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Pharmaceuticals, ISSN 1424-8247, 06/2019, Volume 12, Issue 2, p. 93
Iron dyshomeostasis is a feature of Alzheimer’s disease (AD). The impact of iron on AD is attributed to its interactions with the central proteins of AD... 
senescence | ferroptosis | Alzheimer’s disease | iron homeostasis | chelators
Journal Article
Pharmaceuticals (Basel, Switzerland), ISSN 1424-8247, 06/2019, Volume 12, Issue 2
Iron dyshomeostasis is a feature of Alzheimer's disease (AD). The impact of iron on AD is attributed to its interactions with the central proteins of AD... 
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P666 - P666
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, p. P666
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 11/2016, Volume 60, Issue 3, pp. 325 - 335
Apolipoprotein E (ApoE) plays a crucial role in the homeostatic control of lipids in both the periphery and the central nervous system (CNS). In humans, ApoE... 
Neurochemistry | Neurology | Neurosciences | Biomedicine | Alzheimer’s disease | Apolipoprotein E | Neurodegeneration | Proteomics | Iron | Cell Biology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2017, Volume 127, Issue 12, pp. 4365 - 4378
Molybdenum cofactor deficiency (MoCD) is an autosomal recessive inborn error of metabolism characterized by neurodegeneration and death in early childhood. The... 
ENCEPHALOPATHY | MEDICINE, RESEARCH & EXPERIMENTAL | BIOLOGICAL FUNCTION | GEPHYRIN | METABOLISM | CALCIUM | INJURY | SULFITE OXIDASE DEFICIENCY | MOLECULAR-BASIS | DEHYDROGENASE | INBORN-ERRORS | Cysteine - analogs & derivatives | Metal Metabolism, Inborn Errors - metabolism | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Synapses - pathology | Neurodegenerative Diseases - drug therapy | Tungsten Compounds - toxicity | Synapses - metabolism | HEK293 Cells | Organophosphorus Compounds - pharmacology | Metal Metabolism, Inborn Errors - drug therapy | Cysteine - metabolism | GABAergic Neurons - metabolism | Calcium Signaling | Disease Models, Animal | Memantine - pharmacology | Neurodegenerative Diseases - pathology | Metal Metabolism, Inborn Errors - pathology | Neurodegenerative Diseases - genetics | GABAergic Neurons - pathology | Neurodegenerative Diseases - metabolism | Animals | Pterins - pharmacology | Mice | Neurons | Physiological aspects | GABA | Aspartate | Brain damage | Calpain | Glutamate | Molybdenum | Metabolism, Inborn errors of | Methyl aspartate | Care and treatment | Cellular signal transduction | Research | Inborn errors of metabolism | Glutamic acid receptors (ionotropic) | Homeostasis | Antagonists | Infants | Calcium influx | Proteins | Neurotoxicity | γ-Aminobutyric acid | Metabolites | Neurodegeneration | Rodents | Children | Urine | Enzymes | N-Methyl-D-aspartic acid receptors | Metabolism | Gephyrin | Memantine | Molecular modelling | Excitotoxicity | Mutation | Alzheimers disease | Brain injury | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e85258
Rationale: Preeclampsia is a devastating medical complication of pregnancy which leads to maternal and fetal morbidity and mortality. While the etiology of... 
