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1. Full Text A-101 Understanding for targeting the HIV reservoir
by Benkirane, Monsef
Journal of acquired immune deficiency syndromes (1999), ISSN 1525-4135, 04/2018, Volume 77, p. 33
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2. Full Text SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4 + T-cells
by Descours, Benjamin and Cribier, Alexandra and Chable-Bessia, Christine and Ayinde, Diana and Rice, Gillian and Crow, Yanick and Yatim, Ahmad and Schwartz, Olivier and Laguette, Nadine and Benkirane, Monsef
Retrovirology, ISSN 1742-4690, 10/2012, Volume 9, Issue 1, pp. 87 - 87
HIV-1 | Reverse transcription | Restriction | T-cell | SAMHD1 | Quiescent CD4 | Life Sciences & Biomedicine | Science & Technology | Virology | HIV-1 - pathogenicity | Viral Regulatory and Accessory Proteins - immunology | Humans | DNA, Viral - metabolism | SAM Domain and HD Domain-Containing Protein 1 | Monomeric GTP-Binding Proteins - immunology | Viral Regulatory and Accessory Proteins - metabolism | Reverse Transcription | CD4-Positive T-Lymphocytes - immunology | Host-Pathogen Interactions | HIV-1 - immunology | Monomeric GTP-Binding Proteins - metabolism | CD4-Positive T-Lymphocytes - virology | Infection | Cellular proteins | Care and treatment | Genes | CD4 lymphocytes | DNA synthesis | Genetic aspects | Disease susceptibility | Genetic transcription | T cells | HIV (Viruses) | Health aspects | Index Medicus | Life Sciences | Genetics | Quiescent CD4+ T-cell
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3. Full Text SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
by Laguette, Nadine and Sobhian, Bijan and Casartelli, Nicoletta and Ringeard, Mathieu and Chable-Bessia, Christine and Ségéral, Emmanuel and Yatim, Ahmad and Emiliani, Stéphane and Schwartz, Olivier and Benkirane, Monsef
Nature (London), ISSN 0028-0836, 06/2011, Volume 474, Issue 7353, pp. 654 - 657
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Biological and medical sciences | Microbiology | Virology | Cell Line | Humans | DNA, Viral - metabolism | Gene Silencing | SAM Domain and HD Domain-Containing Protein 1 | Myeloid Cells - virology | Monomeric GTP-Binding Proteins - genetics | Viral Regulatory and Accessory Proteins - metabolism | HIV-1 - physiology | Monomeric GTP-Binding Proteins - metabolism | Virus Replication | U937 Cells | Myeloid Cells - metabolism | HeLa Cells | Proteasome Endopeptidase Complex - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | HIV Infections - metabolism | Physiological aspects | Research | Diagnosis | Dendritic cells | HIV infection | Proteins | Infections | Acquired immune deficiency syndrome--AIDS | Mass spectrometry | Viral infections | Index Medicus | HIV Infections | HIV-1 | Dendritic Cells | Monomeric GTP-Binding Proteins | Proteasome Endopeptidase Complex | Viral Regulatory and Accessory Proteins | Myeloid Cells | Life Sciences | Genetics | DNA, Viral | Hela Cells
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4. Full Text Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1
by Cribier, Alexandra and Descours, Benjamin and Valadão, AnaLuizaChaves and Laguette, Nadine and Benkirane, Monsef
Cell reports (Cambridge), ISSN 2211-1247, 04/2013, Volume 3, Issue 4, pp. 1036 - 1043
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Line | HIV-1 - metabolism | Leukocytes, Mononuclear - metabolism | Virus Replication - drug effects | Antiviral Agents - pharmacology | Phosphorylation | Humans | CD4-Positive T-Lymphocytes - metabolism | SAM Domain and HD Domain-Containing Protein 1 | Molecular Sequence Data | Monomeric GTP-Binding Proteins - genetics | CD4-Positive T-Lymphocytes - immunology | CDC2 Protein Kinase - metabolism | Cyclin A2 - metabolism | Sequence Alignment | Animals | Monomeric GTP-Binding Proteins - metabolism | Interferon Type I - pharmacology | Base Sequence | Leukocytes, Mononuclear - immunology | Index Medicus
