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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2015, Volume 112, Issue 4, pp. 1125 - 1130
Graft-versus-host disease (GvHD) is a life-threatening immunological complication after allogenic hematopoietic stem cell transplantation (allo-HCT). The... 
Graft-versus-host disease | Graft-versus-leukemia effect | Hematopoietic stem cell transplantation | Regulatory T cell | NFAT | TRANSCRIPTION FACTORS | INTERLEUKIN-2 | BONE-MARROW-TRANSPLANTATION | IMMUNE RECONSTITUTION | MULTIDISCIPLINARY SCIENCES | regulatory T cell | VERSUS-HOST-DISEASE | REGULATORY CELLS | IN-VIVO | hematopoietic stem cell transplantation | CALCINEURIN | LEUKEMIA | graft-versus-host disease | graft-versus-leukemia effect | LYMPHOCYTES | Calcineurin Inhibitors - pharmacology | Cell Proliferation - genetics | CD8-Positive T-Lymphocytes - pathology | Cyclosporine - pharmacology | Hematopoietic Stem Cell Transplantation | Graft vs Host Disease - immunology | T-Lymphocytes, Regulatory - pathology | Graft vs Host Disease - pathology | Mice, Knockout | T-Lymphocytes, Regulatory - immunology | Graft vs Host Disease - genetics | Allografts | Animals | NFATC Transcription Factors - immunology | Tacrolimus - pharmacology | Graft vs Leukemia Effect - immunology | Cell Proliferation - drug effects | Mice | CD8-Positive T-Lymphocytes - immunology | Graft vs Leukemia Effect - genetics | Disease Models, Animal | NFATC Transcription Factors - genetics | Cell interaction | Leukemia | Physiological aspects | Graft versus host reaction | T cells | Observations | Health aspects | Hematopoietic stem cells | Biological Sciences
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 08/2019, Volume 10
An intricate network of molecular and cellular actors orchestrates the delicate balance between effector immune responses and immune tolerance. The pleiotropic... 
RHEUMATOID-ARTHRITIS | FACTOR TNF RECEPTORS | DOWN-REGULATION | GVHD | C-REL | INFLAMMATORY ARTHRITIS | TNFR2 agonists | IMMUNOLOGY | VERSUS-HOST-DISEASE | FACTOR-ALPHA | CUTTING EDGE | LIGAND ASSEMBLY DOMAIN | graft vs. host disease | AUTOIMMUNE-DISEASES | Tregs (regulatory T cells) | TNFR family costimulatory receptors | cancer | TNFR2 antagonism
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155087
Multiple myeloma is one of the most common hematological diseases and is characterized by an aberrant proliferation of plasma cells within the bone marrow. As... 
METASTASIS SUPPRESSOR | CANCER-CELLS | SYSTEM | MAINTENANCE | PROTEIN | GPR54 | KISSPEPTIN-10 | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | SECRETION | CELL-LINES | Multiple Myeloma - pathology | Animals | Receptors, G-Protein-Coupled - metabolism | Coculture Techniques | Humans | Cells, Cultured | Biomarkers, Tumor - metabolism | Tumor Microenvironment | Mice | Multiple Myeloma - metabolism | Receptors, Kisspeptin-1 | Mesenchymal Stem Cells - metabolism | Complications and side effects | Usage | Care and treatment | Prognosis | Multiple myeloma | Diagnostic imaging | Biological markers | Cell culture | G protein-coupled receptors | Target recognition | Crosstalk | Fluorescent indicators | Metastasis | Osteolysis | Proteins | Bone marrow | Biocompatibility | Physiology | Bioindicators | Immunoglobulins | Internal medicine | Interdisciplinary aspects | Bone turnover | Metabolism | Gene expression | Hospitals | Light chains | Stem cells | Biomarkers | Kiss1 protein | Aberration | Bone imaging | Endocrinology | Cell proliferation | Osteoprogenitor cells | Mesenchyme | Laboratories | Homeostasis | Fluorescence | Stem cell transplantation | Joint surgery | Bone diseases | Kinases | Hematological diseases | Biomedical materials | Rodents | Lesions | Pharmaceutical sciences | Urine | Medical imaging | Bone lesions | Hematology | Tumor cells | Medicine | Bone cancer | Microscopy | Plasma cells | In vivo methods and tests | Diagnostic systems | Bone | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e81320
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2016, Volume 138, Issue 5, pp. 1256 - 1268
Adoptive transfer of donor‐derived cytolytic T‐lymphocytes (CTL) has evolved as a promising strategy to improve graft‐versus‐leukemia (GvL) effects in... 