WOMEN | MULTIDISCIPLINARY SCIENCES | PREGNANCY COMPLICATIONS | PLACENTAL GROWTH-FACTOR | SOLUBLE ENDOGLIN | RISK | PREECLAMPSIA | GLOMERULAR CAPILLARY WALL | PERMSELECTIVITY | TYROSINE KINASE 1 | ANGIOGENIC FACTORS | Venous Thrombosis - drug therapy | Humans | Venous Thrombosis - blood | Fibrinolytic Agents - metabolism | Pre-Eclampsia - urine | Heparin, Low-Molecular-Weight - therapeutic use | Venous Thrombosis - urine | Pregnancy | Glomerular Filtration Rate - drug effects | Pre-Eclampsia - drug therapy | Fibrinolytic Agents - therapeutic use | Pre-Eclampsia - blood | Heparin, Low-Molecular-Weight - metabolism | Protein Binding | Adult | Female | Vascular Endothelial Growth Factor Receptor-1 - urine | Vascular Endothelial Growth Factor Receptor-1 - blood | Tyrosine | Sulfates | Pregnant women | Vascular endothelial growth factor | Health aspects | Chromatography | Alternative splicing | Nephrology | Biochemistry | Molecular weight | Proteins | Angiogenesis | Etiology | Low molecular weights | Rodents | Masking | Growth factors | Binding | Urine | Heparan sulfate | Cation exchange | Hypertension | Enzymes | Signs and symptoms | Proteoglycans | Kidneys | Internal medicine | Fetuses | Gynecology | Cation exchanging | Pre-eclampsia | Obstetrics | Patients | Morbidity | Vascular endothelial growth factor receptors | Medicine | Serum levels | Studies | Preeclampsia | Heparan sulfate proteoglycans | In vivo methods and tests | Heparin | Sulfate | Binding sites | Kidney transplantation
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 01/2014, Volume 53, Issue 2, pp. 961 - 971
Molybdenum enzymes contain at least one pyranopterin dithiolate (molybdopterin, MPT) moiety that coordinates Mo through two dithiolate (dithiolene) sulfur... 
Journal Article
Inorganic chemistry, ISSN 0020-1669, 1/2014, Volume 53, Issue 2, pp. 961 - 971
Molybdenum enzymes contain at least one pyranopterin dithiolate (molybdopterin, MPT) moiety that coordinates Mo through two dithiolate (dithiolene) sulfur... 
Journal Article
Brain, ISSN 0006-8950, 12/2010, Volume 133, Issue 12, pp. 3778 - 3794
Anomalous hippocampal inhibition is involved in temporal lobe epilepsy, and reduced gephyrin immunoreactivity in the temporal lobe epilepsy hippocampus has... 
CABA(A) receptor | Molybdenum cofactor | Cellular stress | Epilepsy | Exon skipping | Gephyrin | Hippocampus | RNA splicing | epilepsy | hippocampus | TEMPORAL-LOBE EPILEPSY | RAT | INTRACELLULAR PH | GLYCINE RECEPTOR | gephyrin | molybdenum cofactor | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | GABA(A) RECEPTOR SUBTYPES | CLINICAL NEUROLOGY | cellular stress | GABA(A) receptor | exon skipping | SYNAPSES | MOUSE MODEL | GABAERGIC SYNAPTIC-TRANSMISSION | TONIC INHIBITION | Humans | Seizures - metabolism | Electroencephalography | Pteridines - metabolism | Coenzymes - metabolism | Metalloproteins - metabolism | Synapses - metabolism | Transfection | Epilepsy, Temporal Lobe - genetics | Membrane Proteins - isolation & purification | Membrane Proteins - genetics | Alternative Splicing - genetics | Carrier Proteins - biosynthesis | Cells, Cultured | Gene Expression Regulation - physiology | Rats | Epilepsy, Temporal Lobe - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | DNA - genetics | Gene Expression Regulation - drug effects | Carrier Proteins - genetics | Hippocampus - metabolism | Microscopy, Confocal | Membrane Proteins - biosynthesis | Patch-Clamp Techniques | Animals | Green Fluorescent Proteins - biosynthesis | Carrier Proteins - isolation & purification | Fluorescent Antibody Technique | Receptors, GABA-A - physiology | Electrophysiological Phenomena
Journal Article
Brain, ISSN 0006-8950, 12/2010, Volume 133, pp. 3778 - 3794
Anomalous hippocampal inhibition is involved in temporal lobe epilepsy, and reduced gephyrin immunoreactivity in the temporal lobe epilepsy hippocampus has... 
Journal Article
2013, 1. Aufl., ISBN 1461460921, 352
Taurine 8 represents the combined efforts of investigators on the roles of the amino acid taurine on human health and disease. The chapters covered in this... 
Taurine | Human physiology
eBook
2012, 2012, JIMD Reports, ISBN 9783642280955, Volume 5
Molybdenum cofactor deficiency (MoCD) is a rare inherited metabolic disorder characterized by severe and progressive neurological damage mainly caused by the... 
Human Genetics | Pediatrics | Biomedicine | Human Physiology | Metabolic Diseases | Endogenous amino acid | Sulfite oxidase | Interday precision | High performance liquid chromatography analysis | High performance liquid chromatography
Book Chapter