2009, 2nd ed., ISBN 0763757071, vi, 144
Book
2002, Cancer treatment and research, ISBN 0792376463, Volume 110, x, 216
Book
Journal of Clinical Oncology, ISSN 0732-183X, 04/2013, Volume 31, Issue 10, pp. 1310 - 1316
Purpose T-cell-replete grafts from haploidentical donors using post-transplantation cyclophosphamide may represent a solution for patients who require...
ACUTE-LEUKEMIA | TRIALS | ONCOLOGY | BONE-MARROW-TRANSPLANTATION | HIGH-RISK | PERIPHERAL-BLOOD | ADJUSTED SURVIVAL CURVES | Hematologic Neoplasms - therapy | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Graft vs Host Disease - immunology | Cyclophosphamide - therapeutic use | Transplantation, Homologous | Blood Donors | Postoperative Care | Hematopoietic Stem Cell Transplantation - adverse effects | Female | Unrelated Donors | Graft vs Host Disease - etiology | Siblings | Proportional Hazards Models | HLA Antigens - immunology | Cyclophosphamide - immunology | Disease-Free Survival | Outcome Assessment (Health Care) - statistics & numerical data | Immunosuppressive Agents - immunology | Graft vs Host Disease - prevention & control | T-Lymphocytes - immunology | Hematologic Neoplasms - immunology | Hematopoietic Stem Cell Transplantation - methods
ACUTE-LEUKEMIA | TRIALS | ONCOLOGY | BONE-MARROW-TRANSPLANTATION | HIGH-RISK | PERIPHERAL-BLOOD | ADJUSTED SURVIVAL CURVES | Hematologic Neoplasms - therapy | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Graft vs Host Disease - immunology | Cyclophosphamide - therapeutic use | Transplantation, Homologous | Blood Donors | Postoperative Care | Hematopoietic Stem Cell Transplantation - adverse effects | Female | Unrelated Donors | Graft vs Host Disease - etiology | Siblings | Proportional Hazards Models | HLA Antigens - immunology | Cyclophosphamide - immunology | Disease-Free Survival | Outcome Assessment (Health Care) - statistics & numerical data | Immunosuppressive Agents - immunology | Graft vs Host Disease - prevention & control | T-Lymphocytes - immunology | Hematologic Neoplasms - immunology | Hematopoietic Stem Cell Transplantation - methods
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2014, Volume 20, Issue 5, pp. 598 - 599
Hematology, Oncology and Palliative Medicine | SURVIVAL | ACUTE-LEUKEMIA | RELAPSE | BONE-MARROW-TRANSPLANTATION | HIGH-RISK | PHASE-II | DONORS | OUTCOMES | IMMUNOLOGY | HEMATOLOGY | HEMATOLOGIC MALIGNANCIES | TRANSPLANTATION | Antineoplastic Agents, Alkylating - therapeutic use | T-Lymphocytes - cytology | Humans | Graft vs Host Disease - prevention & control | T-Lymphocytes - immunology | Hematopoietic Stem Cell Mobilization | Lymphocyte Depletion | Transplantation Conditioning | Peripheral Blood Stem Cell Transplantation | Cyclophosphamide - therapeutic use | Graft vs Host Disease - pathology
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2012, Volume 366, Issue 19, pp. 1770 - 1781
In patients who had undergone stem-cell transplantation, lenalidomide maintenance therapy improved progression-free and overall survival, though at the expense...