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5. Full Text Regulation of HIV-1 gene expression
by Benkirane, Monsef
Retrovirology, ISSN 1742-4690, 09/2013, Volume 10, Issue S1, pp. O16 - O16
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6. Full Text CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
by Descours, Benjamin and Petitjean, Gaël and López-Zaragoza, José-Luis and Bruel, Timothée and Raffel, Raoul and Psomas, Christina and Reynes, Jacques and Lacabaratz, Christine and Levy, Yves and Schwartz, Olivier and Lelievre, Jean Daniel and Benkirane, Monsef
Nature (London), ISSN 0028-0836, 03/2017, Volume 543, Issue 7646, pp. 564 - 567
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Proviruses - isolation & purification | Humans | DNA, Viral - analysis | Gene Expression Profiling | Virus Latency - drug effects | Receptors, IgG - metabolism | HIV Infections - immunology | HIV-1 - growth & development | Proviruses - genetics | HIV-1 - isolation & purification | Cell Division | HEK293 Cells | Anti-HIV Agents - therapeutic use | CD4-Positive T-Lymphocytes - virology | HIV Infections - blood | Cell Separation | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Up-Regulation - genetics | HIV-1 - genetics | Proviruses - growth & development | Virus Replication | HIV Infections - drug therapy | Virus Latency - immunology | Virus Latency - genetics | T cells | HIV (Viruses) | Health aspects | Proteins | Lymphocytes | Human immunodeficiency virus--HIV | Gene expression | Viral infections | Deoxyribonucleic acid--DNA | Virology | Index Medicus | Life Sciences | Human health and pathology
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7. Full Text How Samhd1 changes our view of viral restriction
by Laguette, Nadine and Benkirane, Monsef
Trends in immunology, ISSN 1471-4906, 2011, Volume 33, Issue 1, pp. 26 - 33
Allergy and Immunology | Life Sciences & Biomedicine | Immunology | Science & Technology | Adaptive Immunity | HIV-1 - immunology | Animals | Monomeric GTP-Binding Proteins - metabolism | Signal Transduction | Virus Replication | Humans | SAM Domain and HD Domain-Containing Protein 1 | Monomeric GTP-Binding Proteins - immunology | Virus diseases | Enzymes | Polypeptides | Editing | Viruses | Amino acids | Infections | Genomes | Apolipoproteins | Proteins | Studies | Acquired immune deficiency syndrome--AIDS | Viral infections | Deoxyribonucleic acid--DNA | Immune system | Acquisitions & mergers | Index Medicus | Life Sciences | Genetics
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8. Full Text Descours et al. reply
by Descours, Benjamin and Petitjean, Gael and Benkirane, Monsef
Nature (London), ISSN 0028-0836, 09/2018, Volume 561, Issue 7723, pp. E29 - E29
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Flow cytometry | Infections | Lymphocytes | Human immunodeficiency virus--HIV | Deoxyribonucleic acid--DNA | Life Sciences | Genetics
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9. Full Text SAMHD1 acts at stalled replication forks to prevent interferon induction
by Coquel, Flavie and Silva, Maria-Joao and Técher, Hervé and Zadorozhny, Karina and Sharma, Sushma and Nieminuszczy, Jadwiga and Mettling, Clément and Dardillac, Elodie and Barthe, Antoine and Schmitz, Anne-Lyne and Promonet, Alexy and Cribier, Alexandra and Sarrazin, Amélie and Niedzwiedz, Wojciech and Lopez, Bernard and Costanzo, Vincenzo and Krejci, Lumir and Chabes, Andrei and Benkirane, Monsef and Lin, Yea-Lih and Pasero, Philippe
Nature (London), ISSN 0028-0836, 05/2018, Volume 557, Issue 7703, pp. 57 - 61
