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by Davies, Gail and Lam, M and Harris, Sarah and Trampush, J.W and Luciano, Michelle and Hill, W.D and Hagenaars, Saskia and Ritchie, S.J and Marioni, Riccardo and Fawns-Ritchie, C and Liewald, D.C.M and Okely, J.A and Ahola-Olli, A.V and Barnes, C.L.K and Bertram, Lars and Bis, Joshua and Burdick, K.E and Christoforou, Anea and Derosse, P and Djurovic, Srdjan and Espeseth, Thomas and Giakoumaki, S and Giddaluru, Sudheer and Gustavson, D.E and Hayward, Caroline and Hofer, Edith and Ikram, Arfan and Karlsson, Robert and Knowles, E and Lahti, Jari and Leber, Isabelle and Li, S and Mather, R and Melle, Ingrid and Morris, D and Oldmeadow, Christopher and Palviainen, T and Payton, Antony and Pazoki, Raha and Petrovic, Katja and Reynolds, C and Sargurupremraj, M and Scholz, Markus and Smith, Jennifer A and Smith, Albert and Terzikhan, Natalie and Thalamuthu, Anbupalam and Trompet, Stella and Lee, Sven and Ware, Erin B and Windham, B Gwen and Wright, M.J and Yang, J and Yu, J and Ames, David and Amin, Najaf and Amouyel, Philippe and Aneassen, Ole and Armstrong, Nicola J and Assareh, A.A and Attia, John and Attix, D and Avramopoulos, D and Bennett, David and Böhmer, Marcel and Boyle, P.A and Brodaty, Henry and Campbell, Harry and Cannon, T.D and Cirulli, E.T and Congdon, E and Conley, E.D and Corley, J and Cox, Simon R and Dale, Anders and Dehghan, Abbas and Dick, D and Dickinson, D and Hagen, Knut and Evangelou, Evangelos and Faul, Jessica D and Ford, Ian and Freimer, N.A and Gao, H and Giegling, Ina and Gillespie, N.A and Gordon, Scott D and Gottesman, Rebecca and Griswold, Michael and Gudnason, V and Harris, Tamara and Hartmann, Annette M and Hatzimanolis, A and Heiss, Gerardo and Holliday, Elizabeth and Joshi, Peter and Kähönen, Mika and Kardia, S.L.R and Karlsson, I and Kleineidam, L and ...
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2098 - 16
textabstractGeneral cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine... 
COMMON VARIANTS | METAANALYSIS | REACTION-TIME | PROCESSING SPEED | MULTIDISCIPLINARY SCIENCES | INTELLIGENCE DIFFERENCES | SCHIZOPHRENIA | DCDC2 | DISCOVERY | GENOME-WIDE ASSOCIATION | REVEALS | Multifactorial Inheritance - genetics | Genetic Predisposition to Disease | Humans | Middle Aged | Genetic Loci - genetics | Neurodegenerative Diseases - genetics | Neurodevelopmental Disorders - genetics | Reaction Time - genetics | Young Adult | Mental Disorders - genetics | Adolescent | Aged, 80 and over | Cognition - physiology | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Hypertension | Brain | Cognitive ability | Genomes | Gene expression | Neurodevelopmental disorders | Loci | Consortia | Illnesses | Mathematical analysis | Reaction time | Heritability | Gene loci | Polygenic inheritance | brain cortex | Medical and Health Sciences | Medicin och hälsovetenskap | major clinical study | osteoarthritis | Article | heart infarction | Klinisk medicin | lung cancer | identification method | longevity | grip strength | angina pectoris | genetic correlation | human | major depression | Neurologi | cognition | data set | aged | brain | gene locus | Clinical Medicine | Neurology | genome | vision | genetic analysis | controlled study | response time | adolescent | nervous system disorder | adult | hypertension | gene expression
Journal Article
by Joshi, Peter and Pirastu, Nicola and Kentistou, K.A and Fischer, Krista and Hofer, Edith and Schraut, K.E and Clark, D.W and Nutile, T and Barnes, C.L.K and Timmers, P.R.H.J and Shen, X and Gandin, Ilaria and McDaid, A.F and Hansen, T.F and Gordon, Scott D and Giulianini, Franco and Boutin, Thibaud and Abdellaoui, Abdel and Zhao, Wei and Medina-Gomez, Carolina and Bartz, Traci M and Trompet, Stella and Lange, Leslie and Raffield, L and Spek, Ashley and Galesloot, Tessel and Proitsi, P and Yanek, Lisa and Bielak, Lawrence F and Payton, Antony and Murgia, Daniela and Concas, Maria Pina and Biino, Ginevra and Tajuddin, S.M and Seppälä, Ilkka and Amin, N and Boerwinkle, E and Børglum, A.D and Campbell, Archie and Demerath, Ellen and Demuth, Ilja and Faul, Jessica D and Ford, Ian and Gialluisi, A and Gögele, Martin and Graff, Maud J.L and Hingorani, Aroon and Hottenga, Jouke Jan and Hougaard, David and Hurme, M.A and Ikram, Kamran and Jylhä, M and Kuh, D and Ligthart, Lannie and Lill, Christina and Lindenberger, Ulman and Lumley, Thomas and Mägi, Reedik and Marques-Vidal, Peo and Medland, Sarah and Milani, Lili and Nagy, R and Ollier, William and Peyser, Patricia A and Pramstaller, Peter Paul and Ridker, Paul and Rivadeneira, F and Ruggiero, D and Saba, Yasaman and Schmidt, Reinhold and Schmidt, Helena and Slagboom, Eline and Smith, B.H and Smith, Jennifer A and Sotoodehnia, Nona and Steinhagen-Thiessen, Elisabeth and Rooij, Frank and Verbeek, A.L.M and Vermeulen, Sita and Vollenweider, Peter and Wang, Y and Werge, Thomas and Whitfield, John B and Zonderman, A.B and Lehtimäki, Terho and Evans, Michele and Pirastu, Mario and Fuchsberger, Christian and Bertram, Lars and Pendleton, Neil and Kardia, S.L.R and Ciullo, M and Becker, Diane and Wong, A and Psaty, Bruce M and Duijn, Cornelia and Wilson, James and Jukema, Jan Wouter and Kiemeney, Bart and Uitterlinden, Ané and ...
