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1. Full Text B-107 Antibody-Based Vaccines and Therapeutics for HIV-1
by Dan Barouch
Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 11/2014, Volume 67, pp. 1 - 1
  Previous work has shown that Ad26/MVA vectors expressing Env/Gag/Pol can afford partial protection against repetitive SIVmac251 and SHIV-SF162P3 challenges... 
Antiretroviral drugs | Vaccines | Monkeys & apes | Human immunodeficiency virus--HIV
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2. Full Text 115 Immune Correlates of Protection in Rhesus Monkeys
by Dan Barouch
Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2014, Volume 65, pp. 1 - 1
  We have previously reported the protective efficacy of Ad26/MVA vector regimens expressing SIVsmE543 Env/Gag/Pol antigens against SIVmac251 challenge. Here... 
Proteins | Antigens | Vaccines | Correlation analysis | Monkeys & apes
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3. Full Text B-107 Antibody-Based Vaccines and Therapeutics for HIV-1
by Barouch, Dan
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 11/2014, Volume 67, p. 46
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4. Full Text 115 Immune Correlates of Protection in Rhesus Monkeys
by Barouch, Dan
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2014, Volume 65, Issue Suppl 2, pp. 46 - 46
We have previously reported the protective efficacy of Ad26/MVA vector regimens expressing SIVsmE543 Env/Gag/Pol antigens against SIVmac251 challenge. Here we... 
Abstract
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5. Full Text Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques
by McCracken, Michael K and Gromowski, Gregory D and Friberg, Heather L and Lin, Xiaoxu and Abbink, Peter and De La Barrera, Rafael and Eckles, Kenneth H and Garver, Lindsey S and Boyd, Michael and Jetton, David and Barouch, Dan H and Wise, Matthew C and Lewis, Bridget S and Currier, Jeffrey R and Modjarrad, Kayvon and Milazzo, Mark and Liu, Michelle and Mullins, Anna B and Putnak, J. Robert and Michael, Nelson L and Jarman, Richard G and Thomas, Stephen J
PLoS Pathogens, ISSN 1553-7366, 08/2017, Volume 13, Issue 8, pp. e1006487 - e1006487
Studies have demonstrated cross-reactivity of anti-dengue virus (DENV) antibodies in human sera against Zika virus (ZIKV), promoting increased ZIKV infection... 
ORIGINAL ANTIGENIC SIN | PROTECTION | DENGUE HEMORRHAGIC-FEVER | DISEASE SEVERITY | VACCINE | ANTIBODY | MICROBIOLOGY | PATHOGENESIS | T-CELL RESPONSES | VIROLOGY | ENHANCEMENT | CROSS-REACTIVITY | PARASITOLOGY | Viral antibodies | Prevention | Antigen-antibody reactions | Antibodies | Research | Health aspects | Risk factors | Yellow fever | Vector-borne diseases | Cell culture | Epidemics | Cross-reactivity | Dengue fever | Dengue | Viral diseases | Viruses | Zika virus | Infections | Vaccines | Immunity | Fever | Animals | Reaction kinetics | Kinetics | In vitro methods and tests | Neutralization | Index Medicus
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6. Full Text Control of Viremia and Prevention of Clinical AIDS in Rhesus Monkeys by Cytokine-Augmented DNA Vaccination
by Dan H. Barouch and Sampa Santra and Jörn E. Schmitz and Marcelo J. Kuroda and Tong-Ming Fu and Wendeline Wagner and Miroslawa Bilska and Abie Craiu and Xin Xiao Zheng and Georgia R. Krivulka and Kristin Beaudry and Michelle A. Lifton and Christine E. Nickerson and Wendy L. Trigona and Kara Punt and Dan C. Freed and Liming Guan and Sheri Dubey and Danilo Casimiro and Adam Simon and Mary-Ellen Davies and Michael Chastain and Terry B. Strom and Rebecca S. Gelman and David C. Montefiori and Mark G. Lewis and Emilio A. Emini and John W. Shiver and Norman L. Letvin
Science, ISSN 0036-8075, 10/2000, Volume 290, Issue 5491, pp. 486 - 492
With accumulating evidence indicating the importance of cytotoxic T lymphocytes (CTLs) in containing human immunodeficiency virus-1 (HIV-1) replication in... 
