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Neurology, ISSN 0028-3878, 02/2019, Volume 92, Issue 8, pp. 355 - 356
Cerebral white matter hyperintensities (WMH), abnormal areas of signal intensity on MRI, occur predominantly in the periventricular and deep white matter and... 
AFRICAN | SMALL-VESSEL DISEASE | BRAIN | CLINICAL NEUROLOGY | GENOME-WIDE ASSOCIATION
Journal Article
Genes, ISSN 2073-4425, 11/2019, Volume 10, Issue 11, p. 903
While approximately 200 autosomal genetic associations outside of the major histocompatibility complex (MHC) have been identified for multiple sclerosis (MS)... 
Journal Article
by Beecham, Ashley H and Patsopoulos, Nikolaos A and Xifara, Dionysia K and Davis, Mary F and Kemppinen, Anu and Cotsapas, Chris and Shah, Tejas S and Spencer, Chris and Booth, David and Goris, An and Oturai, Annette and Saarela, Janna and Fontaine, Bertrand and Hemmer, Bernhard and Martin, Claes and Zipp, Frauke and D'Alfonso, Sandra and Martinelli-Boneschi, Filippo and Taylor, Bruce and Harbo, Hanne F and Kockum, Ingrid and Hillert, Jan and Olsson, Tomas and Ban, Maria and Oksenberg, Jorge R and Hintzen, Rogier and Barcellos, Lisa F and Agliardi, Cristina and Alfredsson, Lars and Alizadeh, Mehdi and Anderson, Carl and Andrews, Robert and Søndergaard, Helle Bach and Baker, Amie and Band, Gavin and Baranzini, Sergio E and Barizzone, Nadia and Barrett, Jeffrey and Bellenguez, Céline and Bergamaschi, Laura and Bernardinelli, Luisa and Berthele, Achim and Biberacher, Viola and Binder, Thomas M.C and Blackburn, Hannah and Bomfim, Izaura L and Brambilla, Paola and Broadley, Simon and Brochet, Bruno and Brundin, Lou and Buck, Dorothea and Butzkueven, Helmut and Caillier, Stacy J and Camu, William and Carpentier, Wassila and Cavalla, Paola and Celius, Elisabeth G and Coman, Irène and Comi, Giancarlo and Corrado, Lucia and Cosemans, Leentje and Cournu-Rebeix, Isabelle and Cree, Bruce A.C and Cusi, Daniele and Damotte, Vincent and Defer, Gilles and Delgado, Silvia R and Deloukas, Panos and Di Sapio, Alessia and Dilthey, Alexander T and Donnelly, Peter and Dubois, Bénédicte and Duddy, Martin and Edkins, Sarah and Elovaara, Irina and Esposito, Federica and Evangelou, Nikos and Fiddes, Barnaby and Field, Judith and Franke, Andre and Freeman, Colin and Frohlich, Irene Y and Galimberti, Daniela and Gieger, Christian and Gourraud, Pierre-Antoine and Graetz, Christiane and Graham, Andrew and Grummel, Verena and Guaschino, Clara and Hadjixenofontos, Athena and Hakonarson, Hakon and Halfpenny, Christopher and Hall, Gillian and Hall, Per and Hamsten, Anders and Harley, James and Harrower, Timothy and Hawkins, Clive and Hellenthal, Garrett and Hillier, Charles and ... and Wellcome Trust Case Control Consor and Int IBD Genetics Consortium IIBDGC and International Multiple Sclerosis Genetics Consortium (IMSGC) and Wellcome Trust Case Control Consortium 2 (WTCCC2) and International IBD Genetics Consortium (IIBDGC) and Institutionen för fysik, kemi och biologi and Linköpings universitet and Bioinformatik and Tekniska högskolan
Nature Genetics, ISSN 1061-4036, 2013, Volume 45, Issue 11, pp. 1353 - 1362
Journal Article
