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1. Full Text Identification of PCDH1 as a Novel Susceptibility Gene for Bronchial Hyperresponsiveness
by Koppelman, Gerard H and Meyers, Deborah A and Howard, Timothy D and Zheng, S. Lilly and Hawkins, Greg A and Ampleford, Elizabeth J and Xu, Jianfeng and Koning, Henk and Bruinenberg, Marcel and Nolte, Ilja M and van Diemen, Cleo C and Boezen, H. Marike and Timens, Wim and Whittaker, Paul A and Stine, O. Colin and Barton, Sheila J and Holloway, John W and Holgate, Stephen T and Graves, Penelope E and Martinez, Fernando D and van Oosterhout, Antoon J and Bleecker, Eugene R and Postma, Dirkje S
American journal of respiratory and critical care medicine, ISSN 1073-449X, 11/2009, Volume 180, Issue 10, pp. 929 - 935
POPULATION | POSITIONAL CLONING | PEAK FLOW VARIABILITY | airway epithelium | CHILDHOOD | UMCG Approved | CHROMOSOME 5Q31-Q33 | cell adhesion | asthma genetics | ASTHMA | AIRWAY HYPERRESPONSIVENESS | bronchial hyperresponsiveness | LINKAGE | ASSOCIATION | protocadherin-1 | ATOPY | Protocadherin-1 | Bronchial hyperresponsiveness | Airway epithelium | Asthma genetics | Cell adhesion | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Cardiology. Vascular system | Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Biological and medical sciences | Intensive care medicine | Medical sciences | Blood and lymphatic vessels | Genetic Predisposition to Disease - genetics | Netherlands | United States | Humans | Adult | United Kingdom | Chromosome Mapping | Bronchial Hyperreactivity - genetics | Child | Asthma - genetics | Chromosomes, Human, Pair 5 | Genetic Linkage | Index Medicus | Abridged Index Medicus | B. Asthma and Allergy
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2. Full Text FUT2 Genetic Variants and Reported Respiratory and Gastrointestinal Illnesses During Infancy
by Barton, Sheila J and Murray, Robert and Lillycrop, Karen A and Inskip, Hazel M and Harvey, Nicholas C and Cooper, Cyrus and Karnani, Neerja and Zolezzi, Irma Silva and Sprenger, Norbert and Godfrey, Keith M and Binia, Aristea
The Journal of infectious diseases, ISSN 0022-1899, 02/2019, Volume 219, Issue 5, pp. 836 - 843
FUT2 variants | pediatric illnesses | gastrointestinal and respiratory illnesses | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fucosyltransferases - genetics | Genetic Predisposition to Disease | Humans | Diarrhea - epidemiology | Genotype | Infant | Male | Respiratory Tract Infections - genetics | Pregnancy | Diarrhea - genetics | Female | Polymorphism, Single Nucleotide | Respiratory Tract Infections - epidemiology | Infant, Newborn | Antigens | Breastfeeding & lactation | Linkage disequilibrium | Bronchopneumonia | Diarrhea | Infants | Single-nucleotide polymorphism | Breast feeding | Babies | Genetic variance | Respiratory diseases | Gastrointestinal diseases | Galactoside 2-a-L-fucosyltransferase | Alleles | Index Medicus | Abridged Index Medicus
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3. Full Text High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