T lymphocytes | Plasmids | Viremia | DNA | Vaccination | Viruses | DNA vaccines | Research Articles | Epitopes | Viral load | HIV 1 | HIV-1 | PROTEIN | CELL RESPONSES | PROTECTION | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | INFECTION | MACAQUES | HUMAN-IMMUNODEFICIENCY-VIRUS | CYTOTOXIC T-LYMPHOCYTES | DISEASE PROGRESSION | HIV Antibodies - blood | Humans | Recombinant Fusion Proteins - therapeutic use | Interleukin-2 - therapeutic use | Neutralization Tests | AIDS Vaccines - therapeutic use | Macaca mulatta | Antibodies, Viral - blood | Viral Load | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Simian Immunodeficiency Virus - genetics | HIV-1 - physiology | Interleukin-2 - immunology | HIV Antibodies - immunology | Simian Acquired Immunodeficiency Syndrome - therapy | Simian Immunodeficiency Virus - immunology | T-Lymphocytes, Cytotoxic - immunology | Lymphocyte Activation | HIV Infections - virology | Acquired Immunodeficiency Syndrome - prevention & control | CD4 Lymphocyte Count | Vaccines, DNA - therapeutic use | HIV-1 - genetics | Disease Progression | Simian Immunodeficiency Virus - physiology | Simian Acquired Immunodeficiency Syndrome - prevention & control | Interleukin-2 - genetics | HIV-1 - immunology | Animals | Simian Acquired Immunodeficiency Syndrome - immunology | Virus Replication | HIV Infections - therapy | Antibodies, Viral - immunology | AIDS vaccines | Research | Medical research | HIV | Deoxyribonucleic acid | Human immunodeficiency virus | Vaccines | Monkeys & apes | Human immunodeficiency virus 1 | CD4 antigen | Index Medicus
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7. Full Text The Quest for an HIV-1 Vaccine — Moving Forward
by Barouch, Dan H
The New England Journal of Medicine, ISSN 0028-4793, 11/2013, Volume 369, Issue 22, pp. 2073 - 2076
The challenges in the development of a prophylactic HIV-1 vaccine are unprecedented in the history of vaccinology. But there are reasons for optimism, and... 
DOUBLE-BLIND | THAILAND | MEDICINE, GENERAL & INTERNAL | INFECTION | EFFICACY TRIAL | HIV Infections - prevention & control | HIV-1 - ultrastructure | Adenoviridae | Humans | AIDS Vaccines - immunology | Clinical Trials as Topic | Genetic Vectors | env Gene Products, Human Immunodeficiency Virus | Proteins | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Clinical trials | Infections | Genetic diversity | Vaccines | Transgender persons | Immune system | Index Medicus | Abridged Index Medicus
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8. Full Text HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120
by James M. Kovacs and Joseph P. Nkolola and Hanqin Peng and Ann Cheung and James Perry and Caroline A. Miller and Michael S. Seaman and Dan H. Barouch and Bing Chen
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2012, Volume 109, Issue 30, pp. 12111 - 12116
HIV-1 envelope glycoprotein is the primary target for HIV-1-specific antibodies. The native HIV-1 envelope spike on the virion surface is a trimer, but... 
Antigens | Neutralizing antibodies | Vaccination | Antibodies | Viruses | Trimers | Glycoproteins | Epitopes | Monomers | HIV 1 | IMMUNOGENICITY | EPITOPE | MULTIDISCIPLINARY SCIENCES | VACCINE | IMMUNODEFICIENCY-VIRUS TYPE-1 | HUMAN MONOCLONAL-ANTIBODY | GP140 | BROAD | GLYCOPROTEIN | PROTECTIVE EFFICACY | GP41 ECTODOMAIN | Surface Plasmon Resonance | Guinea Pigs | env Gene Products, Human Immunodeficiency Virus - immunology | Enzyme-Linked Immunosorbent Assay | Humans | Protein Multimerization - immunology | Neutralization Tests | Ultracentrifugation | HIV Envelope Protein gp120 - immunology | Antibodies, Neutralizing - immunology | HIV-1 - immunology | Animals | HIV Antibodies - immunology | Chromatography, Gel | Viral antibodies | Physiological aspects | Development and progression | HIV (Viruses) | Health aspects | Immunology | Vaccines | Human immunodeficiency virus--HIV | Index Medicus | Biological Sciences
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9. Full Text HIV-1 Latency by Transition
by Julg, Boris and Barouch, Dan H
Immunity, ISSN 1074-7613, 10/2017, Volume 47, Issue 4, pp. 611 - 612
The latent HIV-1 reservoir represents the major barrier for the development of an HIV-1 cure. In this issue of , highlight that effector-to-memory... 