by Adams, H.H and Hibar, D.P and Chouraki, V and Stein, J.L and Nyquist, P.A and Renteria, M.E and Trompet, S and Arias-Vasquez, A and Seshai, S and Desrivieres, S and Beecham, A.H and Jahanshad, N and Wittfeld, K and Lee, S.J. van der and Abramovic, L and Alhusaini, S and Amin, N and Andersson, M and Arfanakis, K and Aribisala, B.S and Armstrong, N.J and Athanasiu, L and Axelsson, T and Beiser, A and Bernard, M and Bis, J.C and Blanken, L.M and Blanton, S.H and Bohlken, M.M and Boks, M.P and Bralten, J and Brickman, A.M and Carmichael, O and Chakravarty, M.M and Chauhan, G and Chen, Q and Ching, C.R and Cuellar-Partida, G and Braber, A.D and Doan, N.T and Ehrlich, S and Filippi, I and Ge, T and Giddaluru, S and Goldman, A.L and Gottesman, R.F and Greven, C.U and Grimm, O and Griswold, M.E and Guadalupe, T.M and Hass, J and Haukvik, U.K and Hilal, S and Hofer, E and Hoehn, D and Holmes, A.J and Hoogman, M and Janowitz, D and Jia, T and Kasperaviciute, D and Kim, S and Klein, M and Kraemer, B and Lee, P.H and Liao, J and Liewald, D.C and Lopez, L.M and Luciano, M and Macare, C and Marquand, A and Matarin, M and Mather, K.A and Mattheisen, M and Mazoyer, B and McKay, D.R and McWhirter, R and Milaneschi, Y and Mirza-Schreiber, N and Muetzel, R.L and Maniega, S.M and Nho, K and Nugent, A.C and Loohuis, L.M and Oosterlaan, J and Papmeyer, M and Pappa, I and Pirpamer, L and Pudas, S and Putz, B and Rajan, K.B and Ramasamy, A and Richards, J.S and Risacher, S.L and Roiz-Santianez, R and Rommelse, N and Rose, E.J and Royle, N.A and Rundek, T and Samann, P.G and Satizabal, C.L and ... and EPIGEN and SYS and Alzheimer's Dis Neuroimaging Initi and IMAGEN and Mind Research Network, Albuquerque, NM (United States) and Medicinska fakulteten and Institutionen för integrativ medicinsk biologi (IMB) and Umeå centrum för funktionell hjärnavbildning (UFBI) and Umeå universitet
Nature Neuroscience, ISSN 1097-6256, 2016, Volume 19, Issue 12, pp. 1569 - 1582
Journal Article
by Hibar, Derrek P and Adams, Hieab H. H and Jahanshad, Neda and Chauhan, Ganesh and Stein, Jason L and Hofer, Edith and Renteria, Miguel E and Bis, Joshua C and Arias-Vasquez, Alejano and Ikram, M. Kamran and Desrivières, Sylvane and Vernooij, Meike W and Abramovic, Lucija and Alhusaini, Saud and Amin, Najaf and Andersson, Micael and Arfanakis, Konstantinos and Aribisala, Benjamin S and Armstrong, Nicola J and Athanasiu, Lavinia and Axelsson, Tomas and Beecham, Ashley H and Beiser, Alexa and Bernard, Manon and Blanton, Susan H and Bohlken, Marc M and Boks, Marco P and Bralten, Janita and Brickman, Adam M and Carmichael, Owen and Chakravarty, M. Mallar and Chen, Qiang and Ching, Christopher R. K and Chouraki, Vincent and Cuellar-Partida, Gabriel and Crivello, Fabrice and den Braber, Anouk and Doan, Nhat Trung and Ehrlich, Stefan and Giddaluru, Sudheer and Goldman, Aaron L and Gottesman, Rebecca F and Grimm, Oliver and Griswold, Michael E and Guadalupe, Tulio and Gutman, Boris A and Hass, Johanna and Haukvik, Unn K and Hoehn, David and Holmes, Avram J and Hoogman, Martine and Janowitz, Deborah and Jia, Tianye and Jørgensen, Kjetil N and Karbalai, Nazanin and Kasperaviciute, Dalia and Kim, Sungeun and Klein, Marieke and Kraemer, Bernd and Lee, Phil H and Liewald, David C. M and Lopez, Lorna M and Luciano, Michelle and Macare, Christine and Marquand, Ane F and Matarin, Mar and Mather, Karen A and Mattheisen, Manuel and McKay, David R and Milaneschi, Yuri and Muñoz Maniega, Susana and Nho, Kwangsik and Nugent, Allison C and Nyquist, Paul and Loohuis, Loes M. Olde and Oosterlaan, Jaap and Papmeyer, Martina and Pirpamer, Lukas and Pütz, Benno and Ramasamy, Adaikalavan and Richards, Jennifer S and Risacher, Shannon L and Roiz-Santiañez, Roberto and Rommelse, Nanda and Ropele, Stefan and Rose, Emma J and Royle, Natalie A and Rundek, Tatjana and Sämann, Philipp G and Saremi, Arvin and Satizabal, Claudia L and Schmaal, Lianne and Schork, Anew J and Shen, Li and Shin, Jean and Shumskaya, Elena and Smith, Albert V and Sprooten, Emma and Strike, Lachlan T and Teumer, Alexander and ... and Medicinska fakulteten and Institutionen för integrativ medicinsk biologi (IMB) and Umeå centrum för funktionell hjärnavbildning (UFBI) and Umeå universitet
