BMC Medical Genetics, ISSN 1471-2350, 09/2018, Volume 19, Issue 1, pp. 165 - 16
Ankylosing spondylitis (AS) results from the combined effects of susceptibility genes and environmental factors. Polymorphisms in genes regulating inflammation...
Case-control study | Single nucleotide polymorphism | SNP | Ankylosing spondylitis | Receptors, Tumor Necrosis Factor, Type I - immunology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Interleukin-17 - immunology | NF-kappa B - immunology | Male | Risk | Case-Control Studies | Interleukin-23 - genetics | Spondylitis, Ankylosing - immunology | Signal Transduction - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - immunology | Tumor Necrosis Factor-alpha - immunology | Adult | Female | Registries | Genetic Predisposition to Disease | Receptors, Interleukin - immunology | Spondylitis, Ankylosing - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - genetics | Gene Expression Regulation | Interleukin-17 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Receptors, Tumor Necrosis Factor, Type I - genetics | Receptors, Interleukin - genetics | Interleukin-23 - immunology | Toll-Like Receptor 1 - genetics | Homozygote | NF-kappa B - genetics | Denmark | Heterozygote | Polymorphism, Single Nucleotide | Toll-Like Receptor 1 - immunology | Spondylitis, Ankylosing - pathology | Drugs | Genes | Interleukin 23 | Biochemistry | Arthritis | Single-nucleotide polymorphism | Kinases | Interleukin 1 | Toll-like receptors | Tumor necrosis factor-TNF | NF-κB protein | Cytokines | Inflammation | Environmental factors | TLR4 protein | Tumor necrosis factor-α | Patients | Interleukin 17 | Interleukin 18 | Spondylitis | Hospitals | TLR1 protein | Tuberculosis | Medical prognosis | TNF inhibitors | Heritability | Protein-tyrosine-phosphatase
Case-control study | Single nucleotide polymorphism | SNP | Ankylosing spondylitis | Receptors, Tumor Necrosis Factor, Type I - immunology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Interleukin-17 - immunology | NF-kappa B - immunology | Male | Risk | Case-Control Studies | Interleukin-23 - genetics | Spondylitis, Ankylosing - immunology | Signal Transduction - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - immunology | Tumor Necrosis Factor-alpha - immunology | Adult | Female | Registries | Genetic Predisposition to Disease | Receptors, Interleukin - immunology | Spondylitis, Ankylosing - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - genetics | Gene Expression Regulation | Interleukin-17 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Receptors, Tumor Necrosis Factor, Type I - genetics | Receptors, Interleukin - genetics | Interleukin-23 - immunology | Toll-Like Receptor 1 - genetics | Homozygote | NF-kappa B - genetics | Denmark | Heterozygote | Polymorphism, Single Nucleotide | Toll-Like Receptor 1 - immunology | Spondylitis, Ankylosing - pathology | Drugs | Genes | Interleukin 23 | Biochemistry | Arthritis | Single-nucleotide polymorphism | Kinases | Interleukin 1 | Toll-like receptors | Tumor necrosis factor-TNF | NF-κB protein | Cytokines | Inflammation | Environmental factors | TLR4 protein | Tumor necrosis factor-α | Patients | Interleukin 17 | Interleukin 18 | Spondylitis | Hospitals | TLR1 protein | Tuberculosis | Medical prognosis | TNF inhibitors | Heritability | Protein-tyrosine-phosphatase
Journal Article
Nutrients, ISSN 2072-6643, 05/2017, Volume 9, Issue 5, p. 499
Chronic inflammatory diseases (CIDs), including Crohn's disease and ulcerative colitis (inflammatory bowel diseases, IBD), rheumatoid arthritis, psoriasis,...