INTERGROUPE FRANCOPHONE | MAINTENANCE | MEDICINE, GENERAL & INTERNAL | DEXAMETHASONE | PREDNISONE | RESPONSE CRITERIA | CONSOLIDATION THERAPY | IMPROVES SURVIVAL | THALIDOMIDE | BORTEZOMIB | LEUKEMIA | Thalidomide - adverse effects | Double-Blind Method | Follow-Up Studies | Multiple Myeloma - mortality | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Neoplasms, Second Primary - epidemiology | Stem Cell Transplantation | Disease-Free Survival | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Multiple Myeloma - therapy | Antineoplastic Agents - adverse effects | Adult | Female | Aged | Maintenance Chemotherapy | Thalidomide - therapeutic use | Drugs | Dose-response relationship (Biochemistry) | Care and treatment | Usage | Multiple myeloma | Stem cells | Product/Service Evaluations | Transplantation | Drug therapy | Autografts | Transplants & implants | Toxicity | Clinical trials | Stem cell transplantation | Cancer therapies | Cancer | Hemopoiesis | Index Medicus | Abridged Index Medicus
INTERGROUPE FRANCOPHONE | MAINTENANCE | MEDICINE, GENERAL & INTERNAL | DEXAMETHASONE | PREDNISONE | RESPONSE CRITERIA | CONSOLIDATION THERAPY | IMPROVES SURVIVAL | THALIDOMIDE | BORTEZOMIB | LEUKEMIA | Thalidomide - adverse effects | Double-Blind Method | Follow-Up Studies | Multiple Myeloma - mortality | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Neoplasms, Second Primary - epidemiology | Stem Cell Transplantation | Disease-Free Survival | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Multiple Myeloma - therapy | Antineoplastic Agents - adverse effects | Adult | Female | Aged | Maintenance Chemotherapy | Thalidomide - therapeutic use | Drugs | Dose-response relationship (Biochemistry) | Care and treatment | Usage | Multiple myeloma | Stem cells | Product/Service Evaluations | Transplantation | Drug therapy | Autografts | Transplants & implants | Toxicity | Clinical trials | Stem cell transplantation | Cancer therapies | Cancer | Hemopoiesis | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2016, Volume 375, Issue 2, pp. 143 - 153
Hematologic cancers that recur after allogeneic hematopoietic stem-cell transplantation are often difficult to treat. A small pilot study suggests that...
MEDICINE, GENERAL & INTERNAL | PATTERN | CTLA-4 | ACUTE MYELOID-LEUKEMIA | STEM-CELL TRANSPLANTATION | BLOCKADE | HLA | VERSUS-HOST-DISEASE | HEMATOLOGIC MALIGNANCIES | T-CELLS | Hematologic Neoplasms - therapy | Recurrence | Myeloproliferative Disorders - therapy | Humans | Ipilimumab | Middle Aged | Antibodies, Monoclonal - adverse effects | Hematopoietic Stem Cell Transplantation | Leukemia - therapy | Antibodies, Monoclonal - therapeutic use | Induction Chemotherapy | Male | CD4 Lymphocyte Count | Hematologic Neoplasms - pathology | Transplantation, Homologous | Lymphoma - therapy | T-Lymphocytes, Regulatory | Adult | Female | Transplantation Immunology | Aged | Subpopulations | Graft-versus-host reaction | Immunoregulation | Myeloid leukemia | CD8 antigen | Body weight | Effector cells | Stem cell transplantation | Cytotoxicity | Lymphocytes T | Myelodysplastic syndrome | Hemopoiesis | Metastases | Cell activation | Immune checkpoint | Antitumor activity | Ligands | Lymphomas | Pharmaceutical industry | Acute myeloid leukemia | Cancer | Index Medicus | Abridged Index Medicus
MEDICINE, GENERAL & INTERNAL | PATTERN | CTLA-4 | ACUTE MYELOID-LEUKEMIA | STEM-CELL TRANSPLANTATION | BLOCKADE | HLA | VERSUS-HOST-DISEASE | HEMATOLOGIC MALIGNANCIES | T-CELLS | Hematologic Neoplasms - therapy | Recurrence | Myeloproliferative Disorders - therapy | Humans | Ipilimumab | Middle Aged | Antibodies, Monoclonal - adverse effects | Hematopoietic Stem Cell Transplantation | Leukemia - therapy | Antibodies, Monoclonal - therapeutic use | Induction Chemotherapy | Male | CD4 Lymphocyte Count | Hematologic Neoplasms - pathology | Transplantation, Homologous | Lymphoma - therapy | T-Lymphocytes, Regulatory | Adult | Female | Transplantation Immunology | Aged | Subpopulations | Graft-versus-host reaction | Immunoregulation | Myeloid leukemia | CD8 antigen | Body weight | Effector cells | Stem cell transplantation | Cytotoxicity | Lymphocytes T | Myelodysplastic syndrome | Hemopoiesis | Metastases | Cell activation | Immune checkpoint | Antitumor activity | Ligands | Lymphomas | Pharmaceutical industry | Acute myeloid leukemia | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Bone Marrow Transplantation, ISSN 0268-3369, 06/2018, Volume 53, Issue 6, pp. 756 - 763
Allografting from HLA-haploidentical donors (HID) is being increasingly utilized worldwide for patients lacking a conventional matched donor. However, its...
