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1. Full Text Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
by Davies, Gail and Lam, M and Harris, Sarah and Trampush, J.W and Luciano, Michelle and Hill, W.D and Hagenaars, Saskia and Ritchie, S.J and Marioni, Riccardo and Fawns-Ritchie, C and Liewald, D.C.M and Okely, J.A and Ahola-Olli, A.V and Barnes, C.L.K and Bertram, Lars and Bis, Joshua and Burdick, K.E and Christoforou, Anea and Derosse, P and Djurovic, Srdjan and Espeseth, Thomas and Giakoumaki, S and Giddaluru, Sudheer and Gustavson, D.E and Hayward, Caroline and Hofer, Edith and Ikram, Arfan and Karlsson, Robert and Knowles, E and Lahti, Jari and Leber, Isabelle and Li, S and Mather, R and Melle, Ingrid and Morris, D and Oldmeadow, Christopher and Palviainen, T and Payton, Antony and Pazoki, Raha and Petrovic, Katja and Reynolds, C and Sargurupremraj, M and Scholz, Markus and Smith, Jennifer A and Smith, Albert and Terzikhan, Natalie and Thalamuthu, Anbupalam and Trompet, Stella and Lee, Sven and Ware, Erin B and Windham, B Gwen and Wright, M.J and Yang, J and Yu, J and Ames, David and Amin, Najaf and Amouyel, Philippe and Aneassen, Ole and Armstrong, Nicola J and Assareh, A.A and Attia, John and Attix, D and Avramopoulos, D and Bennett, David and Böhmer, Marcel and Boyle, P.A and Brodaty, Henry and Campbell, Harry and Cannon, T.D and Cirulli, E.T and Congdon, E and Conley, E.D and Corley, J and Cox, Simon R and Dale, Anders and Dehghan, Abbas and Dick, D and Dickinson, D and Hagen, Knut and Evangelou, Evangelos and Faul, Jessica D and Ford, Ian and Freimer, N.A and Gao, H and Giegling, Ina and Gillespie, N.A and Gordon, Scott D and Gottesman, Rebecca and Griswold, Michael and Gudnason, V and Harris, Tamara and Hartmann, Annette M and Hatzimanolis, A and Heiss, Gerardo and Holliday, Elizabeth and Joshi, Peter and Kähönen, Mika and Kardia, S.L.R and Karlsson, I and Kleineidam, L and ...
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2098 - 16
textabstractGeneral cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine... 
COMMON VARIANTS | METAANALYSIS | REACTION-TIME | PROCESSING SPEED | MULTIDISCIPLINARY SCIENCES | INTELLIGENCE DIFFERENCES | SCHIZOPHRENIA | DCDC2 | DISCOVERY | GENOME-WIDE ASSOCIATION | REVEALS | Multifactorial Inheritance - genetics | Genetic Predisposition to Disease | Humans | Middle Aged | Genetic Loci - genetics | Neurodegenerative Diseases - genetics | Neurodevelopmental Disorders - genetics | Reaction Time - genetics | Young Adult | Mental Disorders - genetics | Adolescent | Aged, 80 and over | Cognition - physiology | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Hypertension | Brain | Cognitive ability | Genomes | Gene expression | Neurodevelopmental disorders | Loci | Consortia | Illnesses | Mathematical analysis | Reaction time | Heritability | Gene loci | Polygenic inheritance | brain cortex | Medical and Health Sciences | Medicin och hälsovetenskap | major clinical study | osteoarthritis | Article | heart infarction | Klinisk medicin | lung cancer | identification method | longevity | grip strength | angina pectoris | genetic correlation | human | major depression | Neurologi | cognition | data set | aged | brain | gene locus | Clinical Medicine | Neurology | genome | vision | genetic analysis | controlled study | response time | adolescent | nervous system disorder | adult | hypertension | gene expression
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2. Full Text Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