Treatment outcome | Biomarker | Exercise | Patient related outcome measures (PROMs) | Western style diet (WSD) | Molecular epidemiology | Red meat | Personalized medicine | Food | Smoking | molecular epidemiology | LONG-TERM INTAKE | RHEUMATOID-ARTHRITIS | patient related outcome measures (PROMs) | EUROPEAN PROSPECTIVE COHORT | ANTI-TNF TREATMENT | CROHNS-DISEASE | REDUCED RISK | ULCERATIVE-COLITIS | SUSCEPTIBILITY LOCI | exercise | biomarker | treatment outcome | food | personalized medicine | red meat | BOWEL-DISEASE | NUTRITION & DIETETICS | POLYUNSATURATED FATTY-ACID | western style diet (WSD) | smoking | Dietary Proteins - administration & dosage | Life Style | Prospective Studies | Follow-Up Studies | Humans | Dietary Fiber - administration & dosage | Inflammatory Bowel Diseases - diagnosis | Male | Intestines - metabolism | Gene-Environment Interaction | Meat | Dietary Fats - administration & dosage | Female | Micronutrients - administration & dosage | Precision Medicine | Body Mass Index | Inflammatory Bowel Diseases - drug therapy | Smoking - therapy | Biomarkers - blood | Inflammatory Bowel Diseases - diet therapy | Diet | Denmark | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Fatty Acids, Unsaturated - administration & dosage | Metabolomics | Therapy | Inflammatory bowel diseases | Medical services | Decisions | Arthritis | Inflammatory diseases | Intestine | Cooperation | Uveitis | Genetics | Tumor necrosis factor-TNF | Feces | Pharmaceutical industry | Signatures | Urine | Psoriasis | Tools | Data processing | Gene expression | Patients | Diseases | Medicine | Inhibitors | Tumor necrosis factor | Rheumatoid arthritis | Collaboration | Proteomics | TNF inhibitors | Lifestyles | Ulcerative colitis | Tumors
Treatment outcome | Biomarker | Exercise | Patient related outcome measures (PROMs) | Western style diet (WSD) | Molecular epidemiology | Red meat | Personalized medicine | Food | Smoking | molecular epidemiology | LONG-TERM INTAKE | RHEUMATOID-ARTHRITIS | patient related outcome measures (PROMs) | EUROPEAN PROSPECTIVE COHORT | ANTI-TNF TREATMENT | CROHNS-DISEASE | REDUCED RISK | ULCERATIVE-COLITIS | SUSCEPTIBILITY LOCI | exercise | biomarker | treatment outcome | food | personalized medicine | red meat | BOWEL-DISEASE | NUTRITION & DIETETICS | POLYUNSATURATED FATTY-ACID | western style diet (WSD) | smoking | Dietary Proteins - administration & dosage | Life Style | Prospective Studies | Follow-Up Studies | Humans | Dietary Fiber - administration & dosage | Inflammatory Bowel Diseases - diagnosis | Male | Intestines - metabolism | Gene-Environment Interaction | Meat | Dietary Fats - administration & dosage | Female | Micronutrients - administration & dosage | Precision Medicine | Body Mass Index | Inflammatory Bowel Diseases - drug therapy | Smoking - therapy | Biomarkers - blood | Inflammatory Bowel Diseases - diet therapy | Diet | Denmark | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Fatty Acids, Unsaturated - administration & dosage | Metabolomics | Therapy | Inflammatory bowel diseases | Medical services | Decisions | Arthritis | Inflammatory diseases | Intestine | Cooperation | Uveitis | Genetics | Tumor necrosis factor-TNF | Feces | Pharmaceutical industry | Signatures | Urine | Psoriasis | Tools | Data processing | Gene expression | Patients | Diseases | Medicine | Inhibitors | Tumor necrosis factor | Rheumatoid arthritis | Collaboration | Proteomics | TNF inhibitors | Lifestyles | Ulcerative colitis | Tumors
Journal Article
BMJ Open, ISSN 2044-6055, 02/2018, Volume 8, Issue 2, p. e018166
IntroductionChronic inflammatory diseases (CIDs) are frequently treated with biological medications, specifically tumour necrosis factor inhibitors (TNFi))....
