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1. Full Text Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
by Vijayakrishnan, Jayaram and Studd, James and Broderick, Peter and Kinnersley, Ben and Holroyd, Amy and Law, Philip J and Kumar, Rajiv and Allan, James M and Harrison, Christine J and Moorman, Anthony V and Vora, Ajay and Roman, Eve and Rachakonda, Sivaramakrishna and Kinsey, Sally E and Sheridan, Eamonn and Thompson, Pamela D and Irving, Julie A and Koehler, Rolf and Hoffmann, Per and Nöthen, Markus M and Heilmann-Heimbach, Stefanie and Jöckel, Karl-Heinz and Easton, Douglas F and Pharaoh, Paul D. P and Dunning, Alison M and Peto, Julian and Canzian, Frederico and Swerdlow, Anthony and Eeles, Rosalind A and Kote-Jarai, ZSofia and Muir, Kenneth and Pashayan, Nora and Greaves, Mel and Zimmerman, Martin and Bartram, Claus R and Schrappe, Martin and Stanulla, Martin and Hemminki, Kari and Houlston, Richard S and The PRACTICAL Consortium and PRACTICAL Consortium
Nature communications, ISSN 2041-1723, 04/2018, Volume 9, Issue 1, pp. 1340 - 9
... Swerdlow1,19, Rosalind A. Eeles 1,20, ZSofia Kote-Jarai1, Kenneth Muir 21,22, Nora Pashayan 15,23, The PRACTICAL consortium, Mel Greaves24, Martin Zimmerman25, Claus R... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Prognosis | Humans | Risk Factors | Child, Preschool | Male | HLA Antigens - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - immunology | Oncogene Proteins, Fusion - genetics | Female | Polymorphism, Single Nucleotide | Glycosyltransferases - genetics | Child | Core Binding Factor Alpha 2 Subunit - genetics | Acute lymphatic leukemia | Lymphocytes B | Leukemia | Chromosome 8 | Runx1 protein | Genomes | Children | Lymphatic leukemia | Risk management | Loci | Index Medicus | Clinical Medicine | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Cancer and Oncology | Cancer och onkologi
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2. Full Text Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: Results in 3184 patients of the AIEOP-BFMALL 2000 study
by Conter, V and Bartram, Claus and Valsecchi, Maria Grazia and Schrauder, Ané and Panzer-Grümayer, Renate and Möricke, A and Aricò, Maurizio and Zimmermann, Martin and Mann, Georg and Rossi, Giulio and Stanulla, Martin and Locatelli, Franco and Basso, Giuseppe and Niggli, Felix and Barisone, Elena and Henze, Günter and Ludwig, W.D and Haas, Oskar and Cazzaniga, Gianni and Koehler, Rolf and Silvestri, Daniela and Bradtke, Jutta and Parasole, Rosanna and Beier, Rita and Dongen, Jacques and Biondi, Anea and Schrappe, Martin
Blood, ISSN 0006-4971, 04/2010, Volume 115, Issue 16, pp. 3206 - 3214
textabstractThe Associazione Italiana di Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Münster Acute Lymphoblastic Leukemia (AIEOP-BFM ALL 2000)... 
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3. Full Text IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol
by Petra Dörge and Barbara Meissner and Martin Zimmermann and Anja Möricke and André Schrauder and Jean-Pierre Bouquin and Denis Schewe and Jochen Harbott and Andrea Teigler-Schlegel and Richard Ratei and Wolf-Dieter Ludwig and Rolf Koehler and Claus R. Bartram and Martin Schrappe and Martin Stanulla and Gunnar Cario
Haematologica, ISSN 0390-6078, 03/2013, Volume 98, Issue 3, pp. 428 - 432
IKZF1 gene deletions have been associated with a poor outcome in pediatric precursor B-cell acute lymphoblastic leukemia. To assess the prognostic relevance of... 
Life Sciences & Biomedicine | Hematology | Science & Technology | Prognosis | Humans | Child, Preschool | Infant | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Treatment Outcome | Ikaros Transcription Factor - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Gene Deletion | Female | Child | Index Medicus
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4. Full Text Should donors be allowed to give broad consent to future biobank research?
by Hansson, Mats G and Dillner, Joakim and Bartram, Claus R and Carlson, Joyce A and Helgesson, Gert
The lancet oncology, ISSN 1470-2045, 03/2006, Volume 7, Issue 3, pp. 266 - 269
Large international biobank studies can make substantial contributions to scientific research by validation of the biological importance of previous research... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Ethics, Medical | Informed Consent | Genetic Predisposition to Disease | Tissue Banks - ethics | Confidentiality | Humans | Research | Tissue Donors | Index Medicus | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
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5. Full Text Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study
by Schrappe, Martin and Valsecchi, Maria Grazia and Bartram, Claus R and Schrauder, André and Panzer-Grümayer, Renate and Möricke, Anja and Parasole, Rosanna and Zimmermann, Martin and Dworzak, Michael and Buldini, Barbara and Reiter, Alfred and Basso, Giuseppe and Klingebiel, Thomas and Messina, Chiara and Ratei, Richard and Cazzaniga, Giovanni and Koehler, Rolf and Locatelli, Franco and Schäfer, Beat W and Aricò, Maurizio and Welte, Karl and van Dongen, Jacques J.M and Gadner, Helmut and Biondi, Andrea and Conter, Valentino
Blood, ISSN 1528-0020, 08/2011, Volume 118, Issue 8, pp. 2077 - 2084
The prognostic value of MRD in large series of childhood T-ALL has not yet been established. Trial AIEOP-BFM-ALL 2000 introduced standardized quantitative... 