by Joshi, Peter and Pirastu, Nicola and Kentistou, K.A and Fischer, Krista and Hofer, Edith and Schraut, K.E and Clark, D.W and Nutile, T and Barnes, C.L.K and Timmers, P.R.H.J and Shen, X and Gandin, Ilaria and McDaid, A.F and Hansen, T.F and Gordon, Scott D and Giulianini, Franco and Boutin, Thibaud and Abdellaoui, Abdel and Zhao, Wei and Medina-Gomez, Carolina and Bartz, Traci M and Trompet, Stella and Lange, Leslie and Raffield, L and Spek, Ashley and Galesloot, Tessel and Proitsi, P and Yanek, Lisa and Bielak, Lawrence F and Payton, Antony and Murgia, Daniela and Concas, Maria Pina and Biino, Ginevra and Tajuddin, S.M and Seppälä, Ilkka and Amin, N and Boerwinkle, E and Børglum, A.D and Campbell, Archie and Demerath, Ellen and Demuth, Ilja and Faul, Jessica D and Ford, Ian and Gialluisi, A and Gögele, Martin and Graff, Maud J.L and Hingorani, Aroon and Hottenga, Jouke Jan and Hougaard, David and Hurme, M.A and Ikram, Kamran and Jylhä, M and Kuh, D and Ligthart, Lannie and Lill, Christina and Lindenberger, Ulman and Lumley, Thomas and Mägi, Reedik and Marques-Vidal, Peo and Medland, Sarah and Milani, Lili and Nagy, R and Ollier, William and Peyser, Patricia A and Pramstaller, Peter Paul and Ridker, Paul and Rivadeneira, F and Ruggiero, D and Saba, Yasaman and Schmidt, Reinhold and Schmidt, Helena and Slagboom, Eline and Smith, B.H and Smith, Jennifer A and Sotoodehnia, Nona and Steinhagen-Thiessen, Elisabeth and Rooij, Frank and Verbeek, A.L.M and Vermeulen, Sita and Vollenweider, Peter and Wang, Y and Werge, Thomas and Whitfield, John B and Zonderman, A.B and Lehtimäki, Terho and Evans, Michele and Pirastu, Mario and Fuchsberger, Christian and Bertram, Lars and Pendleton, Neil and Kardia, S.L.R and Ciullo, M and Becker, Diane and Wong, A and Psaty, Bruce M and Duijn, Cornelia and Wilson, James and Jukema, Jan Wouter and Kiemeney, Bart and Uitterlinden, Ané and ...
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 910 - 13
textabstractGenomic analysis of longevity offers the potential to illuminate the biology of human aging. Here, using genome-wide association meta-analysis of... 
SURVIVAL | INDIVIDUALS | POPULATION | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY LOCI | RISK | GENETIC-VARIANTS | APOE | BLOOD-PRESSURE | AGE | Body Mass Index | Lung Neoplasms - genetics | Smoking - adverse effects | Coronary Disease - blood | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Life Style | HLA-DRB1 Chains - genetics | Lipoproteins, HDL - blood | Obesity - complications | Humans | Coronary Disease - etiology | Longevity - genetics | HLA-DQ alpha-Chains - genetics | Obesity - genetics | Socioeconomic Factors | Education | Alleles | Insulin Resistance - genetics | Lung Neoplasms - blood | Polymorphism, Single Nucleotide | Lipoprotein(a) - genetics | Body fat | DQA1 protein | Lung cancer | Parents | Cardiovascular disease | Genomes | Body mass index | Apolipoprotein E | Drb1 protein | Aging | Heart diseases | Lipoproteins (high density) | FOXO3 protein | Genomic analysis | Coronary artery | Longevity | Cigarettes | Cigarette smoking | Insulin | Coronary artery disease | Cholesterol | Educational attainment | Genetic variance | Life span | Body mass | Histocompatibility antigen HLA | Smoking
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3. Full Text Associations of autozygosity with a broad range of human phenotypes
by Clark, D.W and Okada, Yuya and Moore, K.H.S and Mason, Deborah and Pirastu, Nicola and Gandin, I and Mattsson, H and Barnes, C.L.K and Lin, Kuang and Zhao, Jing Hua and Deelen, Patrick and Rietveld, Niels and Wilson, James F and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Molekylär evolution and Institutionen för cell- och molekylärbiologi and Medicinsk genetik och genomik and Teknisk-naturvetenskapliga vetenskapsområdet and Biologiska sektionen and Uppsala universitet
Nature Communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 4957 - 17
textabstractIn many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the... 
