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Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 14 - 12
Clinical data acquired over the last decade on non-small cell lung cancer (NSCLC) treatment with small molecular weight Epidermal Growth Factor Receptor (EGFR)... 
Acrylamide | Epidermal growth factor | Epidermal growth factor receptors | Melanoma | Non-small cell lung carcinoma | Tumor cell lines | Colon | Pancreas | Prostate | Molecular weight | Tumors
Journal Article
Anais da Academia Brasileira de Ciencias, ISSN 0001-3765, 07/2019, Volume 91, Issue supp 3, p. e20190306
This manuscript describes the role of natural products in the process of drug discovery. In fact, several different natural compounds have been used as... 
natural products as lead-compounds to drugs | natural biophores as drug scaffolds | new drugs candidates | MULTIDISCIPLINARY SCIENCES | medicinal chemistry
Journal Article
Letters in Drug Design & Discovery, ISSN 1570-1808, 11/2017, Volume 14, Issue 11, p. 1227
Journal Article
Revista Virtual de Quimica, 2018, Volume 10, Issue 1, p. 1
Journal Article
Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 2018, Volume 18, Issue 15, pp. 1265 - 1269
Still now, for many forms of the disseminated cancers there is no curative therapy available. The discovery of novel active chemotherapeutic agents is largely... 
Polyphenols | Anticancer agent | Dietary components | Significance | Chemotherapeutic agents | Cancer | ANTIOXIDANT ACTIVITY | polyphenols | PLANT | TEA POLYPHENOLS | SUPEROXIDE | CHEMISTRY, MEDICINAL | HYPOCHLOROUS ACID | dietary components | INFUSION | MECHANISMS | chemotherapeutic agents | significance | SCAVENGING ACTIVITY | ORAL BIOAVAILABILITY | cancer | CANCER CHEMOPREVENTION
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 02/2016, Volume 14, Issue 7, pp. 2291 - 2296
Journal Article
Revista Virtual de Quimica, 08/2017, Volume 9, Issue 4, p. 1393
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2018, Volume 13, Issue 4, p. e0195047
Pulmonary hypertension (PH) is characterized by enhanced pulmonary vascular resistance, which causes right ventricle (RV) pressure overload and results in... 
Complications and side effects | Drug interactions | Physiological aspects | Dosage and administration | Sildenafil | Research | Drug therapy | Pulmonary hypertension
Journal Article
ISSN 1477-0520, 2/2016, Volume 14, Issue 7, pp. 2291 - 2296
A practical and convergent asymmetric route to calcium atorvastatin ( 1 ) is reported. The synthesis of calcium atorvastatin ( 1 ) was performed using the... 
Journal Article
Journal Article
RSC Drug Discovery Series, ISSN 2041-3203, 2016, Volume 2016-, Issue 50, pp. 1 - 15
Journal Article
Pharmaceuticals, ISSN 1424-8247, 12/2018, Volume 11, Issue 4, p. 119
Pulmonary arterial hypertension (PAH) is a chronic cardiovascular disease that displays inflammatory components, which contributes to the difficulty of... 
Crystal structure determination | receptor | PDE4 inhibitor | Chalcogen bond | X-ray powder diffractometry | Sigma-hole | N-acylhydrazone | Adenosine A | sigma-hole | crystal structure determination | adenosine A2A receptor | chalcogen bond
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 10/2017, Volume 8
Silicosis is a lethal fibro-granulomatous pulmonary disease highly prevalent in developing countries, for which no proper therapy is available. Among a small... 
LASSBio-897 | receptor | CAMP | Silicosis | Fibrosis | Silica | silicosis | fibrosis | A2A receptor | cAMP
Journal Article
Current topics in medicinal chemistry, 06/2019
The medicinal chemist has an utmost role in the drug design, discovery and development process. Its primary goal is to discover leads and optimize them to... 
Journal Article
Journal Article
Quimica Nova, ISSN 0100-4042, 2009, Volume 32, Issue 3, pp. 679 - 688
Journal Article
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