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Cell Cycle, ISSN 1538-4101, 02/2011, Volume 10, Issue 3, pp. 457 - 468
Cellular senescence, an irreversible proliferation arrest evoked by stresses such as oncogene activation, telomere dysfunction, or diverse genotoxic insults,... 
Proteins | Binding | Landes | Calcium | Biology | Bioscience | Cell | Cycle | Organogenesis | Cancer | Bacterial toxin | DNA damage response | Replication stress | Etoposide | Histone 3 trimethylated on lysine 9 | Hydroxyurea | Activated Ras oncogene | Senescence-associated heterochromatin foci
Journal Article
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2010, Volume 12, Issue 1, pp. 80 - 86
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2006, Volume 8, Issue 8, pp. 870 - 876
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2012, Volume 209, Issue 3, pp. 507 - 520
Journal Article
Cell Cycle, ISSN 1538-4101, 10/2012, Volume 11, Issue 20, pp. 3837 - 3850
Impaired DNA damage response pathways may create vulnerabilities of cancer cells that can be exploited therapeutically. One such selective vulnerability is the... 
predictive biomarkers | cancer treatment | DNA damage response | 53BP1 | PARP-1 inhibitor | BRCA1 | parsylation | p53 | MRN complex | synthetic lethality or viability | Proteins | Binding | Landes | Calcium | Biology | Bioscience | Cell | Cycle | Organogenesis | Cancer | Cancer treatment | Predictive biomarkers | Synthetic lethality or viability | PARsylation | STRAND BREAK REPAIR | MRE11 | DNA-DAMAGE RESPONSE | POLY(ADP-RIBOSE) POLYMERASE INHIBITION | CELL BIOLOGY | MAMMARY-TUMORS | ADP-RIBOSE POLYMERASE | IN-VITRO ASSAYS | SYNTHETIC LETHALITY | TUMOR-SUPPRESSOR | HOMOLOGOUS RECOMBINATION | Neoplasms - metabolism | Humans | DNA Repair Enzymes - genetics | Gamma Rays - therapeutic use | Gene Expression Regulation, Neoplastic | Male | Intracellular Signaling Peptides and Proteins - metabolism | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Neoplasms - genetics | BRCA1 Protein - metabolism | DNA Repair Enzymes - metabolism | Biomarkers, Tumor - metabolism | Cell Cycle Proteins - genetics | Female | Antineoplastic Agents - pharmacology | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Recombinational DNA Repair - drug effects | Carcinoma - drug therapy | Genes, MDR | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Cell Cycle Proteins - metabolism | Enzyme Inhibitors - pharmacology | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Poly(ADP-ribose) Polymerase Inhibitors | Neoplasms - drug therapy | BRCA1 Protein - genetics | Drug Resistance, Neoplasm - genetics | Poly(ADP-ribose) Polymerases - metabolism | BRCA2 Protein - metabolism | Poly(ADP-ribose) Polymerases - genetics | Cell Line, Tumor | Recombinational DNA Repair - radiation effects | Biomarkers, Tumor - genetics | DNA Damage | Poly (ADP-Ribose) Polymerase-1 | Tumor Suppressor p53-Binding Protein 1 | Camptothecin - pharmacology | BRCA2 Protein - genetics | Index Medicus | Report
Journal Article