CD4(+) T-CELLS | INFECTION | RESERVOIR | IMMUNOLOGY | RHESUS-MONKEYS | HIV Infections | HIV-1 | CD4-Positive T-Lymphocytes | Virus Latency | Humans | HIV (Viruses) | T cells | Prevention | Cytomegalovirus | Memory cells | Immunological memory | Lymphocytes | Human immunodeficiency virus--HIV | Viruses | Infections | Lymphocytes T | Gene expression | Latency | CD4 antigen | Index Medicus
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10. Full Text An immunogenic personal neoantigen vaccine for patients with melanoma
by Ott, Patrick A and Hu, Zhuting and Keskin, Derin B and Shukla, Sachet A and Sun, Jing and Bozym, David J and Zhang, Wandi and Luoma, Adrienne and Giobbie-Hurder, Anita and Peter, Lauren and Chen, Christina and Olive, Oriol and Carter, Todd A and Li, Shuqiang and Lieb, David J and Eisenhaure, Thomas and Gjini, Evisa and Stevens, Jonathan and Lane, William J and Javeri, Indu and Nellaiappan, Kaliappanadar and Salazar, Andres M and Daley, Heather and Seaman, Michael and Buchbinder, Elizabeth I and Yoon, Charles H and Harden, Maegan and Lennon, Niall and Gabriel, Stacey and Rodig, Scott J and Barouch, Dan H and Aster, Jon C and Getz, Gad and Wucherpfennig, Kai and Neuberg, Donna and Ritz, Jerome and Lander, Eric S and Fritsch, Edward F and Hacohen, Nir and Wu, Catherine J
Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7662, pp. 217 - 221
Effective anti-tumour immunity in humans has been associated with the presence of T cells directed at cancer neoantigens(1), a class of HLA-bound peptides that... 
IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | CD4(+) T-CELLS | ANTIGENS | CANCER-IMMUNOTHERAPY | SEQUENCING DATA | EXPRESSION | PEPTIDE | PREDICTION | MOLECULES | EPITOPES | Amino Acid Sequence | Antigens, Neoplasm - genetics | Antibodies, Monoclonal, Humanized - therapeutic use | Neoplasm Recurrence, Local - prevention & control | Antigens, Neoplasm - immunology | Humans | Cancer Vaccines - adverse effects | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Cancer Vaccines - chemistry | Antigens, Neoplasm - chemistry | Machine Learning | CD4-Positive T-Lymphocytes - immunology | Neoplasm Recurrence, Local - immunology | Cancer Vaccines - immunology | Histocompatibility Antigens Class II - immunology | Melanoma - genetics | Melanoma - immunology | Antibodies, Monoclonal, Humanized - pharmacology | Patient Safety | High-Throughput Nucleotide Sequencing | Mutation | CD8-Positive T-Lymphocytes - immunology | Melanoma - therapy | Precision Medicine - methods | Care and treatment | Methods | Melanoma | Cancer | Peptides | PD-1 protein | CD8 antigen | Vaccination | Feasibility analysis | Lymphocytes T | Vaccines | Tissues | Immunity | Thymus | Lymphocytes | Immunotherapy | Antigens | Feasibility studies | T cell receptors | Gene expression | Patients | Immunological tolerance | CD4 antigen | Studies | Immune checkpoint | Immunogenicity | Cell death | Histocompatibility antigen HLA | Tumors | Apoptosis | Index Medicus
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11. Full Text Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination
by Mahan, Alison E and Jennewein, Madeleine F and Suscovich, Todd and Dionne, Kendall and Tedesco, Jacquelynne and Chung, Amy W and Streeck, Henik and Pau, Maria and Schuitemaker, Hanneke and Francis, Don and Fast, Patricia and Laufer, Dagna and Walker, Bruce D and Baden, Lindsey and Barouch, Dan H and Alter, Galit
PLoS pathogens, ISSN 1553-7366, 2016, Volume 12, Issue 3, pp. e1005456 - e1005456
Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role... 
