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by Borghini, L and Png, E and Binder, A and Wright, VJ and Pinnock, E and de Groot, R and Hazelzet, J and Emonts, M and Van der Flier, M and Schlapbach, LJ and Anderson, S and Secka, F and Salas, A and Fink, C and Carrol, ED and Pollard, AJ and Coin, LJ and Kuijpers, TW and Martinon-Torres, F and Zenz, W and Levin, M and Hibberd, ML and Davila, S and Gormley, S and Hamilton, S and Herberg, J and Hourmat, B and Hoggart, C and Kaforou, M and Sancho-Shimizu, V and Abdulla, A and Agapow, P and Bartlett, M and Bellos, E and Eleftherohorinou, H and Galassini, R and Inwald, D and Mashbat, M and Menikou, S and Mustafa, S and Nadel, S and Rahman, R and Thakker, C and Bokhandi, S and Power, S and Barham, H and Pathan, N and Ridout, J and White, D and Thurston, S and Faust, S and Patel, S and McCorkell, J and Davies, P and Cratev, L and Navarra, H and Carter, S and Ramaiah, R and Patel, R and Tuffrey, C and Gribbin, A and McCready, S and Peters, M and Hardy, K and Standing, F and O'Neill, L and Abelake, E and Deep, A and Nsirim, E and Willis, L and Young, Z and Royad, C and White, S and Fortune, PM and Hudnott, P and Gonzalez, FA and Barral-Arca, R and Cebey-Lopez, M and Curras-Tuala, MJ and Garcia, N and Vicente, LG and Gomez-Carballa, A and Rial, JG and Beiroa, AG and Grande, AJ and Iglesias, PL and Santos, AEM and Martinon-Torres, N and Sanchez, JMM and Perez, BM and Pacheco, PO and Pardo-Seco, J and Pischedda, S and Calle, IR and Rodriguez-Tenreiro, C and Redondo-Collazo, L and Fernandez, SS and Silva, MDP and Vega, A and Reyes, SB and ... and EUCLIDS Consortium and EUCLIDS consortium
SCIENTIFIC REPORTS, ISSN 2045-2322, 05/2019, Volume 9, Issue 1, pp. 6966 - 15
Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we... 
KAPPA-B | SEQUENCE VARIATION | BINDING | MULTIDISCIPLINARY SCIENCES | GENOME | NF-κB protein | Phenotypes | Disease | Epithelial cells | Association analysis | Single-nucleotide polymorphism | Regulatory sequences | Vaccines | Genetic variance | Infectious diseases | Genotyping | RelA protein | Binding sites | Meningococcal disease
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8043 - 7
Recently, a biomarker signature consisting of 2-transcript host RNAs was proposed for discriminating bacterial from viral infections in febrile children. We... 
Pathogens | Transcription | Biomarkers | Diarrhea | Bacteria | Children | Ribonucleic acid--RNA | Minority & ethnic groups | Viral infections
Journal Article
Journal Article
RNA, ISSN 1355-8382, 07/2019, Volume 25, Issue 7, pp. 857 - 868
There is a growing body of evidence suggesting that patterns of gene expression vary within and between human populations. However, the impact of this... 
RNA-seq | VARIANTS | biogeographical ancestry | BIOCHEMISTRY & MOLECULAR BIOLOGY | transcriptomics | SNPs | GENE-EXPRESSION | genomics | SAMPLES | ASSOCIATION | SIGNATURE | gene expression | Datasets | Genomes | Ribonucleic acid--RNA | Gene expression
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 12630 - 15
The territory of present-day Vietnam was the cradle of one of the world's earliest civilizations, and one of the first world regions to develop agriculture. We... 
MIGRATION | POPULATION-GENETICS | MAXIMUM-LIKELIHOOD | SOUTHEAST-ASIA | MULTIDISCIPLINARY SCIENCES | EAST-ASIA | TREE | DIVERSITY | POLYMORPHISM | DIFFERENTIATION | MITOCHONDRIAL-DNA | Haplotypes | Gene flow | Territory | Population growth | Genomes | Single-nucleotide polymorphism | Mitochondrial DNA | Rivers | Bayesian analysis | Minority & ethnic groups | Index Medicus
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 1 - 12
The diagnosis of bacterial infections in hospital settings is currently performed using bacterial culture from sterile site, but they are lengthy and limited.... 