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 910 - 13
Journal Article
by Clark, D.W and Okada, Y and Moore, K.H.S and Mason, D and Pirastu, N and Gandin, Ilaria and Mattsson, Hannele and Barnes, C.L.K and Lin, K and Zhao, J.H and Deelen, Patrick and Rohde, Rebecca and Schurmann, Claudia and Guo, Xiuqing and Giulianini, Franco and Zhang, W and Medina-Gomez, Carolina and Karlsson, R and Bao, Y and Bartz, T.M and Baumbach, Clemens and Biino, Ginevra and Bixley, M.J and Brumat, M and Chai, J.-F and Corre, Tanguy and Cousminer, Diana and Dekker, A.M and Eccles, D.A and Eijk, Kristel and Fuchsberger, C and Gao, H and Germain, Marine and Gordon, Scott D and de Haan, H.G and Harris, Sarah and Hofer, Edith and Huerta-Chagoya, Alicia and Igartua, C and Jansen, Iris and Jia, Y and Kacprowski, Tim and Karlsson, T and Kleber, Marcus and Li, S.A and Li-Gao, R and Mahajan, Anubha and Matsuda, K and Meidtner, Karina and Meng, W and Montasser, May E and Most, Peter and Munz, M and Nutile, T and Palviainen, T and Prasad, G and Prasad, R.B and Priyanka, T.D.S and Rizzi, F and Salvi, E and Sapkota, B.R and Shriner, Daniel and Skotte, L and Smart, M.C and Smith, Albert and Spek, Ashley and Spracklen, C.N and Strawbridge, Rona and Tajuddin, S.M and Trompet, Stella and Turman, C and Verweij, N and Viberti, C and Wang, L and Warren, Helen and Wootton, R.E and Yanek, Lisa and Yao, Jie and Yousri, N.A and Zhao, W and Adeyemo, A.A and Afaq, S and Aguilar-Salinas, C.A and Akiyama, M and Albert, M.L and Allison, M.A and Alver, Maris and Aung, Tin and Azizi, Joshan and Bentley, Amy and Boeing, Heiner and Boerwinkle, Eric and Borja, J.B and Borst, Gert and Bottinger, Erwin and Broer, L and Campbell, H and Chanock, Stephen and Chee, M.-L and Chen, G and ... and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden and et al
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1
textabstractIn many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the... 
Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Joshi, P.K and Pirastu, N and Kentistou, K.A and Fischer, K and Hofer, E and Schraut, K.E and Clark, D.W and Nutile, T and Barnes, C.L.K and Timmers, P and Shen, X and Gandin, I and McDaid, A.F and Hansen, T.F and Gordon, S.D.S and Giulianini, F and Boutin, T.S and Abdellaoui, A and Zhao, W and Medina-Gomez, C and Bartz, T.M and Trompet, S and Lange, L.A and Raffield, L and Spek, A van der and Galesloot, T.E and Proitsi, P and Yanek, L.R and Bielak, L.F and Payton, A and Murgia, F and Concas, M.P and Biino, G and Tajuddin, S.M and Seppala, I and Amin, N and Boerwinkle, E and Borglum, A.D and Campbell, A and Demerath, E.W and Demuth, I and Faul, J.D and Ford, I and Gialluisi, A and Gogele, M and Graff, M and Hingorani, A and Hottenga, J.J and Hougaard, D.M and Hurme, M.A and Ikram, M.A and Jylha, M and Kuh, D and Ligthart, L and Lill, C.M and Lindenberger, U and Lumley, T and Magi, R and Marques-Vidal, P and Medland, S.E and Milani, L and Nagy, R and Ollier, W.E and Peyser, P.A and Pramstaller, P.P and Ridker, P.M and Rivadeneira, F and Ruggiero, D and Saba, Y and Schmidt, R and Schmidt, H and Slagboom, P.E and Smith, B.H and Smith, J.A and Sotoodehnia, N and Steinhagen-Thiessen, E and Rooij, F.J. van and Verbeek, A.L and Vermeulen, S.H and Vollenweider, P and Wang, Y and Werge, T and Whitfield, J.B and Zonderman, A.B and Lehtimaki, T and Evans, M.K and Pirastu, M and Fuchsberger, C and Bertram, L and Pendleton, N and Kardia, S.L and Ciullo, M and Becker, D.M and Wong, A and Psaty, B.M and Duijn, C.M. van and Wilson, J.G and Jukema, J.W and Kiemeney, L.A and Uitterlinden, A.G
Nature Communications, ISSN 2041-1723, 2017, Volume 8
Genomic analysis of longevity offers the potential to illuminate the biology of human aging. Here, using genome-wide association meta-analysis of 606,059... 
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 28, pp. 10083 - 10088
Journal Article
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