by Eyre, Steve and Bowes, John and Diogo, Dorothee and Lee, Annette and Barton, Anne and Martin, Paul and Zhernakova, Alexana and Stahl, Eli and Viatte, Sebastien and McAllister, Kate and Amos, Christopher I and Padyukov, Leonid and Toes, Rene E. M and Huizinga, Tom W. J and Wijmenga, Cisca and Trynka, Gosia and Franke, Lude and Westra, Harm-Jan and Alfredsson, Lars and Hu, Xinli and Sandor, Cynthia and de Bakker, Paul I. W and Davila, Sonia and Khor, Chiea Chuen and Heng, Khai Koon and Anews, Robert and Edkins, Sarah and Hunt, Sarah E and Langford, Cordelia and Symmons, Deborah and Concannon, Pat and Onengut-Gumuscu, Suna and Rich, Stephen S and Deloukas, Panos and Gonzalez-Gay, Miguel A and Roiguez-Roiguez, Luis and Arlsetig, Lisbeth and Martin, Javier and Rantapaa-Dahlqvist, Solbritt and Plenge, Robert M and Raychaudhuri, Soumya and Klareskog, Lars and Gregersen, Peter K and Worthington, Jane and Biol Rheumatoid Arthrit Genetics G and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate
Nature genetics, ISSN 1061-4036, 12/2012, Volume 44, Issue 12, pp. 1336 - 1340
INTERLEUKIN-6 RECEPTOR | RISK LOCI | METAANALYSIS | CORONARY-HEART-DISEASE | EXPRESSION | ASSOCIATION | UMCG Approved | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Diseases of the osteoarticular system | Inflammatory joint diseases | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Methods, theories and miscellaneous | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Oligonucleotide Array Sequence Analysis | Autoantibodies - blood | Humans | Male | Genetic Loci | Chromosome Mapping - instrumentation | Arthritis, Rheumatoid - genetics | Chromosome Mapping - methods | Female | Polymorphism, Single Nucleotide | Autoantibodies - genetics | Rheumatoid arthritis | Physiological aspects | Genetic aspects | Disease susceptibility | Single nucleotide polymorphisms | Research | Chromosomes | Studies | Medical research | Autoimmune diseases | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D–Related Genetic Variants
by Moon, Rebecca J and Harvey, Nicholas C and Cooper, Cyrus and D’Angelo, Stefania and Curtis, Elizabeth M and Crozier, Sarah R and Barton, Sheila J and Robinson, Sian M and Godfrey, Keith M and Graham, Nikki J and Holloway, John W and Bishop, Nicholas J and Kennedy, Stephen and Papageorghiou, Aris T and Schoenmakers, Inez and Fraser, Robert and Gandhi, Saurabh V and Prentice, Ann and Inskip, Hazel M and Javaid, M Kassim and Maternal Vitamin D Osteopor and Maternal Vitamin D Osteoporosis Study Trial Group and the Maternal Vitamin D Osteoporosis Study Trial Group
The journal of clinical endocrinology and metabolism, ISSN 0021-972X, 08/2017, Volume 102, Issue 8, pp. 2941 - 2949
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Multivariate Analysis | Vitamin D3 24-Hydroxylase - genetics | Double-Blind Method | Humans | Genotype | Linear Models | Treatment Outcome | Vitamins - therapeutic use | Vitamin D - blood | Pregnancy | Young Adult | Vitamin D Deficiency - prevention & control | Vitamin D-Binding Protein - genetics | Cholestanetriol 26-Monooxygenase - genetics | Cholecalciferol - therapeutic use | Alleles | Cytochrome P450 Family 2 - genetics | Adult | Female | Oxidoreductases Acting on CH-CH Group Donors - genetics | Vitamin D - analogs & derivatives | Polymorphism, Single Nucleotide | Dietary Supplements | Statistical analysis | Hydroxylase | 7-Dehydrocholesterol reductase | Protein biosynthesis | Biosynthesis | Single-nucleotide polymorphism | Genetic diversity | Gestation | Regression analysis | Metabolism | Minority & ethnic groups | Confidence intervals | Osteoporosis | Genetic variance | Regression models | Biomedical materials | Randomization | Vitamin D | Metabolites | Protein synthesis | Biocompatibility | Supplementation | Polymorphism | 25-Hydroxyvitamin D | Index Medicus | Abridged Index Medicus
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5. Is cellular heterogeneity merely a confounder to be removed from epigenome-wide association studies?