DISEASE RISK INDEX | MYELODYSPLASTIC SYNDROME MDS | GRAFTS | BONE-MARROW-TRANSPLANTATION | ACUTE MYELOID-LEUKEMIA | IMMUNOLOGY | 1ST COMPLETE REMISSION | TRANSPLANTATION | ONCOLOGY | STEM-CELL TRANSPLANTATION | HEMATOLOGY | ELDERLY-PATIENTS | HEMATOLOGIC MALIGNANCIES | BLOOD | Leukemia, Myeloid, Acute - pathology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Cyclophosphamide - therapeutic use | Myelodysplastic Syndromes - therapy | Cyclophosphamide - pharmacology | Leukemia, Myeloid, Acute - drug therapy | Female | Unrelated Donors | Aged | Hematopoietic Stem Cell Transplantation - methods | Tissue Donors | Transplantation Conditioning - methods | Myelodysplastic Syndromes - pathology | Immunosuppressive Agents - pharmacology | Leukemia, Myeloid, Acute - therapy | Myelodysplastic Syndromes - drug therapy | Medical research | Cyclophosphamide | Usage | Analysis | Medicine, Experimental | Bone marrow | Transplantation | Research | Bone grafts | Graft-versus-host reaction | Transplants & implants | Health risks | Transplants | Gender | Survival | Patients | Direct reduced iron | Donors | Histocompatibility antigen HLA | Mud
DISEASE RISK INDEX | MYELODYSPLASTIC SYNDROME MDS | GRAFTS | BONE-MARROW-TRANSPLANTATION | ACUTE MYELOID-LEUKEMIA | IMMUNOLOGY | 1ST COMPLETE REMISSION | TRANSPLANTATION | ONCOLOGY | STEM-CELL TRANSPLANTATION | HEMATOLOGY | ELDERLY-PATIENTS | HEMATOLOGIC MALIGNANCIES | BLOOD | Leukemia, Myeloid, Acute - pathology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Cyclophosphamide - therapeutic use | Myelodysplastic Syndromes - therapy | Cyclophosphamide - pharmacology | Leukemia, Myeloid, Acute - drug therapy | Female | Unrelated Donors | Aged | Hematopoietic Stem Cell Transplantation - methods | Tissue Donors | Transplantation Conditioning - methods | Myelodysplastic Syndromes - pathology | Immunosuppressive Agents - pharmacology | Leukemia, Myeloid, Acute - therapy | Myelodysplastic Syndromes - drug therapy | Medical research | Cyclophosphamide | Usage | Analysis | Medicine, Experimental | Bone marrow | Transplantation | Research | Bone grafts | Graft-versus-host reaction | Transplants & implants | Health risks | Transplants | Gender | Survival | Patients | Direct reduced iron | Donors | Histocompatibility antigen HLA | Mud
Journal Article
BONE MARROW TRANSPLANTATION, ISSN 0268-3369, 11/2019, Volume 54, Issue 11, pp. 1756 - 1763
Fever is a common early complication after infusion of stem cells in patients undergoing T-replete HLA haploidentical transplantation using post-transplant...
CYTOKINE-RELEASE SYNDROME | TOTAL-BODY IRRADIATION | SURVIVAL | BONE-MARROW | PERIPHERAL-BLOOD | SAFE | IMMUNOLOGY | 2-STEP APPROACH | TRANSPLANTATION | THERAPY | ONCOLOGY | DONOR TRANSPLANTATION | HEMATOLOGY | CD34 antigen | Graft-versus-host reaction | Transplants & implants | Mortality | Stem cell transplantation | Transplantation | Lymphocytes T | CD3 antigen | Regression analysis | Risk analysis | Morbidity | Fever | Hematopoietic stem cells | Risk factors | Hemopoiesis | Infusion | Cyclophosphamide | Grafts | Stem cells | Histocompatibility antigen HLA
CYTOKINE-RELEASE SYNDROME | TOTAL-BODY IRRADIATION | SURVIVAL | BONE-MARROW | PERIPHERAL-BLOOD | SAFE | IMMUNOLOGY | 2-STEP APPROACH | TRANSPLANTATION | THERAPY | ONCOLOGY | DONOR TRANSPLANTATION | HEMATOLOGY | CD34 antigen | Graft-versus-host reaction | Transplants & implants | Mortality | Stem cell transplantation | Transplantation | Lymphocytes T | CD3 antigen | Regression analysis | Risk analysis | Morbidity | Fever | Hematopoietic stem cells | Risk factors | Hemopoiesis | Infusion | Cyclophosphamide | Grafts | Stem cells | Histocompatibility antigen HLA
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 3333 - 3333
HLA-haploidentical (haplo) stem cell transplantation is now widely used for patients lacking a suitably matched related or unrelated donor (MUD)....