DIAGNOSIS | STREPTOCOCCUS-PNEUMONIAE | TECHNOLOGIES | HOST RNA SIGNATURE | MULTIDISCIPLINARY SCIENCES | VALIDATION | TIME RT-PCR | NORMALIZATION | HOUSEKEEPING GENES | CANCER | Bacterial infections | DNA microarrays | Transcription | Bacteria | Infections | Children | Diagnosis | Gene expression | Index Medicus
Journal Article
Conference Proceeding
Journal Article
by Martinón-Torres, Federico and Salas, Antonio and Rivero-Calle, Irene and Cebey-López, Miriam and Pardo-Seco, Jacobo and Herberg, Jethro A and Boeddha, Navin P and Klobassa, Daniela S and Secka, Fatou and Paulus, Stephane and de Groot, Ronald and Schlapbach, Luregn J and Driessen, Gertjan J and Anderson, Suzanne T and Emonts, Marieke and Zenz, Werner and Carrol, Enitan D and Van der Flier, Michiel and Levin, Michael and Levin, Michael and Coin, Lachlan and Gormley, Stuart and Hamilton, Shea and Herberg, Jethro and Hourmat, Bernardo and Hoggart, Clive and Kaforou, Myrsini and Sancho-Shimizu, Vanessa and Wright, Victoria and Abdulla, Amina and Agapow, Paul and Bartlett, Maeve and Bellos, Evangelos and Eleftherohorinou, Hariklia and Galassini, Rachel and Inwald, David and Mashbat, Meg and Menikou, Stefanie and Mustafa, Sobia and Nadel, Simon and Rahman, Rahmeen and Thakker, Clare and Bokhandi, Sumit and Power, Sue and Barham, Heather and Pathan, Nazima and Ridout, Jenna and White, Deborah and Thurston, Sarah and Faust, Saul and Patel, Sanjay and McCorkell, Jenni and Davies, Patrick and Crate, Lindsey and Navarra, Helen and Carter, Stephanie and Ramaiah, Raghu and Patel, Rekha and Tuffrey, Catherine and Gribbin, Andrew and McCready, Sharon and Peters, Mark and Hardy, Katie and Standing, Fran and O'Neill, Lauren and Abelake, Eugenia and Deep, Akash and Nsirim, Eniola and Pollard, Andrew and Willis, Louise and Young, Zoe and Royad, C and White, Sonia and Fortune, Peter Marc and Hudnott, Phil and Martinón-Torres, Federico and Salas Ellacuriaga, Antonio and Álvez González, Fernando and Barral-Arca, Ruth and Cebey-López, Miriam and Curras-Tuala, María José and García, Natalia and García Vicente, Luisa and Gómez-Carballa, Alberto and Gómez Rial, Jose and Grela Beiroa, Andrea and Justicia Grande, Antonio and Leboráns Iglesias, Pilar and Martínez Santos, Alba Elena and Martinón-Torres, Nazareth and Martinón Sánchez, José María and Morillo Gutiérrez, Beatriz and Mosquera Pérez, Belén and Obando Pacheco, Pablo and Pardo-Seco, Jacobo and Pischedda, Sara and Rivero-Calle, Irene and Rodríguez-Tenreiro, Carmen and Redondo-Collazo, Lorenzo and Serén Fernández, Sonia and ... and EUCLIDS Consortium
The Lancet Child and Adolescent Health, 06/2018, Volume 2, Issue 6, pp. 404 - 414
Background: Sepsis and severe focal infections represent a substantial disease burden in children admitted to hospital. We aimed to understand the burden of... 
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 15888 - 13
Journal Article
by Martinón-Torres, Federico and Png, Eileen and Khor, Chiea Chuen and Davila, Sonia and Wright, Victoria J and Sim, Kar Seng and Vega, Ana and Fachal, Laura and Inwald, David and Nadel, Simon and Carrol, Enitan D and Martinón-Torres, Nazareth and Alonso, Sonia Marcos and Carracedo, Angel and Morteruel, Elvira and López-Bayón, Julio and Torre, Andrés Concha and Monge, Cristina Calvo and De Aguilar, Pilar Azcón González and Torné, Elisabeth Esteban and Martínez-Padilla, María Del Carmen and Martinón-Sánchez, José María and Levin, Michael and Hibberd, Martin L and Salas, Antonio and Gómez-Carballa, Alberto and Cebey, Miriam and Sánchez, Natalia García and Calle, Irene Rivero and Grande, Antonio Justicia and Pardo-Seco, Jacobo and Barral-Arca, Ruth and Pischedda, Sara and Currás-Tuala, María-José and Rodriguez-Tenreiro, Carmen and Redondo-Collazo, Lorenzo and Sánchez, Fernanda Pardo and De La Cruz Moreno, Jesús and Millán Miralles, Ma. Leticia and García Rodríguez, José Luis and García, Susana Rey and Doce, Ana Hurtado and Barba, Ángela Ferrer and Pallares, Manuel Ortiz and Romero, Alfredo Reparaz and Muñoz Bonet, Juan Ignacio and Cancela, Manuel Silveira and Bergara, Eider Oñate and Arriortua, Amaya Bustinza and Navarro Gómez, María Luisa and Fernández, Mario Sánchez and Martínez, Xavier Allué and Ortega, Álvaro Castellanos and Rosso, Servando Pantoja and Caballero Macarrón, César Pérez and Menchón, Natalia Molini and Sánchez, Francisco Giménez and Garzón, Manuel González-Ripoll and García, María Del Mar Ballesteros and Sánchez Granados, José Manuel and Ayestarán, Olga Serrano and Payo, Roman and Palazón, Sonia Cañadas and León León, Maria Cruz and Dominguez, Susana Reyes and Villanueba, David Arjona and Alonso Martín, J. Antonio and Orayen, Concepción Goñi and Iturbe, Enrique Bernaola and Alonso Salas, María Teresa and Fernández, Isabel Quintela and