HOMOZYGOSITY | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | INBREEDING DEPRESSION | LOCI | RUNS | FERTILITY | Genetic variance | Progeny | Reproduction | Phenotypes | Inbreeding depression | Offspring | Fertility | Breeding success | Inbreeding | Social factors | Children | Homozygosity | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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4. Full Text Associations of autozygosity with a broad range of human phenotypes
by Clark, D.W and Okada, Y and Moore, K.H.S and Mason, D and Pirastu, N and Gandin, Ilaria and Mattsson, Hannele and Barnes, C.L.K and Lin, K and Zhao, J.H and Deelen, Patrick and Rohde, Rebecca and Schurmann, Claudia and Guo, Xiuqing and Giulianini, Franco and Zhang, W and Medina-Gomez, Carolina and Karlsson, R and Bao, Y and Bartz, T.M and Baumbach, Clemens and Biino, Ginevra and Bixley, M.J and Brumat, M and Chai, J.-F and Corre, Tanguy and Cousminer, Diana and Dekker, A.M and Eccles, D.A and Eijk, Kristel and Fuchsberger, C and Gao, H and Germain, Marine and Gordon, Scott D and de Haan, H.G and Harris, Sarah and Hofer, Edith and Huerta-Chagoya, Alicia and Igartua, C and Jansen, Iris and Jia, Y and Kacprowski, Tim and Karlsson, T and Kleber, Marcus and Li, S.A and Li-Gao, R and Mahajan, Anubha and Matsuda, K and Meidtner, Karina and Meng, W and Montasser, May E and Most, Peter and Munz, M and Nutile, T and Palviainen, T and Prasad, G and Prasad, R.B and Priyanka, T.D.S and Rizzi, F and Salvi, E and Sapkota, B.R and Shriner, Daniel and Skotte, L and Smart, M.C and Smith, Albert and Spek, Ashley and Spracklen, C.N and Strawbridge, Rona and Tajuddin, S.M and Trompet, Stella and Turman, C and Verweij, N and Viberti, C and Wang, L and Warren, Helen and Wootton, R.E and Yanek, Lisa and Yao, Jie and Yousri, N.A and Zhao, W and Adeyemo, A.A and Afaq, S and Aguilar-Salinas, C.A and Akiyama, M and Albert, M.L and Allison, M.A and Alver, Maris and Aung, Tin and Azizi, Joshan and Bentley, Amy and Boeing, Heiner and Boerwinkle, Eric and Borja, J.B and Borst, Gert and Bottinger, Erwin and Broer, L and Campbell, H and Chanock, Stephen and Chee, M.-L and Chen, G and ... and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden and et al
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1
textabstractIn many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the... 
Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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5. Full Text Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
by Joshi, P.K and Pirastu, N and Kentistou, K.A and Fischer, K and Hofer, E and Schraut, K.E and Clark, D.W and Nutile, T and Barnes, C.L.K and Timmers, P and Shen, X and Gandin, I and McDaid, A.F and Hansen, T.F and Gordon, S.D.S and Giulianini, F and Boutin, T.S and Abdellaoui, A and Zhao, W and Medina-Gomez, C and Bartz, T.M and Trompet, S and Lange, L.A and Raffield, L and Spek, A van der and Galesloot, T.E and Proitsi, P and Yanek, L.R and Bielak, L.F and Payton, A and Murgia, F and Concas, M.P and Biino, G and Tajuddin, S.M and Seppala, I and Amin, N and Boerwinkle, E and Borglum, A.D and Campbell, A and Demerath, E.W and Demuth, I and Faul, J.D and Ford, I and Gialluisi, A and Gogele, M and Graff, M and Hingorani, A and Hottenga, J.J and Hougaard, D.M and Hurme, M.A and Ikram, M.A and Jylha, M and Kuh, D and Ligthart, L and Lill, C.M and Lindenberger, U and Lumley, T and Magi, R and Marques-Vidal, P and Medland, S.E and Milani, L and Nagy, R and Ollier, W.E and Peyser, P.A and Pramstaller, P.P and Ridker, P.M and Rivadeneira, F and Ruggiero, D and Saba, Y and Schmidt, R and Schmidt, H and Slagboom, P.E and Smith, B.H and Smith, J.A and Sotoodehnia, N and Steinhagen-Thiessen, E and Rooij, F.J. van and Verbeek, A.L and Vermeulen, S.H and Vollenweider, P and Wang, Y and Werge, T and Whitfield, J.B and Zonderman, A.B and Lehtimaki, T and Evans, M.K and Pirastu, M and Fuchsberger, C and Bertram, L and Pendleton, N and Kardia, S.L and Ciullo, M and Becker, D.M and Wong, A and Psaty, B.M and Duijn, C.M. van and Wilson, J.G and Jukema, J.W and Kiemeney, L.A and Uitterlinden, A.G
Nature Communications, ISSN 2041-1723, 2017, Volume 8
Genomic analysis of longevity offers the potential to illuminate the biology of human aging. Here, using genome-wide association meta-analysis of 606,059... 
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6. Full Text Determination of Octanol-Water Equivalent Partition Coefficients of Indolizine and Substituted 2-Phenylindolizines by Reversed-Phase High-Pressure Liquid Chromatography and Fragmentation Values
by Lins, Claudio L.K and Block, John H and Doerge, Robert F and Barnes, Gerard J
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 06/1982, Volume 71, Issue 6, pp. 614 - 617
Octanol-water partition values were calculated using fragmentation values and measured rapidly by high-pressure liquid chromatography (HPLC) on bonded... 
Indolizine—substituted 2-phenylindolizines, partition coefficients determined by high-pressure liquid chromatography and fragmentation values | High-pressure liquid chromatography—determination of partition coefficients of indolizine and 2-phenylindolizines | Partition coefficient—indolizine and 2-phenylindolizines, determination by high-pressure liquid chromatography and fragmentation values | Fragmentation values—determination of partition coefficients of indolizine and 2-phenylindolizine | Partition coefficient—indolizine and 2‐phenylindolizines, determination by high‐pressure liquid chromatography and fragmentation values | Fragmentation values—determination of partition coefficients of indolizine and 2‐phenylindolizine | High‐pressure liquid chromatography—determination of partition coefficients of indolizine and 2‐phenylindolizines | Indolizine—substituted 2‐phenylindolizines, partition coefficients determined by high‐pressure liquid chromatography and fragmentation values | Indolizines - analysis | Chromatography, High Pressure Liquid - methods | Gas Chromatography-Mass Spectrometry | Solubility
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7. Full Text Archean komatiite volcanism controlled by the evolution of early continents
by David R. Mole and Marco L. Fiorentini and Nicolas Thebaud and Kevin F. Cassidy and T. Campbell McCuaig and Christopher L. Kirkland and Sandra S. Romano and Michael P. Doublier and Elena A. Belousova and Stephen J. Barnes and John Miller
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 28, pp. 10083 - 10088
The generation and evolution of Earth's continental crust has played a fundamental role in the development of the planet. Its formation modified the... 