patient related outcome measures | biomarker and lifestyle | lifestyle and chronic inflammatory disease | treatment outcome | western style diet | personalized medicine | LONG-TERM INTAKE | RHEUMATOID-ARTHRITIS | MEDICINE, GENERAL & INTERNAL | CROHNS-DISEASE | LIFE-STYLE | FOOD FREQUENCY QUESTIONNAIRE | ULCERATIVE-COLITIS | ANKYLOSING-SPONDYLITIS | SHORT HEALTH SCALE | SULFATE-REDUCING BACTERIA | BOWEL-DISEASE | Uveitis - therapy | Life Style | Skin Diseases - therapy | Prognosis | Prospective Studies | Humans | Dietary Fiber - administration & dosage | Red Meat - adverse effects | Inflammation | Diet | Quality of Life | Meat Products - adverse effects | Chronic Disease | Research Design | Inflammatory Bowel Diseases - therapy | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Patient Reported Outcome Measures | Precision Medicine | Rheumatic Diseases - therapy | Psoriasis | Systematic review | Arthritis | Inflammatory diseases | Meat | Inflammatory bowel disease | Precision medicine | Immunotherapy | Rheumatoid arthritis | Tumor necrosis factor-TNF | Skin diseases | Health risk assessment | Dietary fiber
patient related outcome measures | biomarker and lifestyle | lifestyle and chronic inflammatory disease | treatment outcome | western style diet | personalized medicine | LONG-TERM INTAKE | RHEUMATOID-ARTHRITIS | MEDICINE, GENERAL & INTERNAL | CROHNS-DISEASE | LIFE-STYLE | FOOD FREQUENCY QUESTIONNAIRE | ULCERATIVE-COLITIS | ANKYLOSING-SPONDYLITIS | SHORT HEALTH SCALE | SULFATE-REDUCING BACTERIA | BOWEL-DISEASE | Uveitis - therapy | Life Style | Skin Diseases - therapy | Prognosis | Prospective Studies | Humans | Dietary Fiber - administration & dosage | Red Meat - adverse effects | Inflammation | Diet | Quality of Life | Meat Products - adverse effects | Chronic Disease | Research Design | Inflammatory Bowel Diseases - therapy | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Patient Reported Outcome Measures | Precision Medicine | Rheumatic Diseases - therapy | Psoriasis | Systematic review | Arthritis | Inflammatory diseases | Meat | Inflammatory bowel disease | Precision medicine | Immunotherapy | Rheumatoid arthritis | Tumor necrosis factor-TNF | Skin diseases | Health risk assessment | Dietary fiber
Journal Article
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 04/2019, Volume 49, Issue 7, pp. 890 - 903
Summary Background Anti‐tumor necrosis factor‐α (TNF‐α) is used for the treatment of severe cases of IBD, including Crohn's disease (CD) and ulcerative colitis...
PHARMACOLOGY & PHARMACY | INFLAMMASOMES | CROHNS-DISEASE | GENE | INFLIXIMAB | GASTROENTEROLOGY & HEPATOLOGY | Medical research | Care and treatment | Tumor necrosis factor | Analysis | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Chromosomes | Ulcerative colitis | Therapy | Inflammatory bowel diseases | Identification methods | Genes | Gene regulation | Single-nucleotide polymorphism | Signal transduction | Pathways | Intestine | Janus kinase 2 | Interleukin 1 | Toll-like receptors | Tumor necrosis factor-TNF | Colon | NF-κB protein | Crohn's disease | TLR4 protein | Regression analysis | Gene expression | Patients | Interleukin 18 | Inflammatory bowel disease | TLR2 protein
PHARMACOLOGY & PHARMACY | INFLAMMASOMES | CROHNS-DISEASE | GENE | INFLIXIMAB | GASTROENTEROLOGY & HEPATOLOGY | Medical research | Care and treatment | Tumor necrosis factor | Analysis | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Chromosomes | Ulcerative colitis | Therapy | Inflammatory bowel diseases | Identification methods | Genes | Gene regulation | Single-nucleotide polymorphism | Signal transduction | Pathways | Intestine | Janus kinase 2 | Interleukin 1 | Toll-like receptors | Tumor necrosis factor-TNF | Colon | NF-κB protein | Crohn's disease | TLR4 protein | Regression analysis | Gene expression | Patients | Interleukin 18 | Inflammatory bowel disease | TLR2 protein
Journal Article
5.
Full Text
Long-chain acyl-CoA esters in metabolism and signaling: Role of acyl-CoA binding proteins
Progress in Lipid Research, ISSN 0163-7827, 07/2015, Volume 59, pp. 1 - 25
Long-chain fatty acyl-CoA esters are key intermediates in numerous lipid metabolic pathways, and recognized as important cellular signaling molecules. The...
