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Nature, ISSN 0028-0836, 12/2010, Volume 468, Issue 7327, pp. 1119 - 1123
Interaction of pathogens with cells of the immune system results in activation of inflammatory gene expression. This response, although vital for immune... 
MACHINES | BINDING MODULES | CHROMATIN | MULTIDISCIPLINARY SCIENCES | COMPLEXES | GENE-EXPRESSION | BROMODOMAIN PROTEIN BRD4 | TRANSCRIPTIONAL ELONGATION | P-TEFB | Sepsis - prevention & control | Salmonella Infections - immunology | Shock, Septic - prevention & control | Salmonella Infections - physiopathology | Salmonella typhimurium | Heterocyclic Compounds, 4 or More Rings - pharmacology | Sepsis - drug therapy | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Inflammation - drug therapy | Shock, Septic - drug therapy | Anti-Inflammatory Agents - therapeutic use | Hydroxamic Acids - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Protein Structure, Tertiary | Salmonella Infections - drug therapy | Genome-Wide Association Study | Epigenomics | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Heterocyclic Compounds, 4 or More Rings - chemistry | Kaplan-Meier Estimate | Models, Molecular | Salmonella Infections - prevention & control | Benzodiazepines | Gene Expression Regulation - drug effects | Acetylation - drug effects | Animals | Anti-Inflammatory Agents - chemistry | Lipopolysaccharides - pharmacology | Histone Deacetylase Inhibitors - pharmacology | Macrophages - drug effects | Inflammation - prevention & control | Mice | Proteins | Pathology | Eukaryotes | Chromatin | Immunology | Pharmacology | Gene expression | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 10/2011, Volume 478, Issue 7370, pp. 529 - 533
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2017, Volume 68, Issue 3, pp. 566 - 580.e10
The PI3K signaling pathway regulates cell growth and movement and is heavily mutated in cancer. Class I PI3Ks synthesize the lipid messenger PI(3,4,5)P .... 
INPP4B | PI(3,4)P2 | invadopodia | PI3K | SHIP2 | PTEN | prostate | cancer | PI(3,4,5)P3 | PI(3,4,5)P | PI(3,4)P | Index Medicus
Journal Article
MOLECULAR CELL, ISSN 1097-2765, 11/2017, Volume 68, Issue 3, pp. 566 - 566
Journal Article
EMBO MOLECULAR MEDICINE, ISSN 1757-4676, 09/2016, Volume 8, Issue 9, pp. 1099 - 1112
Influenza A virus (IAV)-induced severe disease is characterized by infected lung epithelia, robust inflammatory responses and acute lung injury. Since type I... 
influenza | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNE-RESPONSE | infection | GENE PROTECTS MICE | INNATE | INDUCTION | interferon lambda | INTERFERON-ALPHA | immunopathology | RESISTANCE | interferon alpha | EXPRESSION | Interferon | Infections | Cytokines | Influenza
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2010, Volume 107, Issue 37, pp. 16234 - 16239
T-cell interactions with antigen-presenting cells are important for CD8 T-cell effector or memory fate determination. The integrin leukocyte... 
T lymphocytes | Antigens | Lymphocytes | Memory | Infections | Physiological regulation | Chemokines | T cell antigen receptors | Daughter cells | Integrins | Integrin | Lymphocytic choriomeningitis virus | Costimulation | Chemotaxis | ACTIVATION | memory | MULTIDISCIPLINARY SCIENCES | B-CELLS | costimulation | PYK2 | IMMUNE-RESPONSES | CO-STIMULATION | ANTIGENIC-STIMULATION | lymphocytic choriomeningitis virus | FOCAL ADHESION KINASE | integrin | chemotaxis | CD8-Positive T-Lymphocytes - cytology | Cell Survival | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation, Neoplastic | CD8-Positive T-Lymphocytes - enzymology | Lymphocyte Function-Associated Antigen-1 - immunology | Mice, Knockout | Cell Lineage | Animals | Focal Adhesion Kinase 2 - metabolism | Immunologic Memory | Receptors, Antigen, T-Cell - immunology | Cell Differentiation | Mice | Focal Adhesion Kinase 2 - deficiency | CD8-Positive T-Lymphocytes - immunology | Focal Adhesion Kinase 2 - immunology | Tyrosine | Research | T cells | Properties | Phosphotransferases | Leucocytes | T cell receptors | Kinases | Cell adhesion & migration | Index Medicus | Infection | Signal transduction | Immunological memory | Leukocyte migration | Antigen-presenting cells | CD8 antigen | Effector cells | Lymphocytes T | Protein-tyrosine kinase | double prime T-cell receptor | LFA-1 antigen | Biological Sciences
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2017, Volume 68, Issue 3, p. 566
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.molcel.2017.09.024 
Epidermal growth factor | Phosphatases | Prostate cancer | Analysis | Resveratrol | Medical colleges
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2004, Volume 382, Issue 2, pp. 393 - 409
Two members of the NF-kappaB (nuclear factor kappaB)/Rel transcription factor family, NF-kappaB1 and NF-kappaB2, are produced as precursor proteins, NF-kappaB1... 