by Holbrook, Joanna D and Huang, Rae-Chi and Barton, Sheila J and Saffery, Richard and Lillycrop, Karen A
Epigenomics, ISSN 1750-1911, 08/2017, Volume 9, Issue 8, pp. 1143 - 1150
DoHAD | epigenetic epidemiology | EWAS | biomarkers | cell fate | DNA methylation | cellular heterogeneity | epigenetics | methWAS | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | DNA Methylation | Animals | Epigenesis, Genetic | Humans | Genome-Wide Association Study - methods | Genome-Wide Association Study - standards | Genetic Heterogeneity
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6. Full Text Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes
by Eleftheria Zeggini and Michael N. Weedon and Cecilia M. Lindgren and Timothy M. Frayling and Katherine S. Elliott and Hana Lango and Nicholas J. Timpson and John R. B. Perry and Nigel W. Rayner and Rachel M. Freathy and Jeffrey C. Barrett and Beverley Shields and Andrew P. Morris and Sian Ellard and Christopher J. Groves and Lorna W. Harries and Jonathan L. Marchini and Katharine R. Owen and Beatrice Knight and Lon R. Cardon and Mark Walker and Graham A. Hitman and Andrew D. Morris and Alex S. F. Doney and Mark I. McCarthy and Andrew T. Hattersley and WTCCC and Wellcome Trust Case Control Consortium (WTCCC) and The Wellcome Trust Case Control Consortium (WTCCC)
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2007, Volume 316, Issue 5829, pp. 1336 - 1341
Medical research | Forestry research | Hospital buildings | Medical genetics | Genetic research | Hospital units | Genetic loci | Reports | Type 2 diabetes mellitus | Human genetics | Research universities | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Insulin-Like Growth Factor Binding Proteins - genetics | Genetic Predisposition to Disease | Meta-Analysis as Topic | Oligonucleotide Array Sequence Analysis | Introns | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | United Kingdom | Chromosome Mapping | Transcription Factors - genetics | Genes, p16 | Case-Control Studies | Homeodomain Proteins - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome, Human | Type 2 diabetes | Genetic aspects | Research | Risk factors | Biomedical research | Cellular biology | Genomics | Diabetes | Molecular biology | Pancreas | Population genetics | Index Medicus
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7. Full Text Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
by Clayton, David G and Duncanson, Audrey and Kwiatkowski, Dominic P and McCarthy, Mark I and Donnelly, Peter and Barrett, Jeffrey C and Easton, Doug and Evans, David and Leung, Hin-Tak and Spencer, Chris C. A and Tobin, Martin D and Boorman, James P and Everson, Ursula and Jolley, Jennifer D and Koch, Kerstin and Meech, Elizabeth and Nutland, Sarah and Stevens, Helen E and Jones, Richard W and McArdle, Wendy L and Strachan, David P and Breen, Gerome and Caesar, Sian and Gordon-Smith, Katherine and Jones, Lisa and Fraser, Christine and Hamshere, Marian L and Jones, Ian R and Kirov, George and Moskvina, Valentina and O'Donovan, Michael C and Owen, Michael J and Collier, David A and Elkin, Amanda and Farmer, Anne and Maqbool, Azhar and Yuldasheva, Nadira and Braund, Peter S and Dixon, Richard J and Thompson, John R and Bredin, Francesca and Parkes, Miles and Nimmo, Elaine R and Fisher, Sheila A and Forbes, Alastair and Prescott, Natalie J and Mathew, Christopher G and Barbour, Jamie and Mohiuddin, M. Khalid and Mansfield, John C and Webster, John and Brown, Morris J and Connell, John and Braga Marcano, Carolina A and Burke, Beverley and Dobson, Richard and Gungadoo, Johannie and Munroe, Patricia B and Newhouse, Stephen J and Onipinla, Abiodun and Wallace, Chris and Xue, Mingzhan and Barton, Anne and Eyre, Steve and Gilbert, Paul D and John, Sally L and Silman, Alan J and Thomson, Wendy and Worthington, Jane and Widmer, Barry and Freathy, Rachel M and Lango, Hana and Perry, John R.B and Weedon, Michael N and Hattersley, Andrew T and Hitman, Graham A and Walker, Mark and Lindgren, Cecilia M and Rayner, Nigel W and Newport, Melanie and Sirugo, Giorgio and Hill, Adrian V.S and Brown, Matthew A and Heward, Joanne M and Seal, Sheila and Conway, David and Jallow, Muminatou and Bumpstead, Suzannah J and Downes, Kate and Ghori, Mohammed J.R and Hunt, Sarah E and Inouye, Michael and Keniry, Andrew and King, Emma and Ravindrarajah, Rathi and Hallgrimsdóttir, Ingileif B and Howie, Bryan N and Spencer, Chris C.A and Su, Zhan and Teo, Yik Ying and Breast Canc Susceptib Collaborat and Wellcome Trust Case Control Cons and Biol RA Genet & Genom Study and Wellcome Trust Case Control Consortium and The Wellcome Trust Case Control Consortium
Nature (London), ISSN 0028-0836, 06/2007, Volume 447, Issue 7145, pp. 661 - 678
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Human | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Geography | Crohn Disease - genetics | Genetics, Population | Genetic Predisposition to Disease - genetics | Diabetes Mellitus - genetics | Chromosomes, Human - genetics | Gene Frequency | Humans | United Kingdom | Bipolar Disorder - genetics | Case-Control Studies | Genome, Human - genetics | Arthritis, Rheumatoid - genetics | Genetic Markers - genetics | Coronary Artery Disease - genetics | Hypertension - genetics | Data analysis | Disease | Genomics | Data collection | Gene loci | Epidemiology | Risk factors | Index Medicus
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