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Drug Metabolism and Disposition, ISSN 0090-9556, 12/2019, Volume 47, Issue 12, pp. 1368 - 1371
Journal Article
Drug Discovery Today, ISSN 1359-6446, 10/2019
Journal Article
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 11/2019, Volume 36, Issue 11, pp. 1 - 10
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 09/2019, p. dmd.119.088872
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 07/2019, Volume 108, Issue 7, pp. 2500 - 2504
Accurately predicting the hepatic clearance of compounds using to extrapolation (IVIVE) is crucial within the pharmaceutical industry. However, several groups... 
clearance | in vitro/in vivo correlation(s) (IVIVC) | hepatic clearance | in vitro/in vivo correlation(s) (IVIVC) | CHEMISTRY, MEDICINAL | METABOLIC-CLEARANCE | PROTEIN-BINDING | FATTY-ACIDS | MODEL | INTRINSIC CLEARANCE | CHEMISTRY, MULTIDISCIPLINARY | FRESH | PREDICTION | CRYOPRESERVED HEPATOCYTES | PHARMACOLOGY & PHARMACY | LIVER-MICROSOMES | DRUG-METABOLISM
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 92 - 12
Journal Article
DRUG METABOLISM AND DISPOSITION, ISSN 0090-9556, 05/2019, Volume 47, Issue 5, pp. 525 - 534
Fasiglifam, a potent and highly selective agonist of G protein-coupled receptor 40, was developed for the treatment of type 2 diabetes mellitus. However, phase... 
TRANSPORT | HEPATOCYTES | PHARMACOKINETICS | EFFICACY | SAFETY | INJURY | PHARMACOLOGY & PHARMACY | RECEPTOR 40 AGONIST | HEPATIC-UPTAKE | TAK-875 | JAPANESE PATIENTS | Toxicity | Ducts | Liver | Body weight | Diabetes mellitus | Ions | Mass spectroscopy | Flow rates | Dosage | Bile duct | Proteins | Toxicology | Ionization | Dogs | Flow velocity | Mass spectrometry | Diabetes mellitus (non-insulin dependent) | Carbon 14 | Bile
Journal Article
Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 01/2018, Volume 33, Issue 1, pp. S2 - S2
Journal Article
DRUG METABOLISM AND DISPOSITION, ISSN 0090-9556, 09/2019, Volume 47, Issue 9, pp. 1004 - 1012
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 3/2017, Volume 34, Issue 3, pp. 619 - 628
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 02/2019, Volume 105, Issue 2, pp. 326 - 328
Variability is the enemy of therapeutics. With respect to bioequivalence (BE), it is the mandate of regulatory agencies to understand and control this... 
PHARMACOLOGY & PHARMACY
Journal Article
The AAPS Journal, ISSN 1550-7416, 11/2019, Volume 21, Issue 6, pp. 1 - 6
The emergence and continued evolution of the transporter field has caused re-evaluation and refinement of the original principles surrounding drug disposition.... 
Biochemistry, general | Biotechnology | Biomedicine | transporters | volume of distribution | Pharmacy | clearance | Pharmacology/Toxicology | mean residence time | half-life | DRUG | INHIBITION | METABOLISM | VOLUME | PHARMACOLOGY & PHARMACY | MODEL | HEPATIC-CLEARANCE | Drugstores | Pharmacogenetics
Journal Article
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