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1. Critical Discourse Analysis of the Protesters' Language
by Begum, Gulnaz
Language in India, ISSN 1930-2940, 03/2015, Volume 15, Issue 3, pp. 85 - 95
The current study is conducted for presenting a critical discourse analysis of the mob's language that assembled to record protest against gas and electricity... 
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2. Full Text Warfarin thromboprophylaxis in cancer patients with central venous catheters (WARP): an open-label randomised trial
by Young, Annie M, PGCSR and Billingham, Lucinda J, PhD and Begum, Gulnaz, BSc and Kerr, David J, Prof and Hughes, Ana I, BSc and Rea, Daniel W, PhD and Shepherd, Stephen, MD and Stanley, Andrew, MPhil and Sweeney, Ann, MSc and Wilde, Jonathan, MD and Wheatley, Keith, Prof and WARP Collaborat Grp UK and WARP Collaborative Group, UK
Lancet, The, ISSN 0140-6736, 2009, Volume 373, Issue 9663, pp. 567 - 574
Summary Background The role and dose of anticoagulants in thromboprophylaxis for patients with cancer receiving chemotherapy through central venous catheters... 
Internal Medicine | PROPHYLAXIS | MEDICINE, GENERAL & INTERNAL | RISK-FACTORS | CENTRAL VEIN CATHETER | THROMBOSIS | MOLECULAR-WEIGHT HEPARIN | DOUBLE-BLIND | PREVENTION | COMPLICATIONS | THROMBOEMBOLISM | Meta-Analysis as Topic | Humans | Middle Aged | Neoplasms - mortality | Warfarin - adverse effects | Anticoagulants - therapeutic use | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Anticoagulants - adverse effects | Venous Thrombosis - etiology | Neoplasms - drug therapy | Warfarin - therapeutic use | International Normalized Ratio | Female | Venous Thrombosis - prevention & control | Aged | Hemorrhage - chemically induced | Catheterization, Central Venous - adverse effects | Prevention | Cancer patients | Care and treatment | Warfarin | Antibiotics | Central venous catheters | Dosage and administration | Health aspects | Thrombosis | Blood clot | Risk factors | Clinical trials | Medical research | Drug therapy | Catheters | Cancer | Index Medicus | Abridged Index Medicus
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3. Full Text Early Mortality After Diagnosis of Multiple Myeloma: Analysis of Patients Entered Onto the United Kingdom Medical Research Council Trials Between 1980 and 2002—Medical Research Council Adult Leukaemia Working Party
by Bradley M. Augustson and Gulnaz Begum and Janet A. Dunn and Nicola J. Barth and Faith Davies and Gareth Morgan and Judith Behrens and Alastair Smith and J. Anthony Child and Mark T. Drayson
Journal of Clinical Oncology, ISSN 0732-183X, 12/2005, Volume 23, Issue 36, pp. 9219 - 9226
Purpose: Early mortality in multiple myeloma (MM) is usually attributed to combined effects of active disease and comorbid factors. We have studied early... 
STAGING SYSTEM | SURVIVAL | PROGNOSTIC-FACTORS | ONCOLOGY | SEVERE RENAL-FAILURE | RANDOMIZED-TRIAL | GAMMA-GLOBULIN | RISK | INFECTION | STEM-CELL TRANSPLANT | CHEMOTHERAPY | Prognosis | Age Factors | Comorbidity | Multiple Myeloma - mortality | Humans | Middle Aged | Logistic Models | Male | Multiple Myeloma - pathology | Sensitivity and Specificity | Female | Renal Insufficiency - complications | Aged | Retrospective Studies | Neoplasm Staging | Infection - complications
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4. Full Text Glial Na+‐dependent ion transporters in pathophysiological conditions
by Boscia, Francesca and Begum, Gulnaz and Pignataro, Giuseppe and Sirabella, Rossana and Cuomo, Ornella and Casamassa, Antonella and Sun, Dandan and Annunziato, Lucio
Glia, ISSN 0894-1491, 10/2016, Volume 64, Issue 10, pp. 1677 - 1697
Sodium dynamics are essential for regulating functional processes in glial cells. Indeed, glial Na+ signaling influences and regulates important glial... 