HIV Seropositivity | Humans | Immunoglobulin G | Vaccination | Antibody-Dependent Cell Cytotoxicity - immunology | Male | Glycosylation | HIV Antibodies - isolation & purification | HIV Infections - immunology | Immunoglobulin Fc Fragments - immunology | HIV Antibodies - immunology | HIV Antigens - immunology | Female | Phagocytosis | Cohort Studies | RHEUMATOID-ARTHRITIS | THERAPEUTICS | COMPLEMENT | HIV-INFECTION | INHIBITION | FC-GAMMA-RIII | MECHANISM | MULTIDISCIPLINARY SCIENCES | N-GLYCANS | HUMAN-IGG | INFLUENZA | Infection | Antigens | AIDS vaccines | Health aspects | HIV infection | Research | Pathogens | Flow cytometry | Immunoglobulins | Bacterial infections | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Colleges & universities | Cytotoxicity | Infections | Vaccines | Immune system | Index Medicus | AIDS | Acquired immune deficiency syndrome | HIV | Human immunodeficiency virus
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12. Full Text Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection
by Wagh, Kshitij and Bhattacharya, Tanmoy and Williamson, Carolyn and Robles, Alex and Bayne, Madeleine and Garrity, Jetta and Rist, Michael and Rademeyer, Cecilia and Yoon, Hyejin and Lapedes, Alan and Gao, Hongmei and Greene, Kelli and Louder, Mark K and Kong, Rui and Karim, Salim Abdool and Burton, Dennis R and Barouch, Dan H and Nussenzweig, Michel C and Mascola, John R and Morris, Lynn and Montefiori, David C and Korber, Bette and Seaman, Michael S
PLoS Pathogens, ISSN 1553-7366, 03/2016, Volume 12, Issue 3, pp. e1005520 - e1005520
The identification of a new generation of potent broadly neutralizing HIV-1 antibodies (bnAbs) has generated substantial interest in their potential use for... 
Epitopes - immunology | HIV Infections - immunology | HIV Infections - prevention & control | Antibodies, Neutralizing - immunology | HIV-1 - immunology | HIV Antibodies - immunology | Humans | Infection | Prevention | Viral antibodies | Usage | Analysis | Antibodies | B cells | HIV (Viruses) | Health aspects | Antigenic determinants | Care and treatment | Neutralization (Chemistry) | Research | Studies | Immunization | Immunoglobulins | Acquired immune deficiency syndrome--AIDS | Infections | Mathematical models | Viral infections | Binding sites | Index Medicus | Acquired immune deficiency syndrome | AIDS
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13. Full Text Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys
by Abbink, Peter and Larocca, Rafael A and De La Barrera, Rafael A and Bricault, Christine A and Moseley, Edward T and Boyd, Michael and Kirilova, Marinela and Li, Zhenfeng and Ng'ang'a, David and Nanayakkara, Ovini and Nityanandam, Ramya and Mercado, Noe B and Borducchi, Erica N and Agarwal, Arshi and Brinkman, Amanda L and Cabral, Crystal and Chandrashekar, Abishek and Giglio, Patricia B and Jetton, David and Jimenez, Jessica and Lee, Benjamin C and Mojta, Shanell and Molloy, Katherine and Shetty, Mayuri and Neubauer, George H and Stephenson, Kathryn E and Peron, Jean Pierre S and De Zanotto, Paolo M.A and Misamore, Johnathan and Finneyfrock, Brad and Lewis, Mark G and Alter, Galit and Modjarrad, Kayvon and Jarman, Richard G and Eckels, Kenneth H and Michael, Nelson L and Thomas, Stephen J and Barouch, Dan H
Science, ISSN 0036-8075, 09/2016, Volume 353, Issue 6304, pp. 1129 - 1132
Zika virus (ZIKV) is responsible for a major ongoing epidemic in the Americas and has been causally associated with fetal microcephaly. The development of a... 
