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by Lee, Shermin and Ripke, S and Neale, B.M and Faraone, S.V and Purcell, S.M and Perlis, R.H and Mowry, B.J and Thapar, A and Goddard, M.E and Witte, J.S and Absher, D and Agartz, I and Akil, H and Amin, F and Aneassen, O.A and Anjorin, A and Anney, R and Anttila, V and Arking, D.E and Asherson, P and Azevedo, M.H and Backlund, L and Badner, J.A and Bailey, A.J and Banaschewski, T and Barchas, J.D and Barnes, M.R and Barrett, T.B and Bass, N and Battaglia, A and Bauer, M and Bayes, M and Bellivier, F and Bergen, S.E and Berrettini, W and Betancur, C and Bettecken, T and Biederman, J and Binder, E.B and Black, D.W and Blackwood, D.H and Bloss, C.S and Boehnke, M and Boomsma, D.I and Breen, G and Breuer, R and Bruggeman, R and Cormican, P and Buccola, N.G and Buitelaar, J.K and Bunney, W.E and Buxbaum, J.D and Byerley, W.F and Byrne, E.M and Caesar, S and Cahn, W and Cantor, R.M and Casas, M and Chakravarti, A and Chambert, K and Choudhury, K and Cichon, S and Cloninger, C.R and Collier, D.A and Cook, E.H and Coon, H and Cormand, B and Corvin, A and Coryell, W.H and Craig, D.W and Craig, I.W and Crosbie, J and Cuccaro, M.L and Curtis, D and Czamara, D and Datta, S and Dawson, G and Day, R and Geus, E.J. de and Degenhardt, F and Djurovic, S and Donohoe, G.J and Doyle, A.E and Duan, J and Dudbridge, F and Duketis, E and Ebstein, R.P and Edenberg, H.J and Elia, J and Ennis, S and Etain, B and Fanous, A and Farmer, A.E and Ferrier, I.N and Flickinger, M and Fombonne, E and Foroud, T and Frank, J and Franke, B and et al and Cross-Disorder Grp Psychiat Genomi and Int Inflammatory Bowel Dis Genetic and Cross-Disorder Group of the Psychiatric Genomics Consortium
Nature Genetics, ISSN 1061-4036, 2013, Volume 45, Issue 9, pp. 984 - 994
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across... 
ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | CROHNS-DISEASE | DEFICIT HYPERACTIVITY DISORDER | COMMON SNPS | GENETICS & HEREDITY | SCHIZOPHRENIA | RISK | AUTISM SPECTRUM DISORDERS | BIPOLAR DISORDER | ASSOCIATION | HERITABILITY | Usage | Genetic aspects | Research | Single nucleotide polymorphisms | Psychoses | Genomics | Life Sciences | Biochemistry, Molecular Biology
Journal Article
by O'Dushlaine, Colm and Rossin, Lizzy and Lee, Phil H and Duncan, Laramie and Parikshak, Neelroop N and Newhouse, Stephen and Ripke, Stephan and Neale, Benjamin M and Purcell, Shaun M and Posthuma, Danielle and Nurnberger, John I and Lee, S. Hong and Faraone, Stephen V and Perlis, Roy H and Mowry, Bryan J and Thapar, Anita and Goddard, Michael E and Witte, John S and Absher, Devin and Agartz, Ingrid and Akil, Huda and Amin, Farooq and Aneassen, Ole A and Anjorin, Adebayo and Anney, Richard and Anttila, Verneri and Arking, Dan E and Asherson, Philip and Azevedo, Maria H and Backlund, Lena and Badner, Judith A and Bailey, Anthony J and Banaschewski, Tobias and Barchas, Jack D and Barnes, Michael R and Barrett, Thomas B and Bass, Nicholas and Battaglia, Agatino and Bauer, Michael and Bayés, Mònica and Bellivier, Frank and Bergen, Sarah E and Berrettini, Wade and Betancur, Catalina and Bettecken, Thomas and Biederman, Joseph and Binder, Elisabeth B and Black, Donald W and de Haan, Lieuwe and Linszen, Don H and Network & Pathway Anal Subgrp Psyc and IIBDGC and Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium and The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Nature neuroscience, ISSN 1097-6256, 2015, Volume 18, Issue 2, pp. 199 - 209
Journal Article
