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Cell Cycle, ISSN 1538-4101, 10/2012, Volume 11, Issue 19, pp. 3559 - 3567
Journal Article
Immunity, ISSN 1074-7613, 11/2005, Volume 23, Issue 5, pp. 479 - 490
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2010, Volume 285, Issue 12, pp. 9172 - 9179
Wnt/β-catenin signaling is initiated at the cell surface by association of secreted Wnt with its receptors Frizzled (Fz) and low density lipoprotein... 
Dickkopf (Dkk1) | Signal Transduction | Molecular Biophysics | Biochemistry | Biophysics | Cell Surface Receptor | Wnt Pathway | Lipoprotein-like Receptor (LRP) | Protein-Protein Interactions
Journal Article
Science, ISSN 0036-8075, 10/2009, Volume 326, Issue 5952, pp. 572 - 574
The Hedgehog (Hh) signaling pathway is inappropriately activated in certain human cancers, including medulloblastoma, an aggressive brain tumor. GDC-0449, a... 
Receptors | Relapse | Basal cell carcinoma | Medulloblastoma | Amino acids | Biopsies | Reports | Genetic mutation | Tumors | Resistance mechanisms | Cancer | PROTEIN-COUPLED RECEPTORS | CYCLOPAMINE | CANCER | MULTIDISCIPLINARY SCIENCES | Anilides - therapeutic use | Receptors, G-Protein-Coupled - metabolism | Humans | Brain Neoplasms - pathology | Hedgehog Proteins - metabolism | Molecular Sequence Data | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Mutation, Missense | Antineoplastic Agents - metabolism | Neoplasm Metastasis | Hedgehog Proteins - genetics | Medulloblastoma - pathology | Smoothened Receptor | Veratrum Alkaloids - pharmacology | Antineoplastic Agents - pharmacology | Patched Receptors | Medulloblastoma - genetics | Mutant Proteins - antagonists & inhibitors | Pyridines - therapeutic use | Amino Acid Sequence | Signal Transduction | Anilides - metabolism | Brain Neoplasms - genetics | Receptors, Cell Surface - metabolism | Mutant Proteins - metabolism | Hedgehog Proteins - antagonists & inhibitors | Brain Neoplasms - drug therapy | Cinnamates - pharmacology | Animals | Pyridines - metabolism | Mutant Proteins - chemistry | Anilides - pharmacology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Cell Line, Tumor | Protein Conformation | Mice | Pyridines - pharmacology | Receptors, G-Protein-Coupled - genetics | Medulloblastoma - drug therapy | Receptors, G-Protein-Coupled - chemistry | Amino Acid Substitution | Receptors, Cell Surface - genetics | Gene mutations | Development and progression | Genetic aspects | Diagnosis | Drug resistance | Identification and classification | Signal transduction | Genotype & phenotype | Inhibitor drugs | Cellular biology | Brain cancer | Mutation | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 2011, Volume 145, Issue 4, pp. 513 - 528
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2012, Volume 109, Issue 1, pp. 273 - 278
Toll like receptors (TLRs) use Toll—IL-1 receptor (TIR) domain-containing adapters, such as myeloid differentiation primary response gene 88 (MyD88) and TIR... 
T lymphocytes | Myeloid cells | Phosphorylation | B lymphocytes | Cell lines | Toll like receptors | Ligands | Inflammation | Gene expression regulation | Macrophages | Innate immunity | Negative regulator | Macrophage | Pattern recognition receptors | ACTIVATION | HOMEOSTASIS | MULTIDISCIPLINARY SCIENCES | macrophage | TRANSDUCTION | PHOSPHOINOSITIDE 3-KINASE | pattern recognition receptors | negative regulator | innate immunity | inflammation | PATHWAY | DROSOPHILA TOLL | PATTERN-RECOGNITION RECEPTORS | Adaptor Proteins, Signal Transducing - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Inflammation - pathology | B-Lymphocytes - enzymology | Macrophages - pathology | Membrane Glycoproteins - metabolism | Signal Transduction | Humans | Mice, Inbred C57BL | Molecular Sequence Data | Phosphatidylinositol 3-Kinases - metabolism | Mice, Knockout | Inflammation - metabolism | Macrophages - metabolism | Animals | HEK293 Cells | Mice | Enzyme Activation | Toll-Like Receptors - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Myeloid Differentiation Factor 88 - metabolism | Genetic aspects | Cellular signal transduction | B cells | Research | Properties | Human immunogenetics | Protein kinases | Proteins | Signal transduction | Kinases | Gene expression | Cells | Index Medicus | Transcription factors | Cytokines | Serine | AKT protein | Homology | MAP kinase | 1-Phosphatidylinositol 3-kinase | Infection | NF- Kappa B protein | Molecular modelling | beta -Interferon | Lymphocytes B | Dextran sulfate | MyD88 protein | Toll-like receptors | Interferon | Protein-serine/threonine kinase | Colitis | Differentiation | Biological Sciences
Journal Article
Structure, ISSN 0969-2126, 04/2012, Volume 20, Issue 4, pp. 676 - 687
Journal Article