Na+‐HCO3‐ cotransporter | Na+/Ca2+ exchanger | Na+/H+ exchanger | Na+‐K+‐Cl‐ cotransporter | Na+/K+ ATPase | oligodendrocytes | astrocytes | microglia | HCO | ATPase | exchanger | Cl | cotransporter | Ca | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | CATION-CHLORIDE COTRANSPORTERS | CULTURED RAT ASTROCYTES | FOCAL CEREBRAL-ISCHEMIA | EXCHANGER ISOFORM 1 | INTRACELLULAR PH REGULATION | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROSCIENCES | WHITE-MATTER INJURY | K+-CL-COTRANSPORTER | CENTRAL-NERVOUS-SYSTEM | Na+-HCO3- cotransporter | Na+-K+-Cl- cotransporter | Animals | Humans | Neuroglia - physiology | Membrane Transport Proteins - metabolism | Signal Transduction - physiology | Sodium - metabolism | Ion Transport - physiology | Nervous System Diseases - pathology | Nervous system diseases | Adenosine triphosphatase | Homeostasis | Alzheimers disease | Rodents | Na+-HCO3− cotransporter | K+ ATPase | H+ exchanger | Ca2+ exchanger | Na+ | Na+-K+-Cl− cotransporter
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5. Full Text DHA inhibits ER Ca2+ release and ER stress in astrocytes following in vitro ischemia
by Begum, Gulnaz and Kintner, Douglas and Liu, Yan and Cramer, Samuel W and Sun, Dandan
Journal of Neurochemistry, ISSN 0022-3042, 02/2012, Volume 120, Issue 4, pp. 622 - 630
J. Neurochem. (2012) 120, 622–630. Docosahexaenoic acid (DHA) has neuroprotective effects in several neurodegenerative disease conditions. However, the... 
ER Ca2 | ER stress | ryanodine receptor | IP3 receptor | polyunsaturated fatty acid | CELLS | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | FATTY-ACIDS | ARACHIDONIC-ACID | RELEASE | NEUROSCIENCES | UNFOLDED PROTEIN RESPONSE | K+-CL-COTRANSPORTER | DOCOSAHEXAENOIC ACID | ENDOPLASMIC-RETICULUM | BRAIN | Astrocytes - drug effects | Cell Hypoxia - drug effects | Cell Hypoxia - physiology | Endoplasmic Reticulum Stress - drug effects | Calcium - metabolism | Calcium Signaling - physiology | Astrocytes - pathology | Cells, Cultured | Ischemia - metabolism | Endoplasmic Reticulum - secretion | Calcium - antagonists & inhibitors | Docosahexaenoic Acids - pharmacology | Endoplasmic Reticulum - pathology | Animals | Neuroprotective Agents - pharmacology | Calcium Signaling - drug effects | Endoplasmic Reticulum - drug effects | Oxidation-Reduction - drug effects | Mice | Ischemia - pathology | Astrocytes - secretion | Endoplasmic Reticulum Stress - physiology | Neurochemistry | Oxidative stress | Signal transduction | Brain | Ischemia
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6. Full Text CSIG-01. NA-K-CL COTRANSPORTER PROTEIN IN THE PATHOGENESIS OF LOW-GRADE GLIOMAS
by Luo, Lanxin and Guan, Xiudong and Begum, Gulnaz and Ding, Dawei and Kohanbash, Gary and Sun, Baoshan and Sun, Dandan
Neuro-Oncology, ISSN 1522-8517, 11/2019, Volume 21, Issue Supplement_6, pp. vi44 - vi44
Abstract Low-grade gliomas (LGGs) present a high incidence of epilepsy, infiltrative growth, resistance to therapy, and high risk of transforming into... 
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7. Full Text Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter
by Kahle, Kristopher T and Flores, Bianca and Bharucha-Goebel, Diana and Zhang, Jinwei and Donkervoort, Sandra and Hegde, Madhuri and Hussain, Gulnaz and Duran, Daniel and Liang, Bo and Sun, Dandan and Bönnemann, Carsten G and Delpire, Eric
Science Signaling, ISSN 1945-0877, 08/2016, Volume 9, Issue 439, pp. ra77 - ra77
Using exome sequencing, we identified a de novo mutation (c.2971A>G; T991A) in SLC12A6, the gene encoding the K+-Cl(-)cotransporter KCC3, in a patient with an... 
HEREDITARY MOTOR | CATION-CHLORIDE COTRANSPORTERS | K+-CL-COTRANSPORTER | BIOCHEMISTRY & MOLECULAR BIOLOGY | CORPUS-CALLOSUM | DISEASE | ANDERMANN-SYNDROME | CONDITIONAL MOUSE MODEL | MICE | CELL-VOLUME HOMEOSTASIS | MISSENSE MUTATIONS | CELL BIOLOGY | WNK Lysine-Deficient Protein Kinase 1 - metabolism | Humans | Peripheral Nervous System Diseases - enzymology | Male | Motor Neurons - enzymology | Mutation, Missense | Motor Neurons - pathology | Symporters - metabolism | Phosphorylation - genetics | Animals | Mice, Mutant Strains | Symporters - genetics | HEK293 Cells | Female | Mice | Peripheral Nervous System Diseases - pathology | Peripheral Nervous System Diseases - genetics | WNK Lysine-Deficient Protein Kinase 1 - genetics
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8. Full Text Selective knockout of astrocytic Na+/H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke
by Begum, Gulnaz and Song, Shanshan and Wang, Shaoxia and Zhao, Hanshu and Bhuiyan, Mohammad Iqbal H and Li, Eric and Nepomuceno, Rachel and Ye, Qing and Sun, Ming and Calderon, Michael Joseph and Stolz, Donna B and St. Croix, Claudette and Watkins, Simon C and Chen, Yinhuai and He, Pingnian and Shull, Gary E and Sun, Dandan
Glia, ISSN 0894-1491, 01/2018, Volume 66, Issue 1, pp. 126 - 144
Stimulation of Na+/H+ exchanger isoform 1 (NHE1) in astrocytes causes ionic dysregulation under ischemic conditions. In this study, we created a Nhe1flox/flox... 