Life Sciences & Biomedicine | Hematology | Science & Technology | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Prognosis | Prospective Studies | Gene Rearrangement, T-Lymphocyte | Humans | Risk Factors | Antineoplastic Combined Chemotherapy Protocols | Child, Preschool | Infant | Male | Neoplasm, Residual | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - immunology | Disease-Free Survival | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Time Factors | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Adolescent | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - classification | Female | Gene Rearrangement, B-Lymphocyte | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - immunology | Child | Index Medicus | Abridged Index Medicus
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6. Full Text A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk
by Yang, Rongxi and Schlehe, Bettina and Hemminki, Kari and Sutter, Christian and Bugert, Peter and Wappenschmidt, Barbara and Volkmann, Juliane and Varon, Raymonda and Weber, Bernhard H. F and Niederacher, Dieter and Arnold, Norbert and Meindl, Alfons and Bartram, Claus R and Schmutzler, Rita K and Burwinkel, Barbara
Breast cancer research and treatment, ISSN 1573-7217, 11/2009, Volume 121, Issue 3, pp. 693 - 702
... • Alfons Meindl • Claus R. Bartram • Rita K. Schmutzler • Barbara Burwinkel Received: 30 July 2009 / Accepted: 30 October 2009 / Published online: 18 November 2009... 
Breast cancer risk | Oncology | MicroRNA | Medicine & Public Health | SNP | Case–control study | Case-control study | Life Sciences & Biomedicine | Science & Technology | Genetic Predisposition to Disease - genetics | Age Distribution | Humans | Middle Aged | Family Health | Case-Control Studies | Germany - epidemiology | Breast Neoplasms - genetics | Aged, 80 and over | Adult | Female | Aged | MicroRNAs - genetics | Polymorphism, Single Nucleotide | Breast Neoplasms - epidemiology | Prevention | Breast cancer | Genetic aspects | Health aspects | Chromosomes | Risk factors | Cancer | Index Medicus
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7. Full Text Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history
by Engel, Christoph and Rhiem, Kerstin and Hahnen, Eric and Loibl, Sibylle and Weber, Karsten E and Seiler, Sabine and Zachariae, Silke and Hauke, Jan and Wappenschmidt, Barbara and Waha, Anke and Blümcke, Britta and Kiechle, Marion and Meindl, Alfons and Niederacher, Dieter and Bartram, Claus R and Speiser, Dorothee and Schlegelberger, Brigitte and Arnold, Norbert and Wieacker, Peter and Leinert, Elena and Gehrig, Andrea and Briest, Susanne and Kast, Karin and Riess, Olaf and Emons, Günter and Weber, Bernhard H. F and Engel, Jutta and Schmutzler, Rita K and on behalf of the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) and German Consortium Hereditary Breas and German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC)
BMC cancer, ISSN 1471-2407, 03/2018, Volume 18, Issue 1, pp. 265 - 265
... Niederacher[sup.6], Claus R. Bartram[sup.7], Dorothee Speiser[sup.8], Brigitte Schlegelberger[sup.9], Norbert Arnold[sup.10], Peter Wieacker[sup.11], Elena Leinert[sup.12... 