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | SAM Domain and HD Domain-Containing Protein 1 - metabolism | RecQ Helicases - metabolism | DNA, Single-Stranded - metabolism | Humans | DNA Replication | Inflammation - immunology | SAM Domain and HD Domain-Containing Protein 1 - deficiency | Interferon Type I - immunology | Checkpoint Kinase 1 - metabolism | Inflammation - metabolism | HEK293 Cells | Interferon Type I - metabolism | Cytosol - metabolism | Inflammation - prevention & control | Membrane Proteins - metabolism | HeLa Cells | Nucleotidyltransferases - metabolism | MRE11 Homologue Protein - metabolism | Physiological aspects | DNA replication | Interferon | Observations | Cytokines | Single-stranded DNA | DNA damage | CHK1 protein | Genomes | Kinases | DNA repair | Cytosol | Replication forks | DNA biosynthesis | Exonuclease | Microscopy | MRE11 protein | Replication | Mutation | Deoxyribonucleic acid--DNA | Cellular stress response | Cancer | Index Medicus | Life Sciences | Genetics
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10. Full Text SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
by Lahouassa, Hichem and Daddacha, Waaqo and Hofmann, Henning and Ayinde, Diana and Logue, Eric C and Dragin, Loïc and Bloch, Nicolin and Maudet, Claire and Bertrand, Matthieu and Gramberg, Thomas and Pancino, Gianfranco and Priet, Stéphane and Canard, Bruno and Laguette, Nadine and Benkirane, Monsef and Transy, Catherine and Landau, Nathaniel R and Kim, Baek and Margottin-Goguet, Florence
Nature immunology, ISSN 1529-2908, 03/2012, Volume 13, Issue 3, pp. 223 - 228
Life Sciences & Biomedicine | Immunology | Science & Technology | Cell Line | Humans | SAM Domain and HD Domain-Containing Protein 1 | Monomeric GTP-Binding Proteins - immunology | Macaca mulatta | Monomeric GTP-Binding Proteins - genetics | Nucleotides - metabolism | Animals | HIV-1 - physiology | Monomeric GTP-Binding Proteins - metabolism | Virus Replication | Intracellular Space - metabolism | Mice | Macrophages - immunology | Care and treatment | Deoxyribonucleotides | Physiological aspects | Genetic aspects | Research | Macrophages | HIV infection | Health aspects | Risk factors | Index Medicus | Life Sciences | Genetics
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11. Full Text Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac
by Brandariz-Nuñez, Alberto and Valle-Casuso, Jose C and White, Tommy E and Laguette, Nadine and Benkirane, Monsef and Brojatsch, Jurgen and Diaz-Griffero, Felipe
Retrovirology, ISSN 1742-4690, 06/2012, Volume 9, Issue 1, pp. 49 - 49
Degradation | HIV-1 | Restriction | SIV | Nuclear localization | SAMHD | Vpx | Life Sciences & Biomedicine | Science & Technology | Virology | HIV-1 - pathogenicity | Humans | SAM Domain and HD Domain-Containing Protein 1 | Cytoplasm - metabolism | Restriction Mapping | Reverse Transcription | Simian Immunodeficiency Virus - genetics | Cell Nucleus - metabolism | Proteolysis | U937 Cells | Cell Nucleus - virology | Active Transport, Cell Nucleus | Acquired Immunodeficiency Syndrome - virology | HIV-1 - metabolism | Simian Immunodeficiency Virus - pathogenicity | Mutagenesis, Site-Directed | HIV Infections - virology | Viral Regulatory and Accessory Proteins - genetics | Cytoplasm - virology | Nuclear Localization Signals - metabolism | Monomeric GTP-Binding Proteins - genetics | HIV-1 - genetics | Viral Regulatory and Accessory Proteins - metabolism | Cell Nucleus - genetics | Monomeric GTP-Binding Proteins - metabolism | Alleles | Simian Immunodeficiency Virus - metabolism | HeLa Cells | Mutation | Infection | Allelomorphism | Amino acids | Dendritic cells | HIV (Viruses) | Macrophages | Index Medicus | Life Sciences | Genetics
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12. Full Text Interaction between HIV and its host: role for viral and cellular sncRNA
by Benkirane, Monsef
Retrovirology, ISSN 1742-4690, 10/2011, Volume 8, Issue S2, pp. O12 - O12
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