MMP | blood–brain barrier | gliosis | cerebral edema | astrocyte end‐feet | neurovascular unit | astrocyte end-feet | blood-brain barrier | NEUROSCIENCES | Glial Fibrillary Acidic Protein - genetics | Cerebrovascular Circulation - physiology | Male | Cerebrovascular Circulation - genetics | Glial Fibrillary Acidic Protein - metabolism | Blood-Brain Barrier - ultrastructure | Gliosis - pathology | Matrix Metalloproteinase 9 - metabolism | Reperfusion | Infarction, Middle Cerebral Artery - complications | Gliosis - etiology | Disease Models, Animal | Microscopy, Electron, Transmission | Gliosis - genetics | Brain Infarction - diagnosis | Gene Expression Regulation - genetics | Gliosis - metabolism | Mice, Inbred C57BL | Sodium-Hydrogen Exchanger 1 - genetics | Mice, Transgenic | Infarction, Middle Cerebral Artery - pathology | Astrocytes - ultrastructure | Blood-Brain Barrier - pathology | Brain Infarction - etiology | Motor Activity - genetics | Sodium-Hydrogen Exchanger 1 - deficiency | Animals | Neurologic Examination | Mice | Brain Infarction - genetics | Astrocytes - metabolism | Stroke (Disease) | Brain damage | Ischemia | Cytochemistry | Proteases | Analysis | Occlusion | Matrix metalloproteinases | Hydrogen | Recombinase | Gene deletion | Corn oil | Clonal deletion | Blood-brain barrier | Nhe1 gene | Cerebral blood flow | Rodents | Deletion | Cerebral infarction | Edema | Stroke | Tight junctions | Astrocytes | Na+/H+-exchanging ATPase | Inflammation | Tamoxifen | Ablation | Endothelial cells | Flox | Gelatinase B | Blood flow | Neurological diseases | Injury prevention | Gliosis | Infarction | Brain injury | Hypertrophy
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9. Full Text Selective role of Na+/H+ exchanger in Cx3cr1+ microglial activation, white matter demyelination, and post‐stroke function recovery
by Song, Shanshan and Wang, Shaoxia and Pigott, Victoria M and Jiang, Tong and Foley, Lesley M and Mishra, Abhishek and Nayak, Rachana and Zhu, Wen and Begum, Gulnaz and Shi, Yejie and Carney, Karen E and Hitchens, T. Kevin and Shull, Gary E and Sun, Dandan
Glia, ISSN 0894-1491, 11/2018, Volume 66, Issue 11, pp. 2279 - 2298
Na+/H+ exchanger (NHE1) activation is required for multiple microglial functions. We investigated effects of selective deletion of microglial Nhe1 in... 
