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Nature, ISSN 0028-0836, 07/2009, Volume 460, Issue 7254, pp. 466 - 467
[...] a SNP in the promoter of MDM2, which encodes a major p53 inhibitor, alters p53 levels and affects the age at which people get certain tumours and the... 
Proteins | Regulation | DNA damage | Apoptosis | Cancer | Tumors
Journal Article
Brain, ISSN 0006-8950, 6/2009, Volume 132, Issue 6, pp. 1601 - 1612
Journal Article
Aging, ISSN 1945-4589, 2015, Volume 7, Issue 10, pp. 744 - 745
Journal Article
Transcription, ISSN 2154-1264, 03/2013, Volume 4, Issue 2, pp. 67 - 71
Journal Article
International Journal of Developmental Biology, ISSN 0214-6282, 2004, Volume 48, Issue 2-3, pp. 149 - 156
Journal Article
BMC Developmental Biology, ISSN 1471-213X, 03/2005, Volume 5, Issue 1, pp. 6 - 6
Journal Article
Mechanisms of Development, ISSN 0925-4773, 2001, Volume 101, Issue 1, pp. 263 - 265
Journal Article
Genes, ISSN 2073-4425, 02/2017, Volume 8, Issue 2, p. 82
MDM4, an essential negative regulator of the P53 tumor suppressor, is frequently overexpressed in cancer cells that harbor a wild-type P53. By a mechanism... 
MDM2 | Alternative splicing | Isoform | MDM4 | P53 | DOMAIN | alternative splicing | p53 | PRE-MESSENGER-RNA | CELL-DEATH | INHIBITION | IN-VIVO | THERAPEUTIC TARGET | BCL-X | GENETICS & HEREDITY | MICE | P53 ACTIVITY | EXPRESSION | isoform | Life Sciences | Human health and pathology | alternative splicing
Journal Article