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Nature, ISSN 0028-0836, 05/2012, Volume 485, Issue 7399, pp. 507 - 511
The mechanisms leading to neuronal death in neurodegenerative disease are poorly understood. Many of these disorders, including Alzheimer's, Parkinson's and... 
UNFOLDED PROTEIN RESPONSE | TOXICITY IN-VIVO | ALZHEIMERS-DISEASE | ER STRESS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MICE | ENDOPLASMIC-RETICULUM STRESS | DYSFUNCTION | PRP | PROTEOSTASIS | Neurons - pathology | Neuroprotective Agents | Phosphorylation | Prions - genetics | Eukaryotic Initiation Factor-2 - chemistry | Neurodegenerative Diseases - etiology | PrPSc Proteins - analysis | Synapses - pathology | Thiourea - pharmacology | Phosphoproteins - metabolism | Repressor Proteins - analysis | PrPSc Proteins - metabolism | Synapses - metabolism | Phosphoproteins - analysis | Protein Folding - drug effects | Protein Phosphatase 1 - genetics | Eukaryotic Initiation Factor-2 - metabolism | Synaptic Transmission - drug effects | Cell Death - drug effects | PrPSc Proteins - toxicity | Neurons - drug effects | Repressor Proteins - metabolism | Prions - metabolism | Synapses - drug effects | Repressor Proteins - chemistry | Neurodegenerative Diseases - pathology | Mice, Inbred C57BL | Kaplan-Meier Estimate | Hippocampus - pathology | Prion Diseases - pathology | Neurodegenerative Diseases - metabolism | Hippocampus - cytology | Cinnamates - pharmacology | Eukaryotic Initiation Factor-2 - analysis | Hippocampus - metabolism | Protein Phosphatase 1 - metabolism | Animals | Prions - biosynthesis | Protein Biosynthesis - drug effects | Mice | Unfolded Protein Response - physiology | Thiourea - analogs & derivatives
Journal Article
Brain, ISSN 0006-8950, 2017, Volume 140, Issue 6, pp. 1768 - 1783
Journal Article
ORGANIC LETTERS, ISSN 1523-7060, 03/2019, Volume 21, Issue 5, pp. 1526 - 1529
A method for siladifluoromethylation of dialkyl phosphonates and secondary phosphine oxides with TMSCF3 to produce nucleophilic P-V-CF2- transfer reagents is... 
NUCLEOPHILIC TRIFLUOROMETHYLATION | DIFLUOROMETHYLATION | POTENT | ANALOGS | ALPHA-SILYLDIFLUOROMETHYLPHOSPHONATES | CHEMISTRY, ORGANIC | FLUORINE | ALDEHYDES | ARYL | DIFLUORINATION
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2004, Volume 14, Issue 19, pp. 4897 - 4902
A series of ketoamides were synthesized and evaluated for inhibitory activity against cathepsin K. Exploration of the interactions between achiral P... 
Cathepsin K | Ketoamide | Cysteine protease inhibitor | DESIGN | CHEMISTRY, MEDICINAL | EXPLORATION | CHEMISTRY, ORGANIC | cathepsin K | cysteine protease inhibitor | ketoamide | TOOL
Journal Article
Archives of Disease in Childhood, ISSN 0003-9888, 05/2017, Volume 102, Issue Suppl 1, pp. A116 - A117
AimsThe role of point-of-care (POC) ketones in relation to acute dehydration with ketosis in the paediatric emergency department (PED) has yet to be... 
Journal Article
Computers and Operations Research, ISSN 0305-0548, 2009, Volume 36, Issue 12, pp. 3166 - 3177
Small package delivery companies offer services where packages are guaranteed to be delivered within a given time-frame. With variability in travel time, the... 
Chance-constrained formulation | Hub-and-spoke network | Stochastic programming | GRAPH | NETWORK | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | OPERATIONS RESEARCH & MANAGEMENT SCIENCE | SINGLE | SWITCHING CENTERS | ENGINEERING, INDUSTRIAL | LOCATION-PROBLEMS
Journal Article
Archives of Disease in Childhood, ISSN 0003-9888, 05/2017, Volume 102, Issue Suppl 1, pp. A92 - A93
AimThere is currently no national guidance for which blood tests should be performed at annual review for individuals with coeliac disease. NICE and BSPGHAN... 
