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Cell (Cambridge), ISSN 0092-8674, 04/2020, Volume 181, Issue 2, pp. 211 - 211
Tazemetostat is the first epigenetic therapy to gain FDA approval in a solid tumor. This lysine methyltransferase inhibitor targets EZH2, the enzymatic subunit... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Antimitotic agents | Enzymes | Epigenetic inheritance | Medical colleges | Care and treatment | Sarcoma | Lysine | Antineoplastic agents | Drug approval | Index Medicus
Journal Article
Nature clinical practice. Oncology, ISSN 1743-4254, 12/2005, Volume 2, Issue 1, pp. S4 - S11
Journal Article
Journal Article
by Brat, Daniel J and Verhaak, Roel G. W and Aldape, Kenneth D and Yung, W. K. Alfred and Salama, Sofie R and Cooper, Lee A. D and Rheinbay, Esther and Miller, C. Ryan and Vitucci, Mark and Morozova, Olena and Robertson, A. Gordon and Noushmehr, Houtan and Laird, Peter W and Cherniack, Andrew D and Akbani, Rehan and Huse, Jason T and Ciriello, Giovanni and Poisson, Laila M and Barnholtz-Sloan, Jill S and Berger, Mitchel S and Brennan, Cameron and Colen, Rivka R and Colman, Howard and Flanders, Adam E and Giannini, Caterina and Grifford, Mia and Iavarone, Antonio and Jain, Rajan and Joseph, Isaac and Kim, Jaegil and Kasaian, Katayoon and Mikkelsen, Tom and Murray, Bradley A and O'Neill, Brian Patrick and Pachter, Lior and Parsons, Donald W and Sougnez, Carrie and Sulman, Erik P and Vandenberg, Scott R and Van Meir, Erwin G and Von Deimling, Andreas and Zhang, Hailei and Crain, Daniel and Lau, Kevin and Mallery, David and Morris, Scott and Paulauskis, Joseph and Penny, Robert and Shelton, Troy and Sherman, Mark and Yena, Peggy and Black, Aaron and Bowen, Jay and Dicostanzo, Katie and Gastier-Foster, Julie and Leraas, Kristen M and Lichtenberg, Tara M and Pierson, Christopher R and Ramirez, Nilsa C and Taylor, Cynthia and Weaver, Stephanie and Wise, Lisa and Zmuda, Erik and Davidsen, Tanja and Demchok, John A and Eley, Greg and Ferguson, Martin L and Hutter, Carolyn M and Shaw, Kenna R. Mills and Ozenberger, Bradley A and Sheth, Margi and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean Claude and Ayala, Brenda and Baboud, Julien and Chudamani, Sudha and Jensen, Mark A and Liu, Jia and Pihl, Todd and Raman, Rohini and Wan, Yunhu and Wu, Ye and Ally, Adrian and Auman, J. Todd and Balasundaram, Miruna and Balu, Saianand and Baylin, Stephen B and Beroukhim, Rameen and Bootwalla, Moiz S and Bowlby, Reanne and Bristow, Christopher A and Brooks, Denise and Butterfield, Yaron and Carlsen, Rebecca and Carter, Scott and Chin, Lynda and Chu, Andy and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
The New England journal of medicine, ISSN 1533-4406, 06/2015, Volume 372, Issue 26, pp. 2481 - 2498
Journal Article
by Kim, Jihun and Bowlby, Reanne and Mungall, Andrew J and Robertson, A. Gordon and Odze, Robert D and Cherniack, Andrew D and Shih, Juliann and Pedamallu, Chandra Sekhar and Cibulskis, Carrie and Dunford, Andrew and Meier, Samuel R and Kim, Jaegil and Raphael, J and Wu, Hsin-Ta and Wong, Alexandra M and Willis, Joseph E and Bass, Adam J and Derks, Sarah and Garman, Katherine and McCall, Shannon J and Wiznerowicz, MacIej and Pantazi, Angeliki and Parfenov, Michael and Thorsson, Vésteinn and Shmulevich, Ilya and Dhankani, Varsha and Miller, Michael and Sakai, Ku Leuven Ryo and Wang, Kenneth and Schultz, Nikolaus and Shen, Ronglai and Arora, Arshi and Weinhold, Nils and Sánchez-Vega, Francisco and Kelsen, David P and Zhang, Julia and Felau, Ina and Demchok, John and Rabkin, Charles S and Camargo, M. Constanza and Zenklusen, Jean Claude and Bowen, Jay and Leraas, Kristen and Lichtenberg, Tara M and Curtis, Christina