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 4541 - 4541
Unmanipulated T-cell replete HLA-mismatched haploidentical transplantation (haplo) with post-transplant cyclophosphamide (PTCY) is now widely used for patients...
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 4479 - 4479
Phase II trial evaluating the Efficacy and Safety of Sargramostim Post Infusion of T -Replete HLA Mismatched Peripheral Blood Haploidentical Hematopoietic Stem...
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2014 - 2014
Relapse of leukemia (RL) is the most common cause of treatment failure following allogeneic hematopoietic cell transplantation (alloHCT) in patients with AML....
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2006 - 2006
Severe (grade 3-4) acute GVHD (aGVHD) and NIH grade severe chronic GVHD (cGVHD) have historically been associated with poor survival. However, earlier...
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 04/2017, Volume 35, Issue 11, pp. 1154 - 1161
Journal Article
Bone Marrow Transplantation, ISSN 0268-3369, 05/2018, Volume 53, Issue 5, pp. 576 - 583
Allogeneic hematopoietic cell transplantation (HCT) is associated with significant morbidity and mortality especially in the first year after HCT. In this...
RISK INDEX | COMPLETE REMISSION | UNRELATED DONORS | INTERNATIONAL BLOOD | ACUTE MYELOID-LEUKEMIA | IMMUNOLOGY | VERSUS-HOST-DISEASE | TRANSPLANTATION | MULTIVARIABLE ANALYSIS | SORAFENIB MAINTENANCE | ONCOLOGY | LATE DEATHS | WORKING GROUP-REPORT | HEMATOLOGY | Hematologic Neoplasms - therapy | Recurrence | Hematologic Neoplasms - mortality | Humans | Middle Aged | Risk Factors | Survivors | Male | Treatment Outcome | Hematopoietic Stem Cell Transplantation - mortality | Infection - etiology | Transplantation, Homologous - mortality | Young Adult | Disease-Free Survival | Hematopoietic Stem Cell Transplantation - adverse effects | Adult | Female | Aged | Tissue Donors | Graft vs Host Disease - etiology | Databases, Factual | Transplantation, Homologous - adverse effects | Graft-versus-host reaction | Transplants & implants | Mortality | Sex | Health risks | Risk reduction | Transplantation | Risk analysis | Patients | Survival | Morbidity | Risk factors | Hemopoiesis | Immunosuppression | Direct reduced iron | Mud
RISK INDEX | COMPLETE REMISSION | UNRELATED DONORS | INTERNATIONAL BLOOD | ACUTE MYELOID-LEUKEMIA | IMMUNOLOGY | VERSUS-HOST-DISEASE | TRANSPLANTATION | MULTIVARIABLE ANALYSIS | SORAFENIB MAINTENANCE | ONCOLOGY | LATE DEATHS | WORKING GROUP-REPORT | HEMATOLOGY | Hematologic Neoplasms - therapy | Recurrence | Hematologic Neoplasms - mortality | Humans | Middle Aged | Risk Factors | Survivors | Male | Treatment Outcome | Hematopoietic Stem Cell Transplantation - mortality | Infection - etiology | Transplantation, Homologous - mortality | Young Adult | Disease-Free Survival | Hematopoietic Stem Cell Transplantation - adverse effects | Adult | Female | Aged | Tissue Donors | Graft vs Host Disease - etiology | Databases, Factual | Transplantation, Homologous - adverse effects | Graft-versus-host reaction | Transplants & implants | Mortality | Sex | Health risks | Risk reduction | Transplantation | Risk analysis | Patients | Survival | Morbidity | Risk factors | Hemopoiesis | Immunosuppression | Direct reduced iron | Mud
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 82 - 82
Abstract The fludarabine, high dose cytarabine and G_CSF with or without idarubicin combination regimen, referred to as FLAG+/-Ida, is commonly used as a...
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3368 - 3368
Abstract Haploidentical donor (HID) transplant with post-transplant cyclophosphamide (PTCy) is being increasingly utilized worldwide. Although the original...
Journal Article
Blood Reviews, ISSN 0268-960X, 2016, Volume 30, Issue 5, pp. 333 - 339
Abstract Extramedullary leukemia (EM AML), also known as myeloid sarcoma, is a rare manifestation of acute myelogenous leukemia and often accompanies bone...