by Kunkle, BW and Grenier-Boley, B and Sims, R and Bis, JC and Damotte, V and Naj, AC and Boland, A and Vronskaya, M and van der Lee, SJ and Amlie-Wolf, A and Bellenguez, C and Frizatti, A and Chouraki, V and Martin, ER and Sleegers, K and Badarinarayan, N and Jakobsdottir, J and Hamilton-Nelson, KL and Moreno-Grau, S and Olaso, R and Raybould, R and Chen, YN and Kuzma, AB and Hiltunen, M and Morgan, T and Ahmad, S and Vardarajan, BN and Epelbaum, J and Hoffmann, P and Boada, M and Beecham, GW and Garnier, JG and Harold, D and Fitzpatrick, AL and Valladares, O and Moutet, ML and Gerrish, A and Smith, AV and Qu, LM and Bacq, D and Denning, N and Jian, XQ and Zhao, Y and Del Zompo, M and Fox, NC and Choi, SH and Mateo, I and Hughes, JT and Adams, HH and Malamon, J and Sanchez-Garcia, F and Patel, Y and Brody, JA and Dombroski, BA and Naranjo, MCD and Daniilidou, M and Eiriksdottir, G and Mukherjee, S and Wallon, D and Uphill, J and Aspelund, T and Cantwell, LB and Garzia, F and Galimberti, D and Hofer, E and Butkiewicz, M and Fin, B and Scarpini, E and Sarnowski, C and Bush, WS and Meslage, S and Kornhuber, J and White, CC and Song, Y and Barber, RC and Engelborghs, S and Sordon, S and Voijnovic, D and Adams, PM and Vandenberghe, R and Mayhaus, M and Cupples, LA and Albert, MS and De Deyn, PP and Gu, W and Himali, JJ and Beekly, D and Squassina, A and Hartmann, AM and Orellana, A and Blacker, D and Rodriguez-Rodriguez, E and Lovestone, S and Garcia, ME and Doody, RS and Munoz-Fernadez, C and Sussams, R and Lin, HH and Fairchild, TJ and Benito, YA and ... and Cohorts Heart Aging Res Genomic Ep and Alzheimer Dis Genetics Consortium and European Alzheimers Dis Initiative and Genetic Environm Risk AD Defining and Alzheimer Disease Genetics Consortium (ADGC) and Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) and European Alzheimer’s Disease Initiative (EADI) and Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES) and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
NATURE GENETICS, ISSN 1061-4036, 03/2019, Volume 51, Issue 3, pp. 414 - 414
Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially driven by genetics. To identify LOAD risk loci, we performed a large... 
COMMON VARIANTS | GENOTYPE IMPUTATION | AMYLOID-BETA | GENETICS & HEREDITY | DOMAIN-CONTAINING OXIDOREDUCTASE | MUTATIONS | ANGIOTENSIN-CONVERTING ENZYME | TRANSCRIPTION FACTOR | ONSET | GENOME-WIDE ASSOCIATION | APOLIPOPROTEIN-E | Genetic Predisposition to Disease - genetics | Lipids - genetics | Humans | Genetic Loci - genetics | Male | Genetic Testing - methods | Case-Control Studies | Haplotypes - genetics | tau Proteins - genetics | Amyloid beta-Peptides - genetics | Female | Lipid Metabolism - genetics | Aged | Alzheimer Disease - genetics | Genome-Wide Association Study - methods | Immunity - genetics | Ontology | Genomics | Genes | Lipids | Genomes | Mapping | Family medical history | Immunity | Risk factors | Protein turnover | Datasets | Proteins | Consortia | Genetic analysis | Dementia disorders | Genetics | Lipid metabolism | Alzheimer's disease | Age | ADAMTS-1 protein | Neurodegenerative diseases | Health risks | Metabolism | Risk analysis | Amyloid precursor protein | Meta-analysis | White blood cells | Genetic variance | Tau protein | Histocompatibility antigen HLA | Gene loci | Gene mapping | Alzheimers disease | Secretase | Dementia | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Plos Genetics, ISSN 1553-7404, 2011, Volume 7, Issue 3, pp. e1001324 - e1001324
Journal Article
Nature Genetics, ISSN 1061-4036, 05/2019, Volume 51, Issue 5, pp. 793 - 803
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of... 
Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis | Humans | Male | Genetic Loci | Systems Biology | Case-Control Studies | Journal Article | Depressive Disorder, Major/genetics | Bipolar Disorder/classification | Research Support, N.I.H., Intramural | Research Support, Non-U.S. Gov't | Psychotic Disorders/genetics | Female | Genetics | Polymorphism, Single Nucleotide | Schizophrenia/genetics | INDIVIDUALS | GWAS | METAANALYSIS | VARIANTS | GENES | GENETICS & HEREDITY | SCHIZOPHRENIA | RISK | LD SCORE REGRESSION | HERITABILITY | POLYGENICITY | Bipolar Disorder - genetics | Bipolar Disorder - classification | Psychotic Disorders - genetics | Schizophrenia - genetics | Depressive Disorder, Major - genetics | Quantitative trait loci | Genome-wide association studies | Usage | Bipolar disorder | Genetic aspects | Identification and classification | Health aspects | Risk factors | Neurosciences | Genealogy | Working groups | Mental disorders | Secretion | Genomics | Neurobiology | Schizophrenia | Genomes | Mental depression | Gene expression | Insulin | Loci | Datasets | Psychosis | Studies | Consortia | Heterogeneity | Cannabinoids | Liability | Genetic analysis | Ion channels | Alzheimers disease | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Ruderfer, Douglas M and Ripke, Stephan and McQuillin, Andrew and Boocock, James and Stahl, Eli A and Pavlides, Jennifer M. Whitehead and Mullins, Niamh and Charney, Alexander W and Ori, Anil P.S and Loohuis, Loes M. Olde and Domenici, Enrico and Di Florio, Arianna and Papiol, Sergi and Kalman, Janos L and Trubetskoy, Vassily and Adolfsson, Rolf and Agartz, Ingrid and Agerbo, Esben and Akil, Huda and Albani, Diego and Albus, Margot and Alda, Martin and Alexander, Madeline and Alliey-Rodriguez, Ney and Als, Thomas D and Amin, Farooq and Anjorin, Adebayo and Arranz, Maria J and Awasthi, Swapnil and Bacanu, Silviu A and Badner, Judith A and Baekvad-Hansen, Marie and Bakker, Steven and Band, Gavin and Barchas, Jack D and Barroso, Ines and Bass, Nicholas and Bauer, Michael and Baune, Bernhard T and Begemann, Martin and Bellenguez, Celine and Belliveau, Richard A and Bellivier, Frank and Bender, Stephan and Bene, Judit and Bergen, Sarah E and Berrettini, Wade H and Bevilacqua, Elizabeth and Biernacka, Joanna M and Bigdeli, Tim B and Black, Donald W and Blackburn, Hannah and Blackwell, Jenefer M and Blackwood, Douglas H.R and Pedersen, Carsten Bocker and Boehnke, Michael and Boks, Marco and Borglum, Anders D and Bramon, Elvira and Breen, Gerome and Brown, Matthew A and Bruggeman, Richard and Buccola, Nancy G and Buckner, Randy L and Budde, Monika and Bulik-Sullivan, Brendan and Bumpstead, Suzannah J and Bunney, William and Burmeister, Margit and Buxbaum, Joseph D and Bybjerg-Grauholm, Jonas and Byerley, William and Cahn, Wiepke and Cai, Guiqing and Cairns, Murray J and Campion, Dominique and Cantor, Rita M and Carr, Vaughan J and Carrera, Noa and Casas, Juan P and Casas, Miquel and Catts, Stanley V and Cervantes, Pablo and Chambert, Kimberley D and Chan, Raymond C.K and Chen, Eric Y.H and Chen, Ronald Y.L and Cheng, Wei and Cheung, Eric F.C and Chong, Siow Ann and Clarke, Toni-Kim and Cloninger, C. Robert and Cohen, David and Cohen, Nadine and Coleman, Jonathan R.I and Collier, David A and Cormican, Paul and Coryell, William and Craddock, Nicholas and Craig, David W and ... and Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium and Wellcome Trust Case-Control Consortium and Psychosis Endophenotypes International Consortium and Psychosis Endophenotypes Inter and Psychiat Genomics Consortium and Wellcome Trust Case-Control and Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address: douglas.ruderfer@vanderbilt.edu
Cell, ISSN 0092-8674, 06/2018, Volume 173, Issue 7, pp. 1705 - 1715.e16
Journal Article