Journal Article
by Chatrchyan, S and Khachatryan, V and Sirunyan, AM and Tumasyan, A and Adam, W and Bergauer, T and Dragicevic, M and Ero, J and Fabjan, C and Friedl, M and Fruhwirth, R and Ghete, VM and Hammer, J and Hoch, M and Hormann, N and Hrubec, J and Jeitler, M and Kiesenhofer, W and Krammer, M and Liko, D and Mikulec, I and Pernicka, M and Rahbaran, B and Rohringer, C and Rohringer, H and Schofbeck, R and Strauss, J and Taurok, A and Teischinger, F and Wagner, P and Waltenberger, W and Walzel, G and Widl, E and Wulz, CE and Mossolov, V and Shumeiko, N and Gonzalez, JS and Bansal, S and Benucci, L and Cornelis, T and De Wolf, EA and Janssen, X and Luyckx, S and Maes, T and Mucibello, L and Ochesanu, S and Roland, B and Rougny, R and Selvaggi, M and Van Haevermaet, H and Van Mechelen, P and Van Remortel, N and Van Spilbeeck, A and Blekman, F and Blyweert, S and D'Hondt, J and Suarez, RG and Kalogeropoulos, A and Maes, M and Olbrechts, A and Van Doninck, W and Van Mulders, P and Van Onsem, GP and Villella, I and Charaf, O and Clerbaux, B and De Lentdecker, G and Dero, V and Gay, APR and Hammad, GH and Hreus, T and Leonard, A and Marage, PE and Thomas, L and Velde, CV and Vanlaer, P and Wickens, J and Adler, V and Beernaert, K and Cimmino, A and Costantini, S and Garcia, G and Grunewald, M and Klein, B and Lellouch, J and Marinov, A and Mccartin, J and Rios, AAO and Ryckbosch, D and Strobbe, N and Thyssen, F and Tytgat, M and Vanelderen, L and Verwilligen, P and Walsh, S and Yazgan, E and Zaganidis, N and Basegmez, S and Bruno, G and Ceard, L and ... and Collaboration, C
EUROPEAN PHYSICAL JOURNAL C, ISSN 1434-6044, 03/2012, Volume 72, Issue 3
The transverse momentum spectra of charged particles have been measured in pp and PbPb collisions at root s(NN) = 2.76 TeV by the CMS experiment at the LHC. In... 
LHC | PHYSICS, PARTICLES & FIELDS
Journal Article
by Chatrchyan, S and Khachatryan, V and Sirunyan, A.M and Tumasyan, A and Adam, W and Bergauer, T and Dragicevic, M and Erö, J and Fabjan, C and Friedl, M and Frühwirth, R and Ghete, V.M and Hammer, J and Hoch, M and Hörmann, N and Hrubec, J and Jeitler, M and Kiesenhofer, W and Krammer, M and Liko, D and Mikulec, I and Pernicka, M and Rahbaran, B and Rohringer, C and Rohringer, H and Schöfbeck, R and Strauss, J and Taurok, A and Teischinger, F and Wagner, P and Waltenberger, W and Walzel, G and Widl, E and Wulz, C.-E and Mossolov, V and Shumeiko, N and Suarez Gonzalez, J and Bansal, S and Benucci, L and Cornelis, T and de Wolf, E.A and Janssen, X and Luyckx, S and Maes, T and Mucibello, L and Ochesanu, S and Roland, B and Rougny, R and Selvaggi, M and van Haevermaet, H and van Mechelen, P and van Remortel, N and van Spilbeeck, A and Blekman, F and Blyweert, S and D'Hondt, J and Gonzalez Suarez, R and Kalogeropoulos, A and Maes, M and Olbrechts, A and van Doninck, W and van Mulders, P and van Onsem, G.P and Villella, I and Charaf, O and Clerbaux, B and de Lentdecker, G and Dero, V and Gay, A.P.R and Hammad, G.H and Hreus, T and Léonard, A and Marage, P.E and Thomas, L and Vander Velde, C and Vanlaer, P and Wickens, J and Adler, V and Beernaert, K and Cimmino, A and Costantini, S and Garcia, G and Grunewald, M and Klein, B and Lellouch, J and Marinov, A and Mccartin, J and Ocampo Rios, A.A and Ryckbosch, D and Strobbe, N and Thyssen, F and Tytgat, M and Vanelderen, L and Verwilligen, P and Walsh, S and Yazgan, E and Zaganidis, N and Basegmez, S and Bruno, G and Ceard, L and ...
European Physical Journal C, ISSN 1434-6044, 2012, Volume 72, Issue 3, pp. 1 - 22
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 08/2019, Volume 220, Issue 7, pp. 1188 - 1198
Abstract Recent studies have illustrated the burden Cryptosporidium infection places on the lives of malnourished children and immunocompromised individuals.... 
Cryptosporidium | INFECTIOUS DISEASES | P-gp | DIARRHEA | PROTEIN | drug development | MICROBIOLOGY | DRUG-RESISTANCE | IMMUNOLOGY | BINDING CASSETTE TRANSPORTERS | enteric | CHILDREN | gastrointestinal | drug efflux | PARVUM | BUMPED-KINASE INHIBITORS | ABC TRANSPORTERS | MULTIDRUG-RESISTANCE | EXPRESSION | Index Medicus | Abridged Index Medicus | Major and Brief Reports
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2015, Volume 125, Issue 7, pp. 2646 - 2660
Journal Article