Earth | Magmatism | Maps | Architecture | Cratons | Geochemistry | Continents | Mantle | Isotopes | Plumes | Ni-Cu-PGE deposits | Crustal evolution | Lithosphere | Mantle plumes | mantle plumes | MULTIDISCIPLINARY SCIENCES | WESTERN | lithosphere | CENTRAL YILGARN CRATON | MANTLE | VOLCANOLOGY | GREENSTONE-BELT | PETROLOGY | CONSTRAINTS | crustal evolution | PLUME | GEOCHEMISTRY | architecture | Archaea - physiology | Biological Evolution | Volcanic Eruptions | Fossils | Research | Geological research | Komatiite | Volcanism | Natural history | Physical Sciences
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8. Full Text Conserved and Variant Epitopes of Plasmodium vivax Duffy Binding Protein as Targets of Inhibitory Monoclonal Antibodies
by Francis B. Ntumngia and Jesse Schloegel and Samantha J. Barnes and Amy M. McHenry and Sanjay Singh and Christopher L. King and John H. Adams
Infection and Immunity, ISSN 0019-9567, 03/2012, Volume 80, Issue 3, pp. 1203 - 1208
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
INFECTIOUS DISEASES | INVASION | BLOOD-GROUP | ERYTHROCYTE-BINDING | STRUCTURAL BASIS | FALCIPARUM | MALARIA | INFECTION | IMMUNOLOGY | RECEPTOR-BINDING | LIGAND DOMAIN | ANTIGEN | Antibodies, Neutralizing | Epitopes - immunology | Antigens, Protozoan - immunology | Antigenic Variation | Enzyme-Linked Immunosorbent Assay | Humans | Conserved Sequence | Neutralization Tests | Plasmodium vivax - immunology | Receptors, Cell Surface - immunology | Antibodies, Monoclonal - immunology | Protozoan Proteins - immunology | Microbial Immunity and Vaccines
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9. Full Text Determination of the molecular basis for a limited dimorphism, N417K, in the plasmodium vivax duffy-binding protein
by McHenry, Amy M and Barnes, Samantha J and Ntumngia, Francis B and King, Christopher L and Adams, John H
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, p. e20192
Invasion of human red blood cells by Plasmodium merozoites is vital for replication and survival of the parasite and, as such, is an attractive target for... 
APICAL MEMBRANE ANTIGEN-1 | SWISS-MODEL | INVASION | RECOGNITION | FALCIPARUM | MULTIDISCIPLINARY SCIENCES | RESISTANCE | MALARIA | INHIBITORY ANTIBODIES | RESIDUES | LIGAND DOMAIN | Mutagenesis, Site-Directed | Humans | Plasmodium vivax - genetics | Protein Binding | Polymorphism, Genetic - genetics | Antigens, Protozoan - genetics | Protozoan Proteins - genetics | Receptors, Cell Surface - genetics | Viral antibodies | Antibodies | Amino acids | Vaccines | Health aspects | Protein binding | Haplotypes | Residues | Erythrocytes | Homology | Infections | Dimorphism | Parasites | Duffy-binding protein | Immunity | Blood | Amino acid substitution | Proteins | Receptors | Red blood cells | Bioinformatics | Blood groups | Antigens | Immunoglobulins | Automation | Cell survival | Blood cells | Merozoites | Mutagenesis | Acids | Lysine | Site-directed mutagenesis | Asparagine | Ligands | Binding sites | Chemokines
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10. Full Text An engineered vaccine of the Plasmodium vivax Duffy binding protein enhances induction of broadly neutralizing antibodies
by Ntumngia, Francis B and Pires, Camilla V and Barnes, Samantha J and George, Miriam T and Thomson-Luque, Richard and Kano, Flora S and Alves, Jessica R. S and Urusova, Darya and Pereira, Dhelio B and Tolia, Niraj H and King, Christopher L and Carvalho, Luzia H and Adams, John H
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 13779 - 11
Plasmodium vivax invasion into human reticulocytes is a complex process. The Duffy binding protein (DBP) dimerization with its cognate receptor is vital for... 
APICAL MEMBRANE ANTIGEN-1 | BLOOD-GROUP | BRAZILIAN AMAZON | MULTIDISCIPLINARY SCIENCES | NATURAL-SELECTION | ACQUIRED INHIBITORY ANTIBODIES | MONOCLONAL-ANTIBODIES | MALARIA PARASITES | RECEPTOR-BINDING | LIGAND DOMAIN | ERYTHROCYTE INVASION | Immune response | Malaria | Lymphocytes B | Immunogenicity | Reticulocytes | Vaccines | Epitopes | Dimerization
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