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International Journal of Cancer, ISSN 0020-7136, 05/2019, Volume 144, Issue 10, pp. 2567 - 2577
Journal Article
Cancer, ISSN 0008-543X, 11/2017, Volume 123, Issue 22, pp. 4506 - 4514
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2017, Volume 141, Issue 2, pp. 383 - 392
The Insulin‐like growth factor (IGF)/IGF‐receptor pathway with its scaffolding proteins Insulin Receptor Substrate (IRS)1 and IRS2 are crucial regulators of... 
metastatic colorectal cancer | IGF | IRS | SNP | RAS | PHASE-II | MONOCLONAL-ANTIBODY | METASTATIC COLORECTAL-CANCER | INSULIN-RECEPTORS | POSITIVE BREAST-CANCER | CELL LUNG-CANCER | GROWTH-FACTOR RECEPTOR | CETUXIMAB | ONCOLOGY | FACTOR-I RECEPTOR | TYPE-2 DIABETES-MELLITUS | Bevacizumab - therapeutic use | Prognosis | Camptothecin - therapeutic use | Signal Transduction | Colorectal Neoplasms - genetics | Humans | Genetic Association Studies - methods | Male | Cetuximab - therapeutic use | Sequence Analysis, DNA | Fluorouracil - therapeutic use | Neoplasm Metastasis | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Colorectal Neoplasms - drug therapy | Somatomedins - genetics | Survival Analysis | Female | Leucovorin - therapeutic use | Polymorphism, Single Nucleotide | Insulin Receptor Substrate Proteins - genetics | Camptothecin - analogs & derivatives | Proteins | Medical research | Analysis | Patient outcomes | Colorectal cancer | Physiological aspects | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Metastasis | Chromosomes | Drugs | Regulators | Insulin-like growth factor I | Tumor cells | Test procedures | Genes | Colorectal carcinoma | Markers | Ras protein | Insulin-like growth factors | Single-nucleotide polymorphism | Metabolism | Insulin | Survival | Patients | Metastases | Carriers | Polymerase chain reaction | Signal transduction | Scaffolding | Cancer
Journal Article
Pharmacogenomics Journal, ISSN 1470-269X, 09/2018, Volume 18, Issue 5, pp. 623 - 632
Journal Article
European Journal of Cancer, ISSN 0959-8049, 11/2017, Volume 86, pp. 197 - 206
Trifluridine (FTD) is an active cytotoxic component of the metastatic colorectal cancer (mCRC) drug TAS-102, and thymidine phosphorylase inhibitor (TPI)... 
TAS-102 | Trifluridine | Thymidine phosphorylase inhibitor | Transporter | Metastatic colorectal cancer | THYMIDINE KINASE | METFORMIN | CELLS | SOLID TUMORS | TRIFLUOROTHYMIDINE | NUCLEOSIDE TRANSPORTERS | 5-FLUOROURACIL | ONCOLOGY | OCT2 | RESISTANCE | PHASE-I | Predictive Value of Tests | Colorectal Neoplasms - genetics | Humans | Organic Cation Transporter 2 - metabolism | Male | Antineoplastic Agents - therapeutic use | Trifluridine - pharmacokinetics | Neoplasm Metastasis | Antineoplastic Agents - adverse effects | Colorectal Neoplasms - drug therapy | Pharmacogenomic Variants | Female | Antineoplastic Agents - pharmacokinetics | Retrospective Studies | Pharmacogenetics | Organic Cation Transport Proteins - metabolism | Gene Frequency | Japan | Equilibrative Nucleoside Transporter 1 - genetics | Uracil - therapeutic use | Genotype | Treatment Outcome | Equilibrative Nucleoside Transporter 1 - metabolism | California | Pharmacogenomic Testing | Trifluridine - therapeutic use | Disease-Free Survival | Phenotype | Uracil - adverse effects | Trifluridine - adverse effects | Italy | Polymorphism, Single Nucleotide | Colorectal Neoplasms - pathology | Organic Cation Transport Proteins - genetics | Uracil - pharmacokinetics | Organic Cation Transporter 2 - genetics | Drug Combinations | Uracil - analogs & derivatives | Cancer patients | Genes | Colorectal cancer | Nucleosides | Physiological aspects | Genetic research | Genetic aspects | Single nucleotide polymorphisms | Metastasis
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 10/2015, Volume 14, Issue 10, pp. 2401 - 2408
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2017, Volume 23, Issue 14, pp. 3657 - 3666
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 07/2018, Volume 8, p. 259
Liquid biopsies are increasingly used in the care of patients with advanced cancers. These tests are used to find mutations and other genomic alterations,... 
Cell-free DNA | Germline mutation | Liquid biopsy | Hereditary cancer syndromes | Pancreaticobiliary neoplasms | CLINICAL-ONCOLOGY | PREVALENCE | BRCA2 | germline mutation | BREAST-CANCER | ONCOLOGY | hereditary cancer syndromes | cell-free DNA | UPDATE | MUTATIONS | POLICY STATEMENT | TUMOR DNA | liquid biopsy | pancreaticobiliary neoplasms | AMERICAN-SOCIETY
Journal Article
Cancer, ISSN 0008-543X, 10/2017, Volume 123, Issue 19, pp. 3732 - 3743
BACKGROUND The landscape of hereditary syndromes and clinicopathologic characteristics among US Latino/Hispanic individuals with colorectal cancer (CRC)... 
microsatellite instability (MSI) | colorectal cancer | Hispanic | Latino | DNA mismatch repair | Lynch syndrome | UNITED-STATES | SURVIVAL | LYNCH-SYNDROME | MICROSATELLITE INSTABILITY | MSH2 MUTATIONS | COLON | RACIAL DISPARITIES | MORTALITY-RATES | ONCOLOGY | FAMILIES | HISPANICS | Colorectal Neoplasms - epidemiology | Immunohistochemistry | Hispanic Americans - genetics | Microsatellite Instability | Prevalence | Age Factors | Colorectal Neoplasms - ethnology | California - epidemiology | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Middle Aged | Risk Factors | Male | MutS Homolog 2 Protein - genetics | DNA-Binding Proteins - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - epidemiology | DNA Mismatch Repair | MutL Protein Homolog 1 - genetics | Sex Factors | Family | Female | Mismatch Repair Endonuclease PMS2 - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - ethnology | Care and treatment | Genetic aspects | Research | Gene mutations | Colorectal cancer | Yeast | Colorectal carcinoma | Hispanic Americans | Disorders | Medical records | Charts | Homology | Microsatellite instability | DNA repair | Genetic screening | Risk factors | Mismatch repair | Genetics | Diagnosis | Repair | Deoxyribonucleic acid--DNA | Microsatellites | Stability | MLH1 protein | MSH2 protein | Health risks | Risk analysis | Patients | Polyposis | Current carriers | Mutation | Genetic recombination | Tumors | Cancer | Original
Journal Article
Urologic Oncology: Seminars and Original Investigations, ISSN 1078-1439, 2017, Volume 35, Issue 7, pp. 459.e15 - 459.e24
Journal Article