and Seoane, Jose A and Ojesina, Akinyemi I and Beer, David G and Gulley, Margaret L and Pennathur, Arjun and Luketich, James D and Zhou, Zhongren and Weisenberger, Daniel J and Akbani, Rehan and Lee, Ju-Seog and Liu, Wenbin and Mills, Gordon B and Zhang, Wei and Reid, Brian J and Hinoue, Toshinori and Laird, Peter W and Shen, Hui and Piazuelo, M. Blanca and Schneider, Barbara G and McLellan, Michael and Taylor-Weiner, Amaro and Lawrence, Michael and Cibulskis, Kristian and Stewart, Chip and Getz, Gad and Lander, Eric and Gabriel, Stacey B and DIng, Li and McLellan, Michael D and Miller, Christopher A and Appelbaum, Elizabeth L and Cordes, Matthew G and Fronick, Catrina C and Fulton, Lucinda A and Mardis, Elaine R and Wilson, Richard K and Schmidt, Heather K and Fulton, Robert S and Ally, Adrian and Balasundaram, Miruna and Carlsen, Rebecca and Chuah, Eric and Dhalla, Noreen and Holt, Robert A and Jones, Steven J. M and Kasaian, Katayoon and Brooks, Denise and Li, Haiyan I and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Karen L and Schein, Jacqueline E and Sipahimalani, Payal and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Data Coordination Center: CSRA Inc and Duke University and Ribeirão Preto Medical School and Israelitisches Krankenhaus Hamburg and Project Team: National Institutes of Health and Tissue Source Sites: Analytic Biologic Services and Nationwide Children’s Hospital and Greater Poland Cancer Centre and Brown University and University of Michigan and Mayo Clinic and Broad Institute and Keimyung University School of Medicine and Asan Medical Center and Barretos Cancer Hospital and University of Alabama and Indiana University School of Medicine and Invidumed and National Cancer Center Goyang and Yonsei University College of Medicine and Vanderbilt University and University of North Carolina at Chapel Hill and Cureline and Cancer Genome Atlas Research Network and Institute of Oncology of Moldova and University of Pittsburgh School of Medicine and University of Pittsburgh and Genome Characterization Centers: BC Cancer Agency and Analysis Working Group: Asan University and University of Texas MD Anderson Cancer Center and Case Western Reserve University and National Cancer Institute and Genome Data Analysis Centers: Broad Institute and St. Joseph’s Hospital &Medical Center and University of Southern California and Institute for Systems Biology and Ontario Tumour Bank and University of Washington and University of Rochester and Harvard Medical School and KU Leuven and Genome Sequencing Center: Broad Institute and Brigham and Women’s Hospital and Memorial Sloan Kettering Cancer Center and Disease Working Group: Duke University and Erasmus University and Christiana Care Health System and University of Kansas Medical Center and Research Institute at Nationwide Children’s Hospital and International Genomics Consortium and Tayside Tissue Bank and Peter MacCallum Cancer Centre and Pusan National University Medical School and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University and BioreclamationIVT and Dana-Farber Cancer Institute and University of Southern California Epigenome Center and Stanford University and BC Cancer Agency and Chonnam National University Medical School and St. Petersburg Academic University and University of North Carolina and University of Dundee and Van Andel Research Institute and Washington University in St. Louis and Emory University and Washington University and University of California Santa Cruz and Biospecimen Core Resource: International Genomics Consortium and Asterand Bioscience and Botkin Municipal Clinic
Nature (London), ISSN 1476-4687, 01/2017, Volume 541, Issue 7636, pp. 169 - 175
Journal Article