ANTIBODIES | INFECTION | MICE | MULTIDISCIPLINARY SCIENCES | Immunogenicity, Vaccine | Puerto Rico | Adenoviridae | Immunoglobulins - immunology | Humans | Vaccines, DNA - immunology | Male | Macaca mulatta | Adoptive Transfer | Vaccines, DNA - administration & dosage | Immunoglobulins - isolation & purification | Brazil | Female | Zika Virus Infection - prevention & control | Antibodies, Viral - biosynthesis | Zika Virus - immunology | Viral Envelope Proteins - genetics | Viral Vaccines - administration & dosage | Vaccines, Inactivated - immunology | Animals | Vaccines, Inactivated - administration & dosage | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Mice | Mice, Inbred BALB C | Genetic Vectors | Viral Vaccines - immunology | Vaccination | Vaccines | Rhesus monkey | Dosage and administration | Viral vaccines | Health aspects | Medical research | Zika virus | Monkeys & apes | Index Medicus | Platforms | Effectiveness | Neutralizing | Antibodies | Viruses | Monkeys | Recombinant
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14. Full Text Vaccine protection against Zika virus from Brazil
by Larocca, Rafael A and Abbink, Peter and Peron, Jean Pierre S and Zanotto, Paolo M. De A and Iampietro, M. Justin and Badamchi-Zadeh, Alexander and Boyd, Michael and Ng'ang'a, David and Kirilova, Marinela and Nityanandam, Ramya and Mercado, Noe B and Li, Zhenfeng and Moseley, Edward T and Bricault, Christine A and Borducchi, Erica N and Giglio, Patricia B and Jetton, David and Neubauer, George and Nkolola, Joseph P and Maxfield, Lori F and De La Barrera, Rafael A and Jarman, Richard G and Eckels, Kenneth H and Michael, Nelson L and Thomas, Stephen J and Barouch, Dan H
Nature, ISSN 0028-0836, 06/2016, Volume 536, Issue 7617, pp. 474 - 478
Zika virus (ZIKV) is a flavivirus that is responsible for the current epidemic in Brazil and the Americas(1,2). ZIKV has been causally associated with fetal... 
CHALLENGE | HEALTHY-ADULTS | IMMUNOGENICITY | AMERICA | NEUTRALIZING ANTIBODY | SAFETY | MULTIDISCIPLINARY SCIENCES | INFECTION | MICE | MODEL | Antibody Specificity | Immunoglobulin G - isolation & purification | Vaccines, DNA - genetics | Zika Virus - genetics | Vaccines, Subunit - genetics | Humans | Viral Vaccines - genetics | Vaccines, DNA - immunology | Adoptive Transfer | Microcephaly - virology | CD4-Positive T-Lymphocytes - immunology | Zika Virus Infection - virology | Antibodies, Neutralizing - immunology | Immunoglobulin G - immunology | Gene Deletion | Brazil | Zika Virus Infection - complications | Female | Zika Virus Infection - prevention & control | Zika Virus - immunology | Microcephaly - complications | Vaccines, Inactivated - genetics | Viral Envelope Proteins - genetics | Vaccines, Subunit - chemistry | Vaccines, Subunit - immunology | Zika Virus - chemistry | Vaccines, DNA - chemistry | Vaccines, Inactivated - immunology | Animals | Viral Envelope Proteins - chemistry | Viral Vaccines - chemistry | Zika Virus Infection - immunology | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Viral Vaccines - immunology | Vaccines, Inactivated - chemistry | Product development | Viral vaccines | Studies | Epidemics | Encephalitis | Immunization | Fetuses | Zika virus | Vaccines | Microcephaly | Deoxyribonucleic acid--DNA | Index Medicus
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