Nature communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, p. 13624
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2015, Volume 47, Issue 10, pp. 1107 - 1113
Journal Article
Journal Article
by Verhaaren, Benjamin F.J and Debette, Stéphanie and Bis, Joshua C and Smith, Jennifer A and Ikram, M Kamran and Adams, Hieab H and Beecham, Ashley H and Rajan, Kumar B and Lopez, Lorna M and Barral, Sandra and van Buchem, Mark A and van der Grond, Jeroen and Smith, Albert V and Hegenscheid, Katrin and Aggarwal, Neelum T and de Andrade, Mariza and Atkinson, Elizabeth J and Beekman, Marian and Beiser, Alexa S and Blanton, Susan H and Boerwinkle, Eric and Brickman, Adam M and Bryan, R Nick and Chauhan, Ganesh and Chen, Christopher P.L.H and Chouraki, Vincent and de Craen, Anton J.M and Crivello, Fabrice and Deary, Ian J and Deelen, Joris and De Jager, Philip L and Dufouil, Carole and Elkind, Mitchell S.V and Evans, Denis A and Freudenberger, Paul and Gottesman, Rebecca F and Gunason, Vilmundur and Habes, Mohamad and Heckbert, Susan R and Heiss, Gerardo and Hilal, Saima and Hofer, Edith and Hofman, Albert and Ibrahim-Verbaas, Carla A and Knopman, David S and Lewis, Cora E and Liao, Jiemin and Liewald, David C.M and Luciano, Michelle and van der Lugt, Aad and Martinez, Oliver O and Mayeux, Richard and Mazoyer, Bernard and Nalls, Mike and Nauck, Matthias and Niessen, Wiro J and Oostra, Ben A and Psaty, Bruce M and Rice, Kenneth M and Rotter, Jerome I and von Sarnowski, Bettina and Schmidt, Helena and Schreiner, Pamela J and Schuur, Maaike and Sidney, Stephen S and Sigurdsson, Sigurdur and Slagboom, P Eline and Stott, David J.M and van Swieten, John C and Teumer, Alexander and Töglhofer, Anna Maria and Traylor, Matthew and Trompet, Stella and Turner, Stephen T and Tzourio, Christophe and Uh, Hae-Won and Uitterlinden, André G and Vernooij, Meike W and Wang, Jing J and Wong, Tien Y and Wardlaw, Joanna M and Windham, B Gwen and Wittfeld, Katharina and Wolf, Christiane and Wright, Clinton B and Yang, Qiong and Zhao, Wei and Zijdenbos, Alex and Jukema, J Wouter and Sacco, Ralph L and Kardia, Sharon L.R and Amouyel, Philippe and Mosley, Thomas H and Longstreth, W T and DeCarli, Charles C and van Duijn, Cornelia M and Schmidt, Reinhold and Launer, Lenore J and Grabe, Hans J and Seshadri, Sudha S and ...
Circulation: Cardiovascular Genetics, ISSN 1942-325X, 04/2015, Volume 8, Issue 2, pp. 398 - 409
Journal Article
by Patsopoulos, NA and Baranzini, SE and Santaniello, A and Shoostari, P and Cotsapas, C and Wong, G and Beecham, AH and James, T and Replogle, J and Vlachos, IS and McCabe, C and Pers, TH and Brandes, A and White, C and Keenan, B and Cimpean, M and Winn, P and Panteliadis, IP and Robbins, A and Andlauer, TFM and Zarzycki, O and Dubois, B and Goris, A and Sondergaard, HB and Sellebjerg, F and Sorensen, PS and Ullum, H and Thorner, LW and Saarela, J and Cournu-Rebeix, I and Damotte, V and Fontaine, B and Guillot-Noel, L and Lathrop, M and Vukusic, S and Berthele, A and Pongratz, V and Gasperi, C and Graetz, C and Grummel, V and Hemmer, B and Hoshi, M and Knier, B and Korn, T and Lill, CM and Luessi, F and Muhlau, M and Zipp, F and Dardiotis, E and Agliardi, C and Amoroso, A and Barizzone, N and Benedetti, MD and Bernardinelli, L and Cavalla, P and Clarelli, F and Comi, G and Cusi, D and Esposito, F and Ferre, L and Galimberti, D and Guaschino, C and Leone, MA and Martinelli, V and Moiola, L and Salvetti, M