthew J and Kazakoff, Stephen and Leonard, Conrad and Newell, Felicity and Waddell, Nick and Wood, Scott and Xu, Qinying and Wilson, Peter J and Cloonan, Nicole and Kassahn, Karin S and Taylor, Darrin and Quek, Kelly and Robertson, Alan and Pantano, Lorena and Mincarelli, Laura and Sanchez, Luis N and Evers, Lisa and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Jones, Marc D and Colvin, Emily K and Nagrial, Adnan M and Humphrey, Emily S and Chantrill, Lorraine A and Mawson, Amanda and Humphris, Jeremy and Chou, Angela and Pajic, Marina and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Lovell, Jessica A and Merrett, Neil D and Toon, Christopher W and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Moran-Jones, Kim and Jamieson, Nigel B and Graham, Janet S and Duthie, Fraser and Oien, Karin and Hair, Jane and Grützmann, Robert and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Rusev, Borislav and Capelli, Paola and Salvia, Roberto and Tortora, Giampaolo and Mukhopadhyay, Debabrata and Petersen, Gloria M and Munzy, Donna M and Fisher, William E and Karim, Saadia A and Eshleman, James R and Hruban, Ralph H and Pilarsky, Christian and Morton, Jennifer P and Sansom, Owen J and Scarpa, Aldo and Musgrove, Elizabeth A and Bailey, Ulla-Maja Hagbo and Hofmann, Oliver and Sutherland, Robert L and Wheeler, David A and Gill, Anthony J and Gibbs, Richard A and Pearson, John V and Waddell, Nicola and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7592, pp. 47 - 52
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-beta,... 
PATHWAYS | METASTASIS | DUCTAL ADENOCARCINOMA | PACKAGE | MULTIDISCIPLINARY SCIENCES | TUMOR | MUTATIONS | DIFFERENTIATION | Pancreatic Neoplasms - metabolism | Prognosis | Hepatocyte Nuclear Factor 3-beta - genetics | Genomics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Hepatocyte Nuclear Factor 3-gamma - genetics | Gene Regulatory Networks | Histone Demethylases - genetics | Tumor Suppressor Protein p53 - genetics | Carcinoma, Pancreatic Ductal - genetics | DNA Methylation | Tumor Suppressor Proteins - genetics | Carcinoma, Pancreatic Ductal - classification | Trans-Activators - genetics | Pancreatic Neoplasms - classification | Transcription, Genetic | Nuclear Proteins - genetics | Carcinoma, Pancreatic Ductal - immunology | Genes, Neoplasm - genetics | Basic Helix-Loop-Helix Transcription Factors - genetics | Pancreatic Neoplasms - pathology | Zebrafish Proteins | Pancreatic Neoplasms - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Carcinoma, Pancreatic Ductal - pathology | Genome, Human - genetics | Homeodomain Proteins - genetics | Animals | Pancreatic Neoplasms - immunology | Survival Analysis | Cell Line, Tumor | Mice | Physiological aspects | Pancreatic cancer | Methods | Genes | Genomes | Mutation | Gene expression | Tumors
Journal Article
by Pérez-Mancera, Pedro A and Rust, Alistair G and Van Der Weyden, Louise and Kristiansen, Glen and Li, Allen and Sarver, Aaron L and Silverstein, Kevin A. T and Grützmann, Robert and Aust, Daniela and Rümmele, Petra and Knösel, Thomas and Herd, Colin and Stemple, Derek L and Kettleborough, Ross and Brosnan, Jacqueline A and Li, Ang and Morgan, Richard and Knight, Spencer and Yu, Jun and Stegeman, Shane and Collier, Lara S and Ten Hoeve, Jelle J and De Ridder, Jeroen and Klein, Alison P and Goggins, Michael and Hruban, Ralph H and Chang, David K and Biankin, Andrew V. Wessels and Grimmond, Sean M and Wessels, Lodewyk F. A and Wood, Stephen A and Iacobuzio-Donahue, Christine A and Pilarsky, Christian and Largaespada, David A and Adams, David J and Tuveson, David A and Bienkin, Andrew V and Johns, Amber L and Mawson, Amanda and Cheng, David K and Brancato, Mary-Anne L and Rowe, Sarah J and Simpson, Skye L and Martyn-Smith, Mona and Chantrill, Lorraine A and Chin, Venessa T and Chou, Angela and Cowley, Mark J and Humphris, Jeremy L and Jones, Marc D and Scott Mead, R and Nagrial, Adnan M and Pajic, Marina and Pettit, Jessica and Pinese, Mark and Rooman, Ilse and Wu, Jianmin and Daly, Roger J and Musgrove, Elizabeth A and Sutherland, Robert L and Grimond, Sean M and Waddell, Nicola and Kassahn, Karin S and Miller, David K and Wilson, Peter J and Patch, Ann-Marie and Song, Sarah and Harliwong, Ivon and Idrisoglu, Senel and Nourse, Craig and Nourbakhsh, Ehsan and Manning, Suzanne and Wani, Shivangi and Gongora, Milena and Anderson, Matthew and Holmes, Oliver and Leonard, Conrad and Taylor, Darrin and Wood, Scott and Xu, Christina and Nones, Katia and Lynn Fink, J and Christ, Angelika and Bruxner, Tim and Cloonan, Nicole and Newell, Felicity and Pearson, John V and Samra, Jaswinder S and Gill, Anthony J and Pavlakis, Nick and Guminski, Alex and Toon, Christopher and Blankin, Andrew V and Asghari, Ray and Merrett, Neil D and Pavey, Darren A and Das, Amithabad and Cosman, Peter H and Ismail, Kasim and O'Connor, Chelsie and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 06/2012, Volume 486, Issue 7402, pp. 266 - 270
Journal Article