BRCA1 | BRCA2 | Hereditary breast and ovarian cancer | Triple-negative breast cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Women | Research | Gene mutations | History | Health aspects | Prevalence studies (Epidemiology) | Index Medicus
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8. Full Text The E. coli molecular phenotype under different growth conditions
by Caglar, Mehmet U and Houser, John R and Barnhart, Craig S and Boutz, Daniel R and Carroll, Sean M and Dasgupta, Aurko and Lenoir, Walter F and Smith, Bartram L and Sridhara, Viswanadham and Sydykova, Dariya K and Vander Wood, Drew and Marx, Christopher J and Marcotte, Edward M and Barrick, Jeffrey E and Wilke, Claus O
Scientific reports, ISSN 2045-2322, 04/2017, Volume 7, Issue 1, pp. 45303 - 45303
... Mehmet U. Caglar1,2,3, John R. Houser3,4,5, Craig S. Barnhart3,4, Daniel R. Boutz3,4,5, Sean M. Carroll6,7, Aurko Dasgupta3,4,8, Walter F. Lenoir5, Bartram L... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Carbon - metabolism | Phenotype | Escherichia coli - genetics | Escherichia coli Proteins - genetics | Bacteriological Techniques | Escherichia coli Proteins - metabolism | Magnesium - metabolism | Escherichia coli - growth & development | Sodium - metabolism | Culture Media - chemistry | Gene Expression Regulation, Bacterial | Growth conditions | Transcription | Gene regulation | Glycerol | Genomes | Carbon | Environmental conditions | Sodium | E coli | Computer applications | Proteomics | Lactic acid | Magnesium | Carbon sources | Stationary phase | Index Medicus
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9. Full Text Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
by Waszak, Sebastian M and Northcott, Paul A and Buchhalter, Ivo and Robinson, Giles W and Sutter, Christian and Groebner, Susanne and Grund, Kerstin B and Brugières, Laurence and Jones, David T W and Pajtler, Kristian W and Morrissy, A Sorana and Kool, Marcel and Sturm, Dominik and Chavez, Lukas and Ernst, Aurelie and Brabetz, Sebastian and Hain, Michael and Zichner, Thomas and Segura-Wang, Maia and Weischenfeldt, Joachim and Rausch, Tobias and Mardin, Balca R and Zhou, Xin and Baciu, Cristina and Lawerenz, Christian and Chan, Jennifer A and Varlet, Pascale and Guerrini-Rousseau, Lea and Fults, Daniel W and Grajkowska, Wiesława and Hauser, Peter and Jabado, Nada and Ra, Young-Shin and Zitterbart, Karel and Shringarpure, Suyash S and De La Vega, Francisco M and Bustamante, Carlos D and Ng, Ho-Keung and Perry, Arie and MacDonald, Tobey J and Hernáiz Driever, Pablo and Bendel, Anne E and Bowers, Daniel C and McCowage, Geoffrey and Chintagumpala, Murali M and Cohn, Richard and Hassall, Timothy and Fleischhack, Gudrun and Eggen, Tone and Wesenberg, Finn and Feychting, Maria and Lannering, Birgitta and Schüz, Joachim and Johansen, Christoffer and Andersen, Tina V and Röösli, Martin and Kuehni, Claudia E and Grotzer, Michael and Kjaerheim, Kristina and Monoranu, Camelia M and Archer, Tenley C and Duke, Elizabeth and Pomeroy, Scott L and Shelagh, Redmond and Frank, Stephan and Sumerauer, David and Scheurlen, Wolfram and Ryzhova, Marina V and Milde, Till and Kratz, Christian P and Samuel, David and Zhang, Jinghui and Solomon, David A and Marra, Marco and Eils, Roland and Bartram, Claus R and von Hoff, Katja and Rutkowski, Stefan and Ramaswamy, Vijay and Gilbertson, Richard J and Korshunov, Andrey and Taylor, Michael D and Lichter, Peter and Malkin, David and Gajjar, Amar and Korbel, Jan O and Pfister, Stefan M and Sahlgrenska akademin and Institute of Clinical Sciences, Department of Pediatrics and Göteborgs universitet and Gothenburg University and Institutionen för kliniska vetenskaper, Avdelningen för pediatrik and Sahlgrenska Academy
The lancet oncology, ISSN 1470-2045, 06/2018, Volume 19, Issue 6, pp. 785 - 798
Medulloblastoma is associated with rare hereditary cancer predisposition syndromes; however, consensus medulloblastoma predisposition genes have not been... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Medicine, Experimental | Genetic research | Clinical trials | Medical research | Medulloblastoma | Index Medicus | fanconi-anemia | breast-cancer | tp53 | somatic mutations | mutation | subgroups | palb2 | brain-tumors | children | childhood-cancer | Cancer and Oncology | landscape | Cancer och onkologi
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10. Full Text Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000
by Möricke, Anja and Zimmermann, Martin and Valsecchi, Maria Grazia and Stanulla, Martin and Biondi, Andrea and Mann, Georg and Locatelli, Franco and Cazzaniga, Giovanni and Niggli, Felix and Aricò, Maurizio and Bartram, Claus R and Attarbaschi, Andishe and Silvestri, Daniela and Beier, Rita and Basso, Giuseppe and Ratei, Richard and Kulozik, Andreas E and Lo Nigro, Luca and Kremens, Bernhard and Greiner, Jeanette and Parasole, Rosanna and Harbott, Jochen and Caruso, Roberta and von Stackelberg, Arend and Barisone, Elena and Rössig, Claudia and Conter, Valentino and Schrappe, Martin
Blood, ISSN 1528-0020, 04/2016, Volume 127, Issue 17, pp. 2101 - 2112
Dexamethasone vs prednisone in induction of pediatric ALL led to significant relapse reduction and increased treatment-related mortality. No overall survival... 
Life Sciences & Biomedicine | Hematology | Science & Technology | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Prednisone - administration & dosage | Dexamethasone - administration & dosage | Humans | Kaplan-Meier Estimate | Proportional Hazards Models | Child, Preschool | Hematopoietic Stem Cell Transplantation | Infant | Male | Treatment Outcome | Combined Modality Therapy | Cranial Irradiation | Remission Induction | Dexamethasone - pharmacokinetics | Neoplasm, Residual | Disease-Free Survival | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Female | Methotrexate - administration & dosage | Child | Index Medicus | Abridged Index Medicus
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