Allogeneic hematopoietic stem cell transplantation | adoptive T‐cell therapy | CD45RA‐derived cytolytic T lymphocytes | patient‐individualized immunotherapy | acute myeloid leukemia | donor‐patient specific humanized mouse model | CD45RA-derived cytolytic T lymphocytes | patient-individualized immunotherapy | adoptive T-cell therapy | donor-patient specific humanized mouse model | STEM-CELLS | RELAPSED LEUKEMIA | TUMOR-REGRESSION | ACUTE MYELOID-LEUKEMIA | LYMPHOCYTIC-LEUKEMIA | ALLOGENEIC BONE-MARROW | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | IN-VIVO | ANTITUMOR IMMUNITY | NAIVE PRECURSORS | Neoplasm, Residual | T-Lymphocytes, Cytotoxic - immunology | Animals | Graft vs Leukemia Effect | Immunotherapy, Adoptive | Histocompatibility Testing | Humans | HLA-B Antigens - immunology | Mice | Leukemia, Myeloid, Acute - immunology | Leukemia, Myeloid, Acute - therapy | Precision Medicine | Squamous cell carcinoma | Histocompatibility antigens | Analysis | Leukemia | Immunotherapy | HLA histocompatibility antigens | Transplantation | T cells | Hematopoietic stem cells | Bone marrow | Antigens | Transplants & implants | Lymphocytes | Cell culture | Therapy | Syngeneic grafts | CD8 antigen | CD45RA antigen | Medical services | Stem cell transplantation | Cytotoxicity | Stimulation | Lymphocytes T | In vitro testing | Immunity | Grafting | Adoptive transfer | Anticancer properties | Allografts | Spleen | Memory cells | Effectiveness | Myeloid leukemia | Immunodeficiency | Minimal residual disease | Durability | T cell receptors | Regression analysis | Interleukin 15 | Patients | Survival | Hemopoiesis | Graft rejection | Rejection | Antitumor activity | Infiltration | Histocompatibility antigen HLA | Acute myeloid leukemia
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e52398
Background: Multiple myeloma (MM) is a B-cell malignancy, where malignant plasma cells clonally expand in the bone marrow of older people, causing significant... 
MIGRATION | CLEARANCE | MARROW | CHEMOKINES | MULTIDISCIPLINARY SCIENCES | GROWTH | PLASMACYTOMA | MICE | PROTEINS | MELPHALAN | T-CELLS | Neoplasm Invasiveness | Humans | Bone Marrow Cells - pathology | Molecular Imaging - methods | Treatment Outcome | Melphalan - therapeutic use | Disease Progression | Hematopoiesis - drug effects | Luciferases - genetics | Cell Movement - drug effects | Multiple Myeloma - drug therapy | Multiple Myeloma - pathology | Animals | Cell Line, Tumor | Bone Marrow Cells - drug effects | Female | Spatio-Temporal Analysis | Cell Proliferation - drug effects | Melphalan - pharmacology | Mice | Mice, Inbred BALB C | Multiple Myeloma - genetics | Disease Models, Animal | Anemia | Luciferase | Multiple myeloma | Aged | Diagnostic imaging | Metastasis | Health aspects | Tropism | Drugs | Therapy | Plasma | Flow cytometry | Bioluminescence | Animal models | Tracking | Calcium | Medical services | Malignancy | Drug development | Experiments | Cancer therapies | Immunosuppressive agents | Metastases | Homing | Renal insufficiency | Calcium (blood) | Histopathology | CD44 antigen | Animal tissues | Melphalan | Bone marrow | Life sciences | Lesions | Monitoring | Enzyme-linked immunosorbent assay | Immunoglobulins | Kidneys | Bone lesions | Mortality | Histology | Morbidity | CXCR4 protein | Medicine | Serum levels | Cytometry | Lymphocytes B | Plasma cells | Genetic engineering | Bone | Elderly | Cell migration | Kidney transplantation
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 07/2015, Volume 126, Issue 4, pp. 437 - 444
Inhibition of the tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK)/fibroblast growth factor-inducible 14 (Fn14) system reduces intestinal... 
WEAK INDUCER | EPITHELIAL-CELLS | BONE-MARROW-TRANSPLANTATION | IN-VIVO | TNF-ALPHA | TWEAK/FN14 INTERACTION | HEMATOLOGY | VERSUS-HOST-DISEASE | ANTITUMOR ACTIVITIES | GAMMA RECEPTOR ENGAGEMENT | TUMOR ACTIVITY | Humans | Male | Intestines - metabolism | Graft vs Host Disease - metabolism | Luminescent Measurements | TWEAK Receptor | Intestines - immunology | Receptors, IgG - metabolism | Immunoglobulin G - immunology | Receptors, Tumor Necrosis Factor - antagonists & inhibitors | Hematopoietic Stem Cell Transplantation - adverse effects | Female | Graft vs Host Disease - etiology | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Receptors, Tumor Necrosis Factor - genetics | Receptors, Tumor Necrosis Factor - metabolism | Intestines - pathology | Antibody-Dependent Cell Cytotoxicity | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Tumor Necrosis Factors - metabolism | Rituximab | Receptors, IgG - immunology | Reverse Transcriptase Polymerase Chain Reaction | Tumor Necrosis Factors - immunology | Immunoglobulin G - administration & dosage | Blotting, Western | Graft vs Host Disease - pathology | Tumor Necrosis Factor-alpha - pharmacology | Cytokine TWEAK | Animals | Fluorescent Antibody Technique | Graft vs Host Disease - prevention & control | Mice | Mice, Inbred BALB C | Receptors, Tumor Necrosis Factor - immunology | Antibodies, Monoclonal, Murine-Derived - therapeutic use | Apoptosis | Tumor Necrosis Factors - antagonists & inhibitors | Plenary Paper
Journal Article
Blood, ISSN 0006-4971, 06/2010, Volume 115, Issue 23, pp. 4628 - 4630
Journal Article
Journal Article