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Molecular Therapy, ISSN 1525-0016, 03/2018, Volume 26, Issue 3, pp. 669 - 671
Journal Article
Medicine & Science in Sports & Exercise, ISSN 0195-9131, 06/2019, Volume 51, Issue 6 Suppl, pp. 885 - 886
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 39, pp. 15112 - 15117
Journal Article
Human Gene Therapy, ISSN 1043-0342, 02/2012, Volume 23, Issue 2, pp. 139 - 140
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2009, Volume 106, Issue 38, pp. 16363 - 16368
Alpha-1 antitrypsin (AAT) deficiency is well-suited as a target for human gene transfer. We performed a phase 1, open-label, doseescalation clinical trial of a... 
T lymphocytes | Genetic vectors | Neutralizing antibodies | Enzyme linked immunosorbent assay | Antibodies | Clinical trials | Capsid | Transgenes | Gene therapy | Blood | CTL | Immune response | AAV | Pulmonary | MULTIDISCIPLINARY SCIENCES | pulmonary | gene therapy | NEUTROPHIL ELASTASE | VIRAL VECTORS | DEFICIENCY | SKELETAL-MUSCLE | PHARMACOKINETICS | immune response | INTRAMUSCULAR INJECTION | IMMUNE-RESPONSES | ADENOASSOCIATED VIRUS VECTORS | ALPHA-1-ANTITRYPSIN GENE | AUGMENTATION THERAPY | CD8-Positive T-Lymphocytes - cytology | Dependovirus - genetics | Genetic Vectors - administration & dosage | Humans | Middle Aged | Male | Capsid - enzymology | Antibodies, Viral - blood | Recombinant Fusion Proteins - metabolism | CD4-Positive T-Lymphocytes - immunology | T-Lymphocytes - metabolism | Time Factors | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | alpha 1-Antitrypsin Deficiency - genetics | Cell Line | Gene Expression | alpha 1-Antitrypsin - genetics | alpha 1-Antitrypsin Deficiency - therapy | Enzyme-Linked Immunosorbent Assay | alpha 1-Antitrypsin - blood | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Dependovirus - immunology | Injections, Intramuscular | Genetic Vectors - genetics | Recombinant Fusion Proteins - blood | Capsid - immunology | T-Lymphocytes - cytology | Recombinant Fusion Proteins - genetics | T-Lymphocytes - immunology | Aged | alpha 1-Antitrypsin - metabolism | CD8-Positive T-Lymphocytes - immunology | Genetic Therapy - methods | Enzymes | Lymphocytes | Genomics | Viruses | Gene expression | Cells | Index Medicus | Biological Sciences
Journal Article
JAMA, ISSN 0098-7484, 11/2011, Volume 306, Issue 19, pp. 2110 - 2119
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2016, Volume 17, Issue 2, pp. 159 - 168
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 9, pp. e106435 - e106435
Journal Article