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Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 04/2018, Volume 365, Issue 1, pp. 202 - 211
It has recently been demonstrated that pharmacological blockade of the glycine transporter 1 (GlyT1) reduced alcohol intake and relapse in rats. The aim of the... 
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 09/2017, Volume 334, pp. 105 - 108
Amphetamine and methylphenidate are known to have stimulatory effect in healthy subjects but not in humans with attention deficit hyperactivity disorder and in... 
Dopamine transporter | Tyrosine hydroxylase | Amphetamine | Paradoxical calming effect | SYSTEM | ADHD | PHOSPHORYLATION | HYPERACTIVITY | MECHANISMS | NEUROSCIENCES | ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | GENE | INCREASE | BEHAVIORAL SCIENCES | MICE | BINDING | Tyrosine | Analysis | Attention-deficit hyperactivity disorder | Phenols | Hydroxylases | Central nervous system agents | Neurophysiology
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2018, Volume 61, Issue 17, pp. 7486 - 7502
The development of glycine transporter 1 (GlyT1) inhibitors may offer putative treatments for schizophrenia and other disorders associated with hypofunction of... 
CHEMISTRY, MEDICINAL | ANTAGONIST | MICROSOMES | SCHIZOPHRENIA | CANDIDATES | GLYT1 | BINDING | BRAIN | L-687,414 | P-GLYCOPROTEIN | KETAMINE
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2018, Volume 61, Issue 17, pp. 7503 - 7524
The glycine transporter 1 (GlyT1) has emerged as a key novel target for the treatment of schizophrenia. Herein, we report the synthesis and biological... 
INTERNALIZATION | CHEMISTRY, MEDICINAL | ANTAGONIST | HYDROGENATION | PHARMACOLOGY | SCHIZOPHRENIA | CNS | OPTIMIZATION | D-ASPARTATE RECEPTOR | BRAIN | P-GLYCOPROTEIN
Journal Article
F1000Research, ISSN 2046-1402, 2016, Volume 5
Extensive evidence on rapid and long-lasting antidepressant effects of intravenous ketamine motivated efforts to identify underlying mechanisms that would... 
Cell Signaling | Data Sharing | Pharmacokinetics & Drug Delivery | Neuropharmacology & Psychopharmacology
Journal Article
2012, 2012, Handbook of Experimental Pharmacology, ISBN 9783642257575, Volume 213, Issue 213
Book Chapter
F1000Research, ISSN 2046-1402, 2016, Volume 5, p. 634
Extensive evidence on rapid and long-lasting antidepressant effects of intravenous ketamine motivated efforts to identify underlying mechanisms that would... 
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 09/2007, Volume 26, Issue 5, pp. 1079 - 1090
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 09/2007, Volume 26, Issue 5, pp. 1079 - 1090
Journal Article
Journal of Pharmacological and Toxicological Methods, ISSN 1056-8719, 07/2011, Volume 64, Issue 1, pp. e52 - e52
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2010, Volume 6, Issue 4, pp. S540 - S540
Journal Article
Journal Article
03/2016
Compounds of formula (I) are disclosed Compounds of formula (I) are useful in treating conditions and disorders prevented by or ameliorated by PDE10A ligands.... 
HYGIENE | METALLURGY | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | APPARATUS THEREFOR | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HETEROCYCLIC COMPOUNDS | HUMAN NECESSITIES | GENERAL METHODS OF ORGANIC CHEMISTRY
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