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BBA - Biomembranes, ISSN 0005-2736, 2007, Volume 1768, Issue 8, pp. 1976 - 1990
Journal Article
2011, Methods in molecular biology, ISBN 1603272232, Volume 752., x, 249
Book
Journal of the American Chemical Society, ISSN 0002-7863, 07/2009, Volume 131, Issue 25, pp. 8760 - 8761
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 01/2009, Volume 131, Issue 3, pp. 1195 - 1207
Numerous conflicting models have been proposed regarding the nature of the Cu2+ coordination environment of the amyloid beta (A beta) peptide, the causative... 
CU(II) BINDING | RESONANCE | COMPUTER-SIMULATION SOFTWARE | COMPLEXES | A-BETA | BINDING-SITE | METAL-IONS | SPECTRA | CHEMISTRY, MULTIDISCIPLINARY | ZINC | ELECTRON-SPIN ECHO | Peptide Fragments - chemistry | Molecular Structure | Copper - chemistry | Amyloid beta-Peptides - chemistry | Electron Spin Resonance Spectroscopy | Alzheimer Disease | Index Medicus
Journal Article
BRAIN, ISSN 0006-8950, 04/2011, Volume 134, pp. 1089 - 1100
While considerable effort has focused on developing positron emission tomography beta-amyloid imaging radiotracers for the early diagnosis of Alzheimer's... 
SENILE DEMENTIA | THIOFLAVIN-T | NEUROFIBRILLARY TANGLES | PROTEIN | tau | imaging | NEUROSCIENCES | PITTSBURGH COMPOUND-B | OLIGOMERS | CLINICAL NEUROLOGY | POSITRON-EMISSION-TOMOGRAPHY | BETA-AMYLOID PLAQUES | QUANTITATIVE ASSESSMENT | PAIRED HELICAL FILAMENTS | dementia | Alzheimer's disease | PET
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2011, Volume 286, Issue 52, pp. 44557 - 44568
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2008, Volume 59, Issue 1, pp. 43 - 55
As a disease-modifying approach for Alzheimer's disease (AD), clioquinol (CQ) targets β-amyloid (Aß) reactions with synaptic Zn and Cu yet promotes metal... 
CELLBIO | HUMDISEASE | MOLNEURO | PROTEIN | AMYLOID-BETA | IN-VIVO | DISEASE | TAU | PATHOLOGY | MODEL | NEUROSCIENCES | ZINC | OLIGOMERS | SYNAPTOPHYSIN
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2008, Volume 28, Issue 46, pp. 11950 - 11958
Alzheimer's disease is an age-related neurodegenerative disorder with its toxicity linked to the generation of amyloid-beta peptide (A beta). Within the A beta... 
Aggregation | Neurotoxicity | Small soluble oligomers | GxxxG | Amyloid-β | Alzheimer's disease | Lipid | FIBRIL FORMATION | ALZHEIMERS-DISEASE | MEMBRANE | aggregation | TOXICITY | lipid | NEUROSCIENCES | OLIGOMERS | amyloid-beta | small soluble oligomers | neurotoxicity | PLAQUE CORE | IN-VIVO | SEQUENCE | PROTEIN FIBRILLOGENESIS | BINDING | amyloid-β
Journal Article
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 11/2016, Volume 16, Issue 27, pp. 3058 - 3068
Pathological aggregation of endogenous proteins is a common feature of many neurodegenerative diseases. This is generally accompanied by elevated levels of... 
atsm | Bis(thiosemicarbazone) | Cu | AD | gtsm | ALS | BTSC | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | bis(thiosemicarbazone) | DITYROSINE CROSS-LINKING | AMYOTROPHIC-LATERAL-SCLEROSIS | MOTOR-NEURON DISEASE | FRONTOTEMPORAL LOBAR DEGENERATION | Cu-II(atsm) | ALZHEIMER A-BETA | POSITRON-EMISSION-TOMOGRAPHY | AMYLOID-BETA | CUII(gtsm) | SUPEROXIDE-DISMUTASE | PARKINSONS-DISEASE
Journal Article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, ISSN 1433-7851, 09/2015, Volume 54, Issue 36, pp. 10460 - 10464
Accumulation of the -amyloid (A) peptide in extracellular senile plaques rich in copper and zinc is a defining pathological feature of Alzheimers disease (AD).... 
SITE | SERUM-ALBUMIN | bioinorganic chemistry | COMPLEXES | peptides | HUMAN PROTAMINE HP2 | NICKEL(II) | CHEMISTRY, MULTIDISCIPLINARY | TERMINAL SEQUENCE | AMYLOID-BETA PEPTIDE | amyloid | A-BETA | copper | PROTEINS | Alzheimer's disease | ALZHEIMERS | Proteins | Homeostasis | Analysis | Binding | Brain | Neurodegenerative diseases | Peptides | Metals | Central nervous system | Zinc | Senile plaques | β-Amyloid | Copper | Alzheimers disease
Journal Article
Journal Article