phagocytosis | macrophages | inflammation | microglia | white matter tissue repair | SURVIVAL | BRAIN-INJURY | FOCAL CEREBRAL-ISCHEMIA | RECEPTOR | CNS | NEUROSCIENCES | NEURONAL DEATH | GROWTH | MICE | EXPRESSION | Microglia - metabolism | Somatosensory Disorders - etiology | Brain - diagnostic imaging | Recovery of Function - drug effects | Male | CX3C Chemokine Receptor 1 - metabolism | CX3C Chemokine Receptor 1 - genetics | Infarction, Middle Cerebral Artery - complications | Recovery of Function - physiology | Female | Demyelinating Diseases - etiology | Infarction, Middle Cerebral Artery - drug therapy | Microfilament Proteins - metabolism | Infarction, Middle Cerebral Artery - diagnostic imaging | Demyelinating Diseases - drug therapy | Disease Models, Animal | Calcium-Binding Proteins - metabolism | Macrophages - pathology | Microglia - drug effects | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Sodium-Hydrogen Exchanger 1 - genetics | Mice, Transgenic | Nerve Tissue Proteins - genetics | White Matter - pathology | Brain - drug effects | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Macrophages - metabolism | White Matter - diagnostic imaging | Animals | Tamoxifen - pharmacology | Sodium-Hydrogen Exchanger 1 - metabolism | Mice | Stroke (Disease) | Neurons | Analysis | Brain damage | Bone morphogenetic proteins | Inflammation | Macrophages | Transforming growth factors | Brain | CD86 antigen | Hydrogen | CX3CR1 protein | Activation | Recovery | Proteins | Cell activation | Corn oil | Clonal deletion | Ischemia | Demyelination | Rodents | Animal tissues | Deletion | Lesions | Repair | Stroke | CD11b antigen | Cell survival | Therapeutic applications | Astrocytes | Na+/H+-exchanging ATPase | Glial fibrillary acidic protein | Tamoxifen | Substantia alba | Survival | Microglia | Myelination | Brain injury | Ca2+/calmodulin-dependent protein kinase II
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10. Full Text Allogeneic Stem-Cell Transplantation Using a Reduced-Intensity Conditioning Regimen Has the Capacity to Produce Durable Remissions and Long-Term Disease-Free Survival in Patients With High-Risk Acute Myeloid Leukemia and Myelodysplasia
by Sudhir Tauro and Charles Craddock and Karl Peggs and Gulnaz Begum and Premini Mahendra and Gordon Cook and Judith Marsh and Donald Milligan and Anthony Goldstone and Ann Hunter and Asim Khwaja and Raj Chopra and Timothy Littlewood and Andrew Peniket and Anne Parker and Graham Jackson and Geoff Hale and Mark Cook and Nigel Russell and Stephen Mackinnon
Journal of Clinical Oncology, ISSN 0732-183X, 12/2005, Volume 23, Issue 36, pp. 9387 - 9393
Purpose The toxicity of allogeneic stem-cell transplantation can be substantially reduced using a reduced-intensity conditioning (RIC) regimen. This has... 
AML | SOUTHWEST-ONCOLOGY-GROUP | ONCOLOGY | IMMUNOTHERAPY | BONE-MARROW-TRANSPLANTATION | IN-VIVO | MALIGNANCIES | 1ST COMPLETE REMISSION | VERSUS-HOST-DISEASE | FLUDARABINE | BUSULFAN | Recurrence | Acute Disease | Humans | Middle Aged | Risk Factors | Male | Treatment Outcome | Vidarabine - analogs & derivatives | Transplantation, Homologous | Graft vs Host Disease | Leukemia, Myeloid - pathology | Stem Cell Transplantation | Disease-Free Survival | Leukemia, Myeloid - drug therapy | Melphalan - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Survival Analysis | Adult | Female | Aged | Vidarabine - administration & dosage | Myelodysplastic Syndromes - pathology | Myelodysplastic Syndromes - drug therapy
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11. Full Text Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas
by Guan, XD and Luo, LX and Begum, G and Kohanbash, G and Song, QK and Rao, A and Amankulor, N and Sun, BS and Sun, DD and Jia, W
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, ISSN 1756-9966, 10/2018, Volume 37, Issue 1, pp. 255 - 16
BackgroundSodium/hydrogen exchanger 1 (NHE1), encoded by the SLC9A1 gene (SoLute Carrier family 9A1) in humans, is the main H+ efflux mechanism in maintaining... 
MIGRATION | NHE1 | IDH MUTATION | TUMOR | macrophage | NHE1 inhibitor HOE642 | CELL-PROLIFERATION | Anti-PD1 therapy | IMMUNE | Angiogenesis | Immunosuppression | ONCOLOGY | Tumor-associated microglia | GASTRIC-CANCER | UP-REGULATION | EXPRESSION | PROGRESSION | Neoplasm Transplantation | Up-Regulation | Prognosis | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Guanidines - pharmacology | Male | Gene Expression Profiling | Sulfones - pharmacology | Brain Neoplasms - metabolism | Glioma - metabolism | Glioma - genetics | Neoplasm Grading | Glioma - pathology | Female | Guanidines - administration & dosage | Cell Survival - drug effects | Mice, Inbred C57BL | Brain Neoplasms - genetics | Sodium-Hydrogen Exchanger 1 - genetics | Brain Neoplasms - drug therapy | Animals | Sequence Analysis, RNA | Survival Analysis | Cell Line, Tumor | Sodium-Hydrogen Exchanger 1 - metabolism | Cell Proliferation - drug effects | Mice | Glioma - drug therapy | Sulfones - administration & dosage | Glycolysis | Research | Gliomas | Carcinogenesis | Cancer cells | Dehydrogenases | Brain cancer | Genomes | Cancer therapies | Datasets | Studies | Proteins | Survival analysis | Medical prognosis | Hypoxia | Tumorigenesis | Bioinformatics | Tumors | Tumor-associated microglia/macrophage
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