IκB kinase (IKK) | p100 | Tumour progression locus-2 (TPL-2) | Nuclear factor κB (NF-κB) | p105 | Toll-like receptor (TLR) | nuclear factor kappa B (NF-kappa B) | TRCP UBIQUITIN LIGASE | I kappa B kinase (IKK) | BIOCHEMISTRY & MOLECULAR BIOLOGY | P105 REQUIRES PHOSPHORYLATION | ALLERGIC AIRWAY INFLAMMATION | KINASE KINASE KINASE | P50 SUBUNIT | GLYCINE-RICH REGION | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | tumour progression locus-2 (TPL-2) | NF-KAPPA-B | SIGNAL-TRANSDUCTION PATHWAY | TNF, tumour necrosis factor | GC, germinal centre | NEMO, nuclear factor κB essential modulator | MAP 3-kinase, MAP kinase kinase kinase | BAFF, B-cell activating factor | ERK, extracellular-signal-regulated kinase | Fn14, fibroblast-growth-factor-inducible 14 | ABIN, A20-binding inhibitor of nuclear factor κB | GM-CSF, granulocyte–macrophage colony-stimulating factor | GSK, glycogen synthase kinase | Dif, Dorsal-related immunity factor | EBNA1, EBV nuclear antigen 1 | BMDM, bone-marrow-derived macrophage | NF-κB, nuclear factor κB | SCF, Skp1 | Imd, immune deficiency | F-box | IL, interleukin | MAP kinase, mitogen-activated protein kinase | EBV, Epstein–Barr virus | LPS, lipopolysaccharide | IFNβ, interferon-β | IκB, inhibitor of nuclear factor κB | TRAF, TNF-receptor-associated factor | TLR, Toll-like receptor | DC, dendritic cell | IKK, IκB kinase | GRR, glycine-rich region | Review | JNK, c-Jun N-terminal kinase | PGRP-LC, peptidoglycan recognition protein LC | ERK kinase | RANKL, receptor activator of NF-κB ligand | LTβR, lymphotoxin-β receptor | MIP, macrophage inflammatory protein | DD, death domain | HTLV-1, human T-cell leukaemia virus type 1 | MEK, MAP kinase | COX-2, cyclo-oxygenase-2 | TH2, T-helper 2 | TH1, T-helper 1 | LMP1, latent membrane protein 1 | TPL-2, tumour progression locus-2 | TWEAK, TNF-like weak inducer of apoptosis | Cul1 | PEST region, polypeptide sequence enriched in proline (P), glutamic acid (E), serine (S) and threonine (T) | RHD, Rel homology domain | nuclear factor κB (NF-κB) | NIK, NF-κB-inducing kinase | MEF, mouse embryo fibroblast | βTrCP, β-transducin repeat-containing protein
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 01/2003, Volume 23, Issue 1, pp. 402 - 413
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
ACTIVATION | UBIQUITIN LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | PRECURSOR P105 | ALPHA | RECEPTOR | P50 | PROTEINS | NF-KAPPA-B | HUMAN MONOCYTES | CELL BIOLOGY | Cell Growth and Development
Journal Article
05/2017
본 발명은 호흡기 감염, 특히 만성폐쇄폐병(COPD)과 같은 기저 호흡기 장애를 갖는 환자의 호흡기 감염을 치료하거나 예방하는 방법에 관한 것이다. 본 발명은 또한 COPD 또는 COPD 악화를 치료하거나 예방하는 방법에 관한 것이다. 본 발명은 특히 상기 방법에서 Notch 3... 
WINE | MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS | HYGIENE | ENZYMOLOGY | ORGANIC CHEMISTRY | COMPOSITIONS OR TEST PAPERS THEREFOR | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES | MEDICAL OR VETERINARY SCIENCE | MICROBIOLOGY | MEASURING | HUMAN NECESSITIES | BEER | MUTATION OR GENETIC ENGINEERING | SPIRITS | TESTING | METALLURGY | PEPTIDES | PROCESSES OF PREPARING SUCH COMPOSITIONS | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | BIOCHEMISTRY | CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES | CHEMISTRY | VINEGAR | PHYSICS
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