Signaling | ACBD | Acyl-CoA | Lipid metabolism | ACBP | CHOLECYSTOKININ-RELEASING PEPTIDE | MESSENGER-RNA EXPRESSION | BENZODIAZEPINE LIGAND OCTADECANEUROPEPTIDE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRITICAL MICELLE CONCENTRATION | COENZYME-A CARBOXYLASE | ACTIVATED-RECEPTOR-ALPHA | NUTRITION & DIETETICS | FATTY-ACID BIOSYNTHESIS | PEROXISOMAL LIPID-METABOLISM | LIVER ACETYL-COENZYME | HEPATOCYTE NUCLEAR FACTOR-4-ALPHA | Amino Acid Sequence | Acyl Coenzyme A - physiology | Animals | Carrier Proteins - metabolism | Signal Transduction | Humans | Diazepam Binding Inhibitor - physiology | Molecular Sequence Data | Esters | Lipid Metabolism | Biosynthetic Pathways | Physiological aspects | Chemical properties | Binding proteins | Apolipoproteins | Fatty acids | Protein binding
Signaling | ACBD | Acyl-CoA | Lipid metabolism | ACBP | CHOLECYSTOKININ-RELEASING PEPTIDE | MESSENGER-RNA EXPRESSION | BENZODIAZEPINE LIGAND OCTADECANEUROPEPTIDE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRITICAL MICELLE CONCENTRATION | COENZYME-A CARBOXYLASE | ACTIVATED-RECEPTOR-ALPHA | NUTRITION & DIETETICS | FATTY-ACID BIOSYNTHESIS | PEROXISOMAL LIPID-METABOLISM | LIVER ACETYL-COENZYME | HEPATOCYTE NUCLEAR FACTOR-4-ALPHA | Amino Acid Sequence | Acyl Coenzyme A - physiology | Animals | Carrier Proteins - metabolism | Signal Transduction | Humans | Diazepam Binding Inhibitor - physiology | Molecular Sequence Data | Esters | Lipid Metabolism | Biosynthetic Pathways | Physiological aspects | Chemical properties | Binding proteins | Apolipoproteins | Fatty acids | Protein binding
Journal Article
Cell Reports, ISSN 2211-1247, 12/2013, Volume 5, Issue 5, pp. 1403 - 1412
We previously reported that mice deficient in acyl-CoA-binding protein (ACBP) display a delayed metabolic adaptation to weaning. This includes a delayed...
TARGETED DISRUPTION | LIGAND-BINDING | CHOLESTEROL | COA-BINDING PROTEIN | FATTY-ACID-METABOLISM | GENE-EXPRESSION | ACYL-COA | SKIN BARRIER | SACCHAROMYCES-CEREVISIAE | ACBP | CELL BIOLOGY | Adaptation, Physiological | Epidermis - metabolism | Weaning | Mice, Inbred C57BL | Adipose Tissue, White - metabolism | Sterol Regulatory Element Binding Proteins - metabolism | Hepatocytes - metabolism | Sterol Regulatory Element Binding Proteins - genetics | Lipolysis | Mice, Knockout | Body Water - metabolism | Diazepam Binding Inhibitor - genetics | Diazepam Binding Inhibitor - metabolism | Animals | Keratinocytes - metabolism | Mice
TARGETED DISRUPTION | LIGAND-BINDING | CHOLESTEROL | COA-BINDING PROTEIN | FATTY-ACID-METABOLISM | GENE-EXPRESSION | ACYL-COA | SKIN BARRIER | SACCHAROMYCES-CEREVISIAE | ACBP | CELL BIOLOGY | Adaptation, Physiological | Epidermis - metabolism | Weaning | Mice, Inbred C57BL | Adipose Tissue, White - metabolism | Sterol Regulatory Element Binding Proteins - metabolism | Hepatocytes - metabolism | Sterol Regulatory Element Binding Proteins - genetics | Lipolysis | Mice, Knockout | Body Water - metabolism | Diazepam Binding Inhibitor - genetics | Diazepam Binding Inhibitor - metabolism | Animals | Keratinocytes - metabolism | Mice
Journal Article
2007, ISBN 8779171087, 506
Book
1989, ISBN 8750028731, 265
Book
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