Hematology, Oncology and Palliative Medicine | Myelogenous | Therapy | Leukemia | Extramedullary | Leukemia, Myeloid, Acute | Humans | Chemotherapy | Sarcoma | Stem cells | Bone marrow | Cytogenetics | Transplantation | Lymphomas | Cancer
Hematology, Oncology and Palliative Medicine | Myelogenous | Therapy | Leukemia | Extramedullary | Leukemia, Myeloid, Acute | Humans | Chemotherapy | Sarcoma | Stem cells | Bone marrow | Cytogenetics | Transplantation | Lymphomas | Cancer
Journal Article
Bone Marrow Transplantation, ISSN 0268-3369, 2018, Volume 54, Issue 8, pp. 1218 - 1226
Initial therapy of chronic GVHD (cGvHD) has not changed for over three decades, despite limited efficacy and long-term toxicity. We have previously shown in a...
LONG-TERM SURVIVORS | BONE-MARROW | THROMBOTIC THROMBOCYTOPENIC PURPURA | IMMUNOLOGY | VERSUS-HOST-DISEASE | CONSENSUS DEVELOPMENT PROJECT | TRANSPLANTATION | ANTI-CD20 MONOCLONAL-ANTIBODY | ONCOLOGY | CLINICAL-TRIALS | DEPLETING THERAPY | QUALITY-OF-LIFE | STEM-CELL TRANSPLANTATION | HEMATOLOGY | Corticoids | Graft-versus-host reaction | Therapy | Corticosteroids | Effectiveness | Toxicity | Feasibility studies | Rituximab | Safety
LONG-TERM SURVIVORS | BONE-MARROW | THROMBOTIC THROMBOCYTOPENIC PURPURA | IMMUNOLOGY | VERSUS-HOST-DISEASE | CONSENSUS DEVELOPMENT PROJECT | TRANSPLANTATION | ANTI-CD20 MONOCLONAL-ANTIBODY | ONCOLOGY | CLINICAL-TRIALS | DEPLETING THERAPY | QUALITY-OF-LIFE | STEM-CELL TRANSPLANTATION | HEMATOLOGY | Corticoids | Graft-versus-host reaction | Therapy | Corticosteroids | Effectiveness | Toxicity | Feasibility studies | Rituximab | Safety
Journal Article
Bone Marrow Transplantation, ISSN 0268-3369, 05/2018, Volume 53, Issue 5, pp. 521 - 534
Haploidentical donors are now increasingly considered for transplantation in the absence of HLA-matched donors or when an urgent transplant is needed....
STEM-CELLS | BONE-MARROW | CORD BLOOD | PERIPHERAL-BLOOD | PRIMARY GRAFT FAILURE | IMMUNOLOGY | VERSUS-HOST-DISEASE | TRANSPLANTATION | CROSS-MATCH | ONCOLOGY | HIGH-RISK | LEUKEMIA WORKING PARTY | HEMATOLOGY | T-CELLS | Humans | Isoantibodies - analysis | Hematopoietic Stem Cell Transplantation - adverse effects | Transplantation, Haploidentical - adverse effects | Bone Marrow Transplantation - adverse effects | HLA Antigens - immunology | Treatment Outcome | Graft Rejection - immunology | Tissue Donors | Viral antibodies | Usage | Analysis | Antibodies | Practice guidelines (Medicine) | Bone marrow | Transplantation | Research | Hematopoietic stem cells | Antigens | Cell survival | Transplants & implants | Progenitor cells | Blood | Hemopoiesis | Rejection | Isoimmunization | Offspring | Grafts | Histocompatibility antigen HLA | Females | Life Sciences
STEM-CELLS | BONE-MARROW | CORD BLOOD | PERIPHERAL-BLOOD | PRIMARY GRAFT FAILURE | IMMUNOLOGY | VERSUS-HOST-DISEASE | TRANSPLANTATION | CROSS-MATCH | ONCOLOGY | HIGH-RISK | LEUKEMIA WORKING PARTY | HEMATOLOGY | T-CELLS | Humans | Isoantibodies - analysis | Hematopoietic Stem Cell Transplantation - adverse effects | Transplantation, Haploidentical - adverse effects | Bone Marrow Transplantation - adverse effects | HLA Antigens - immunology | Treatment Outcome | Graft Rejection - immunology | Tissue Donors | Viral antibodies | Usage | Analysis | Antibodies | Practice guidelines (Medicine) | Bone marrow | Transplantation | Research | Hematopoietic stem cells | Antigens | Cell survival | Transplants & implants | Progenitor cells | Blood | Hemopoiesis | Rejection | Isoimmunization | Offspring | Grafts | Histocompatibility antigen HLA | Females | Life Sciences
Journal Article