and Sorosina, M and Vecchio, D and Zauli, A and Santoro, S and Mancini, N and Zuccala, M and Mescheriakova, J and van Duijn, C and Bos, SD and Celius, EG and Spurkland, A and Comabella, M and Montalban, X and Alfredsson, L and Bomfim, IL and Gomez-Cabrero, D and Hillert, J and Jagodic, M and Linden, M and Piehl, F and Jelcic, I and Martin, R and Sospedra, M and Baker, A and Ban, M and Hawkins, C and Hysi, P and Kalra, S and Karpe, F and Khadake, J and Lachance, G and Molyneux, P and Neville, M and Thorpe, J and ... and Australia New Zealand IBDGC and Int Multiple Sclerosis Genetics Co and Initiative Crohn Colitis and Belgium Genetic Consortiumt and United Kingdom IBDGC and ANZgene and WTCCC2 and IIBDGC and NIDDK IBDGCJ and Wellcome Trust Case Control Conso and International Multiple Sclerosis Genetics Consortium and Örebro universitet and Institutionen för medicinska vetenskaper
SCIENCE, ISSN 0036-8075, 09/2019, Volume 365, Issue 6460, pp. 1417 - 1417
Journal Article
by Mitrovič, Mitja and Patsopoulos, Nikolaos A and Beecham, Ashley H and Dankowski, Theresa and Goris, An and Dubois, Bénédicte and D’hooghe, Marie B and Lemmens, Robin and Van Damme, Philip and Søndergaard, Helle Bach and Sellebjerg, Finn and Sorensen, Per Soelberg and Ullum, Henrik and Thørner, Lise W and Werge, Thomas and Saarela, Janna and Cournu-Rebeix, Isabelle and Damotte, Vincent and Fontaine, Bertrand and Guillot-Noel, Lena and Lathrop, Mark and Vukusik, Sandra and Gourraud, Pierre-Antoine and Andlauer, Till F.M and Pongratz, Viola and Buck, Dorothea and Gasperi, Christiane and Bayas, Antonios and Heesen, Christoph and Kümpfel, Tania and Linker, Ralf and Paul, Friedemann and Stangel, Martin and Tackenberg, Björn and Bergh, Florian Then and Warnke, Clemens and Wiendl, Heinz and Wildemann, Brigitte and Zettl, Uwe and Ziemann, Ulf and Tumani, Hayrettin and Gold, Ralf and Grummel, Verena and Hemmer, Bernhard and Knier, Benjamin and Lill, Christina M and Luessi, Felix and Dardiotis, Efthimios and Agliardi, Cristina and Barizzone, Nadia and Mascia, Elisabetta and Bernardinelli, Luisa and Comi, Giancarlo and Comi, Cristoforo and Cusi, Daniele and Esposito, Federica and Ferrè, Laura and Galimberti, Daniela and Leone, Maurizio A and Sorosina, Melissa and Mescheriakova, Julia and Hintzen, Rogier and van Duijn, Cornelia and Theunissen, Charlotte E and Bos, Steffan D and Myhr, Kjell-Morten and Celius, Elisabeth G and Lie, Benedicte A and Spurkland, Anne and Comabella, Manuel and Montalban, Xavier and Alfredsson, Lars and Stridh, Pernilla and Hillert, Jan and Jagodic, Maja and Piehl, Fredrik and Jelčić, Ilijas and Martin, Roland and Sospedra, Mireia and Ban, Maria and Hawkins, Clive and Hysi, Pirro and Kalra, Seema and Karpe, Fredrik and Khadake, Jyoti and Lachance, Genevieve and Neville, Matthew and Santaniello, Adam and Caillier, Stacy J and Calabresi, Peter A and Cree, Bruce A.C and Cross, Anne and Davis, Mary F and Haines, Jonathan L and de Bakker, Paul I.W and Delgado, Silvia and Dembele, Marieme and Edwards, Keith and Fitzgerald, Kathryn C and Hakonarson, Hakon and ... and Int Multiple Sclerosis Genetics and International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu and International Multiple Sclerosis Genetics Consortium
Cell, ISSN 0092-8674, 11/2018, Volume 175, Issue 6, pp. 1679 - 1687.e7
Multiple sclerosis is a complex neurological disease, with ∼20% of risk heritability attributable to common genetic variants, including >230 identified by... 
POPULATION | METAANALYSIS | REPLICATION | VARIANTS | GENETIC RISK | BIOCHEMISTRY & MOLECULAR BIOLOGY | LINKAGE | GENOME-WIDE ASSOCIATION |